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Alvydas Mikulskis · SciRah

Researcher profile · Semantic Scholar

Alvydas Mikulskis

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Alvydas Mikulskis — researcher profile on SciRah

h-index: 19
Works: 43
Citations: 4,699

Most-cited papers

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease
J. Sevigny, P. Chiao, T. Bussiere, P. Weinreb +24 more
2016Nature2,755 citations
Semantic Scholar
Current state of Alzheimer’s fluid biomarkers
J. Molinuevo, S. Ayton, R. Batrla, M. Bednar +15 more
2018Acta Neuropathologica479 citations Open access
Semantic Scholar
First-in-human, double-blind, placebo-controlled, single-dose escalation study of aducanumab (BIIB037) in mild-to-moderate Alzheimer's disease
Jim Ferrero, Leslie Williams, H. Stella, K. Leitermann +3 more
2016Alzheimer's & Dementia159 citations Open access
Semantic Scholar
High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures.
M. Lopez, Alvydas Mikulskis, S. Kuzdzal, D. Bennett +16 more
2005Clinical Chemistry139 citations
Semantic Scholar
Concordance Between Different Amyloid Immunoassays and Visual Amyloid Positron Emission Tomographic Assessment
S. Janelidze, Josef Pannee, Alvydas Mikulskis, P. Chiao +3 more
2017JAMA Neurology128 citations Open access
Semantic Scholar
A novel, high-throughput workflow for discovery and identification of serum carrier protein-bound peptide biomarker candidates in ovarian cancer samples.
M. Lopez, Alvydas Mikulskis, S. Kuzdzal, E. Golenko +15 more
2007Clinical Chemistry112 citations
Semantic Scholar
The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review
O. Hansson, Alvydas Mikulskis, A. Fagan, C. Teunissen +13 more
2018Alzheimer's & Dementia109 citations Open access
Semantic Scholar
Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies
S. Gopal, Alvydas Mikulskis, R. Gold, R. Fox +2 more
2017Multiple Sclerosis102 citations
Semantic Scholar
Solution ELISA as a platform of choice for development of robust, drug tolerant immunogenicity assays in support of drug development.
Alvydas Mikulskis, Dave Yeung, M. Subramanyam, L. Amaravadi
2011JIM - Journal of Immunological Methods93 citations
Semantic Scholar
Emerging Technologies to Increase Ligand Binding Assay Sensitivity
Saloumeh K. Fischer, A. Joyce, M. Spengler, Tong-Yuan Yang +3 more
2014AAPS Journal86 citations Open access
Semantic Scholar
Anti-drug Antibody Validation Testing and Reporting Harmonization
H. Myler, J. Pedras-Vasconcelos, Kelli R Phillips, C. Hottenstein +38 more
2021AAPS Journal71 citations Open access
Semantic Scholar
Housekeeping genes in cancer: normalization of array data.
Anis H. Khimani, A. Mhashilkar, Alvydas Mikulskis, Mike O'Malley +6 more
2005BioTechniques66 citations Open access
Semantic Scholar
Addendum: The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease
J. Sevigny, P. Chiao, T. Bussiere, P. Weinreb +24 more
2017Nature65 citations
Semantic Scholar
Evaluation of highly sensitive immunoassay technologies for quantitative measurements of sub-pg/mL levels of cytokines in human serum.
Dave Yeung, Shawn Ciotti, S. Purushothama, Elham Gharakhani +5 more
2016JIM - Journal of Immunological Methods65 citations
Semantic Scholar
2013 White Paper on recent issues in bioanalysis: 'hybrid'--the best of LBA and LCMS.
Lauren F. Stevenson, F. Garofolo, Binodh S. Desilva, Isabelle Dumont +57 more
2013Bioanalysis63 citations
Semantic Scholar
The fliA gene encoding sigma 28 in Yersinia enterocolitica
M. Iriarte, Isabelle Stainier, Alvydas Mikulskis, G. Cornelis
1995Journal of Bacteriology44 citations Open access
Semantic Scholar
Phosphopeptide analysis by directly coupling two-dimensional planar electrochromatography/thin-layer chromatography with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Venkateswarlu Panchagnula, Alvydas Mikulskis, Linan Song, Yang Wang +8 more
2007Journal of Chromatography A38 citations
Semantic Scholar
Proteomic patterns for classification of ovarian cancer and CTCL serum samples utilizing peak pairs indicative of post‐translational modifications
Chen-Wei Liu, Nancy Shea, S. Rucker, Linda K. Harvey +12 more
2007Proteomics20 citations
Semantic Scholar
A Multi-site In-depth Evaluation of the Quanterix Simoa from a User’s Perspective
A. Chunyk, A. Joyce, Saloumeh K. Fischer, Mark Dysinger +5 more
2017AAPS Journal19 citations
Semantic Scholar
High‐content proteomics: Fluorescence multiplexing using an integrated, high‐sensitivity, multiwavelength charge‐coupled device imaging system
M. Lopez, Alvydas Mikulskis, E. Golenko, Klaus Herick +4 more
2003Proteomics17 citations
Semantic Scholar
Recommendations for the development and validation of confirmatory anti-drug antibody assays.
Darshana Jani, R. Marsden, Alvydas Mikulskis, C. Gleason +5 more
2015Bioanalysis11 citations
Semantic Scholar
Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples
M. Lopez, Alvydas Mikulskis, E. Golenko, S. Melov +5 more
2004Electrophoresis10 citations
Semantic Scholar
Clinical Pharmacology: Advances and Applications Dovepress Pharmacokinetics of Daclizumab High-yield Process with Repeated Administration of the Clinical Subcutaneous Regimen in Patients with Relapsing- Remitting Multiple Sclerosis
Jonathan Q. Tran, A. Othman, Alvydas Mikulskis, P. Wolstencroft +1 more
10 citations
Semantic Scholar
Amyloid beta-positive subjects exhibit longitudinal network-specific reductions in spontaneous brain activity.
B. Avants, R. Hutchison, Alvydas Mikulskis, Cristian Salinas-Valenzuela +3 more
2019Neurobiology of Aging9 citations Open access
Semantic Scholar
A Robust Biomarker Discovery Pipeline for High-Performance Mass Spectrometry Data
W. Fisher, K. Rosenblatt, D. Fishman, G. Whiteley +6 more
2007J. Bioinform. Comput. Biol.9 citations
Semantic Scholar
The fliA Gene Encoding s in Yersinia enterocolitica
M. Iriarte, Isabelle Stainier, Alvydas Mikulskis, G. Cornelis
19958 citations
Semantic Scholar
Novel data analysis methods to overcome cut point challenges and enable comprehensive assessment of antidrug binding activity in confirmatory assays.
Alvydas Mikulskis, Dave Yeung, Weiping Chen, Devangi Mehta +1 more
2013JIM - Journal of Immunological Methods6 citations
Semantic Scholar
Performance validation of an improved Xenon‐arc lamp‐based CCD camera system for multispectral imaging in proteomics
E. Scrivener, B. Boghigian, E. Golenko, A. Bogdanova +6 more
2005Proteomics5 citations
Semantic Scholar
Pharmacokinetics of daclizumab high-yield process with repeated administration of the clinical subcutaneous regimen in patients with relapsing-remitting multiple sclerosis
Jonathan Q. Tran, A. A. Othman, Alvydas Mikulskis, P. Wolstencroft +1 more
20163 citations
Semantic Scholar
Pharmacokinetics of Daclizumab High-Yield Process (DAC HYP) with Repeated Administration of the Clinical Subcutaneous Regimen in Subjects With Relapsing-Remitting Multiple Sclerosis (P3.257)
Jonathan Q. Tran, A. Othman, Yaoshi Wu, Alvydas Mikulskis +2 more
2015Neurology2 citations
Semantic Scholar
Biomarker discovery and analysis platform: application to Alzheimer's disease.
S. Kuzdzal, M. Lopez, Alvydas Mikulskis, E. Golenko +13 more
2005BioTechniques2 citations Open access
Semantic Scholar
The impact of pre-analytical variables on measuring CSF biomarkers for Alzheimer’s disease diagnosis: A review
O. Hansson, Alvydas Mikulskis, A. Fagan, Charlotte E. Teunissen +14 more
20191 citations
Semantic Scholar
Evaluation of Immunogenicity in Patients with Multiple Sclerosis Treated with Daclizumab HYP (P1.147)
L. Amaravadi, Alvydas Mikulskis, N. Lucas, K. Riester +2 more
2015Neurology1 citations
Semantic Scholar
A Multi-site In-depth Evaluation of the Quanterix Simoa from a User’s Perspective
A. Chunyk, A. Joyce, Saloumeh K. Fischer, Mark Dysinger +5 more
2017AAPS Journal0 citations
Semantic Scholar
Development of a plug and play ImmunoPCR technique for the analysis of biomolecules.
S. Gopal, S. Purushothama, Alvydas Mikulskis, Lauren F. Stevenson
2017Bioanalysis0 citations
Semantic Scholar
Evaluation of Immunogenicity in Multiple Sclerosis Patients Treated with Daclizumab-HYP During the SELECT and SELECTION Clinical Trials (P3.177)
L. Amaravadi, Alvydas Mikulskis, M. McNeill, K. Riester +3 more
2014Neurology0 citations
Semantic Scholar
P1–348: Pharmacokinetics of BIIB037 in people with mild‐to‐moderate Alzheimer's disease (AD) participating in a phase 1 dose‐escalation trial
Jim Ferrero, H. Stella, K. Leitermann, Alvydas Mikulskis +2 more
20130 citations
Semantic Scholar
FLORBETAPIR PET, FDG-PET AND MRI IN PEOPLE WITH DOWN SYNDROME WITH AND WITHOUT SYMPTOMATIC ALZHEIMER’S DISEASE OF APOE GENOTYPE ON CLINICAL TRIAL OUTCOMES TRACER KINETIC MODEL-BASED
Ke-Wei Chen, J. Rogers, Carolyn Liebsack, D. Bandy +31 more
20130 citations
Semantic Scholar
P75-T Selective Detection of Phosphoproteins and Subsequent Enrichment of Constituent Phosphopeptides for Phosphorylation Site Analysis by Mass Spectrometry
Alvydas Mikulskis, Susan Kramer, A. Bogdanova, H. Xie +4 more
20070 citations
Semantic Scholar
Proteomic analysis of mitochondrial proteins.
M. Lopez, S. Melov, Felicity Johnson, Nicole Nagulko +4 more
2004International review of neurobiology0 citations
Semantic Scholar
Signal amplification on microarrays: techniques and advances in tyramide signal amplification (TSA)
K. Adler, M. C. Tyler, Alvydas Mikulskis, Mike O'Malley +6 more
2001SPIE BiOS0 citations
Semantic Scholar
Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples (vol. 25, Issue 15, pp. 2557‐2563)
M. Lopez, Alvydas Mikulskis, E. Golenko, S. Melov +5 more
0 citations Open access
Semantic Scholar
Amyloid beta e positive subjects exhibit longitudinal network-speci ﬁ c reductions in spontaneous brain activity
B. Avants, R. Hutchison, Alvydas Mikulskis, Cristian Salinas-Valenzuela +2 more
0 citations
Semantic Scholar

Frequent co-authors

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E. Golenko×13
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E. Golenko — researcher profile on SciRah
M. Lopez×10
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M. Lopez — researcher profile on SciRah
S. Kuzdzal×8
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S. Kuzdzal — researcher profile on SciRah
L. Amaravadi×7
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L. Amaravadi — researcher profile on SciRah

Wayne F. Patton

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J. Sevigny — researcher profile on SciRah

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Jim Ferrero — researcher profile on SciRah

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Dave Yeung — researcher profile on SciRah

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J. Elkins — researcher profile on SciRah

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Leslie Williams — researcher profile on SciRah

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