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S. Hazen · SciRah

Researcher profile · Semantic Scholar

S. Hazen

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S. Hazen — researcher profile on SciRah

h-index: 121
Works: 561
Citations: 51K

Most-cited papers

Gut microbiota and cardiovascular disease
M. Witkowski, Taylor L. Weeks, S. Hazen
2020Circulation Research842 citations Open access
Semantic Scholar
Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism.
A. Haghikia, F. Zimmermann, P. Schumann, A. Jasina +28 more
2021European Heart Journal334 citations Open access
Semantic Scholar
Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.
J. Hartiala, Yi Han, Qiong Jia, James R. Hilser +55 more
2021European Heart Journal229 citations Open access
Semantic Scholar
Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production
Marco Orecchioni, K. Kobiyama, H. Winkels, Y. Ghosheh +25 more
2022Science216 citations Open access
Semantic Scholar
Gut microbes impact stroke severity via the trimethylamine-N-oxide pathway
Wei-Fei Zhu, K. Romano, Lin Li, J. Buffa +14 more
2021Cell Host and Microbe148 citations Open access
Semantic Scholar
Two distinct gut microbial pathways contribute to meta-organismal production of phenylacetylglutamine with links to cardiovascular disease
Yi-Jun Zhu, M. Dwidar, I. Nemet, J. Buffa +15 more
2022Cell Host and Microbe147 citations Open access
Semantic Scholar
Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection
D. Adlam, Timothy M. Olson, N. Combaret, J. Kovacic +233 more
2019Journal of the American College of Cardiology144 citations Open access
Semantic Scholar
Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression
Nisreen Nimer, Ibrahim Choucair, Ze-Neng Wang, I. Nemet +12 more
2020Metabolism: Clinical and Experimental139 citations Open access
Semantic Scholar
Gut microbiota-derived trimethylamine N-oxide contributes to abdominal aortic aneurysm through inflammatory and apoptotic mechanisms
Tyler W. Benson, K. Conrad, Xin-Min S. Li, Ze-Neng Wang +23 more
2023Circulation132 citations Open access
Semantic Scholar
Gut microbiota-generated phenylacetylglutamine and heart failure
K. Romano, I. Nemet, Prasenjit Prasad Saha, A. Haghikia +20 more
2022Circulation: Heart Failure131 citations Open access
Semantic Scholar
Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice
Wen-Chao Zhang, Aika Miikeda, J. Zuckerman, Xun Jia +11 more
2021Scientific Reports126 citations Open access
Semantic Scholar
Rise in Blood Pressure Observed Among US Adults During the COVID-19 Pandemic
L. Laffin, H. Kaufman, Zhen Chen, J. Niles +3 more
2021Circulation120 citations Open access
Semantic Scholar
Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality.
I. Nemet, Xin-Min S. Li, A. Haghikia, Lin Li +12 more
2023European Heart Journal118 citations Open access
Semantic Scholar
Vascular endothelial Tissue Factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis.
Marco Witkowski, M. Witkowski, J. Friebel, J. Buffa +16 more
2021Cardiovascular Research104 citations Open access
Semantic Scholar
Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes
S. A. Winther, Jens C. Øllgaard, Nete Tofte, L. Tarnow +9 more
2019Diabetes Care100 citations Open access
Semantic Scholar
The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism
J. Buffa, K. Romano, M. Copeland, D. Cody +29 more
2021Nature Microbiology98 citations Open access
Semantic Scholar
Trimethylamine N-Oxide levels are associated with NASH in obese subjects with type 2 diabetes
P. León-Mimila, H. Villamil-Ramírez, Xin-Min S. Li, D. Shih +19 more
2020Diabetes & Metabolism97 citations Open access
Semantic Scholar
Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality.
Stefan J. Schunk, M. Kleber, W. März, S. Pang +64 more
2021European Heart Journal87 citations Open access
Semantic Scholar
Trimethyllysine, a trimethylamine N-oxide precursor, provides near- and long-term prognostic value in patients presenting with acute coronary syndromes.
Xin-Min S. Li, S. Obeid, Ze-Neng Wang, Benjamin J Hazen +15 more
2019European Heart Journal85 citations Open access
Semantic Scholar
Small Molecule Inhibition of Gut Microbial Choline Trimethylamine Lyase Activity Alters Host Cholesterol and Bile Acid Metabolism.
P. Pathak, Robert N. Helsley, Amanda L. Brown, J. Buffa +11 more
2020American Journal of Physiology. Heart and Circulatory Physiology83 citations Open access
Semantic Scholar
Longitudinal Plasma Measures of Trimethylamine N‐Oxide and Risk of Atherosclerotic Cardiovascular Disease Events in Community‐Based Older Adults
Yu-Jin Lee, I. Nemet, Ze-Neng Wang, Heidi T. M. Lai +12 more
2021Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease80 citations Open access
Semantic Scholar
Effects of Lifestyle Intervention on Plasma Trimethylamine N-Oxide in Obese Adults
M. Erickson, S. Malin, Ze-Neng Wang, J. M. Brown +2 more
2019Nutrients76 citations Open access
Semantic Scholar
Plasma trimethylamine N-oxide (TMAO) levels predict future risk of coronary artery disease in apparently healthy individuals in the EPIC-Norfolk Prospective Population Study
W. H. Wilson Tang, Xin-Min S. Li, Yu-Ping Wu, Ze-Neng Wang +5 more
2021American Heart Journal72 citations Open access
Semantic Scholar
Differential effect of short-term popular diets on TMAO and other cardio-metabolic risk markers.
J. Park, M. Miller, J. Rhyne, Z. Wang +1 more
2019NMCD. Nutrition Metabolism and Cardiovascular Diseases72 citations
Semantic Scholar
Trimethylamine N-oxide is associated with long-term mortality risk: the multi-ethnic study of atherosclerosis.
Meng Wang, Xin-Min S. Li, Ze-Neng Wang, M. C. de Oliveira Otto +11 more
2023European Heart Journal71 citations Open access
Semantic Scholar
A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis
Lucas J. Osborn, Karlee B Schultz, William Massey, B. DeLucia +16 more
2021bioRxiv69 citations Open access
Semantic Scholar
Chronic opioid use modulates human enteric microbiota and intestinal barrier integrity
Angélica Cruz-Lebrón, Ramon Johnson, C. Mazahery, Zach Troyer +5 more
2021Gut microbes65 citations Open access
Semantic Scholar
Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality
A. Molinaro, I. Nemet, Pierre Bel Lassen, R. Chakaroun +15 more
2023JACC. Heart failure62 citations Open access
Semantic Scholar
Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study
Annefleur M. Koopen, Julia J. Witjes, K. Wortelboer, S. Majait +24 more
2021Gut61 citations Open access
Semantic Scholar
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms
R. Schugar, Christy M. Gliniak, Lucas J. Osborn, William J. Massey +29 more
2020bioRxiv58 citations Open access
Semantic Scholar
Association of Trimethylamine N-Oxide and Related Metabolites in Plasma and Incident Type 2 Diabetes
R. Lemaitre, P. Jensen, Ze-Neng Wang, A. Fretts +9 more
2021JAMA Network Open56 citations Open access
Semantic Scholar
Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice
Xue-Song Zhang, Y. Yin, Jincheng Wang, T. Battaglia +25 more
2021Cell Host and Microbe55 citations Open access
Semantic Scholar
Circulating trimethylamine N-oxide levels following fish or seafood consumption
Ze-Neng Wang, W. H. Wilson Tang, T. O’Connell, Erwin Garcia +5 more
2022European Journal of Nutrition51 citations Open access
Semantic Scholar
Gut Microbiome-Dependent Metabolic Pathways and Risk of Lethal Prostate Cancer: Prospective Analysis of a PLCO Cancer Screening Trial Cohort
Chad A. Reichard, B. Naelitz, Ze-Neng Wang, Xun Jia +5 more
2021Cancer Epidemiology, Biomarkers and Prevention48 citations Open access
Semantic Scholar
Association of Trimethylamine N-Oxide and Metabolites With Mortality in Older Adults
A. Fretts, S. Hazen, P. Jensen, M. Budoff +12 more
2022JAMA Network Open47 citations Open access
Semantic Scholar
Effects of Smoking and Smoking Cessation on the Intestinal Microbiota
Marcus G Sublette, Tzu-Wen L. Cross, C. Korcarz, K. Hansen +6 more
2020medRxiv46 citations Open access
Semantic Scholar
Gut Microbiota‐Dependent Trimethylamine N‐oxide and Cardiovascular Outcomes in Patients With Prior Myocardial Infarction: A Nested Case Control Study From the PEGASUS‐TIMI 54 Trial
B. Gencer, Xin-Min S. Li, Yared Gurmu, M. Bonaca +9 more
2020Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease43 citations Open access
Semantic Scholar
Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice
Robert N. Helsley, T. Miyata, Anagha Kadam, Venkateshwari Varadharajan +32 more
2022bioRxiv42 citations Open access
Semantic Scholar
Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A Randomized Clinical Trial
J. Wilcox, Sarah M. Skye, B. Graham, Allyson Zabell +9 more
2021American Journal of Medicine38 citations Open access
Semantic Scholar
A novel recurrent COL5A1 genetic variant is associated with a dysplasia-associated arterial disease exhibiting dissections and fibromuscular dysplasia
J. Richer, Hannah L. Hill, Yu Wang, Min-Lee Yang +24 more
2020Arteriosclerosis, Thrombosis and Vascular Biology36 citations Open access
Semantic Scholar
The Nutritional Supplement L-Alpha Glycerylphosphorylcholine Promotes Atherosclerosis
Ze-Neng Wang, Jennie E. Hazen, Xun Jia, E. Org +13 more
2021International Journal of Molecular Sciences35 citations Open access
Semantic Scholar
Gut microbiota involvement in ventricular remodeling post myocardial infarction: New insights into how to heal a broken heart
A. McMillan, S. Hazen
2019Circulation35 citations Open access
Semantic Scholar
Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation
S. Kim, S. Bale, Priyanka Verma, Qian-Qian Wan +10 more
2022iScience34 citations Open access
Semantic Scholar
Stable isotope dilution mass spectrometry quantification of hydrogen sulfide and thiols in biological matrices
Hind Malaeb, Ibrahim Choucair, Ze-Neng Wang, Xinmin Li +6 more
2022Redox Biology32 citations Open access
Semantic Scholar
Gut microbiota-dependent metabolite trimethylamine N-oxide (TMAO) and cardiovascular risk in patients with suspected functionally relevant coronary artery disease (fCAD)
M. Amrein, Xin-Min S. Li, J. Walter, Ze-Neng Wang +16 more
2022Clinical Research in Cardiology32 citations Open access
Semantic Scholar
Fecal Microbiome Composition Does Not Predict Diet‐Induced TMAO Production in Healthy Adults
M. Ferrell, P. Bazeley, Ze-Neng Wang, B. Levison +8 more
2021Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease32 citations Open access
Semantic Scholar
Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria
S. A. Winther, Jens C. Øllgaard, T. Hansen, B. J. von Scholten +8 more
2021PLoS ONE30 citations Open access
Semantic Scholar
Relation of Statin Use to Gut Microbial Trimethylamine N-Oxide and Cardiovascular Risk
Daniel Y. Li, Xinmin Li, T. Chaikijurajai, Lin Li +3 more
2022American Journal of Cardiology29 citations Open access
Semantic Scholar
Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia
A. Georges, J. Albuisson, T. Berrandou, D. Dupré +33 more
2020Cardiovascular Research27 citations Open access
Semantic Scholar
Mitochondrial DNA Content Is Linked to Cardiovascular Disease Patient Phenotypes
Ruipeng Wei, Y. Ni, P. Bazeley, S. Grandhi +5 more
2021Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease26 citations Open access
Semantic Scholar

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