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Careen K. Tang · SciRah

Researcher profile · Semantic Scholar

Careen K. Tang

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Careen K. Tang — researcher profile on SciRah

h-index: 28
Works: 50
Citations: 2,839

Most-cited papers

AEE788
P. Traxler, P. Allegrini, R. Brandt, Joseph Brueggen +11 more
2004Cancer Research329 citations Open access
Semantic Scholar
Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster.
D. Haile, T. Rouault, Careen K. Tang, J. Chin +2 more
1992Proceedings of the National Academy of Sciences of the United States of America246 citations Open access
Semantic Scholar
A regulated RNA binding protein also possesses aconitase activity.
S. Kaptain, W. Downey, Careen K. Tang, C. Philpott +5 more
1991Proceedings of the National Academy of Sciences of the United States of America193 citations Open access
Semantic Scholar
Epidermal growth factor receptor vIII enhances tumorigenicity in human breast cancer.
Careen K. Tang, X. Gong, D. Moscatello, A. Wong +1 more
2000Cancer Research154 citations
Semantic Scholar
Unusual mRNA pseudoknot structure is recognized by a protein translational repressor.
Careen K. Tang, D. Draper
1989Cell132 citations
Semantic Scholar
Evidence of high incidence of EGFRvIII expression and coexpression with EGFR in human invasive breast cancer by laser capture microdissection and immunohistochemical analysis
Hong Ge, X. Gong, Careen K. Tang
2002International Journal of Cancer131 citations Open access
Semantic Scholar
Overexpression of KAI1 suppresses in vitro invasiveness and in vivo metastasis in breast cancer cells.
Xiao-Hong Yang, Lisa L. Wei, Careen K. Tang, R. Slack +2 more
2001Cancer Research131 citations
Semantic Scholar
Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo.
E. Atlas, M. Cardillo, I. Mehmi, Hengameh Zahedkargaran +2 more
2003Molecular Cancer Research128 citations
Semantic Scholar
Epidermal growth factor and betacellulin mediate signal transduction through co‐expressed ErbB2 and ErbB3 receptors
M. Alimandi, Ling-Mei Wang, D. Bottaro, Chong-Chou Lee +6 more
1997EMBO Journal127 citations Open access
Semantic Scholar
Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer
Miaw-Sheue Tsai, Lisa A. Shamon-Taylor, I. Mehmi, Careen K. Tang +1 more
2003Oncogene126 citations Open access
Semantic Scholar
Involvement of Heregulin-β2 in the Acquisition of the Hormone-independent Phenotype of Breast Cancer Cells
Careen K. Tang, C. Pérez, T. Grunt, C. Waibel +2 more
1996115 citations
Semantic Scholar
Ribozyme-mediated down-regulation of ErbB-4 in estrogen receptor-positive breast cancer cells inhibits proliferation both in vitro and in vivo.
Careen K. Tang, Xiao Zheng Wu Concepcion, M. Milan, X. Gong +2 more
1999Cancer Research92 citations
Semantic Scholar
Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII
W. Han, Tao Zhang, Hong Yu, J. Foulke +1 more
2006Cancer Biology & Therapy84 citations Open access
Semantic Scholar
Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis
H. Feng, Bo Hu, M. Jarzynka, Yan-Xin Li +12 more
2012Proceedings of the National Academy of Sciences of the United States of America77 citations Open access
Semantic Scholar
KAI1 protein is down-regulated during the progression of human breast cancer.
Xiao-Hong Yang, Lisa L. Wei, Careen K. Tang, R. Slack +2 more
2000Clinical Cancer Research76 citations
Semantic Scholar
Cripto-1 Indirectly Stimulates the Tyrosine Phosphorylation oferb B-4 through a Novel Receptor*
C. Bianco, Subha Kannan, M. De Santis, M. Seno +8 more
1999Journal of Biological Chemistry76 citations Open access
Semantic Scholar
Heregulin regulates the actin cytoskeleton and promotes invasive properties in breast cancer cell lines.
M. Hijazi, Erik W. Thompson, Careen K. Tang, P. Coopman +4 more
1999International Journal of Oncology75 citations
Semantic Scholar
3,3′-Diindolylmethane (DIM) Inhibits the Growth and Invasion of Drug-Resistant Human Cancer Cells Expressing EGFR Mutants
Massod Rahimi, Kai Huang, Careen K. Tang
2010Cancer Letters46 citations Open access
Semantic Scholar
Induction of sensitivity to doxorubin and etoposide by transfection of MCF-7 breast cancer cells with here β-2
L. Harris, Li Yang, Careen K. Tang, Da-Jun Yang +1 more
199845 citations
Semantic Scholar
The significance ofheregulin in breast cancer tumor progression and drug resistance
Ruth Lupu, M. Cardillo, Cheryl Cho, Lyndsay Harris +5 more
1996Breast Cancer Research and Treatment45 citations
Semantic Scholar
Evidence for allosteric coupling between the ribosome and repressor binding sites of a translationally regulated mRNA.
Careen K. Tang, D. Draper
1990Biochemistry45 citations
Semantic Scholar
TOB suppresses breast cancer tumorigenesis
S. O'Malley, Hua Su, Tao Zhang, Crystal Ng +2 more
2009International Journal of Cancer41 citations
Semantic Scholar
Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance
K. Chang, S. Tsai, Shang-Hung Chen, Hsiao-Hui Tsou +11 more
2013Journal of Biomedical Sciences40 citations Open access
Semantic Scholar
EGFRvIII-Induced Estrogen-Independence, Tamoxifen-Resistance Phenotype Correlates with PgR expression and Modulation of Apoptotic Molecules in Breast Cancer
Yang Zhang, Hua Su, Massod Rahimi, Ryan Tochihara +1 more
2009International Journal of Cancer39 citations Open access
Semantic Scholar
An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein
T. Rouault, D. Haile, W. Downey, C. Philpott +7 more
1992Biometals38 citations
Semantic Scholar
EGFR Variant-Mediated Invasion by Enhanced CXCR4 Expression through Transcriptional and Post-Translational Mechanisms
Massod Rahimi, Jessica A George, Careen K. Tang
2010International Journal of Cancer37 citations Open access
Semantic Scholar
Co-expression of EGFRvIII with ErbB-2 enhances tumorigenesis: EGFRvIII mediated constitutively activated and sustained signaling pathways, whereas EGF-induced a transient effect on EGFR-mediated signaling pathways
Hong Yu, X. Gong, Xun-Yi Luo, W. Han +3 more
2008Cancer Biology & Therapy35 citations Open access
Semantic Scholar
ErbB-4 ribozymes abolish neuregulin-induced mitogenesis.
Careen K. Tang, D. J. Goldstein, Jennifer Payne, F. Czubayko +4 more
1998Cancer Research29 citations
Semantic Scholar
Suppression of EGFRvIII‐mediated proliferation and tumorigenesis of breast cancer cells by ribozyme
Xun-Yi Luo, X. Gong, Careen K. Tang
2003International Journal of Cancer26 citations Open access
Semantic Scholar
EGF Family Receptors and Their Ligands in Human Cancer
Careen K. Tang, M. Lippman
199823 citations
Semantic Scholar
Inhibition of histamine release and phosphatidylcholine metabolism by 5'-deoxy-5'-isobutylthio-3-deazaadenosine.
Yutaka Morita, R. Siraganian, Careen K. Tang, Peter K. Chiang
1982Biochemical Pharmacology18 citations
Semantic Scholar
Chemokine receptor CXCR4-mediated transformation of mammary epithelial cells by enhancing multiple RTKs expression and deregulation of the p53/MDM2 axis.
Hua Su, Elias J. Sobrino Najul, Theodore A. Toth, Crystal Ng +3 more
2011Cancer Letters17 citations
Semantic Scholar
CXCR4 Suppression Attenuates EGFRvIII-Mediated Invasion and Induces p38 MAPK-Dependent Protein Trafficking and Degradation of EGFRvIII in Breast Cancer Cells
Massod Rahimi, Theodore A. Toth, Careen K. Tang
2011Cancer Letters12 citations Open access
Semantic Scholar
Tumor progression and metastasis from genetic to microenvironmental determinants
Y. D. de Clerck, B. Weissman, Di-Hua Yu, R. Parsons +15 more
2006Cancer Biology & Therapy2 citations Open access
Semantic Scholar
18 - Role of Epidermal Growth Factor Receptor in Breast Carcinoma
Careen K. Tang
20022 citations
Semantic Scholar
Metastasis in Breast Cancer Cells in Vivo Invasiveness and in Vitro Suppresses KAI 1 Overexpression of Updated Version
Xiao-Hong R. Yang, Lisa L. Wei, Careen K. Tang, R. Slack +2 more
20012 citations
Semantic Scholar
Production of biologically active IgG hinge-tag soluble epidermal growth factor receptors (ErbB)
Takayuki Otani, Toshihiro Hashizume, Tadahiro Nagaoka, T. Fukuda +3 more
2010Biotechnology Letters1 citations
Semantic Scholar
Co-expression of an EGFR mutant with ErbB-2 enhanced motility and invasion
Hong Yu, S. O'Malley, Careen K. Tang
20051 citations
Semantic Scholar
Advances in Brief KAI 1 Protein Is Down-Regulated during the Progression of Human Breast Cancer 1
Xiao-Hong R. Yang, Lisa L. Wei, Careen K. Tang, R. Slack +2 more
20001 citations
Semantic Scholar
of cytokinesis
H. Feng, Bo Hu, M. Jarzynka, Yan-Xin Li +12 more
1 citations
Semantic Scholar
Epidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB 2 and ErbB 3 receptors and ErbB
M. Alimandi, D. Bottaro, Angera H. Kuo, Mark Frankel +2 more
20130 citations
Semantic Scholar
Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance
K. Chang, S. Tsai, Shang-Hung Chen, Hsiao-Hui Tsou +11 more
2013Journal of Biomedical Sciences0 citations Open access
Semantic Scholar
Abstract 2390: EGFR variant III act as the major determinant factors in the EGFR/PI3K/AKT pathway for the survival outcome of oral cancer patients.
K. Chang, S. Tsai, Shang-Hung Chen, Hsiao-Hui Tsou +4 more
20130 citations
Semantic Scholar
ErbB-4 Ribozymes Abolish Neuregulin-induced Mitogenesis 1
Careen K. Tang, D. Goldstein, Jennifer, Payne +8 more
20060 citations
Semantic Scholar
A Novel Molecular Targeting of a Tumor-Specific Oncogenic Mutant Receptor in Human Prostate Cancer
Careen K. Tang
20050 citations
Semantic Scholar
Anticorps monoclonaux specifiques d'egfrviii, ribozymes d'egfrviii et utilisations en detection, traitement ou prevention de cancer associe a l'egfrviii
Careen K. Tang
20030 citations
Semantic Scholar
Ribozyme Targeting the Novel Fusion Junction of EGFRvIII in Breast Cancer
Careen K. Tang
20030 citations Open access
Semantic Scholar
The new development of Class I tyrosine kinase superfamily in human cancer
Careen K. Tang
20010 citations
Semantic Scholar
Inhibition of heregulin expression blocks tumorigenicity and metastasis of breast cancer
Miaw-Sheue Tsai, Lisa A. Shamon-Taylor, I. Mehmi, Careen K. Tang +2 more
20010 citations
Semantic Scholar
Study the Pathogenic Role of ErbB-3, ErbB-4 and their Ligand Heregulin in Human Breast Cancer Cells.
Careen K. Tang
20000 citations
Semantic Scholar

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