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C. Redfield · SciRah

Researcher profile · Semantic Scholar

C. Redfield

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C. Redfield — researcher profile on SciRah

h-index: 36
Works: 173
Citations: 4,549

Most-cited papers

A Conserved Face of the Jagged/Serrate DSL Domain is Involved in Notch Trans-Activation and Cis-Inhibition
J. Cordle, S. Johnson, J.-Z. Tay, P. Roversi +10 more
2008Nature Structural &Molecular Biology274 citations Open access
Semantic Scholar
Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.
M. Dumoulin, Denis Canet, Alexander M. Last, E. Pardon +7 more
2005Journal of Molecular Biology111 citations Open access
Semantic Scholar
Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes.
J. Christodoulou, Göran Larsson, P. Fucini, S. Connell +7 more
2004Proceedings of the National Academy of Sciences of the United States of America91 citations Open access
Semantic Scholar
Exploitation of an iron transporter for bacterial protein antibiotic import
P. White, A. Joshi, P. Rassam, N. G. Housden +7 more
2017Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.
A. Russell, I. Westwood, M. Crawford, James Robinson +6 more
2009Bioorganic & Medicinal Chemistry79 citations Open access
Semantic Scholar
Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.
P. Chan, E. Pardon, L. Menzer, E. De Genst +13 more
2008Biochemistry78 citations
Semantic Scholar
The lipoprotein Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism
Joanna Szczepaniak, P. Holmes, K. Rajasekar, Renata Kaminska +7 more
2020Nature Communications77 citations Open access
Semantic Scholar
Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/LTBP Superfamily of Matrix Proteins
Sacha A. Jensen, S. Iqbal, E. Lowe, C. Redfield +1 more
2009Structure55 citations Open access
Semantic Scholar
Structure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril Assembly
D. Yadin, Ian B Robertson, Joanne McNaught-Davis, P. Evans +4 more
2013Structure43 citations Open access
Semantic Scholar
Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1
A. Kawamura, I. Westwood, L. Wakefield, Hilary Long +4 more
2008Biochemical Pharmacology41 citations Open access
Semantic Scholar
Characterization of the unfolded state of bovine α‐lactalbumin and comparison with unfolded states of homologous proteins
Julia Wirmer, H. Berk, R. Ugolini, C. Redfield +1 more
2006Protein Science39 citations Open access
Semantic Scholar
Ca2+-dependent Interface Formation in Fibrillin-1*
Sacha A. Jensen, A. Corbett, V. Knott, C. Redfield +1 more
2005Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies
P. C. Weisshuhn, D. Sheppard, P. Taylor, P. Whiteman +3 more
2016Structure36 citations Open access
Semantic Scholar
Water Mediation Is Essential to Nucleation of β-Turn Formation in Peptide Folding Motifs
S. Busch, C. Bruce, C. Redfield, C. Lorenz +1 more
2013Angewandte Chemie34 citations Open access
Semantic Scholar
Molecular Basis for Jagged-1/Serrate Ligand Recognition by the Notch Receptor
P. Whiteman, Beatriz Hernandez de Madrid, P. Taylor, De-Min Li +13 more
2013Journal of Biological Chemistry34 citations Open access
Semantic Scholar
Residual dipolar couplings: are multiple independent alignments always possible?
V. Higman, J. Boyd, L. J. Smith, C. Redfield
2010Journal of Biomolecular NMR33 citations Open access
Semantic Scholar
The Human α-Lactalbumin Molten Globule: Comparison of Structural Preferences at pH 2 and pH 7
Heike I. Rösner, C. Redfield
2009Journal of Molecular Biology33 citations Open access
Semantic Scholar
Probing the heme-binding site of the cytochrome c maturation protein CcmE.
Edgar M. Harvat, C. Redfield, J. M. Stevens, S. J. Ferguson
2009Biochemistry32 citations
Semantic Scholar
Cellular and molecular studies of Marfan syndrome mutations identify co-operative protein folding in the cbEGF12-13 region of fibrillin-1.
P. Whiteman, A. Willis, A. Warner, James Brown +2 more
2007Human Molecular Genetics32 citations
Semantic Scholar
Toxin import through the antibiotic efflux channel TolC
N. G. Housden, M. N. Webby, E. Lowe, T. El-Baba +4 more
2021Nature Communications30 citations Open access
Semantic Scholar
Plasticity of the TSG-6 HA-binding loop and mobility in the TSG-6-HA complex revealed by NMR and X-ray crystallography.
V. Higman, C. Blundell, D. Mahoney, C. Redfield +2 more
2007Journal of Molecular Biology29 citations Open access
Semantic Scholar
Active-site properties of the oxidized and reduced C-terminal domain of DsbD obtained by NMR spectroscopy.
D. Mavridou, J. M. Stevens, S. J. Ferguson, C. Redfield
2007Journal of Molecular Biology26 citations
Semantic Scholar
Structure of the terminal PCP domain of the non‐ribosomal peptide synthetase in teicoplanin biosynthesis
K. Haslinger, C. Redfield, M. Cryle
2015Proteins: Structure, Function, and Bioinformatics24 citations
Semantic Scholar
The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1
Ian B Robertson, Hans F. Dias, Isabelle H. Osuch, E. Lowe +3 more
2017Structure22 citations Open access
Semantic Scholar
Consequences of inducing intrinsic disorder in a high-affinity protein-protein interaction.
G. Papadakos, Amit Sharma, Lorna E Lancaster, R. Bowen +5 more
2015Journal of the American Chemical Society22 citations Open access
Semantic Scholar
Biophysical characterisation of fibulin-5 proteins associated with disease.
R. Schneider, Sacha A. Jensen, P. Whiteman, J. Mccullagh +2 more
2010Journal of Molecular Biology22 citations
Semantic Scholar
Probing the effect of temperature on the backbone dynamics of the human alpha-lactalbumin molten globule.
S. Ramboarina, C. Redfield
2008Journal of the American Chemical Society19 citations
Semantic Scholar
Structural Insights into Notch Receptor-Ligand Interactions.
P. Handford, Boguslawa Korona, R. Suckling, C. Redfield +1 more
2018Advances in Experimental Medicine and Biology18 citations
Semantic Scholar
Oxidation State-dependent Protein-Protein Interactions in Disulfide Cascades
D. Mavridou, E. Saridakis, Paraskevi Kritsiligkou, A. Goddard +3 more
2011Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Rapid collapse into a molten globule is followed by simple two-state kinetics in the folding of lysozyme from bacteriophage λ.
Alexandre di Paolo, Dorothée Balbeur, E. De Pauw, C. Redfield +1 more
2010Biochemistry18 citations
Semantic Scholar
Characterization of the molten globule of human serum retinol-binding protein using NMR spectroscopy.
L. Greene, R. Wijesinha-Bettoni, C. Redfield
2006Biochemistry18 citations
Semantic Scholar
Control of Periplasmic Interdomain Thiol:Disulfide Exchange in the Transmembrane Oxidoreductase DsbD
D. Mavridou, J. M. Stevens, A. Goddard, A. Willis +2 more
2009Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Local frustration determines loop opening during the catalytic cycle of an oxidoreductase
L. Stelzl, D. Mavridou, E. Saridakis, Diego Gonzalez +4 more
2020eLife13 citations Open access
Semantic Scholar
Conformational flexibility of GRASP proteins and their constituent PDZ subdomains reveals structural basis of their promiscuous interactome.
L. F. S. Mendes, Mariana R. B. Batista, P. Judge, A. Watts +2 more
2020The FEBS Journal13 citations Open access
Semantic Scholar
Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein
Patryk Ludzia, E. Lowe, G. Marcianò, S. Mohammed +2 more
2021Structure12 citations Open access
Semantic Scholar
Probing the urea dependence of residual structure in denatured human α-lactalbumin
V. Higman, Heike I. Rösner, R. Ugolini, L. Greene +2 more
2009Journal of Biomolecular NMR12 citations Open access
Semantic Scholar
The N1317H Substitution Associated with Leber Congenital Amaurosis Results in Impaired Interdomain Packing in Human CRB1 Epidermal Growth Factor-like (EGF) Domains*
Jason A Davis, P. Handford, C. Redfield
2007Journal of Biological Chemistry12 citations Open access
Semantic Scholar
The structural basis for high affinity binding of α1-acid glycoprotein to the potent antitumor compound UCN-01
Erik J. B. Landin, Christopher Williams, Sara A. Ryan, A. Bochel +6 more
2021Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Assignment of Protein NMR Spectra Using Heteronuclear NMR—A Tutorial
C. Redfield
201510 citations Open access
Semantic Scholar
An Extended Active-site Motif Controls the Reactivity of the Thioredoxin Fold
D. Mavridou, E. Saridakis, Paraskevi Kritsiligkou, Erin Mozley +2 more
2014Journal of Biological Chemistry10 citations Open access
Semantic Scholar
NMR Spectroscopic and Bioinformatic Analyses of the LTBP1 C-Terminus Reveal a Highly Dynamic Domain Organisation
Ian B Robertson, P. Handford, C. Redfield
2014PLoS ONE10 citations Open access
Semantic Scholar
The Dynamics of Lysozyme from Bacteriophage Lambda in Solution Probed by NMR and MD Simulations
L. J. Smith, Alice M. Bowen, Alexandre di Paolo, A. Matagne +1 more
2013ChemBioChem10 citations Open access
Semantic Scholar
The CcmC–CcmE interaction during cytochrome c maturation by System I is driven by protein–protein and not protein–heme contacts
S. H. Shevket, Diego Gonzalez, J. Cartwright, C. Kleanthous +3 more
2018Journal of Biological Chemistry9 citations Open access
Semantic Scholar
The Role of Active Site Flexible Loops in Catalysis and of Zinc in Conformational Stability of Bacillus cereus 569/H/9 β-Lactamase*
C. Montagner, M. Nigen, O. Jacquin, Nicolas Willet +6 more
2016Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Bacterial expression and in vitro refolding of limited fragments of the Notch receptor and its ligands.
P. Whiteman, C. Redfield, P. Handford
2014Methods in molecular biology8 citations
Semantic Scholar
Protonation linked equilibria and apparent affinity constants: the thermodynamic profile of the α-chymotrypsin–proflavin interaction
Gilles Bruylants, R. Wintjens, Y. Looze, C. Redfield +1 more
2007European Biophysics Journal8 citations
Semantic Scholar
1H, 13C and 15N assignments of EGF domains 4 to 7 of human Notch-1
P. C. Weisshuhn, P. Handford, C. Redfield
2014Biomolecular NMR Assignments7 citations
Semantic Scholar
Functional Characterization of the C-terminal Domain of the Cytochrome c Maturation Protein CcmE*
Edgar M. Harvat, J. M. Stevens, C. Redfield, S. J. Ferguson
2005Journal of Biological Chemistry7 citations Open access
Semantic Scholar
Quantitative High-Field NMR- and Mass Spectrometry-Based Fatty Acid Sequencing Reveals Internal Structure in Ru-Catalyzed Deuteration of Docosahexaenoic Acid.
Dong-Hao Wang, D. Vidović, Alasdair I. McKay, T. Darwish +13 more
2022Analytical Chemistry6 citations
Semantic Scholar
Developments in the Characterisation of the Catalytic Triad of α‐Chymotrypsin: Effect of the Protonation State of Asp102 on the 1H NMR Signals of His57
Gilles Bruylants, C. Redfield, K. Bartik
2007ChemBioChem6 citations
Semantic Scholar

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