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M. Grainger · SciRah

Researcher profile · Semantic Scholar

M. Grainger

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M. Grainger — researcher profile on SciRah

h-index: 32
Works: 51
Citations: 6,400

Most-cited papers

A proteomic view of the Plasmodium falciparum life cycle
L. Florens, M. Washburn, J. Raine, Robert M. Anthony +14 more
2002Nature1,309 citations
Semantic Scholar
In Brief
K. L. Le Roch, Ying-Yao Zhou, P. L. Blair, M. Grainger +7 more
2003Nature reviews genetics1,298 citations Open access
Semantic Scholar
Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle.
K. L. Le Roch, Jeffrey R. Johnson, L. Florens, Ying-Yao Zhou +8 more
2004Genome Research478 citations Open access
Semantic Scholar
A Role for the Protease Falcipain 1 in Host Cell Invasion by the Human Malaria Parasite
D. Greenbaum, A. Baruch, M. Grainger, Zbynek Bozdech +5 more
2002Science276 citations
Semantic Scholar
Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum.
Shirin Arastu-Kapur, E. Ponder, U. P. Fonović, S. Yeoh +6 more
2008Nature Chemical Biology256 citations
Semantic Scholar
Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach
M. Wright, B. Clough, M. Rackham, K. Rangachari +14 more
2013Nature Chemistry206 citations Open access
Semantic Scholar
The Malaria Parasite Cyclic GMP-Dependent Protein Kinase Plays a Central Role in Blood-Stage Schizogony
Helen M. Taylor, Louisa McRobert, M. Grainger, A. Sicard +4 more
2009Eukaryotic Cell196 citations Open access
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The Motor Complex of Plasmodium falciparum
Judith L. Green, Roxanne R. Rees-Channer, S. Howell, S. Martin +4 more
2008Journal of Biological Chemistry183 citations Open access
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Malaria parasite actin filaments are very short.
Stephan Schmitz, M. Grainger, S. Howell, L. Calder +4 more
2005Journal of Molecular Biology165 citations
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A Subtilisin-like Protein in Secretory Organelles of Plasmodium falciparum Merozoites*
M. Blackman, H. Fujioka, W. Stafford, M. Sajid +5 more
1998Journal of Biological Chemistry148 citations Open access
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The merozoite surface protein 6 gene codes for a 36 kDa protein associated with the Plasmodium falciparum merozoite surface protein-1 complex.
Carlotta Trucco, Delmiro Fernandez-Reyes, Steven Howell, W. Stafford +5 more
2001Molecular and biochemical parasitology (Print)132 citations
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The 22 kDa component of the protein complex on the surface of Plasmodium falciparum merozoites is derived from a larger precursor, merozoite surface protein 7.
Justin A. Pachebat, I. Ling, M. Grainger, Carlotta Trucco +4 more
2001Molecular and biochemical parasitology (Print)116 citations
Semantic Scholar
PCR-based gene synthesis as an efficient approach for expression of the A+T-rich malaria genome.
C. Withers-Martinez, E. Carpenter, F. Hackett, Barry K. Ely +3 more
1999Protein Engineering114 citations Open access
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Dual acylation of the 45 kDa gliding-associated protein (GAP45) in Plasmodium falciparum merozoites.
Roxanne R. Rees-Channer, S. Martin, Judith L. Green, Paul W. Bowyer +3 more
2006Molecular and biochemical parasitology (Print)113 citations
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Variation in the Expression of a Plasmodium falciparum Protein Family Implicated in Erythrocyte Invasion
Helen M. Taylor, M. Grainger, A. Holder
2002Infection and Immunity107 citations Open access
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Formation of the Food Vacuole in Plasmodium falciparum: A Potential Role for the 19 kDa Fragment of Merozoite Surface Protein 1 (MSP119)
A. Dluzewski, I. Ling, J. Hopkins, M. Grainger +4 more
2008PLoS ONE92 citations Open access
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The Plasmodium falciparum clag9 gene encodes a rhoptry protein that is transferred to the host erythrocyte upon invasion
I. Ling, L. Florens, Anton R. Dluzewski, O. Kaneko +10 more
2004Molecular Microbiology90 citations
Semantic Scholar
The MTIP-myosin A complex in blood stage malaria parasites.
Judith L. Green, S. Martin, Jeremy Fielden, Asimina Ksagoni +4 more
2006Journal of Molecular Biology88 citations
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Apical expression of three RhopH1/Clag proteins as components of the Plasmodium falciparum RhopH complex.
O. Kaneko, Brian Y. S. Yim Lim, Hideyuki Iriko, I. Ling +7 more
2005Molecular and biochemical parasitology (Print)88 citations
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Origin, kinetics of circulation and fate in vivo of the major excretory–secretory product of Acanthocheilonema viteae
W. Harnett, M. Worms, A. Kapil, M. Grainger +1 more
1989Parasitology81 citations
Semantic Scholar
PfSUB-2: a second subtilisin-like protein in Plasmodium falciparum merozoites.
F. Hackett, M. Sajid, C. Withers-Martinez, M. Grainger +1 more
1999Molecular and biochemical parasitology (Print)73 citations
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Extensive differential protein phosphorylation as intraerythrocytic Plasmodium falciparum schizonts develop into extracellular invasive merozoites
E. Lasonder, Judith L. Green, M. Grainger, G. Langsley +1 more
2015Proteomics68 citations
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Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum.
Paul W. Bowyer, R. S. Gunaratne, M. Grainger, C. Withers-Martinez +6 more
2007Biochemical Journal64 citations Open access
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Malaria Parasite Actin Polymerization and Filament Structure*
Stephan Schmitz, I. Schaap, J. Kleinjung, S. Harder +5 more
2010Journal of Biological Chemistry60 citations Open access
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Extensive proteolytic processing of the malaria parasite merozoite surface protein 7 during biosynthesis and parasite release from erythrocytes.
J. Pachebat, M. Kadekoppala, M. Grainger, A. Dluzewski +8 more
2007Molecular and biochemical parasitology (Print)58 citations
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PSLAP, a protein with multiple adhesive motifs, is expressed in Plasmodium falciparum gametocytes.
I. Delrieu, C. Waller, M. Mota, M. Grainger +2 more
2002Molecular and biochemical parasitology (Print)57 citations
Semantic Scholar
Plasmodium thrombospondin related apical merozoite protein (PTRAMP) is shed from the surface of merozoites by PfSUB2 upon invasion of erythrocytes.
Judith L. Green, L. Hinds, M. Grainger, E. Knuepfer +1 more
2006Molecular and biochemical parasitology (Print)53 citations
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Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development
Judith L. Green, R. Moon, D. Whalley, Paul W. Bowyer +13 more
2015Antimicrobial Agents and Chemotherapy51 citations Open access
Semantic Scholar
N-terminal amino acid sequence of the Plasmodium falciparum merozoite surface protein-1 polypeptides.
W. Stafford, Michael J. Blackman, Alan S. Harris, Shafrira Shai +2 more
1994Molecular and biochemical parasitology (Print)42 citations
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Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development
Judith L. Green, Yang Wu, V. Encheva, E. Lasonder +17 more
2020PLoS Pathogens41 citations Open access
Semantic Scholar
Novel Putative Glycosylphosphatidylinositol-Anchored Micronemal Antigen of Plasmodium falciparum That Binds to Erythrocytes
L. Hinds, Judith L. Green, E. Knuepfer, M. Grainger +1 more
2009Eukaryotic Cell40 citations Open access
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Deletion of the Plasmodium falciparum Merozoite Surface Protein 7 Gene Impairs Parasite Invasion of Erythrocytes
M. Kadekoppala, R. O'Donnell, M. Grainger, B. Crabb +1 more
2008Eukaryotic Cell37 citations Open access
Semantic Scholar
Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-1(19) mapped by TROSY NMR.
W. Morgan, Matthew J Lock, T. Frenkiel, M. Grainger +1 more
2004Molecular and biochemical parasitology (Print)32 citations
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Precise epitope mapping of malaria parasite inhibitory antibodies by TROSY NMR cross-saturation.
W. Morgan, T. Frenkiel, Matthew J Lock, M. Grainger +1 more
2005Biochemistry31 citations
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A novel Sushi domain-containing protein of Plasmodium falciparum.
Aisling H O'Keeffe, Judith L. Green, M. Grainger, A. Holder
2005Molecular and biochemical parasitology (Print)31 citations
Semantic Scholar
RON12, a novel Plasmodium-specific rhoptry neck protein important for parasite proliferation
E. Knuepfer, O. Suleyman, A. Dluzewski, U. Straschil +6 more
2013Cellular Microbiology30 citations Open access
Semantic Scholar
A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line.
E. D. Benavente, P. D. de Sessions, R. Moon, M. Grainger +9 more
2017International Journal of Parasitology26 citations Open access
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Association between circulating antigen and parasite load in a model filarial system, Acanthocheilonema viteae in jirds
William Harnett, M. J. Worms, M. Grainger, S. D. M. Pyke +1 more
1990Parasitology19 citations
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Inhibitory and neutral antibodies to Plasmodium falciparum MSP119 form ring structures with their antigen.
C. Dekker, C. Uthaipibull, L. Calder, Matthew J Lock +4 more
2004Molecular and biochemical parasitology (Print)18 citations
Semantic Scholar
Plasmodium falciparum aldolase and the C-terminal cytoplasmic domain of certain apical organellar proteins promote actin polymerization
S. Diaz, S. Martin, M. Grainger, S. Howell +2 more
2014Molecular and biochemical parasitology (Print)17 citations Open access
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The Binding of Plasmodium falciparum Adhesins and Erythrocyte Invasion Proteins to Aldolase Is Enhanced by Phosphorylation
S. Diaz, S. Martin, S. Howell, M. Grainger +3 more
2016PLoS ONE10 citations Open access
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Evaluation of the potential of excretions-secretions (E-S) ofLitomosoides carinii to substitute for human filarial E-S
W. Harnett, M. Grainger, M. Worms, R. Parkhouse
2004Parasitology Research5 citations
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Protein ubiquitylation is essential for the schizont to merozoite transition in Plasmodium falciparum blood-stage development
Yang Wu, V. Encheva, Judith L. Green, E. Lasonder +17 more
2019bioRxiv3 citations Open access
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Proteins of the parasite pellicle identified as ubiquitylated.
Judith L. Green, Yang Wu, V. Encheva, E. Lasonder +17 more
20200 citations Open access
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Plasmodium vivax N-myristoyltransferase in complex with a benzothiophene inhibitor
M. Wright, B. Clough, M. Rackham, J. Brannigan +10 more
20140 citations
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Plasmodium vivax N-myristoyltransferase in complex with YnC12-CoA thioester.
M. Wright, B. Clough, M. Rackham, J. Brannigan +10 more
20140 citations
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Plasmodium vivax N-myristoyltransferase in complex with a pyrazole sulphonamide inhibitor.
M. Wright, B. Clough, M. Rackham, J. Brannigan +10 more
20140 citations
Semantic Scholar
The role of the cGMP-dependent protein kinase in development of the malaria parasite
Louisa McRobert, Helen M. Taylor, Cathy J. Taylor, Wensheng Deng +8 more
2009BMC Pharmacology0 citations Open access
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Plasmodium falciparum cGMP-dependent protein kinase plays a central role in schizogony
Helen M. Taylor, Louisa McRobert, M. Grainger, A. Holder +1 more
20080 citations
Semantic Scholar
Systems biology and malaria
E. Winzeler, K. L. Le Roch, Ying-Yao Zhou, P. L. Blair +7 more
2004Annual International Conference on Research in Computational Molecular Biology0 citations
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