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L. McEwen · SciRah

Researcher profile · Semantic Scholar

L. McEwen

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L. McEwen — researcher profile on SciRah

h-index: 27
Works: 62
Citations: 2,552

Most-cited papers

The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes
A. Teh, Hong Pan, Li Chen, M. Ong +21 more
2014Genome Research328 citations Open access
Semantic Scholar
The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells
L. McEwen, K. O’Donnell, Megan G. McGill, Rachel D. Edgar +36 more
2019Proceedings of the National Academy of Sciences of the United States of America250 citations Open access
Semantic Scholar
Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array
L. McEwen, Meaghan J. Jones, David T. S. Lin, Rachel D. Edgar +9 more
2018Clinical Epigenetics137 citations Open access
Semantic Scholar
Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation
Rachel L. Clifford, Meaghan J. Jones, J. MacIsaac, L. McEwen +4 more
2017Journal of Allergy and Clinical Immunology122 citations Open access
Semantic Scholar
Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation
Lucas T. Husquin, M. Rotival, M. Fagny, H. Quach +7 more
2018Genome Biology117 citations Open access
Semantic Scholar
The biological embedding of early-life socioeconomic status and family adversity in children's genome-wide DNA methylation
Nicole R. Bush, Rachel D. Edgar, Mina Park, J. MacIsaac +5 more
2018Epigenomics106 citations Open access
Semantic Scholar
Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in down syndrome
Meaghan J. Jones, Pau Farré, L. McEwen, J. MacIsaac +6 more
2013BMC Medical Genomics93 citations Open access
Semantic Scholar
The epigenomic landscape of African rainforest hunter-gatherers and farmers
M. Fagny, E. Patin, J. MacIsaac, M. Rotival +16 more
2015Nature Communications85 citations Open access
Semantic Scholar
Early-life socioeconomic disadvantage, not current, predicts accelerated epigenetic aging of monocytes.
Makeda K Austin, E. Chen, K. Ross, L. McEwen +3 more
2018Psychoneuroendocrinology82 citations
Semantic Scholar
Trends in DNA Methylation with Age Replicate Across Diverse Human Populations
S. Gopalan, O. Carja, M. Fagny, E. Patin +8 more
2016Genetics82 citations Open access
Semantic Scholar
Natural variation in maternal care and cross-tissue patterns of oxytocin receptor gene methylation in rats
Annaliese K. Beery, L. McEwen, J. MacIsaac, D. Francis +1 more
2015Hormones and Behavior78 citations Open access
Semantic Scholar
Accelerated DNA methylation age in adolescent girls: associations with elevated diurnal cortisol and reduced hippocampal volume
E. Davis, K. Humphreys, L. McEwen, M. Sacchet +5 more
2017Translational Psychiatry77 citations Open access
Semantic Scholar
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes
Li Chen, Hong Pan, T. Tuan, A. Teh +17 more
2015Development and Psychopathology75 citations
Semantic Scholar
The early care environment and DNA methylome variation in childhood
Elika Garg, Li Chen, Thao T. T. Nguyen, I. Pokhvisneva +17 more
2018Development and Psychopathology71 citations Open access
Semantic Scholar
Maternal blood contamination of collected cord blood can be identified using DNA methylation at three CpGs
Alexander M. Morin, Evan Gatev, L. McEwen, J. MacIsaac +9 more
2017Clinical Epigenetics71 citations Open access
Semantic Scholar
Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults
Andres Cardenas, Simone Ecker, R. Fadadu, K. Huen +8 more
2022Scientific Reports68 citations Open access
Semantic Scholar
Epigenetic correlates of neonatal contact in humans
S. R. Moore, L. McEwen, J. Quirt, Alexander M. Morin +4 more
2017Development and Psychopathology66 citations
Semantic Scholar
A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regions
S. H. Hari Dass, K. McCracken, I. Pokhvisneva, Lawrence M. Chen +12 more
2019EBioMedicine64 citations Open access
Semantic Scholar
DNA methylation profiling in human Huntington's disease brain.
Rebecca A. G. De Souza, Sumaiya Islam, L. McEwen, Anthony Mathelier +5 more
2016Human Molecular Genetics60 citations
Semantic Scholar
Maternal Prenatal Anxiety and the Fetal Origins of Epigenetic Aging.
Megan G. McGill, I. Pokhvisneva, Andrew Clappison, L. McEwen +12 more
2021Biological Psychiatry58 citations Open access
Semantic Scholar
Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time
Marie Forest, K. O’Donnell, G. Voisin, H. Gaudreau +7 more
2018Epigenetics47 citations Open access
Semantic Scholar
Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD
Rachel L. Clifford, N. Fishbane, J. Patel, J. MacIsaac +7 more
2018Clinical Epigenetics39 citations Open access
Semantic Scholar
DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up
K. O’Donnell, Li Chen, J. MacIsaac, L. McEwen +14 more
2018Translational Psychiatry39 citations Open access
Semantic Scholar
Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region
L. McEwen, Alexander M. Morin, Rachel D. Edgar, J. MacIsaac +5 more
2017Epigenetics & Chromatin35 citations Open access
Semantic Scholar
A pooling-based approach to mapping genetic variants associated with DNA methylation
Irene M. Kaplow, J. MacIsaac, Sarah M. Mah, L. McEwen +2 more
2015bioRxiv33 citations Open access
Semantic Scholar
Exploring genetic influences underlying acute aerobic exercise effects on motor learning
Cameron S. Mang, L. McEwen, J. MacIsaac, N. J. Snow +4 more
2017Scientific Reports30 citations Open access
Semantic Scholar
PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores
Lawrence M. Chen, Nelson Yao, Elika Garg, Yuecai Zhu +13 more
2017BMC Bioinformatics28 citations Open access
Semantic Scholar
The relation between DNA methylation patterns and serum cytokine levels in community-dwelling adults: a preliminary study
C. Verschoor, L. McEwen, Vikas Kohli, C. Wolfson +4 more
2017BMC Genetics27 citations Open access
Semantic Scholar
Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy.
Chen-Xi Yang, Emma Schon, M. Obeidat, M. Kobor +14 more
2020Journal of Infectious Diseases26 citations Open access
Semantic Scholar
The relationship between the epigenetic aging biomarker “grimage” and lung function in both the airway and blood of people living with HIV: An observational cohort study
A. I. Hernández Cordero, Chen-Xi Yang, J. Yang, Xuan Li +46 more
2022EBioMedicine20 citations Open access
Semantic Scholar
DNA methylation is associated with airflow obstruction in patients living with HIV
A. I. Hernández Cordero, Chen-Xi Yang, M. Obeidat, J. Yang +12 more
2020Thorax20 citations Open access
Semantic Scholar
An integrated, modular approach to data science education in microbiology
K. A. Dill-McFarland, Stephan G. König, F. Mazel, David C. Oliver +3 more
2021PLoS Comput. Biol.17 citations Open access
Semantic Scholar
Maternal antenatal depression and child mental health: Moderation by genomic risk for attention-deficit/hyperactivity disorder
Lawrence M. Chen, M. Tollenaar, S. H. Hari Dass, A. Bouvette-Turcot +13 more
2020Development and Psychopathology15 citations Open access
Semantic Scholar
DNA methylation signatures in peripheral blood mononuclear cells from a lifestyle intervention for women at midlife: a pilot randomized controlled trial.
L. McEwen, Evan Gatev, Meaghan J. Jones, J. MacIsaac +6 more
2018Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme15 citations Open access
Semantic Scholar
Airway epithelial cell isolation techniques affect DNA methylation profiles with consequences for analysis of asthma related perturbations to DNA methylation
Rachel L. Clifford, J. Patel, J. MacIsaac, L. McEwen +5 more
2019Scientific Reports14 citations Open access
Semantic Scholar
Occurrence of Accelerated Epigenetic Aging and Methylation Disruptions in Human Immunodeficiency Virus Infection Before Antiretroviral Therapy
Xi Yang, Emma Schon, M. Obeidat, S. Kobor +14 more
202113 citations
Semantic Scholar
DNA methylation patterns are related to co‐morbidity status and circulating C‐reactive protein levels in the nursing home elderly
C. Verschoor, L. McEwen, M. Kobor, M. Loeb +1 more
2017Experimental Gerontology13 citations
Semantic Scholar
TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma
Rachel L. Clifford, Chen-Xi Yang, N. Fishbane, J. Patel +9 more
2020Clinical Epigenetics11 citations Open access
Semantic Scholar
DNA methylation pro ﬁ ling in human Huntington ’ s disease brain
Rebecca A. G. De Souza, Sumaiya Islam, L. McEwen, Anthony Mathelier +5 more
20169 citations
Semantic Scholar
The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing
L. McEwen, S. Goodman, M. Kobor, Meaghan J. Jones
20176 citations
Semantic Scholar
Population Genomic Screening and Improved Lipid Management in Patients With Familial Hypercholesterolemia
M. Levy, K. S. Schiabor Barrett, M. Betts, D. Kann +17 more
2025Circulation Genomic and Precision Medicine3 citations Open access
Semantic Scholar
An integrated, modular approach to data science education in the life sciences
K. A. Dill-McFarland, Stephan G. König, F. Mazel, David C. Oliver +3 more
2020bioRxiv3 citations Open access
Semantic Scholar
Intergenerational Transmission of Well Being–Genetic and Epigenetic Mechanisms
E. Unternaehrer, K. Greenlaw, S. H. Dass, L.-M. Chen +14 more
2017European psychiatry3 citations Open access
Semantic Scholar
Reply to: Crossing the "Birth Border" for Epigenetic Effects.
Megan G. McGill, I. Pokhvisneva, Andrew Clappison, L. McEwen +12 more
2022Biological Psychiatry2 citations Open access
Semantic Scholar
Maternal early life adversities and the offspring's epigenome: A M.A.V.A.N. project.
E. Unternaehrer, K. O’Donnell, A. Bouvette-Turcot, H. Gaudreau +12 more
2015Psychoneuroendocrinology2 citations
Semantic Scholar
Bidirectional effect of early adversity on epigenetic ageing in children: Mediation by C-reactive protein and moderation by FKBP5 gene and cortisol status
Felix Dammering, L. McEwen, N. Provençal, K. Punder +11 more
2019Psychoneuroendocrinology1 citations
Semantic Scholar
Exercise induces Skeletal Muscle Methylome and Transcriptome changes, regardless of Age and COPD
Poojitha Rajasekar, L. Latimer, L. Houchen-Wolloff, Kamini Rakkar +12 more
2026bioRxiv0 citations
Semantic Scholar
Genetic and environmental factors predict multivariate trajectories of maternal distress after birth
E. Unternaehrer, K. Greenlaw, A. Ciampi, Lawrence M. Chen +21 more
20210 citations Open access
Semantic Scholar
TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma
Rachel L. Clifford, Chen-Xi Yang, N. Fishbane, J. Patel +9 more
2020Clinical Epigenetics0 citations Open access
Semantic Scholar
Differential Methylation of TWIST1 Is a Biomarker of Airway Versus Parenchymal Fibroblasts Within the Lung: Relevance to Asthma Pathogenesis
Rachel L. Clifford, Xi-Yang Chen, N. Fishbane, J. Patel +8 more
20200 citations
Semantic Scholar

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M. Kobor×46
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J. MacIsaac×32
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M. Meaney×13
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K. O’Donnell×12
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Meaghan J. Jones×9

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Elika Garg — researcher profile on SciRah

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H. Gaudreau — researcher profile on SciRah

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Rachel L. Clifford — researcher profile on SciRah