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L. Lisowski · SciRah

Researcher profile · Semantic Scholar

L. Lisowski

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L. Lisowski — researcher profile on SciRah

h-index: 32
Works: 119
Citations: 3,863

Most-cited papers

Selection and evaluation of clinically relevant AAV variants in a xenograft liver model
L. Lisowski, Allison P. Dane, K. Chu, Yue Zhang +6 more
2013Nature436 citations Open access
Semantic Scholar
Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa
V. Sebastiano, H. Zhen, Bahareh Haddad, E. Bashkirova +18 more
2014Science Translational Medicine204 citations Open access
Semantic Scholar
Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Recapitulates Long QT Phenotype for Drug Testing
Yong-Ming Wang, Ping Liang, Feng Lan, Hao-Di Wu +9 more
2014Journal of the American College of Cardiology173 citations Open access
Semantic Scholar
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
N. Paulk, K. Pekrun, Erhua Zhu, Sean Nygaard +17 more
2018Molecular Therapy157 citations Open access
Semantic Scholar
The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis
Hiroki Kobayashi, Krystyna A. Gieniec, Josephine A. Wright, Tong-Tong Wang +32 more
2020Gastroenterology146 citations Open access
Semantic Scholar
Adeno-associated virus serotypes for gene therapeutics.
L. Lisowski, Szun S. Tay, I. Alexander
2015Current opinion in pharmacology (Print)141 citations
Semantic Scholar
In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation.
Ana M. Moreno, Xin Fu, Jie Zhu, Dhruva Katrekar +9 more
2018Molecular Therapy136 citations Open access
Semantic Scholar
An atypical parvovirus driving chronic tubulointerstitial nephropathy and kidney fibrosis
B. Roediger, Q. Lee, Shweta Tikoo, J. Cobbin +26 more
2018Cell102 citations Open access
Semantic Scholar
Optogenetic approaches to vision restoration
M. Simunovic, Wei-Yong Shen, John Y. Lin, D. Protti +2 more
2019Experimental Eye Research101 citations Open access
Semantic Scholar
Identification of liver-specific enhancer–promoter activity in the 3′ untranslated region of the wild-type AAV2 genome
G. Logan, Allison P. Dane, C. Hallwirth, C. Smyth +13 more
2017Nature Genetics95 citations
Semantic Scholar
Genome Editing of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells With Zinc Finger Nuclease for Cellular Imaging
Yong-Ming Wang, Wendy Y. Zhang, Shi-Jun Hu, Feng Lan +12 more
2012Circulation Research95 citations Open access
Semantic Scholar
High-Throughput In Vitro, Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction
Adrian Westhaus, Marti Cabanes-Creus, Arkadiusz Rybicki, Grober Baltazar +16 more
2020Human Gene Therapy92 citations Open access
Semantic Scholar
Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity
I. Winters, S. Chiou, N. Paulk, Christopher D. McFarland +7 more
2017Nature Communications88 citations Open access
Semantic Scholar
Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function.
Ronnie Blazev, Christian S. Carl, Yaan-Kit Ng, J. Molendijk +22 more
2022Cell Metabolism81 citations Open access
Semantic Scholar
Age-Related Seroprevalence of Antibodies Against AAV-LK03 in a UK Population Cohort
D. Perocheau, S. Cunningham, Juhee Lee, Juan Antinao Diaz +8 more
2019Human Gene Therapy72 citations Open access
Semantic Scholar
Somatic Correction of Junctional Epidermolysis Bullosa by a Highly Recombinogenic AAV Variant
Sandra P. Melo, L. Lisowski, E. Bashkirova, H. Zhen +5 more
2014Molecular Therapy71 citations Open access
Semantic Scholar
Engineering domain-inlaid SaCas9 adenine base editors with reduced RNA off-targets and increased on-target DNA editing
Minh Thuan Nguyen Tran, M. K. N. Mohd Khalid, Qi Wang, Jacqueline Walker +5 more
2020Nature Communications66 citations Open access
Semantic Scholar
Long-term ex situ normothermic perfusion of human split livers for more than 1 week
Ngee-Soon Lau, M. Ly, Claude Dennis, Andrew Jacques +13 more
2023Nature Communications55 citations Open access
Semantic Scholar
Restoring the natural tropism of AAV2 vectors for human liver
Marti Cabanes-Creus, C. Hallwirth, Adrian Westhaus, B. H. Ng +15 more
2020Science Translational Medicine52 citations Open access
Semantic Scholar
A User's Guide to the Inverted Terminal Repeats of Adeno-Associated Virus
Patrick Wilmott, L. Lisowski, I. Alexander, G. Logan
2019Human Gene Therapy Methods46 citations
Semantic Scholar
AAV vectors containing rDNA homology display increased chromosomal integration and transgene persistence.
Zhongya Wang, L. Lisowski, Milton J. Finegold, H. Nakai +2 more
2012Molecular Therapy42 citations Open access
Semantic Scholar
Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2
Marti Cabanes-Creus, Adrian Westhaus, R. G. Navarro, Grober Baltazar +15 more
2020Molecular Therapy: Methods & Clinical Development41 citations Open access
Semantic Scholar
Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8
Marti Cabanes-Creus, R. G. Navarro, Erhua Zhu, Grober Baltazar +11 more
2021Molecular Therapy: Methods & Clinical Development36 citations Open access
Semantic Scholar
Ribosomal DNA integrating rAAV-rDNA vectors allow for stable transgene expression.
L. Lisowski, Ashley Lau, Zhongya Wang, Yue Zhang +3 more
2012Molecular Therapy36 citations Open access
Semantic Scholar
Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys
J. Baruteau, S. Cunningham, B. Yilmaz, D. Perocheau +7 more
2021Molecular Therapy: Methods & Clinical Development33 citations Open access
Semantic Scholar
rAAV-mediated tumorigenesis: still unresolved after an AAV assault.
P. Valdmanis, L. Lisowski, M. Kay
2012Molecular Therapy33 citations Open access
Semantic Scholar
A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration
Rebecca San Gil, Dana S. Pascovici, Juliana Venturato, H. Brown-Wright +22 more
2024Nature Communications32 citations Open access
Semantic Scholar
Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality
Marti Cabanes-Creus, S. Ginn, A. Amaya, S. H. Liao +12 more
2018Molecular Therapy: Methods & Clinical Development32 citations Open access
Semantic Scholar
Liver splitting during normothermic machine perfusion: a novel method to combine the advantages of both in-situ and ex-vivo techniques.
Ngee-Soon Lau, M. Ly, Claude Dennis, K. Ewenson +11 more
2023HPB31 citations Open access
Semantic Scholar
Harnessing whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation
Marti Cabanes-Creus, S. H. Liao, Renina Gale Navarro, Maddison Knight +17 more
2024Nature Communications29 citations Open access
Semantic Scholar
A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization
Jin-Ying Chen, Fan-Li Lin, J. Leung, Leilei Tu +11 more
2020Angiogenesis29 citations Open access
Semantic Scholar
Neurological Disorders Associated with WWOX Germline Mutations—A Comprehensive Overview
Ehud Banne, Baraa Abudiab, Sara Abu-Swai, S. Repudi +7 more
2021Cells28 citations Open access
Semantic Scholar
In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation.
Ana M. Moreno, Xin Fu, Jie Zhu, Dhruva Katrekar +9 more
2020Molecular Therapy28 citations Open access
Semantic Scholar
Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes
S. Ginn, A. Amaya, S. H. Liao, Erhua Zhu +11 more
2019JHEP Reports28 citations Open access
Semantic Scholar
Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes
Cindy Y. Kok, Shinya Tsurusaki, Marti Cabanes-Creus, S. Igoor +17 more
2023Molecular Therapy: Methods & Clinical Development27 citations Open access
Semantic Scholar
Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids
Marti Cabanes-Creus, R. G. Navarro, S. H. Liao, Grober Baltazar +7 more
2021Molecular Therapy: Methods & Clinical Development27 citations Open access
Semantic Scholar
The self-peptide repertoire plays a critical role in transplant tolerance induction
Eric T. Son, P. Faridi, Moumita Paul-Heng, Mario Leong +11 more
2020bioRxiv27 citations Open access
Semantic Scholar
RNAi induced hepatotoxicity results from loss of the first synthesized isoform of miR-122 in mice
P. Valdmanis, Shuo Gu, K. Chu, Lan Jin +8 more
2016Nature Medicine26 citations Open access
Semantic Scholar
The future of recombinant host defense peptides
Ramon Roca-Pinilla, L. Lisowski, A. Arís, E. García-Fruitós
2022Microbial Cell Factories25 citations Open access
Semantic Scholar
AAV-p40 Bioengineering Platform for Variant Selection Based on Transgene Expression
Adrian Westhaus, Marti Cabanes-Creus, T. Jonker, Erwan Sallard +10 more
2022Human Gene Therapy25 citations Open access
Semantic Scholar
Enhanced AAV transduction across preclinical CNS models: A comparative study in human brain organoids with cross-species evaluations
Matthieu Drouyer, Jessica Merjane, Teodora Nedelkoska, Adrian Westhaus +11 more
2024Molecular Therapy: Nucleic Acids24 citations Open access
Semantic Scholar
Targeting Adeno-Associated Virus Vectors for Local Delivery to Fractures and Systemic Delivery to the Skeleton
Lucinda R. Lee, L. Peacock, L. Lisowski, D. Little +2 more
2019Molecular Therapy: Methods & Clinical Development24 citations Open access
Semantic Scholar
Impact of liver fibrosis on AAV-mediated gene transfer to mouse hepatocytes
R. Ferriero, Gemma Bruno, Agnese Padula, Simone Pisano +20 more
2025Nature Communications23 citations Open access
Semantic Scholar
A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs
Kieran English, Rain Y. Q. Kwan, Lauren E. Holz, Claire Mcguffog +9 more
2024Nature Communications21 citations Open access
Semantic Scholar
AAV capsid bioengineering in primary human retina models
Adrian Westhaus, S. Eamegdool, Milan Fernando, Paula I. Fuller-Carter +14 more
2023Scientific Reports21 citations Open access
Semantic Scholar
Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors
Adrian Westhaus, Marti Cabanes-Creus, Kimberley Dilworth, Erhua Zhu +23 more
2022bioRxiv20 citations Open access
Semantic Scholar
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
N. Meumann, Marti Cabanes-Creus, M. Ertelt, R. G. Navarro +22 more
2022Hepatology20 citations Open access
Semantic Scholar
The intersection of vector biology, gene therapy, and hemophilia
L. Lisowski, Janice M. Staber, J. F. Wright, L. Valentino
2021Research and Practice in Thrombosis and Haemostasis19 citations Open access
Semantic Scholar
Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle
N. Paulk, K. Pekrun, Gregory W. Charville, Katie K. Maguire-Nguyen +10 more
2018Molecular Therapy: Methods & Clinical Development19 citations Open access
Semantic Scholar
In Search of Adeno-Associated Virus Vectors With Enhanced Cardiac Tropism for Gene Therapy.
Natsuki Sasaki, Cindy Y. Kok, Adrian Westhaus, I. Alexander +2 more
2023Heart, Lung and Circulation18 citations Open access
Semantic Scholar

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I. Alexander — researcher profile on SciRah
Marti Cabanes-Creus×14
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Adrian Westhaus×12
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Adrian Westhaus — researcher profile on SciRah
Erhua Zhu×11
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M. Kay — researcher profile on SciRah

A. Thrasher×10

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