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P. Glazer · SciRah

Researcher profile · Semantic Scholar

P. Glazer

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P. Glazer — researcher profile on SciRah

h-index: 66
Works: 269
Citations: 15K

Most-cited papers

MicroRNA silencing for cancer therapy targeted to the tumor microenvironment
Christopher J. Cheng, R. Bahal, I. Babar, Zachary Pincus +8 more
2014Nature772 citations Open access
Semantic Scholar
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity
Parker L. Sulkowski, C. Corso, Nathaniel D. Robinson, Susan E. Scanlon +17 more
2017Science Translational Medicine499 citations Open access
Semantic Scholar
Oncometabolites suppress DNA repair by disrupting local chromatin signaling
Parker L. Sulkowski, S. Oeck, Jonathan Dow, Nicholas G. Economos +9 more
2020Nature265 citations Open access
Semantic Scholar
Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51
Alanna R. Kaplan, S. Gueble, Yan-Feng Liu, S. Oeck +3 more
2019Science Translational Medicine154 citations Open access
Semantic Scholar
Krebs Cycle-Deficient Hereditary Cancer Syndromes are Defined by Homologous Recombination DNA Repair Defects
Parker L. Sulkowski, R. Sundaram, S. Oeck, C. Corso +11 more
2018Nature Genetics152 citations Open access
Semantic Scholar
In utero nanoparticle delivery for site-specific genome editing
A. Ricciardi, Raman Bahal, James S. Farrelly, E. Quijano +12 more
2018Nature Communications149 citations Open access
Semantic Scholar
In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery
R. Bahal, Nicole Ali McNeer, E. Quijano, Yan-Feng Liu +18 more
2016Nature Communications144 citations Open access
Semantic Scholar
Mitochondrial DNA Stress Signalling Protects the Nuclear Genome
Zheng Wu, Sebastian Oeck, A. West, K. Mangalhara +12 more
2019Nature Metabolism135 citations Open access
Semantic Scholar
Multifaceted Control of DNA Repair Pathways by the Hypoxic Tumor Microenvironment
Susan E. Scanlon, P. Glazer
2015DNA Repair132 citations Open access
Semantic Scholar
Correction of F508del CFTR in airway epithelium using nanoparticles delivering triplex-forming PNAs
N. McNeer, Kavitha K. Anandalingam, R. J. Fields, Christina Caputo +10 more
2015Nature Communications125 citations Open access
Semantic Scholar
Suppressing miR-21 activity in tumor-associated macrophages promotes an antitumor immune response
M. Sahraei, B. Chaube, Yu-Ting Liu, Jonathan Sun +13 more
2019Journal of Clinical Investigation121 citations Open access
Semantic Scholar
The NIH Somatic Cell Genome Editing program
Krishanu Saha, E. Sontheimer, P. Brooks, M. Dwinell +71 more
2021Nature106 citations Open access
Semantic Scholar
The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells
Hoon Kim, Q. Lin, P. Glazer, Z. Yun
2018Breast Cancer Research105 citations Open access
Semantic Scholar
microRNAs in Cancer Cell Response to Ionizing Radiation
Jennifer R. Czochor, P. Glazer
2014Antioxidants and Redox Signaling93 citations Open access
Semantic Scholar
Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities
E. Quijano, R. Bahal, A. Ricciardi, W. M. Saltzman +1 more
2017The Yale Journal of Biology and Medicine82 citations
Semantic Scholar
Impact of hypoxia on DNA repair and genome integrity.
Alanna R. Kaplan, P. Glazer
2019Mutagenesis76 citations Open access
Semantic Scholar
Nanotechnology for Delivery of Peptide Nucleic Acids (PNA)
Anisha Gupta, R. Bahal, Meera Gupta, P. Glazer +1 more
2016Journal of Controlled Release68 citations Open access
Semantic Scholar
Targeting the Hypoxic and Acidic Tumor Microenvironment with pH-Sensitive Peptides
Nayanthara U. Dharmaratne, Alanna R. Kaplan, P. Glazer
2021Cells61 citations Open access
Semantic Scholar
Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing
A. Ricciardi, E. Quijano, R. Putman, W. Saltzman +1 more
2018Molecules59 citations Open access
Semantic Scholar
Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1
Yu-Hong Lu, Yan-Feng Liu, S. Oeck, P. Glazer
2018Molecular Cancer Research57 citations Open access
Semantic Scholar
Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorigenic lung cells
Susan E. Scanlon, Christine Scanlon, D. Hegan, Parker L. Sulkowski +1 more
2017Carcinogenesis51 citations Open access
Semantic Scholar
DNA-dependent targeting of cell nuclei by a lupus autoantibody
R. Weisbart, G. Chan, G. Jordaan, Philip W. Noble +4 more
2015Scientific Reports46 citations Open access
Semantic Scholar
miR-155 Over-expression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-prone DSB Repair
Jennifer R. Czochor, Parker L. Sulkowski, P. Glazer
2016Molecular Cancer Research43 citations Open access
Semantic Scholar
In vivo correction of cystic fibrosis mediated by PNA nanoparticles
Alexandra S. Piotrowski-Daspit, C. Barone, Chun-Yu Lin, Yan-Xiang Deng +12 more
2022bioRxiv42 citations Open access
Semantic Scholar
LINE-1 activation in the cerebellum drives ataxia
Takehiro Takahashi, M. Stoiljkovic, E. Song, Xiao-Bing Gao +15 more
2022Neuron40 citations Open access
Semantic Scholar
Hypoxic Stress Facilitates Acute Activation and Chronic Down-Regulation of Fanconi Anemia Proteins
Susan E. Scanlon, P. Glazer
2014Molecular Cancer Research39 citations Open access
Semantic Scholar
Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984
Joseph W. Kim, R. McKay, M. Radke, Shi-Lin Zhao +20 more
2022Journal of Clinical Oncology35 citations Open access
Semantic Scholar
Clinical Efficacy of Olaparib in IDH1/IDH2-Mutant Mesenchymal Sarcomas
J. Eder, D. Doroshow, K. Do, V. Keedy +4 more
2021JCO Precision Oncology34 citations Open access
Semantic Scholar
Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in VHL-deficient human renal cell carcinoma
Susan E. Scanlon, D. Hegan, Parker L. Sulkowski, P. Glazer
2017OncoTarget33 citations Open access
Semantic Scholar
Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity
Sophia Gayle, R. Aiello, N. Leelatian, J. Beckta +20 more
2021NAR Cancer30 citations Open access
Semantic Scholar
Tumor-Targeted, Cytoplasmic Delivery of Large, Polar Molecules using a pH-Low Insertion Peptide
Alexander A. Svoronos, R. Bahal, Mohan C. Pereira, F. Barrera +5 more
2019Molecular Pharmaceutics29 citations Open access
Semantic Scholar
In vivo correction of anaemia in beta-thalassemic mice by gammaPNA-mediated gene editing with nanoparticle delivery
R. Bahal, N. McNeer, E. Quijano, Yan-Feng Liu +18 more
201928 citations
Semantic Scholar
Nanoparticles for Delivery of Agents to Fetal Lungs
Sarah J. Ullrich, Mollie R. Freedman-Weiss, Samantha L. Ahle, Hanna K. Mandl +10 more
2021Acta Biomaterialia26 citations Open access
Semantic Scholar
BBIT20 inhibits homologous DNA repair with disruption of the BRCA1–BARD1 interaction in breast and ovarian cancer
L. Raimundo, Angela Paterna, J. Calheiros, J. Ribeiro +10 more
2021British Journal of Pharmacology25 citations Open access
Semantic Scholar
LKB1 preserves genome integrity by stimulating BRCA1 expression
Romi Gupta, Alex Y. Liu, P. Glazer, N. Wajapeyee
2014Nucleic Acids Research25 citations Open access
Semantic Scholar
PTEN Regulates Non-Homologous End Joining by Epigenetic Induction of NHEJ1/XLF
Parker L. Sulkowski, Susan E. Scanlon, S. Oeck, P. Glazer
2018Molecular Cancer Research22 citations Open access
Semantic Scholar
A cell-penetrating antibody inhibits human RAD51 via direct binding
Audrey Turchick, D. Hegan, R. B. Jensen, P. Glazer
2017Nucleic Acids Research22 citations Open access
Semantic Scholar
DNA polymerase beta germline variant confers cellular response to cisplatin therapy
Antonia A. Nemec, L. Abriola, J. Merkel, E. de Stanchina +4 more
2017Molecular Cancer Research22 citations Open access
Semantic Scholar
Synthetic lethality of a cell-penetrating anti-RAD51 antibody in PTEN-deficient melanoma and glioma cells
Audrey Turchick, Yan-Feng Liu, Weixi Zhao, Inessa Cohen +1 more
2019OncoTarget21 citations Open access
Semantic Scholar
YU238259 Is a Novel Inhibitor of Homology-dependent DNA Repair that Exhibits Synthetic Lethality and Radiosensitization in Repair-deficient Tumors
G. Stachelek, Elizabeth Peterson-Roth, Yan-Feng Liu, Rafael J Fernandez +7 more
2015Molecular Cancer Research20 citations Open access
Semantic Scholar
Electron-Mediated Aminyl and Iminyl Radicals from C5 Azido-Modified Pyrimidine Nucleosides Augment Radiation Damage to Cancer Cells
Zhiwei Wen, Jufang Peng, Paloma R Tuttle, Yaou Ren +13 more
2018Organic Letters19 citations Open access
Semantic Scholar
Tumor-targeted pH-low insertion peptide delivery of theranostic gadolinium nanoparticles for image-guided nanoparticle-enhanced radiation therapy
Wu Liu, J. Deacon, Hua-Gang Yan, Bo Sun +11 more
2020Translational Oncology17 citations Open access
Semantic Scholar
Ku80-targeted pH-sensitive peptide-PNA conjugates are tumor selective and sensitize cancer cells to ionizing radiation
Alanna R. Kaplan, H. Pham, Yan-Feng Liu, Stanley N Oyaghire +3 more
2020Molecular Cancer Research17 citations Open access
Semantic Scholar
Mechanism of Action Studies of Lomaiviticin A and the Monomeric Lomaiviticin Aglycon. Selective and Potent Activity Toward DNA Double-Strand Break Repair-Deficient Cell Lines
Laureen C. Colis, D. Hegan, M. Kaneko, P. Glazer +1 more
2015Journal of the American Chemical Society17 citations Open access
Semantic Scholar
Regulation of the Cell-Intrinsic DNA Damage Response by the Innate Immune Machinery
T. Hayman, P. Glazer
2021International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Clinical Activity and Safety of Cediranib and Olaparib Combination in Patients with Metastatic Pancreatic Ductal Adenocarcinoma without BRCA Mutation
Joseph W. Kim, D. Cardin, U. Vaishampayan, S. Kato +5 more
2021The Oncologist15 citations Open access
Semantic Scholar
Cooperation between oncogenic Ras and wild-type p53 stimulates STAT non-cell autonomously to promote tumor radioresistance
Yong-Li Dong, G. P. Vadla, J. Lu, V. Ahmad +5 more
2021Communications Biology15 citations Open access
Semantic Scholar
Poly(lactic-co-glycolic acid) Nanoparticle Delivery of Peptide Nucleic Acids In Vivo
Stanley N Oyaghire, E. Quijano, Alexandra S. Piotrowski-Daspit, W. M. Saltzman +1 more
2020Methods in molecular biology14 citations Open access
Semantic Scholar
Pathological Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma
Yang Xu, Paul Taylor, Joshua Andrade, B. Ueberheide +6 more
2018Cancer Research14 citations Open access
Semantic Scholar
DNA recognition and induced genome modification by a hydroxymethyl-γ tail-clamp peptide nucleic acid
Stanley N Oyaghire, E. Quijano, J. Perera, Hanna K. Mandl +3 more
2023bioRxiv13 citations Open access
Semantic Scholar

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Parker L. Sulkowski×8
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