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J. Wilkins · SciRah

Researcher profile · Semantic Scholar

J. Wilkins

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J. Wilkins — researcher profile on SciRah

h-index: 17
Works: 49
Citations: 1,275

Most-cited papers

Population Pharmacokinetics of Rifampin in Pulmonary Tuberculosis Patients, Including a Semimechanistic Model To Describe Variable Absorption
J. Wilkins, Radojka M. Savic, M. Karlsson, G. Langdon +4 more
2008Antimicrobial Agents and Chemotherapy168 citations Open access
Semantic Scholar
Population Pharmacokinetics and Pharmacodynamics of Paclitaxel and Carboplatin in Ovarian Cancer Patients: A Study by the European Organization for Research and Treatment of Cancer-Pharmacology and Molecular Mechanisms Group and New Drug Development Group
M. Joerger, A. Huitema, D. Richel, C. Dittrich +23 more
2007Clinical Cancer Research115 citations Open access
Semantic Scholar
Variability in the population pharmacokinetics of isoniazid in South African tuberculosis patients.
J. Wilkins, G. Langdon, H. McIlleron, G. Pillai +2 more
2011British Journal of Clinical Pharmacology112 citations Open access
Semantic Scholar
Effects of morphine and tramadol on somatic and visceral sensory function and gastrointestinal motility after abdominal surgery.
C. Wilder-Smith, L. Hill, J. Wilkins, L. Denny
1999Anesthesiology96 citations Open access
Semantic Scholar
Variability in the population pharmacokinetics of pyrazinamide in South African tuberculosis patients
J. Wilkins, G. Langdon, H. McIlleron, G. Pillai +2 more
2006European Journal of Clinical Pharmacology82 citations
Semantic Scholar
Time‐Varying Clearance and Impact of Disease State on the Pharmacokinetics of Avelumab in Merkel Cell Carcinoma and Urothelial Carcinoma
J. Wilkins, B. Brockhaus, H. Dai, Y. Vugmeyster +7 more
2019CPT: Pharmacometrics & Systems Pharmacology72 citations Open access
Semantic Scholar
Nonlinear Mixed‐Effects Model Development and Simulation Using nlmixr and Related R Open‐Source Packages
M. Fidler, J. Wilkins, R. Hooijmaijers, T. Post +4 more
2019CPT: Pharmacometrics & Systems Pharmacology70 citations Open access
Semantic Scholar
Population Pharmacokinetics of Ethambutol in South African Tuberculosis Patients
Siv Jönsson, Alistair Davidse, J. Wilkins, J. van der Walt +4 more
2011Antimicrobial Agents and Chemotherapy64 citations Open access
Semantic Scholar
NONMEMory: A run management tool for NONMEM
J. Wilkins
2005Comput. Methods Programs Biomed.48 citations
Semantic Scholar
Changing Body Weight–Based Dosing to a Flat Dose for Avelumab in Metastatic Merkel Cell and Advanced Urothelial Carcinoma
A. Novakovic, J. Wilkins, H. Dai, J. Wade +5 more
2019Clinical pharmacology and therapy44 citations Open access
Semantic Scholar
Open innovation: Towards sharing of data, models and workflows
D. Conrado, M. Karlsson, K. Romero, C. Sarr +1 more
2017European Journal of Pharmaceutical Sciences32 citations
Semantic Scholar
Safety, Tolerability, and Pharmacokinetics of Ribavirin in Hepatitis C Virus-Infected Patients with Various Degrees of Renal Impairment
B. Brennan, Ka Wang, S. Blotner, M. Magnusson +6 more
2013Antimicrobial Agents and Chemotherapy29 citations Open access
Semantic Scholar
Consecutive-dose pharmacokinetics of rifapentine in patients diagnosed with pulmonary tuberculosis.
G. Langdon, J. Wilkins, Peter C. Smith, H. McIlleron
2004The International Journal of Tuberculosis and Lung Disease27 citations
Semantic Scholar
Single-dose pharmacokinetics and tolerability of oral delta-9- tetrahydrocannabinol in patients with amyotrophic lateral sclerosis.
M. Joerger, J. Wilkins, S. Fagagnini, R. Baldinger +4 more
2012Drug Metabolism Letters25 citations
Semantic Scholar
Performance of the SAEM and FOCEI Algorithms in the Open‐Source, Nonlinear Mixed Effect Modeling Tool nlmixr
R. Schoemaker, M. Fidler, C. Laveille, J. Wilkins +5 more
2019CPT: Pharmacometrics & Systems Pharmacology22 citations Open access
Semantic Scholar
Population Pharmacokinetics of Rifapentine and Its Primary Desacetyl Metabolite in South African Tuberculosis Patients
G. Langdon, J. Wilkins, L. Mcfadyen, H. McIlleron +2 more
2005Antimicrobial Agents and Chemotherapy20 citations Open access
Semantic Scholar
Selection of the Recommended Phase 2 Dose for Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF‐β and PD‐L1
Y. Vugmeyster, J. Wilkins, A. Koenig, S. el Bawab +5 more
2020Clinical pharmacology and therapy19 citations Open access
Semantic Scholar
Training the next generation of pharmacometric modelers: a multisector perspective
P. Bonate, Jeffrey S. Barrett, Sihem Ait-Oudhia, R. Brundage +15 more
2023Journal of Pharmacokinetics and Pharmacodynamics17 citations Open access
Semantic Scholar
Pharmacometrics in tuberculosis: progress and opportunities.
J. Wilkins, E. Svensson, Jacqueline P. Ernest, R. Savic +2 more
2022International Journal of Antimicrobial Agents15 citations Open access
Semantic Scholar
Variability in the population pharmacokinetics of pyrazinamide in South African tuberculosis patients
J. Wilkins, G. Langdon, H. McIlleron, G. Pillai +2 more
2006European Journal of Clinical Pharmacology15 citations Open access
Semantic Scholar
Model-informed approach for risk management of bleeding toxicities for bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1
Y. Vugmeyster, Ana-Marija Grisic, J. Wilkins, A. Loos +4 more
2022Cancer Chemotherapy and Pharmacology14 citations Open access
Semantic Scholar
Population Pharmacokinetic Analysis of Bintrafusp Alfa in Different Cancer Types
J. Wilkins, Y. Vugmeyster, I. Dussault, P. Girard +1 more
2019Advances in Therapy14 citations
Semantic Scholar
Tools for Nonlinear Mixed-Effect Model Building and Diagnostics
A. Hooker, M. Karlsson, J. Wilkins, E. Jonsson
201414 citations
Semantic Scholar
A drug and disease model for lixisenatide, a GLP‐1 receptor agonist in type 2 diabetes
J. Wilkins, M. Dubar, Bernard Sebastien, C. Laveille
2014Journal of clinical pharmacology14 citations
Semantic Scholar
Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands.
J. L. van der Plas, Vincent P Kuiper, W. Bagchus, M. Bödding +21 more
2023Lancet. Infectious Diseases (Print)13 citations Open access
Semantic Scholar
Population Pharmacokinetics of Ipatasertib and Its Metabolite in Cancer Patients
Kenta Yoshida, J. Wilkins, J. Winkler, J. Wade +4 more
2021Journal of clinical pharmacology13 citations
Semantic Scholar
An economic comparison of chloroquine and sulfadoxine-pyrimethamine as first-line treatment for malaria in South Africa: development of a model for estimating recurrent direct costs.
J. Wilkins, Peter I. Folb, N. Valentine, Karen I. Barnes
2002Transactions of the Royal Society of Tropical Medicine and Hygiene12 citations
Semantic Scholar
Population Pharmacokinetics and Pharmacodynamics of the Calcimimetic Etelcalcetide in Chronic Kidney Disease and Secondary Hyperparathyroidism Receiving Hemodialysis
P. Chen, P. O. Gisleskog, J. Pérez-Ruixo, J. Xiao +4 more
2016CPT: Pharmacometrics & Systems Pharmacology11 citations Open access
Semantic Scholar
Evaluation of the nonparametric estimation method in nonmem VI: application to real data
P. Baverel, Radojka M. Savic, J. Wilkins, M. Karlsson
2009Journal of Pharmacokinetics and Pharmacodynamics10 citations Open access
Semantic Scholar
Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside
Akash Khandelwal, F. Arez, P. Alves, L. Badolo +10 more
2022Malaria Journal9 citations Open access
Semantic Scholar
Selection of the recommended phase 2 dose (RP2D) for M7824 (MSB0011359C), a bifunctional fusion protein targeting TGF-β and PD-L1.
Y. Vugmeyster, J. Wilkins, Eleanor Harrison-Moench, Wan-Ping Geng +5 more
20189 citations
Semantic Scholar
Thoughtflow: Standards and Tools for Provenance Capture and Workflow Definition to Support Model‐Informed Drug Discovery and Development
J. Wilkins, P. Chan, J. Chard, G. Smith +14 more
2017CPT: Pharmacometrics & Systems Pharmacology8 citations Open access
Semantic Scholar
Systemic pharmacokinetics of indacaterol, an inhaled once-daily long-acting beta2-agonist, in different ethnic populations.
Soichiro Matsushima, I. Matthews, R. Woessner, G. Pinault +3 more
2012International journal of clinical pharmacology and therapeutics8 citations
Semantic Scholar
Characterization of exposure–response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study
N. Kotani, J. Wilkins, J. Wade, Steve Dang +8 more
2022Cancer Chemotherapy and Pharmacology7 citations Open access
Semantic Scholar
R and nlmixr as a gateway between statistics and pharmacometrics
M. Fidler, R. Hooijmaijers, R. Schoemaker, J. Wilkins +2 more
2021CPT: Pharmacometrics & Systems Pharmacology6 citations Open access
Semantic Scholar
Data standards for model-informed drug development: an ISoP initiative
A. Radivojevic, B. Corrigan, N. Downie, R. Fox +11 more
2018Journal of Pharmacokinetics and Pharmacodynamics6 citations
Semantic Scholar
Modeling Disease Progression in Acute Stroke Using Clinical Assessment Scales
Kristin E. Karlsson, J. Wilkins, F. Jonsson, P. Zingmark +2 more
2010AAPS Journal5 citations Open access
Semantic Scholar
Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside
Akash Khandelwal, F. Arez, P. Alves, L. Badolo +10 more
2022Malaria Journal3 citations Open access
Semantic Scholar
Pharmacokinetics and Exposure-Efficacy Relationships of Omalizumab in Patients with Nasal Polyps.
Rui Zhu, R. Owen, J. Wilkins, R. Schoemaker +9 more
2021Pulmonary Pharmacology & Therapeutics3 citations Open access
Semantic Scholar
Evaluating the evaluations: resampling methods for determining model appropriateness in pharmacometric data analysis
L. Lindbom, J. Wilkins, N. Frey, M. Karlsson +1 more
20063 citations
Semantic Scholar
Bioequivalence, bootstrapping and case-deletion diagnostics in a biologic: a model-based analysis of the effect of formulation differences in a monoclonal antibody
J. Wilkins, A. Gautier, P. Lowe
20063 citations
Semantic Scholar
A cost analysis of the treatment of first-line uncomplicated malaria in the Tonga district of Mpumalanga
J. Wilkins
19992 citations
Semantic Scholar
A Randomised, Double-Blind, Placebo-Controlled Study Evaluating the Chemoprophylactic Activity of M5717 Against Plasmodium Falciparum in a Controlled Human Malaria Infection
J. L. van der Plas, Vincent P Kuiper, W. Bagchus, M. Bödding +21 more
2022Social Science Research Network1 citations
Semantic Scholar
The guard changes
J. Wilkins
2020Journal of Pharmacokinetics and Pharmacodynamics0 citations
Semantic Scholar
Diagnostics for Nonlinear Mixed-Effect Models [R package xpose4 version 4.7.0]
A. Hooker, M. Karlsson, J. Wilkins, E. Jonsson
20200 citations
Semantic Scholar
Pharmacometric and Pharmacokinetic Toolkit [R package pmxTools version 1.2.1]
J. Wilkins, Bill Denney, R. Schoemaker
20200 citations
Semantic Scholar
Nonlinear Mixed Effects Models in Population Pharmacokinetics and Pharmacodynamics [R package nlmixr version 1.1.1-9]
M. Fidler, Yuan Xiong, R. Schoemaker, J. Wilkins +3 more
20200 citations
Semantic Scholar
1093 POPULATION PHARMACOKINETIC (PK) ANALYSIS OF RIBAVIRIN (COPEGUS) IN CHRONIC HEPATITIS C (CHC) PATIENTS WITH CHRONIC KIDNEY DISEASE (CKD) LEADS TO CHANGES IN RECOMMENDED DOSING
B. Brennan, M. Magnusson, J. Wilkins, Paul L. Martin +3 more
20120 citations
Semantic Scholar
babelmixr2 and PopED: Quick Conversion of NONMEM, Monolix and nlmixr2/rxode2 Models to PopED Optimal Design Analysis
Matthew Fidler, William Denney, J. Harrold, R. Hooijmaijers +5 more
Proceedings of the American Conference of Pharmacometrics 20240 citations Open access
Semantic Scholar

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