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B. Tijms · SciRah

Researcher profile · Semantic Scholar

B. Tijms

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B. Tijms — researcher profile on SciRah

h-index: 47
Works: 359
Citations: 9,382

Most-cited papers

Cerebrospinal fluid proteomics in patients with Alzheimer’s disease reveals five molecular subtypes with distinct genetic risk profiles
B. Tijms, E. Vromen, O. Mjaavatten, H. Holstege +17 more
2024Nature Aging184 citations Open access
Semantic Scholar
The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging
Farhad B. Imam, R. Saloner, Jacob W. Vogel, V. Krish +48 more
2025Nature Medicine118 citations Open access
Semantic Scholar
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer’s disease
D. Western, J. Timsina, Li-Hua Wang, Ciyang Wang +36 more
2024Nature Genetics70 citations Open access
Semantic Scholar
Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseases
Muhammad Ali, Buddhiprabha Erabadda, Yi-Ke Chen, Ying Xu +14 more
2025Nature Medicine44 citations Open access
Semantic Scholar
APOE and immunity: Research highlights
Courtney M. Kloske, C. Barnum, André F. Batista, E. Bradshaw +36 more
2023Alzheimer's & Dementia30 citations Open access
Semantic Scholar
Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia
L. Lorenzini, A. Maranzano, Silvia Ingala, L. Collij +29 more
2024Neurology29 citations Open access
Semantic Scholar
Eigenvector centrality dynamics are related to Alzheimer’s disease pathological changes in non-demented individuals
L. Lorenzini, Silvia Ingala, L. Collij, V. Wottschel +17 more
2023Brain Communications29 citations Open access
Semantic Scholar
Involvement of the choroid plexus in Alzheimer’s disease pathophysiology: findings from mouse and human proteomic studies
Aurore Delvenne, Charysse Vandendriessche, J. Gobom, Marlies Burgelman +25 more
2024Fluids and Barriers of the CNS24 citations Open access
Semantic Scholar
Paired plasma lipidomics and proteomics analysis in the conversion from mild cognitive impairment to Alzheimer's disease
A. Gómez-Pascual, Talel Naccache, Jin Xu, K. Hooshmand +28 more
2024Comput. Biol. Medicine23 citations Open access
Semantic Scholar
Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN‐derived networks and highlights causal links in Alzheimer's disease
Liu Shi, Jin Xu, R. Green, A. Wretlind +22 more
2023Alzheimer's & Dementia23 citations Open access
Semantic Scholar
Depressive Symptoms and Amyloid Pathology.
Wietse A. Wiels, Julie E. Oomens, S. Engelborghs, C. Baeken +115 more
2025JAMA psychiatry22 citations Open access
Semantic Scholar
Discovery of novel CSF biomarkers to predict progression in dementia using machine learning
D. Gogishvili, Eleonora M. Vromen, Sascha J. Koppes-den Hertog, A. Lemstra +7 more
2023Scientific Reports22 citations Open access
Semantic Scholar
Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol
B. Padrela, Amnah Mahroo, Mervin Tee, M. Sneve +39 more
2024BMJ Open18 citations Open access
Semantic Scholar
Machine learning in Alzheimer’s disease genetics
M. Bracher-Smith, Federico Melograna, B. Ulm, C. Bellenguez +108 more
2025Nature Communications17 citations Open access
Semantic Scholar
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease
K. Nordengen, B. Kirsebom, G. Richter, L. Pålhaugen +18 more
2023Journal of Neuroinflammation14 citations Open access
Semantic Scholar
Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non‐demented individuals
L. Lorenzini, L. Collij, N. Tesi, N. Vilor-Tejedor +29 more
2024Alzheimer's & Dementia13 citations Open access
Semantic Scholar
Post‐GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3
D. Panyard, L. Reus, M. Ali, Jihua Liu +19 more
2024Alzheimer's & Dementia12 citations Open access
Semantic Scholar
Treatments for AD: towards the right target at the right time
W. M. van der Flier, B. Tijms
2023Nature Reviews Neurology11 citations Open access
Semantic Scholar
Genetically identical twin-pair difference models support the amyloid cascade hypothesis
E. Coomans, J. Tomassen, R. Ossenkoppele, B. Tijms +16 more
2023Brain : a journal of neurology9 citations Open access
Semantic Scholar
Genomic analyses reveal new insights into Alzheimer's disease
E. Uffelmann, D. Wightman, S. Bahrami, A. Shadrin +139 more
2025medRxiv7 citations
Semantic Scholar
A Machine Learning Model to Harmonize Volumetric Brain MRI Data for Quantitative Neuroradiological Assessment of Alzheimer Disease.
Damiano Archetti, V. Venkatraghavan, Béla Weiss, P. Bourgeat +10 more
2024Radiology: Artificial Intelligence7 citations Open access
Semantic Scholar
Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study
Julie E. Oomens, V. van Gils, S. Vos, W. Freeze +43 more
2025JAMA Network Open6 citations Open access
Semantic Scholar
CSF proteins of inflammation, proteolysis and lipid transport define preclinical AD and progression to AD dementia in cognitively unimpaired individuals
M. del Campo, Carlos Quesada, L. Vermunt, C. Peeters +8 more
2024Molecular Neurodegeneration6 citations Open access
Semantic Scholar
Cerebrospinal fluid markers link to synaptic plasticity responses and Alzheimer’s disease genetic pathways
B. Kirsebom, J. Nilsson, E. Vromen, Peter Mikael Arnesen +19 more
2025Molecular Neurodegeneration5 citations Open access
Semantic Scholar
Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer’s disease
Olav M. Andersen, M. D. de Waal, Giulia Monti, N. Tesi +102 more
2025Molecular Neurodegeneration5 citations Open access
Semantic Scholar
CSF proteomic profiles related to cognitive decline in MCI A+ depend on tau levels
Eleonora M. Vromen, D. D. de Leeuw, A. V. Van Harten, C. Teunissen +3 more
2025Brain : a journal of neurology5 citations Open access
Semantic Scholar
Connecting dementia risk loci to the CSF proteome identifies pathophysiological leads for dementia
L. Reus, I. Jansen, B. Tijms, P. Visser +18 more
2024Brain : a journal of neurology5 citations Open access
Semantic Scholar
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease
Aurore Delvenne, J. Gobom, S. Schindler, M. ten Kate +25 more
2024Alzheimer's & Dementia5 citations Open access
Semantic Scholar
Automated FreeSurfer segmentation and visual quality control in 10,000 MRI scans from a large memory clinic cohort
D. Bocancea, A. den Braber, Chen-Yang Jiang, E. Coomans +34 more
2023Alzheimer's & Dementia5 citations Open access
Semantic Scholar
Microglia protein profiles in CSF across Alzheimer’s disease clinical stages
Elena R. Blujdea, P. van Bokhoven, Pamela V. Martino-Adami, Victoria S. Marshe +47 more
2026Nature Aging4 citations Open access
Semantic Scholar
GWAS meta-analysis of CSF Alzheimer's disease biomarkers 18,948 individuals reveal novel loci and genes regulating lipid metabolism, brain volume and autophagy
C. Cruchaga, J. Timsina, Chenyang Jiang, Daniel L. McCartney +149 more
2025Research Square4 citations Open access
Semantic Scholar
Cerebrospinal fluid proteomic profiling of cognitively unimpaired individuals with suspected non-Alzheimer's disease pathophysiology
Aurore Delvenne, J. Gobom, L. Reus, V. Dobričić +21 more
2025Brain Communications4 citations Open access
Semantic Scholar
Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease
Eleonora M. Vromen, Senne B. Lageman, J. Gobom, R. van der Kant +23 more
2025Alzheimer's & Dementia4 citations Open access
Semantic Scholar
Musicality and social cognition in dementia: clinical and anatomical associations
J. J. van 't Hooft, W. L. Hartog, M. Braun, Dewi Boessen +14 more
2024Brain Communications4 citations Open access
Semantic Scholar
Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes
L. Reus, T. Boltz, Marcelo Francia, Merel Bot +11 more
2023bioRxiv4 citations Open access
Semantic Scholar
Epigenomic subtypes of late-onset Alzheimer’s disease reveal distinct microglial signatures
Valentin T. Laroche, Rachel Cavill, Morteza Kouhsar, Joshua Müller +15 more
2026Acta Neuropathologica3 citations Open access
Semantic Scholar
Cerebrospinal fluid proteome alterations related to depressive symptoms in cognitive decline and Alzheimer's disease
M. Rabl, W. L. Hartog, W. M. van der Flier, Y. Pijnenburg +14 more
2025Alzheimer's & Dementia3 citations Open access
Semantic Scholar
Cortical thickness subtypes in cognitively unimpaired individuals: Differential network and transcriptomic vulnerability to cortical thinning
L. Lorenzini, M. Tranfa, L. Pieperhoff, F. Masserini +34 more
2025Alzheimer's & Dementia3 citations Open access
Semantic Scholar
Immunoassay for pyruvate kinase M1/2 as an Alzheimer’s biomarker in CSF
Matthijs B. de Geus, P. Kivisäkk, Bianca A. Trombetta, B. Tijms +3 more
2025Open Life Sciences3 citations Open access
Semantic Scholar
Synaptic protein CSF levels relate to memory scores in individuals without dementia
K. Wesenhagen, D. D. de Leeuw, J. Tomassen, J. Gobom +20 more
2024Research Square3 citations Open access
Semantic Scholar
Axonal damage and inflammation response are biological correlates of decline in small-world values: a cohort study in autosomal dominant Alzheimer’s disease
L. Vermunt, C. Sutphen, E. Dicks, D. D. de Leeuw +34 more
2024Brain Communications3 citations Open access
Semantic Scholar
Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes
L. Reus, T. Boltz, Marcelo Francia, Merel Bot +11 more
2025Molecular Psychiatry2 citations Open access
Semantic Scholar
Epigenomic subtypes of late-onset Alzheimer’s disease reveal distinct microglial signatures
Valentin T. Laroche, Rachel Cavill, Morteza Kouhsar, R. Reijnders +14 more
2025bioRxiv2 citations Open access
Semantic Scholar
Synaptic protein CSF levels relate to memory scores in individuals without dementia
K. Wesenhagen, D. D. de Leeuw, J. Tomassen, J. Gobom +21 more
2025Alzheimer's Research & Therapy2 citations Open access
Semantic Scholar
Associations of lifestyle factors with amyloid pathology in persons without dementia
Julie E. Oomens, S. Vos, Nancy N. Maserejian, M. Boada +102 more
2025Journal of Alzheimer's Disease2 citations Open access
Semantic Scholar
A large-scale multi-centre study characterising atrophy heterogeneity in Alzheimer's disease
V. Venkatraghavan, Damiano Archetti, P. Bourgeat, Chen-Yang Jiang +20 more
2024medRxiv2 citations Open access
Semantic Scholar
Potential cost-effectiveness of individualized medicine in prodromal Alzheimer's disease by demographic, clinical and cerebrospinal fluid proteomics factors
R. Handels, K. Wesenhagen, B. Tijms, Charlotte E. Teunissen +2 more
2023medRxiv2 citations Open access
Semantic Scholar
Analytical framing of Amyloid beta monoclonal antibody trials in Alzheimer's disease can obscure clinical effects
B. Tijms, A. V. Van Harten, M. Carillo, P. Scheltens +1 more
2026Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk.
O. Quenez, Catherine Schramm, K. Cassinari, A. Nicolas +115 more
2026American Journal of Human Genetics1 citations Open access
Semantic Scholar
GWAS meta-analysis of cerebrospinal fluid Alzheimer’s biomarkers reveals loci regulating lipids, brain volume and autophagy
J. Timsina, Chen-Yang Jiang, Daniel L. McCartney, Feifei Tao +151 more
2026Nature Communications1 citations Open access
Semantic Scholar

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