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C. Barnum · SciRah

Researcher profile · Semantic Scholar

C. Barnum

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C. Barnum — researcher profile on SciRah

h-index: 26
Works: 56
Citations: 2,723

Most-cited papers

Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity
Vanesa Sánchez-Guajardo, C. Barnum, M. Tansey, M. Romero-Ramos
2013ASN Neuro231 citations Open access
Semantic Scholar
The involvement of norepinephrine and microglia in hypothalamic and splenic IL-1beta responses to stress.
P. Blandino, C. Barnum, T. Deak
2006Journal of Neuroimmunology180 citations
Semantic Scholar
Stress-induced increases in hypothalamic IL-1: a systematic analysis of multiple stressor paradigms.
T. Deak, Kelly A. Bordner, Nevin K McElderry, C. Barnum +3 more
2005Brain Research Bulletin150 citations
Semantic Scholar
Simultaneous imaging of locus coeruleus and substantia nigra with a quantitative neuromelanin MRI approach.
Xiang-Chuan Chen, D. Huddleston, J. Langley, Sinyeob Ahn +4 more
2014Magnetic Resonance Imaging142 citations
Semantic Scholar
Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress.
P. Blandino, C. Barnum, Lyvia G. Solomon, Yaniv Larish +2 more
2009Brain, behavior, and immunity136 citations
Semantic Scholar
The role of the dorsal raphe nucleus in the development, expression and treatment of LID in hemiparkinsonian rats
Karen L. Eskow, K. Dupre, C. Barnum, Sando O. Dickinson +2 more
2009Synapse130 citations Open access
Semantic Scholar
Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease.
A. Harms, C. Barnum, K. Ruhn, S. Varghese +3 more
2011Molecular Therapy118 citations Open access
Semantic Scholar
Targeting soluble tumor necrosis factor as a potential intervention to lower risk for late-onset Alzheimer’s disease associated with obesity, metabolic syndrome, and type 2 diabetes
Maria Elizabeth De Sousa Rodrigues, Madelyn C. Houser, D. Walker, Dean P. Jones +3 more
2019Alzheimer's Research & Therapy114 citations Open access
Semantic Scholar
Peripheral administration of the selective inhibitor of soluble Tumor Necrosis Factor (TNF) XPro®1595 attenuates nigral cell loss and glial activation in 6-OHDA hemiparkinsonian rats
C. Barnum, Xi Chen, Jaegwon Chung, Jianjun Chang +4 more
2014Journal of Parkinson's Disease109 citations Open access
Semantic Scholar
Psychological stress in adolescent and adult mice increases neuroinflammation and attenuates the response to LPS challenge
C. Barnum, T. Pace, Fang Hu, G. Neigh +1 more
2012Journal of Neuroinflammation107 citations Open access
Semantic Scholar
Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice
Maria Elizabeth De Sousa Rodrigues, M. Bekhbat, Madelyn C. Houser, Jianjun Chang +5 more
2016Brain, behavior, and immunity97 citations Open access
Semantic Scholar
Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease
Lori N. Eidson, G. Kannarkat, C. Barnum, Jianjun Chang +12 more
2017Journal of Neuroinflammation91 citations Open access
Semantic Scholar
Adaptation in the Corticosterone and Hyperthermic Responses to Stress Following Repeated Stressor Exposure
C. Barnum, Peter Blandino, Terrence Deak
2007Journal of neuroendocrinology87 citations
Semantic Scholar
Contribution of the Striatum to the Effects of 5-HT1A Receptor Stimulation in L-DOPA-treated Hemiparkinsonian Rats
C. Bishop, David M. Krolewski, Karen L. Eskow, C. Barnum +3 more
2009Journal of Neuroscience Research86 citations Open access
Semantic Scholar
Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia.
Maria Karamita, C. Barnum, Wiebke Möbius, M. Tansey +3 more
2017JCI Insight85 citations Open access
Semantic Scholar
Modeling neuroinflammatory pathogenesis of Parkinson's disease.
C. Barnum, M. Tansey
2010Progress in Brain Research85 citations
Semantic Scholar
Striatal 5-HT1A receptor stimulation reduces D1 receptor-induced dyskinesia and improves movement in the hemiparkinsonian rat
K. Dupre, Karen L. Eskow, C. Barnum, C. Bishop
2008Neuropharmacology85 citations Open access
Semantic Scholar
Neuroinflammation and Non-motor Symptoms: The Dark Passenger of Parkinson’s Disease?
C. Barnum, M. Tansey
2012Current Neurology and Neuroscience Reports82 citations
Semantic Scholar
A simple method for the efficient synthesis of unsaturated .beta.-dicarbonyl compounds
D. Liotta, C. Barnum, Robert Puleo, G. Zima +2 more
198162 citations
Semantic Scholar
Stress-dependent changes in neuroinflammatory markers observed after common laboratory stressors are not seen following acute social defeat of the Sprague Dawley rat.
C. Hueston, C. Barnum, Jaime A. Eberle, Frank J. Ferraioli +2 more
2011Physiology and Behavior61 citations
Semantic Scholar
Effects of noradrenergic denervation on L-DOPA-induced dyskinesia and its treatment by α- and β-adrenergic receptor antagonists in hemiparkinsonian rats
C. Barnum, N. Bhide, David Lindenbach, Margaret A. Surrena +5 more
2011Pharmacology, Biochemistry and Behavior53 citations Open access
Semantic Scholar
Behavioral and Cellular Modulation of l-DOPA-Induced Dyskinesia by β-Adrenoceptor Blockade in the 6-Hydroxydopamine-Lesioned Rat
David Lindenbach, Corinne Y. Ostock, K. L. Eskow Jaunarajs, K. Dupre +3 more
2011Journal of Pharmacology and Experimental Therapeutics51 citations Open access
Semantic Scholar
Microglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson’s disease: a case series
V. Joers, G. Masilamoni, Doty J. Kempf, A. Weiss +16 more
2020Neurobiology of Disease45 citations Open access
Semantic Scholar
Two weeks of predatory stress induces anxiety-like behavior with co-morbid depressive-like behavior in adult male mice
Jillybeth Burgado, C. S. Harrell, D. Eacret, Renuka Reddy +5 more
2014Behavioural Brain Research39 citations Open access
Semantic Scholar
Effects of the beta-adrenergic receptor antagonist Propranolol on dyskinesia and L-DOPA-induced striatal DA efflux in the hemi-parkinsonian rat
N. Bhide, David Lindenbach, C. Barnum, Jessica A. George +2 more
2015Journal of Neurochemistry33 citations Open access
Semantic Scholar
APOE and immunity: Research highlights
Courtney M. Kloske, C. Barnum, André F. Batista, E. Bradshaw +36 more
2023Alzheimer's & Dementia30 citations Open access
Semantic Scholar
Immune Influences on Behavior and Endocrine Activity in Early-Experience and Maternal Separation Paradigms
Michael B. Hennessy, T. Deak, P. A. Schiml-Webb, C. Barnum
200725 citations
Semantic Scholar
Diels-Alder reactions involving cross-conjugated dienones. Effects of substitution on reactivity
D. Liotta, M. Saindane, C. Barnum
198125 citations
Semantic Scholar
The impact of ventral noradrenergic bundle lesions on increased IL-1 in the PVN and hormonal responses to stress in male sprague dawley rats.
P. Blandino, C. Hueston, C. Barnum, C. Bishop +1 more
2013Endocrinology23 citations
Semantic Scholar
Photoelectron spectra of alkyl aryl selenides. Electronic and steric factors in the observation of rotamers
A. Baker, G. H. Armen, Guan-Ding Yang, D. Liotta +5 more
198122 citations
Semantic Scholar
Synthetic applications of 2-phenylselenenylenones—III
D. Liotta, M. Saindane, C. Barnum, G. Zima
198521 citations
Semantic Scholar
Chronic psychological stress during adolescence induces sex-dependent adulthood inflammation, increased adiposity, and abnormal behaviors that are ameliorated by selective inhibition of soluble tumor necrosis factor with XPro1595
Lori N. Eidson, Maria Elizabeth De Sousa Rodrigues, Michelle A. Johnson, C. Barnum +7 more
2019Brain, behavior, and immunity17 citations Open access
Semantic Scholar
Synthetic applications of 2-phenylselenenyl enones. Selective formation of exocyclic or endocyclic enones from a common intermediate
G. Zima, C. Barnum, D. Liotta
198017 citations
Semantic Scholar
Reactions involving selenium metal as an electrophile. The enolate - selenolate transformation
D. Liotta, G. Zima, C. Barnum, M. Saindane
198017 citations
Semantic Scholar
The duality of TNF signaling outcomes in the brain: Potential mechanisms?
C. Barnum, M. Tansey
2011Experimental Neurology16 citations
Semantic Scholar
Reactions involving selenium metal as an electrophile. 2. A general procedure for the preparation of unsaturated β-dicarbonyl compounds
D. Liotta, M. Saindane, C. Barnum, H. Ensley +1 more
198116 citations
Semantic Scholar
SELECTIVE REACTIONS OF CARBANIONS WITH P-QUINONES. THE AGGREGATE MODEL
D. Liotta, M. Saindane, C. Barnum
198114 citations
Semantic Scholar
Alzheimer’s disease research progress in Australia: The Alzheimer’s Association International Conference Satellite Symposium in Sydney
C. Sexton, K. Anstey, F. Baldacci, C. Barnum +31 more
2021Alzheimer's & Dementia8 citations Open access
Semantic Scholar
EXOGENOUS CORTICOSTERONE REDUCES L-DOPA-INDUCED DYSKINESIA IN THE HEMI-PARKINSONIAN RAT: ROLE FOR INTERLEUKIN-1β
C. Barnum, Karen L. Eskow, K. Dupre, P. Blandino +2 more
2008Neuroscience4 citations Open access
Semantic Scholar
Reactions involving selenium metal as an electrophile: Scope and limitations of the enolate‐selenolate transformation
K. Swiss, Woo-Baeg Choi, J. Mohan, C. Barnum +3 more
19904 citations
Semantic Scholar
Sexually dimorphic responses to MPTP found in microglia, inflammation and gut microbiota in a progressive monkey model of Parkinson’s disease
V. Joers, G. Masilamoni, Doty J. Kempf, A. Weiss +16 more
2020bioRxiv1 citations Open access
Semantic Scholar
Soluble TNF mediates high‐fat and high‐carbohydrate diet–induced inflammation, alterations in peripheral blood and brain immunophenotype, and gut microbiome in a mouse model of amyloid pathology
Mary K. Herrick, Kathryn P. Macpherson, Lori N. Eidson, Maria Elizabeth De Sousa Rodrigues +14 more
20201 citations Open access
Semantic Scholar
P4‐480: WESTERN DIET PROMOTES CENTRAL INSULIN IMPAIRMENT AND THE DYSREGULATION OF METABOLITES ASSOCIATED WITH ALZHEIMER'S DISEASE: THE ROLE OF SOLUBLE TNF
Maria Elizabeth de Sousa Rodrigues, Madelyn C. Houser, D. Walker, Dean P. Jones +3 more
2019Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Immunological Influences on Behavioral and Endocrine Responses during Early Development
Michael B. Hennessy, T. Deak, P. A. Schiml-Webb, C. Barnum
20071 citations
Semantic Scholar
Top‐line data from a phase 1b biomarker‐directed, proof of biology study in Alzheimer's patients treated with XPRO1595, a second‐generation treatment for immune dysfunction
R. Tesi, C. Barnum, M. Tansey
20200 citations Open access
Semantic Scholar
P4-662: PHASE 1B OPEN-LABEL, BIOMARKER-DIRECTED STUDY OF THE BRAIN PENETRANT, SOLUBLE SELECTIVE INHIBITOR OF SOLUBLE TUMOR NECROSIS FACTOR XPRO1595 IN PATIENTS WITH MILD TO MODERATE ALZHEIMER'S DISEASE
C. Barnum, M. Tansey, R. Tesi
2019Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Additional file 8: of Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease
Lori N. Eidson, G. Kannarkat, C. Barnum, Jianjun Chang +12 more
20170 citations
Semantic Scholar
Additional file 9: of Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease
Lori N. Eidson, G. Kannarkat, C. Barnum, Jianjun Chang +12 more
20170 citations
Semantic Scholar
Comparison of locus coeruleus volume between gradient echo and turbo spin echo sequences using a landmark-based segmentation scheme
J. Langley, D. Huddleston, Sinyeob Ahn, Xiang-Chuan Chen +2 more
20120 citations
Semantic Scholar
Do microglial glucocorticoid receptors protect against loss of dopaminergic neurons in Parkinson's disease?
C. Barnum, M. Tansey
20110 citations
Semantic Scholar

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