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T. Walle · SciRah

Researcher profile · Semantic Scholar

T. Walle

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T. Walle — researcher profile on SciRah

h-index: 68
Works: 267
Citations: 17K

Most-cited papers

HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS
T. Walle, Faye Hsieh, M. DeLegge, J. Oatis +1 more
2004Drug Metabolism And Disposition1,892 citations
Semantic Scholar
Bioavailability of resveratrol
T. Walle
2011Annals of the New York Academy of Sciences1,028 citations Open access
Semantic Scholar
Absorption and metabolism of flavonoids.
T. Walle
2004Free Radical Biology & Medicine615 citations
Semantic Scholar
What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol
O. Vang, N. Ahmad, C. Baile, Joseph A. Baur +17 more
2011PLoS ONE440 citations Open access
Semantic Scholar
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer
J. Chan, Á. Quintanal-Villalonga, Vianne R. Gao, Yu-Bin Xie +30 more
2021Cancer Cell385 citations Open access
Semantic Scholar
Methylated Flavonoids Have Greatly Improved Intestinal Absorption and Metabolic Stability
X. Wen, T. Walle
2006Drug Metabolism And Disposition385 citations
Semantic Scholar
Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma
S. Goswami, T. Walle, A. Cornish, S. Basu +16 more
2019Nature Medicine320 citations Open access
Semantic Scholar
Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?
T. Walle
2007Seminars in Cancer Biology292 citations Open access
Semantic Scholar
Flavonoid glucosides are hydrolyzed and thus activated in the oral cavity in humans.
T. Walle, Alyson M. Browning, L. Steed, S. G. Reed +1 more
2005Journal of NutriLife260 citations Open access
Semantic Scholar
Cellular Uptake and Efflux of the Tea Flavonoid (-)Epicatechin-3-gallate in the Human Intestinal Cell Line Caco-2
J. Vaidyanathan, T. Walle
2003Journal of Pharmacology and Experimental Therapeutics248 citations
Semantic Scholar
Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones.
T. Walle, Nga N Ta, T. Kawamori, X. Wen +2 more
2007Biochemical Pharmacology225 citations Open access
Semantic Scholar
Radiation effects on antitumor immune responses: current perspectives and challenges
T. Walle, R. Martínez-Monge, A. Cerwenka, D. Ajona +2 more
2018Therapeutic Advances in Medical Oncology219 citations Open access
Semantic Scholar
Resveratrol transport and metabolism by human intestinal Caco‐2 cells
Mark I. Kaldas, U. Walle, T. Walle
2003The Journal of pharmacy and pharmacology200 citations
Semantic Scholar
Methylation of dietary flavones greatly improves their hepatic metabolic stability and intestinal absorption.
T. Walle
2007Molecular Pharmaceutics191 citations
Semantic Scholar
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis
C. Burdziak, Direna Alonso-Curbelo, T. Walle, J. Reyes +21 more
2023Science186 citations Open access
Semantic Scholar
Intestinal epithelial cell accumulation of the cancer preventive polyphenol ellagic acid--extensive binding to protein and DNA.
A. Whitley, G. Stoner, M. Darby, T. Walle
2003Biochemical Pharmacology185 citations
Semantic Scholar
Methylation of Dietary Flavones Increases Their Metabolic Stability and Chemopreventive Effects
T. Walle
2009International Journal of Molecular Sciences153 citations Open access
Semantic Scholar
Evidence of covalent binding of the dietary flavonoid quercetin to DNA and protein in human intestinal and hepatic cells.
T. Walle, T. S. Vincent, U. Walle
2003Biochemical Pharmacology133 citations
Semantic Scholar
Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8
T. Walle, Joscha A. Kraske, Boyu Liao, B. Lenoir +28 more
2022Science Advances130 citations Open access
Semantic Scholar
Quercetin Induces Necrosis and Apoptosis in SCC-9 Oral Cancer Cells
M. Haghiac, T. Walle
2005Nutrition and Cancer106 citations
Semantic Scholar
Supervised discovery of interpretable gene programs from single-cell data
R. Kunes, T. Walle, Max Land, T. Nawy +1 more
2022bioRxiv93 citations Open access
Semantic Scholar
Methylation protects dietary flavonoids from rapid hepatic metabolism
X. Wen, T. Walle
2006Xenobiotica; the fate of foreign compounds in biological systems87 citations
Semantic Scholar
Covalent binding of the flavonoid quercetin to human serum albumin.
Mark I. Kaldas, U. Walle, H. van der Woude, J. McMillan +1 more
2005Journal of Agricultural and Food Chemistry86 citations Open access
Semantic Scholar
5,7-Dimethoxyflavone downregulates CYP1A1 expression and benzo[a]pyrene-induced DNA binding in Hep G2 cells.
X. Wen, U. Walle, T. Walle
2005Carcinogenesis85 citations Open access
Semantic Scholar
Preferential induction of CYP1B1 by benzo[a]pyrene in human oral epithelial cells: impact on DNA adduct formation and prevention by polyphenols.
X. Wen, T. Walle
2005Carcinogenesis77 citations Open access
Semantic Scholar
Cytotoxic effects of the dietary flavones chrysin and apigenin in a normal trout liver cell line.
P. Tsuji, T. Walle
2008Chemico-Biological Interactions76 citations Open access
Semantic Scholar
Induction of UDP-Glucuronosyl-Transferase by the Flavonoids Chrysin and Quercetin in Caco-2 Cells
A. Galijatovic, U. Walle, T. Walle
2004Pharmaceutical Research68 citations
Semantic Scholar
Flavonoid glycosides inhibit oral cancer cell proliferation — role of cellular uptake and hydrolysis to the aglycones
Alyson M. Browning, U. Walle, T. Walle
2005The Journal of pharmacy and pharmacology66 citations
Semantic Scholar
Bioavailable Flavonoids: Cytochrome P450-Mediated Metabolism of Methoxyflavones
U. Walle, T. Walle
2007Drug Metabolism And Disposition64 citations
Semantic Scholar
Tumor ENPP1(CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
Borja Ruiz-Fernández de Córdoba, Haritz Moreno, K. Valencia, N. Perurena +28 more
2022Cancer Discovery61 citations Open access
Semantic Scholar
BENZO[A]PYRENE-INDUCED ORAL CARCINOGENESIS AND CHEMOPREVENTION: STUDIES IN BIOENGINEERED HUMAN TISSUE
T. Walle, U. Walle, D. Sedmera, M. Klausner
2006Drug Metabolism And Disposition61 citations
Semantic Scholar
Formation of transient covalent protein and DNA adducts by quercetin in cells with and without oxidative enzyme activity.
H. van der Woude, G. Alink, B. V. van Rossum, K. Walle +3 more
2005Chemical Research in Toxicology60 citations Open access
Semantic Scholar
THE DIETARY POLYPHENOL ELLAGIC ACID IS A POTENT INHIBITOR OF hOAT1
A. Whitley, D. H. Sweet, T. Walle
2005Drug Metabolism And Disposition58 citations Open access
Semantic Scholar
Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids.
P. Tsuji, T. Walle
2005Carcinogenesis53 citations
Semantic Scholar
Accumulation and metabolism of the anticancer flavonoid 5,7-dimethoxyflavone compared to its unmethylated analog chrysin in the Atlantic killifish.
P. Tsuji, R. Winn, T. Walle
2006Chemico-Biological Interactions52 citations
Semantic Scholar
Aromatase inhibition by bioavailable methylated flavones.
Nga N Ta, T. Walle
2007Journal of Steroid Biochemistry and Molecular Biology47 citations Open access
Semantic Scholar
Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC‐9 human oral cancer cells
T. Walle, U. Walle
2007The Journal of pharmacy and pharmacology41 citations
Semantic Scholar
Impact of 68Ga-FAPI PET/CT on Staging and Oncologic Management in a Cohort of 226 Patients with Various Cancers
S. Koerber, M. Röhrich, L. Walkenbach, J. Liermann +12 more
2023Journal of Nuclear Medicine38 citations Open access
Semantic Scholar
Community-driven development of a modified progression-free survival ratio for precision oncology
A. Mock, C. Heilig, S. Kreutzfeldt, D. Huebschmann +101 more
2019ESMO Open36 citations Open access
Semantic Scholar
Improving metabolic stability of cancer chemoprotective polyphenols
T. Walle, X. Wen, U. Walle
2007Expert Opinion on Drug Metabolism & Toxicology36 citations
Semantic Scholar
Cytochrome P450 1B1, a novel chemopreventive target for benzo[a]pyrene-initiated human esophageal cancer.
X. Wen, T. Walle
2007Cancer Letters29 citations
Semantic Scholar
Benzo[a]pyrene-induced cytochrome P450 1A and DNA binding in cultured trout hepatocytes - inhibition by plant polyphenols.
P. Tsuji, T. Walle
2007Chemico-Biological Interactions28 citations Open access
Semantic Scholar
S‐adenosyl‐l‐methionine: transcellular transport and uptake by Caco‐2 cells and hepatocytes
J. M. McMillan, U. Walle, T. Walle
2005The Journal of pharmacy and pharmacology27 citations
Semantic Scholar
Completion rate and impact on physician–patient relationship of video consultations in medical oncology: a randomised controlled open-label trial
T. Walle, E. Erdal, Leon Mühlsteffen, Hans Martin Singh +19 more
2020ESMO Open26 citations Open access
Semantic Scholar
Stimulatory as well as inhibitory effects of ethinyloestradiol on the metabolic clearances of propranolol in young women.
T. Walle, T. Fagan, U. Walle, M. Topmiller
2003British Journal of Clinical Pharmacology26 citations Open access
Semantic Scholar
Site‐specific accumulation of the cancer preventive dietary polyphenol ellagic acid in epithelial cells of the aerodigestive tract
A. Whitley, D. H. Sweet, T. Walle
2006The Journal of pharmacy and pharmacology22 citations
Semantic Scholar
Negotiating their right to play: Asian-specific cricket teams and leagues in the UK and Norway
T. Fletcher, T. Walle
201521 citations Open access
Semantic Scholar
Cytokine release syndrome-like serum responses after COVID-19 vaccination are frequent and clinically inapparent under cancer immunotherapy
T. Walle, S. Bajaj, Joscha A. Kraske, T. Rösner +31 more
2022Nature Cancer20 citations Open access
Semantic Scholar
Berit Brandth og Elin Kvande: Fleksible fedre. Maskulinitet, arbeid, velferdsstat
T. Walle
200520 citations
Semantic Scholar
Electronic health intervention to manage symptoms of immunotherapy in patients with cancer (SOFIA): Results from a randomized controlled pilot trial
C. Sauer, S. Zschäbitz, Jürgen Krauss, T. Walle +6 more
2024Cancer16 citations Open access
Semantic Scholar

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