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M. Klausner · SciRah

Researcher profile · Semantic Scholar

M. Klausner

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M. Klausner — researcher profile on SciRah

h-index: 28
Works: 150
Citations: 2,017

Most-cited papers

Development of the EpiOcular™ Eye Irritation Test for Hazard Identification and Labelling of Eye Irritating Chemicals in Response to the Requirements of the EU Cosmetics Directive and REACH Legislation
Y. Kaluzhny, Helena Kandarova, P. Hayden, J. Kubilus +2 more
2011Alternatives to laboratory animals : ATLA78 citations Open access
Semantic Scholar
In Vitro Skin Irritation Testing: Improving the Sensitivity of the EpiDerm Skin Irritation Test Protocol
Helena Kandarova, P. Hayden, M. Klausner, J. Kubilus +2 more
2009Alternatives to laboratory animals : ATLA76 citations
Semantic Scholar
Human Primary Cell-Based Organotypic Microtissues for Modeling Small Intestinal Drug Absorption
S. Ayehunie, T. Landry, Zachary Stevens, A. Armento +2 more
2018Pharmaceutical Research70 citations Open access
Semantic Scholar
An in vitro skin irritation test (SIT) using the EpiDerm reconstructed human epidermal (RHE) model.
Helena Kandarova, P. Hayden, M. Klausner, J. Kubilus +1 more
2009Journal of Visualized Experiments69 citations Open access
Semantic Scholar
Intralaboratory and interlaboratory evaluation of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay.
Ting Hu, Y. Kaluzhny, G. Mun, B. Barnett +5 more
2009Mutation research62 citations
Semantic Scholar
Further development of the EpiDerm 3D reconstructed human skin micronucleus (RSMN) assay.
G. Mun, M. Aardema, Ting Hu, B. Barnett +5 more
2009Mutation research60 citations
Semantic Scholar
Prevalidation of an Acute Inhalation Toxicity Test Using the EpiAirway In Vitro Human Airway Model
G. Jackson, A. Maione, M. Klausner, P. Hayden
2018Applied In Vitro Toxicology59 citations Open access
Semantic Scholar
Development of an in vitro alternative assay method for vaginal irritation
S. Ayehunie, Chris Cannon, Karen Larosa, J. Pudney +2 more
2010Toxicology58 citations Open access
Semantic Scholar
In vitro three-dimensional organotypic culture models of the oral mucosa
M. Klausner, Y. Handa, S. Aizawa
2021In vitro Cellular & Developmental Biology-Animal54 citations Open access
Semantic Scholar
New Human Organotypic Corneal Tissue Model for Ophthalmic Drug Delivery Studies.
Y. Kaluzhny, M. Kinuthia, Thoa Truong, A. Lapointe +2 more
2018Investigative Ophthalmology and Visual Science54 citations Open access
Semantic Scholar
Human small intestinal organotypic culture model for drug permeation, inflammation, and toxicity assays
J. Markus, T. Landry, Zachary Stevens, Hailey Scott +5 more
2020In vitro Cellular & Developmental Biology-Animal45 citations Open access
Semantic Scholar
Characterization of a Hormone-Responsive Organotypic Human Vaginal Tissue Model
S. Ayehunie, Ayesha Islam, Chris Cannon, T. Landry +3 more
2015Reproductive Sciences45 citations Open access
Semantic Scholar
Microvesicating effects of sulfur mustard on an in vitro human skin model.
P. Hayden, J. Petrali, G. Stolper, T. Hamilton +5 more
2009Toxicology in Vitro40 citations
Semantic Scholar
Oxidative stress in corneal injuries of different origin: Utilization of 3D human corneal epithelial tissue model.
Y. Kaluzhny, M. Kinuthia, A. Lapointe, Thoa Truong +2 more
2019Experimental Eye Research39 citations Open access
Semantic Scholar
Application of MatTek In Vitro Reconstructed Human Skin Models for Safety, Efficacy Screening, and Basic Preclinical Research
P. Hayden, M. Bachelor, S. Ayehunie, S. Letašiová +3 more
201532 citations
Semantic Scholar
The EpiOcular Eye Irritation Test (EIT) for Hazard Identification and Labelling of Eye Irritating Chemicals: Protocol Optimisation for Solid Materials and the Results after Extended Shipment
Y. Kaluzhny, Helena Kandarova, Y. Handa, J. de Luca +5 more
2015Alternatives to laboratory animals : ATLA30 citations
Semantic Scholar
In vitro reconstructed 3D corneal tissue models for ocular toxicology and ophthalmic drug development
Y. Kaluzhny, M. Klausner
2021In vitro Cellular & Developmental Biology-Animal25 citations
Semantic Scholar
Gossypin as a Novel Selective Dual Inhibitor of v-raf Murine Sarcoma Viral Oncogene Homolog B1 and Cyclin-Dependent Kinase 4 for Melanoma
S. Bhaskaran, K. Dileep, S. S. Deepa, C. Sadasivan +5 more
2013Molecular Cancer Therapeutics23 citations Open access
Semantic Scholar
A plasmacytoid dendritic cell (CD123+/CD11c-) based assay system to predict contact allergenicity of chemicals
S. Ayehunie, M. Snell, M. Child, M. Klausner
2009Toxicology23 citations Open access
Semantic Scholar
Two- and Three-Dimensional Culture Systems: Respiratory In Vitro Tissue Models for Chemical Screening and Risk-Based Decision Making
Joanne Wallace, Mary McElroy, M. Klausner, Richard Corley +1 more
2025Pharmaceuticals16 citations Open access
Semantic Scholar
HIV Type 1 Fails to Trigger Innate Immune Factor Synthesis in Differentiated Oral Epithelium
W. Nittayananta, F. Hladik, M. Klausner, Socorro Harb +2 more
2009AIDS Research and Human Retroviruses11 citations Open access
Semantic Scholar
Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model
Y. Kaluzhny, Helena Kandarova, L. d’Argembeau-Thornton, P. Kearney +1 more
2015Journal of Visualized Experiments9 citations Open access
Semantic Scholar
Cancer Therapeutics Insights Tenovin-D 3 , a Novel Small-Molecule Inhibitor of Sirtuin SirT 2 , Increases p 21 ( CDKN 1 A ) Expression in a p 53-Independent Manner
Hiroyuki Monma, Nanae Harashima, Touko Inao, S. Okano +73 more
20139 citations
Semantic Scholar
Novel 3-D human small intestinal tissue model to assess drug permeation, inflammation, and wound healing
S. Ayehunie, Z. Stevens, T. Landry, M. Klausner +2 more
20147 citations
Semantic Scholar
Organotypic human oral tissue models for toxicological studies
Bridget Breyfogle, S. Letašiová, P. Hayden, M. Klausner
20136 citations
Semantic Scholar
Analysis of the validated epiderm skin corrosion test (EpiDerm SCT) and a prediction model for sub-categorization according to the UN GHS and EU CLP
Helena Kandarova, S. Letašiová, Y. Kaluzhny, P. Hayden +1 more
20135 citations
Semantic Scholar
A novel assay for evaluating wound healing in a full-thickness in vitro human skin model
K. Sebova, M. Bachelor, M. Klausner, P. Hayden +3 more
20154 citations
Semantic Scholar
Drug metabolizing enzyme activity of in vitro human dermal (EpiDerm™) and airway (EpiAirway™) epithelial models: Relationship to genotoxicity of chemicals as determined by in vitro skin micronucleus assays
Y. Kaluzhny, S. Letašiová, P. Hayden, J. Bolmarcich +2 more
20094 citations
Semantic Scholar
Novel 3D Human Small Intestinal Tissue Model (EpiIntestinal TM ) to Assess Drug Permeation & Inflammation
S. Ayehunie, Zachary Stevens, T. Landry, M. Taimi +2 more
20143 citations
Semantic Scholar
Key challenges for in vitro testing of oral tobacco and nicotine products for regulatory applications: Recommendations for using in vitro toxicity and disease models
E. Bishop, Katarina Aleksa, D. Breheny, Samuel Constant +17 more
2026Alternatives to laboratory animals : ATLA2 citations
Semantic Scholar
Development of an In Vitro Method for Assessing the Potential Irritation of Medical Devices and OTC Products Used in the Oral Cavity
C. Pellevoisin, Marek Puskar, J. Molignano, K. Coen +2 more
2025Toxics2 citations Open access
Semantic Scholar
Lab to lab reproducibility in the production of physiologically relevant reconstructed small intestine tissue for in vitro testing of toxicity, permeation and inflammation
J. Markus, T. Landry, M. Klausner, Helena Kandarova +3 more
20172 citations
Semantic Scholar
607 Measurement of skin pigmentation using a chromameter in a 3-dimensional epidermal model containing functional melanocytes
M. Bachelor, B. Breyfogle, A. Armento, M. Klausner
20162 citations Open access
Semantic Scholar
Predicting Organ Toxicity In Vitro
P. Hayden, M. Bachelor, M. Klausner, Helena Kandarova
20162 citations
Semantic Scholar
A new organotypic 3-D small intestinal tissue model reconstructed from primary human cells
S. Ayehunie, Zachary Stevens, T. Landry, A. Armento +2 more
20132 citations
Semantic Scholar
Optimization of the EpiOcular™ eye irritation test for hazard identification and labelling of chemicals in response to the requirements of the EU Cosmetic Directive and REACH Legislation
Y. Kaluzhny, Helena Kandarova, L. d’Argembeau-Thornton, J. de Luca +4 more
20132 citations
Semantic Scholar
Genotoxicity testing using the micronucleus and comet assays in normal human cell based 3D epithelia
Y. Kaluzhny, P. Hayden, Helena Kandarova, S. Letašiová +4 more
20112 citations
Semantic Scholar
523 T-cell cytokines (IL-17 and IFN-γ) exacerbates innate immune responses in an organotypic human psoriasis tissue model
S. Ayehunie, T. Landry, C. Hedin, A. Armento +2 more
2019Journal of Investigative Dermatology1 citations Open access
Semantic Scholar
New human organotypic corneal tissue model for ophthalmic drug delivery, dry eye, and wound healing studies
Y. Kaluzhny, M. Kinuthia, Thoa Truong, A. Lapointe +2 more
20181 citations
Semantic Scholar
Comparative inhalation toxicity testing using in vitro organotypic rat and human airway epithelial models
P. Hayden, G. Jackson, J. Vinall, E. Storey +5 more
2018Toxicology Letters1 citations
Semantic Scholar
Characterization of drug metabolizing enzymes, transporters and permeation in a human organotypic corneal tissue model
Y. Kaluzhny, M. Kinuthia, Thoa Truong, A. Lapointe +3 more
2018Toxicology Letters1 citations
Semantic Scholar
3D-human small intestinal tissue to study ligand-induced acute and chronic inflammation in the gastrointestinal tract
J. Markus, T. Landry, Zachary Stevens, M. Klausner +2 more
20171 citations
Semantic Scholar
3D-human small intestinal tissue model as an alternate to animal testing to predict drug toxicity, permeability, and metabolism
S. Ayehunie, Zachary Stevens, T. Landry, A. Armento +2 more
20171 citations
Semantic Scholar
357 Targeting the IL-17 – CCL20 pathway to screen drug candidates in an organotypic psoriasis tissue model
S. Ayehunie, T. Landry, Zachary Stevens, A. Armento +2 more
20161 citations Open access
Semantic Scholar
Organotypic in vitro human small intestinal tissue models to assess drug toxicity and permeation
S. Ayehunie, Zachary Stevens, T. Landry, M. Tami +2 more
20151 citations
Semantic Scholar
Development and optimization of the epiocular eye irritation test (EpiOcular EIT) for solid materials addressing the EU cosmetic legislation and reach
Y. Kaluzhny, Helena Kandarova, L. d’Argembeau-Thornton, J. de Luca +4 more
20141 citations
Semantic Scholar
Determination of airway genotoxicity potential using the EpiAirway in vitro human airway model and the comet assay
Helena Kandarova, A. Armento, J. de Luca, Y. Kaluzhny +2 more
20111 citations
Semantic Scholar
Cutaneous wound healing in the EpiDerm-FT full thickness in vitro human skin model
S. Letašiová, P. Hayden, G. Stolper, A. Armento +2 more
20101 citations
Semantic Scholar
Timecourse Of TH2 Cytokine-Induced Goblet Cell Hyperplasia In The EpiAirway In Vitro Human Airway Model
G. Jackson, Jennifer Bolmarcich, M. Klausner, P. Hayden
2010Asian Test Symposium1 citations
Semantic Scholar
Use of the organotypic EpiVaginal™ tissue model to screen irritation potential of feminine hygiene ingredients and formulations
Helena Kandarova, S. Ayehunie, Chris Cannon, Karen Larosa +2 more
20101 citations
Semantic Scholar

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