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A. Kaser · SciRah

Researcher profile · Semantic Scholar

A. Kaser

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A. Kaser — researcher profile on SciRah

h-index: 80
Works: 285
Citations: 24K

Most-cited papers

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
D. Klionsky, K. Abdelmohsen, A. Abe, M. Abedin +496 more
20161,544 citations Open access
Semantic Scholar
The unfolded protein response in immunity and inflammation
J. Grootjans, A. Kaser, R. Kaufman, R. Blumberg
2016Nature reviews. Immunology759 citations Open access
Semantic Scholar
Crohn’s disease
G. Roda, Siew Chien Ng, P. Kotze, M. Argollo +5 more
2020Nature Reviews Disease Primers724 citations
Semantic Scholar
Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study.
B. Feagan, W. Sandborn, G. D'Haens, J. Panés +18 more
2017The Lancet412 citations Open access
Semantic Scholar
Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
F. Sampaziotis, M. C. de Brito, Pedro Madrigal, A. Bertero +13 more
2015Nature Biotechnology372 citations Open access
Semantic Scholar
Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations.
A. Moschen, R. Gerner, Jun Wang, V. Klepsch +13 more
2016Cell Host and Microbe341 citations Open access
Semantic Scholar
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn’s disease
L. Mayr, F. Grabherr, J. Schwärzler, I. Reitmeier +29 more
2020Nature Communications247 citations Open access
Semantic Scholar
Long-term Efficacy of Vedolizumab for Ulcerative Colitis
E. Loftus, J. Colombel, B. Feagan, S. Vermeire +14 more
2016Journal of Crohn's & Colitis214 citations Open access
Semantic Scholar
Long-term Efficacy of Vedolizumab for Crohn’s Disease
S. Vermeire, E. Loftus, J. Colombel, B. Feagan +14 more
2016Journal of Crohn's & Colitis211 citations Open access
Semantic Scholar
Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis
Chenzhi Jing, Tomás Castro-Dopico, N. Richoz, Z. Tuong +14 more
2020Proceedings of the National Academy of Sciences of the United States of America178 citations Open access
Semantic Scholar
Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis
Markus Tschurtschenthaler, Timon E. Adolph, Jonathan W Ashcroft, L. Niederreiter +18 more
2017Journal of Experimental Medicine176 citations Open access
Semantic Scholar
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING
K. Aden, F. Tran, Go Ito, Raheleh Sheibani-Tezerji +22 more
2018Journal of Experimental Medicine159 citations Open access
Semantic Scholar
C13orf31 (FAMIN) is a central regulator of immunometabolic function
M. Z. Cader, Katharina Boroviak, Qi-Feng Zhang, G. Assadi +19 more
2016Nature Immunology150 citations Open access
Semantic Scholar
HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer
A. Teschendorff, Shih-Han Lee, Allison Jones, H. Fiegl +25 more
2015Genome Medicine144 citations Open access
Semantic Scholar
GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation
Tomás Castro-Dopico, Aaron Fleming, T. W. Dennison, J. Ferdinand +11 more
2020Cell Reports143 citations Open access
Semantic Scholar
Risankizumab in patients with moderate to severe Crohn's disease: an open-label extension study.
B. Feagan, J. Panés, M. Ferrante, A. Kaser +20 more
2018The Lancet Gastroenterology and Hepatology142 citations Open access
Semantic Scholar
Two microbiota subtypes identified in irritable bowel syndrome with distinct responses to the low FODMAP diet
K. Vervier, S. Moss, Nitin Kumar, Anne-Tounsia Adoum +12 more
2021Gut135 citations Open access
Semantic Scholar
Selecting Endpoints for Disease-Modification Trials in Inflammatory Bowel Disease: the SPIRIT consensus from the IOIBD.
C. Le Berre, L. Peyrin-Biroulet, W. Sandborn, J. Colombel +35 more
2021Gastroenterology128 citations Open access
Semantic Scholar
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells
N. Powell, Eirini Pantazi, P. Pavlidis, Anastasia Tsakmaki +18 more
2019Gut123 citations Open access
Semantic Scholar
Activating Transcription Factor 6 Mediates Inflammatory Signals in Intestinal Epithelial Cells Upon Endoplasmic Reticulum Stress
Stephanie T. Stengel, A. Fazio, S. Lipinski, M. Jahn +24 more
2020Gastroenterology122 citations Open access
Semantic Scholar
Epithelial calcineurin controls microbiota-dependent intestinal tumor development
K. Peuker, S. Muff, Jun Wang, Sven Künzel +21 more
2016Nature Medicine109 citations Open access
Semantic Scholar
Paneth Cell Alertness to Pathogens Maintained by Vitamin D Receptors
Rong Lu, Yong-Guo Zhang, Ying-Lin Xia, Jilei Zhang +3 more
2020Gastroenterology100 citations Open access
Semantic Scholar
Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation
K. Aden, A. Rehman, M. Falk-Paulsen, T. Sécher +21 more
2016Cell Reports98 citations Open access
Semantic Scholar
SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation
G. Bidault, S. Virtue, K. Petkevicius, H. Jolin +13 more
2021Nature Metabolism91 citations Open access
Semantic Scholar
GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump
G. Schneditz, Joshua E. Elias, E. Pagano, M. Z. Cader +10 more
2019Science Signaling86 citations Open access
Semantic Scholar
Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
J. Duan, J. D. Matute, L. Unger, T. Hanley +30 more
2023Immunity79 citations Open access
Semantic Scholar
FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle
M. Z. Cader, Rodrigo Pereira de Almeida Rodrigues, James A West, G. Sewell +18 more
2020Cell79 citations Open access
Semantic Scholar
Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease
S. Hosomi, A. Kaser, R. Blumberg
2015Current Opinion in Gastroenterology75 citations Open access
Semantic Scholar
PUFA-induced metabolic enteritis as a fuel for Crohn's disease.
J. Schwärzler, L. Mayr, A. V. Vila, F. Grabherr +29 more
2022Gastroenterology68 citations Open access
Semantic Scholar
Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment
E. Pagano, Joshua E. Elias, G. Schneditz, S. Saveljeva +5 more
2021Gut67 citations Open access
Semantic Scholar
Epithelial endoplasmic reticulum stress orchestrates a protective IgA response
J. Grootjans, N. Krupka, S. Hosomi, J. D. Matute +27 more
2019Science60 citations Open access
Semantic Scholar
Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation
S. Hosomi, J. Grootjans, Markus Tschurtschenthaler, N. Krupka +9 more
2017Journal of Experimental Medicine60 citations Open access
Semantic Scholar
Long-Term Safety and Efficacy of Risankizumab Treatment in Patients with Crohn’s Disease: Results from the Phase 2 Open-Label Extension Study
M. Ferrante, B. Feagan, J. Panés, F. Baert +11 more
2021Journal of Crohn's & Colitis55 citations Open access
Semantic Scholar
Author Correction: Crohn’s disease
G. Roda, S. Ng, P. Kotze, M. Argollo +5 more
2020Nature Reviews Disease Primers53 citations Open access
Semantic Scholar
Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptors
V. Wieser, T. Adolph, B. Enrich, A. Kuliopulos +3 more
2016Gut52 citations Open access
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
Semantic Scholar
A purine metabolic checkpoint that prevents autoimmunity and autoinflammation
S. Saveljeva, G. Sewell, K. Ramshorn, M. Z. Cader +17 more
2022Cell Metabolism47 citations Open access
Semantic Scholar
Interleukin-23 in the Pathogenesis of Inflammatory Bowel Disease and Implications for Therapeutic Intervention
G. Sewell, A. Kaser
2022Journal of Crohn's & Colitis47 citations Open access
Semantic Scholar
Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin
E. Melum, Xiao-Jun Jiang, K. Baker, M. F. Macedo +17 more
2019Nature Immunology47 citations Open access
Semantic Scholar
Trial summary and protocol for a phase II randomised placebo-controlled double-blinded trial of Interleukin 1 blockade in Acute Severe Colitis: the IASO trial
M. Thomas, Carrie Bayliss, S. Bond, F. Dowling +11 more
2019BMJ Open41 citations Open access
Semantic Scholar
Impaired Autophagy in CD11b+ Dendritic Cells Expands CD4+ Regulatory T Cells and Limits Atherosclerosis in Mice
M. Clément, J. Raffort, F. Lareyre, D. Tsiantoulas +12 more
2019Circulation Research39 citations Open access
Semantic Scholar
Intelectin-1 binds and alters the localization of the mucus barrier–modifying bacterium Akkermansia muciniphila
J. D. Matute, J. Duan, Magdalena B. Flak, Paul Griebel +27 more
2022Journal of Experimental Medicine36 citations Open access
Semantic Scholar
IDO1+ Paneth cells promote immune escape of colorectal cancer
Sandra Pflügler, J. Svinka, Irene Scharf, Ilija Crnčec +24 more
2020Communications Biology34 citations Open access
Semantic Scholar
New Insights Into the Regulation of Natural-Killer Group 2 Member D (NKG2D) and NKG2D-Ligands: Endoplasmic Reticulum Stress and CEA-Related Cell Adhesion Molecule 1
S. Hosomi, J. Grootjans, Yu‐Hwa Huang, A. Kaser +1 more
2018Frontiers in Immunology32 citations Open access
Semantic Scholar
A role for oncostatin M in inflammatory bowel disease
W. M. Kim, A. Kaser, R. Blumberg
2017Nature Medicine30 citations Open access
Semantic Scholar
CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation
S. Zeissig, K. Peuker, S. Iyer, Thomas Gensollen +4 more
2017Proceedings of the National Academy of Sciences of the United States of America29 citations Open access
Semantic Scholar
A HIF independent oxygen-sensitive pathway for controlling cholesterol synthesis
Anna S. Dickson, Tekle Pauzaite, Esther Arnaiz, Brian Ortmann +9 more
2023Nature Communications27 citations Open access
Semantic Scholar
Regulation of membrane fluidity by RNF145‐triggered degradation of the lipid hydrolase ADIPOR2
Norbert Volkmar, Christian M Gawden-Bone, J. Williamson, Jonathon Nixon-Abell +4 more
2022EMBO Journal26 citations Open access
Semantic Scholar
Epithelial XBP1 coordinates TP53-driven DNA damage responses and suppression of intestinal carcinogenesis
L. Welz, N. Kakavand, Xiang Hang, G. Laue +22 more
2021Gastroenterology25 citations Open access
Semantic Scholar
Genetic Risk of Severe Covid-19
A. Kaser
2020New England Journal of Medicine21 citations Open access
Semantic Scholar

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