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D. Jacobsen · SciRah

Researcher profile · Semantic Scholar

D. Jacobsen

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D. Jacobsen — researcher profile on SciRah

h-index: 43
Works: 154
Citations: 10K

Most-cited papers

Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis.
R. Clarke, R. Collins, S. Lewington, A. Donald +74 more
2002Journal of the American Medical Association (JAMA)1,947 citations
Semantic Scholar
Homocysteine and coronary atherosclerosis.
E. Mayer, D. Jacobsen, K. Robinson
1996Journal of the American College of Cardiology558 citations Open access
Semantic Scholar
Homocysteine and vitamins in cardiovascular disease.
D. Jacobsen
1998Clinical Chemistry447 citations
Semantic Scholar
Prospective study of hyperhomocysteinemia as an adverse cardiovascular risk factor in end-stage renal disease.
A. Moustapha, A. Naso, M. Nahlawi, Anjan Gupta +4 more
1998Circulation417 citations Open access
Semantic Scholar
Homocysteine Induces Expression and Secretion of Monocyte Chemoattractant Protein-1 and Interleukin-8 in Human Aortic Endothelial Cells: Implications for Vascular Disease
R. Poddar, N. Sivasubramanian, P. Dibello, K. Robinson +1 more
2001Circulation363 citations Open access
Semantic Scholar
Homocysteine in health and disease
R. Carmel, D. Jacobsen
2001355 citations Open access
Semantic Scholar
Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency
L. Hannibal, Vegard Lysne, Anne-Lise Bjørke-Monsen, S. Behringer +4 more
2016Frontiers in Molecular Biosciences338 citations Open access
Semantic Scholar
Homocysteine and its disulfide derivatives: a suggested consensus terminology.
S. Mudd, James D. Finkelstein, H. Refsum, P. Ueland +11 more
2000Arteriosclerosis, Thrombosis and Vascular Biology231 citations Open access
Semantic Scholar
TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia*
Gazi S. Hossain, J. V. van Thienen, G. Werstuck, Ji Zhou +11 more
2003Journal of Biological Chemistry211 citations Open access
Semantic Scholar
Albumin Thiolate Anion Is an Intermediate in the Formation of Albumin-S–S-Homocysteine*
S. Sengupta, Hong Chen, Tadayasu Togawa, P. Dibello +4 more
2001Journal of Biological Chemistry170 citations Open access
Semantic Scholar
Relative Roles of Albumin and Ceruloplasmin in the Formation of Homocystine, Homocysteine-Cysteine-mixed Disulfide, and Cystine in Circulation*
S. Sengupta, C. Wehbe, A. Majors, M. Ketterer +2 more
2001Journal of Biological Chemistry142 citations Open access
Semantic Scholar
Processing of alkylcobalamins in mammalian cells: a role for the MMACHC (cblC) gene product
L. Hannibal, Jihoe Kim, N. Brasch, Sihe Wang +3 more
2009Molecular Genetics and Metabolism136 citations Open access
Semantic Scholar
Normalization of Hyperhomocysteinemia with l-thyroxine in Hypothyroidism
W. Hussein, R. Green, D. Jacobsen, C. Faiman
1999Annals of Internal Medicine120 citations
Semantic Scholar
A Human Vitamin B12 Trafficking Protein Uses Glutathione Transferase Activity for Processing Alkylcobalamins*
Jihoe Kim, L. Hannibal, C. Gherasim, D. Jacobsen +1 more
2009Journal of Biological Chemistry118 citations Open access
Semantic Scholar
Homocysteine and lipoprotein(a) interact to increase CAD risk in young men and women.
J. Foody, J. Milberg, K. Robinson, G. Pearce +2 more
2000Arteriosclerosis, Thrombosis and Vascular Biology115 citations Open access
Semantic Scholar
Modulation of Cystathionine β-Synthase Level Regulates Total Serum Homocysteine in Mice
Li-Qun Wang, K. Jhee, X. Hua, P. Dibello +2 more
2004Circulation Research104 citations Open access
Semantic Scholar
Molecular Targeting of Proteins by L-Homocysteine: Mechanistic Implications for Vascular Disease
A. Glushchenko, D. Jacobsen
2007Antioxidants and Redox Signaling99 citations Open access
Semantic Scholar
Reduction of homocysteine levels in coronary artery disease by low-dose folic acid combined with vitamins B6 and B12.
A. Lobo, A. Naso, K. Arheart, W. Kruger +8 more
1999American Journal of Cardiology98 citations
Semantic Scholar
Homocysteine Binds to Human Plasma Fibronectin and Inhibits Its Interaction With Fibrin
A. Majors, S. Sengupta, B. Willard, M. Kinter +2 more
2002Arteriosclerosis, Thrombosis and Vascular Biology93 citations Open access
Semantic Scholar
Ethanol-induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes
Hui Tang, Becky M. Sebastian, A. Axhemi, Xiao-Cong Chen +3 more
2011Alcoholism: Clinical and Experimental Research87 citations Open access
Semantic Scholar
In Vitro and in Vivo Interactions of Homocysteine with Human Plasma Transthyretin*
A. Lim, S. Sengupta, M. Mccomb, R. Théberge +3 more
2003Journal of Biological Chemistry82 citations Open access
Semantic Scholar
Targeting of Metallothionein by L-Homocysteine: A Novel Mechanism for Disruption of Zinc and Redox Homeostasis
J. Barbato, O. Cătănescu, Kelsey Murray, P. Dibello +1 more
2007Arteriosclerosis, Thrombosis and Vascular Biology72 citations Open access
Semantic Scholar
Unexpected inverse relationship between insulin resistance and serum homocysteine in healthy subjects.
H. Rosolová, J. Šimon, O. Mayer, J. Racek +2 more
2002Physiological Research70 citations
Semantic Scholar
Both Selenium Deficiency and Modest Selenium Supplementation Lead to Myocardial Fibrosis in Mice via Effects on Redox-Methylation Balance
Nicole Metes-Kosik, I. Luptak, P. Dibello, D. Handy +6 more
2012Molecular Nutrition & Food Research69 citations Open access
Semantic Scholar
Plasma total homocysteine levels, dietary vitamin B6 and folate intake in AD and healthy aging.
E. Mizrahi, D. Jacobsen, S. Debanne, Fatoumata Traore +3 more
2003The Journal of Nutrition, Health & Aging69 citations
Semantic Scholar
Molecular targeting by homocysteine: a mechanism for vascular pathogenesis
D. Jacobsen, O. Cătănescu, P. Dibello, J. Barbato
2005Clinical Chemistry and Laboratory Medicine66 citations
Semantic Scholar
Acquired hyperhomocysteinemia in heart transplant recipients.
D. Jacobsen
1998Clinical Chemistry64 citations Open access
Semantic Scholar
Accurate assessment and identification of naturally occurring cellular cobalamins
L. Hannibal, A. Axhemi, A. Glushchenko, E. S. Moreira +2 more
2008Clinical Chemistry and Laboratory Medicine52 citations Open access
Semantic Scholar
A simple, convenient method to synthesize cobalamins: synthesis of homocysteinylcobalamin, N-acetylcysteinylcobalamin, 2-N-acetylamino-2-carbomethoxyethanethiolatocobalamin, sulfitocobalamin and nitrocobalamin.
E. Suarez-Moreira, L. Hannibal, Clyde A. Smith, Roberto A. Chavez +2 more
2006Dalton Transactions50 citations Open access
Semantic Scholar
Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice
Ji Zhou, G. Werstuck, S. Lhoták, Yuan Y. Shi +7 more
2008The FASEB Journal49 citations Open access
Semantic Scholar
The C-terminal domain of CblD interacts with CblC and influences intracellular cobalamin partitioning
C. Gherasim, L. Hannibal, Deepa Rajagopalan, D. Jacobsen +1 more
2013Biochimie46 citations Open access
Semantic Scholar
THE MMACHC PROTEOME: HALLMARKS OF FUNCTIONAL COBALAMIN DEFICIENCY IN HUMANS
L. Hannibal, P. Dibello, Michelle Yu, A. Miller +4 more
2011Molecular Genetics and Metabolism43 citations Open access
Semantic Scholar
COMPARISON OF THE DEOXYURIDINE SUPPRESSION TEST WITH SERUM LEVELS OF METHYLMALONIC ACID AND HOMOCYSTEINE IN MILD COBALAMIN DEFICIENCY
R. Carmel, K. Rasmussen, D. Jacobsen, R. Green
1996British Journal of Haematology42 citations
Semantic Scholar
Plasma homocysteine, vitamin B12 and folate in Alzheimer's patients and healthy Arabs in Israel.
E. Mizrahi, A. Bowirrat, D. Jacobsen, A. D. Korczyn +7 more
2004Journal of Neurological Sciences41 citations
Semantic Scholar
Targeted Metabolic Profiling of Methionine Cycle Metabolites and Redox Thiol Pools in Mammalian Plasma, Cells and Urine
S. Behringer, Victoria Wingert, V. Oria, A. Schumann +9 more
2019Metabolites40 citations Open access
Semantic Scholar
Homocysteine transport by systems L, A and y+L across the microvillous plasma membrane of human placenta
E. Tsitsiou, C. P. Sibley, Stephen W. D'Souza, O. Cătănescu +2 more
2009Journal of Physiology40 citations Open access
Semantic Scholar
Nitroxylcob(III)alamin: synthesis and X-ray structural characterization.
L. Hannibal, Clyde A. Smith, D. Jacobsen, N. Brasch
2007Angewandte Chemie40 citations Open access
Semantic Scholar
Homocysteine is transported by the microvillous plasma membrane of human placenta
E. Tsitsiou, C. Sibley, S. D'Souza, O. Cătănescu +2 more
2010Journal of Inherited Metabolic Disease37 citations Open access
Semantic Scholar
Upregulation of smooth muscle cell collagen production by homocysteine-insight into the pathogenesis of homocystinuria.
A. Majors, S. Sengupta, D. Jacobsen, R. Pyeritz
2002Molecular Genetics and Metabolism37 citations
Semantic Scholar
Neutrophil nuclear segmentation in mild cobalamin deficiency: relation to metabolic tests of cobalamin status and observations on ethnic differences in neutrophil segmentation.
R. Carmel, R. Green, D. Jacobsen, George D. Qian
1996American Journal of Clinical Pathology37 citations Open access
Semantic Scholar
Homocysteine transport by human aortic endothelial cells: identification and properties of import systems.
Beatrix Büdy, R. O'Neill, P. Dibello, S. Sengupta +1 more
2006Archives of Biochemistry and Biophysics36 citations Open access
Semantic Scholar
Mechanistic Studies on the Reaction between R2N-NONOates and Aquacobalamin: Evidence for Direct Transfer of a Nitroxyl Group from R2N-NONOates to Cobalt(III) Centers
Hanaa A. Hassanin, L. Hannibal, D. Jacobsen, M. Elshahat +2 more
2009Angewandte Chemie33 citations Open access
Semantic Scholar
Determinants of hyperhomocysteinemia: a matter of nature and nurture.
D. Jacobsen
1996American Journal of Clinical Nutrition33 citations Open access
Semantic Scholar
Hyperhomocysteinemia leads to exacerbation of ischemic brain damage: role of GluN2A NMDA receptors
A. Jindal, Sathyanarayanan Rajagopal, Lucas Winter, Joshua W. Miller +5 more
2019Neurobiology of Disease32 citations Open access
Semantic Scholar
Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs
M. Guzzo, Hoa T. Nguyen, T. H. Pham, Monika Wyszczelska-Rokiel +11 more
2016PLoS Pathogens32 citations Open access
Semantic Scholar
Association between hyperhomocysteinemia and primary pulmonary hypertension.
A. Arroliga, S. Sandur, D. Jacobsen, S. Tewari +3 more
2003Respiratory Medicine31 citations Open access
Semantic Scholar
Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores*
Ali A. Al-Hashimi, J. Caldwell, M. Gonzalez-Gronow, S. Pizzo +10 more
2010Journal of Biological Chemistry29 citations Open access
Semantic Scholar
The X-ray Crystal Structure of Glutathionylcobalamin Revealed
L. Hannibal, Clyde A. Smith, D. Jacobsen
2010Inorganic Chemistry28 citations Open access
Semantic Scholar
Proteomics of vitamin B12 processing
L. Hannibal, P. Dibello, D. Jacobsen
2013Clinical Chemistry and Laboratory Medicine27 citations Open access
Semantic Scholar
Homocysteine: update on a new risk factor.
R. Ballal, D. Jacobsen, K. Robinson
1997Cleveland Clinic journal of medicine26 citations
Semantic Scholar

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S. Sengupta×6
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N. Brasch — researcher profile on SciRah

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R. Poddar — researcher profile on SciRah

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R. Carmel — researcher profile on SciRah

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Clyde A. Smith — researcher profile on SciRah