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S. Lhoták · SciRah

Researcher profile · Semantic Scholar

S. Lhoták

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S. Lhoták — researcher profile on SciRah

h-index: 30
Works: 60
Citations: 3,429

Most-cited papers

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis
Stephen L. Pinkosky, R. Newton, Emily A. Day, R. Ford +8 more
2016Nature Communications440 citations Open access
Semantic Scholar
Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis
Sarathi Mani, Hong-Zhu Li, A. Untereiner, Ling-Yun Wu +6 more
2013Circulation372 citations Open access
Semantic Scholar
Activation of the Unfolded Protein Response Occurs at All Stages of Atherosclerotic Lesion Development in Apolipoprotein E–Deficient Mice
Ji Zhou, S. Lhoták, Brooke A. Hilditch, R. Austin
2005Circulation308 citations Open access
Semantic Scholar
The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response[S]
Sana Basseri, S. Lhoták, Arya M. Sharma, R. Austin
2009Journal of Lipid Research226 citations Open access
Semantic Scholar
Peroxynitrite Causes Endoplasmic Reticulum Stress and Apoptosis in Human Vascular Endothelium: Implications in Atherogenesis
J. Dickhout, Gazi S. Hossain, L. Pozza, Ji Zhou +2 more
2005Arteriosclerosis, Thrombosis and Vascular Biology214 citations
Semantic Scholar
Association of Multiple Cellular Stress Pathways With Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-Deficient Mice
Ji Zhou, G. Werstuck, S. Lhoták, A. B. L. de Koning +8 more
2004Circulation170 citations Open access
Semantic Scholar
Doxycycline decreases tumor burden in a bone metastasis model of human breast cancer.
W. Duivenvoorden, S. Popovic, S. Lhoták, E. Seidlitz +3 more
2002Cancer Research129 citations
Semantic Scholar
Mouse models of cystathionine β‐synthase deficiency reveal significant threshold effects of hyperhomocysteinemia
Sapna Gupta, Jirko Kühnisch, Ala Mustafa, S. Lhoták +6 more
2009The FASEB Journal116 citations Open access
Semantic Scholar
GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin‐induced pulmonary fibrosis
Ehab A. Ayaub, P. Kolb, Z. Mohammed-Ali, V. Tat +13 more
2016Journal of Pathology109 citations
Semantic Scholar
Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice
P. Lebeau, J. Byun, Khrystyna Platko, Ali A. Al-Hashimi +9 more
2019JHEP Reports80 citations Open access
Semantic Scholar
ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death.
S. Lhoták, S. Sood, Elise Brimble, Rachel E. Carlisle +5 more
2012AJP - Renal Physiology68 citations
Semantic Scholar
Salicylate improves macrophage cholesterol homeostasis via activation of Ampk
M. Fullerton, R. Ford, Chelsea P. McGregor, Nicholas D. Leblond +8 more
2015Journal of Lipid Research66 citations Open access
Semantic Scholar
Electrical stimulation of the vagus nerve modulates the histamine content of mast cells in the rat jejunal mucosa
T. Gottwald, B. Hewlett, S. Lhoták, R. Stead
1995NeuroReport63 citations
Semantic Scholar
Evidence that Colitis Is Initiated by Environmental Stress and Sustained by Fecal Factors in the Cotton-Top Tamarin (Saguinus oedipus)
J. Wood, O. C. Peck, K. S. Tefend, M. Stonerook +4 more
2000Digestive Diseases and Sciences62 citations
Semantic Scholar
A Mouse Homologue of the Drosophila Tumor Suppressor l(2)tid Gene Defines a Novel Ras GTPase-activating Protein (RasGAP)-binding Protein*
G. Trentin, Xianhua Yin, S. Tahir, S. Lhoták +3 more
2001Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Cystathionine Protects against Endoplasmic Reticulum Stress-induced Lipid Accumulation, Tissue Injury, and Apoptotic Cell Death*
K. Maclean, L. Greiner, Jeffrey T. R. Evans, S. Sood +7 more
2012Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Immunohistochemical detection of N-homocysteinylated proteins in humans and mice.
J. Perła-Kaján, O. Stanger, Michał W. Luczak, A. Ziółkowska +5 more
2008Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie57 citations
Semantic Scholar
Prothrombotic Effects of Hyperhomocysteinemia and Hypercholesterolemia in ApoE-Deficient Mice
Katina M. Wilson, Ryan B. McCaw, Lorie Leo, E. Arning +4 more
2007Arteriosclerosis, Thrombosis and Vascular Biology56 citations Open access
Semantic Scholar
Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice
Elizabeth J. White, Gabriel Gyulay, S. Lhoták, M. Szewczyk +7 more
2018Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions
J. Dickhout, S. Lhoták, Brooke A. Hilditch, Sana Basseri +7 more
2011The FASEB Journal53 citations
Semantic Scholar
Taxol involution of collagen-induced arthritis: ultrastructural correlation with the inhibition of synovitis and neovascularization.
A. Arsenault, S. Lhoták, W. Hunter, M. L. C. Banquerigo +1 more
1998Clinical Immunology and Immunopathology53 citations
Semantic Scholar
Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice
Ji Zhou, G. Werstuck, S. Lhoták, Yuan Y. Shi +7 more
2008The FASEB Journal49 citations Open access
Semantic Scholar
Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions.
E. Crane, Ali A. Al-Hashimi, Jack Chen, E. Lynn +13 more
2018JCI Insight47 citations Open access
Semantic Scholar
Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth
S. Lhoták, Gabriel Gyulay, J. Cutz, Ali A. Al-Hashimi +7 more
2016Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease43 citations Open access
Semantic Scholar
Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism*
P. Lebeau, Ali A. Al-Hashimi, S. Sood, S. Lhoták +8 more
2016Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Loss of TDAG51 Results in Mature-Onset Obesity, Hepatic Steatosis, and Insulin Resistance by Regulating Lipogenesis
Sana Basseri, S. Lhoták, M. Fullerton, R. Palanivel +6 more
2012Diabetes38 citations Open access
Semantic Scholar
Deficiency of TDAG51 Protects Against Atherosclerosis by Modulating Apoptosis, Cholesterol Efflux, and Peroxiredoxin‐1 Expression
Gazi S. Hossain, E. Lynn, K. Maclean, Ji Zhou +14 more
2013Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease35 citations Open access
Semantic Scholar
Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome: a balancing act between plaque stability and rupture.
J. Dickhout, S. Colgan, S. Lhoták, R. Austin
2007Circulation35 citations Open access
Semantic Scholar
Novel function of Oncostatin M as a potent tumour‐promoting agent in lung
S. Lauber, Steven Wong, J. Cutz, Minoru Tanaka +4 more
2015International Journal of Cancer33 citations Open access
Semantic Scholar
Immunolocalization of matrix metalloproteinases and their inhibitors in clinical specimens of bone metastasis from breast carcinoma
S. Lhoták, L. Elavathil, S. Vukmirović-Popović, W. Duivenvoorden +2 more
2004Clinical and Experimental Metastasis30 citations
Semantic Scholar
Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained
P. Lebeau, Khrystyna Platko, Ali A. Al-Hashimi, J. Byun +8 more
2018Journal of Biological Chemistry28 citations Open access
Semantic Scholar
IL‐6 mediates ER expansion during hyperpolarization of alternatively activated macrophages
Ehab A. Ayaub, Karun Tandon, M. Padwal, J. Imani +14 more
2018Immunology and Cell Biology27 citations Open access
Semantic Scholar
Morphological, histomorphometric, and microstructural alterations in human bone metastasis from breast carcinoma.
S. Vukmirović-Popović, N. Colterjohn, S. Lhoták, W. Duivenvoorden +2 more
2002Bone24 citations
Semantic Scholar
4‐Phenylbutyrate protects against atherosclerotic lesion growth by increasing the expression of HSP25 in macrophages and in the circulation of Apoe−/− mice
E. Lynn, S. Lhoták, P. Lebeau, J. Byun +5 more
2019The FASEB Journal21 citations
Semantic Scholar
Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor
Ali A. Al-Hashimi, P. Lebeau, Fadwa Majeed, Enio Polena +16 more
2017Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Immunohistochemical detection of the unfolded protein response in atherosclerotic plaques.
S. Lhoták, Ji Zhou, R. Austin
2011Methods in Enzymology20 citations
Semantic Scholar
Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo
W. Duivenvoorden, L. Beatty, S. Lhoták, B. Hill +6 more
2013British Journal of Cancer18 citations Open access
Semantic Scholar
Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression
N. Kleinmann, W. Duivenvoorden, S. Hopmans, L. Beatty +7 more
2014Clinical and Experimental Metastasis17 citations
Semantic Scholar
Salsalate reduces atherosclerosis through AMPKβ1 in mice
Emily A. Day, R. Ford, Brennan K. Smith, Vanessa P. Houde +9 more
2021Molecular Metabolism16 citations Open access
Semantic Scholar
Taxol (paclitaxel) involution of articular cartilage destruction in collagen induced arthritis: an ultrastructural demonstration of an increased superficial chondroprotective layer.
A. Arsenault, S. Lhoták, W. Hunter, M. Banquerigo +1 more
2000Journal of Rheumatology13 citations
Semantic Scholar
Endothelial injury causes degradation of adjacent basement membranes and promotes their invasion by A549 carcinoma cells.
E. Missirlis, M. Whaley, S. Lhoták, F. Orr
1992Invasion and Metastasis13 citations
Semantic Scholar
TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells
Khrystyna Platko, P. Lebeau, Gabriel Gyulay, S. Lhoták +10 more
2020Arteriosclerosis, Thrombosis and Vascular Biology12 citations Open access
Semantic Scholar
Do gastric mucosal nerves remodel in H. pylori gastritis
R. Stead, B. Hewlett, S. Lhoták, E. Colley +2 more
199410 citations
Semantic Scholar
Effects of subdiaphragmatic vagotomy on mucosal mast cell densities in stomach and jejunum of rats.
T. Gottwald, S. Lhoták, R. Stead
1995Advances in Experimental Medicine and Biology9 citations
Semantic Scholar
Prenatal stress enhances severity of atherosclerosis in the adult apolipoprotein E-deficient mouse offspring via inflammatory pathways.
Huang Ho, S. Lhoták, M. E. Solano, Khalil Karimi +3 more
2013Journal of Developmental Origins of Health and Disease8 citations
Semantic Scholar
Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice
T. Yousof, C. Bouchard, Mihnea Alb, E. Lynn +14 more
2024Journal of Biological Chemistry5 citations Open access
Semantic Scholar
Bone metastasis in human breast and prostate cancer: Involvement of matrix metalloproteinases
W. Duivenvoorden, S. Lhoták, F. Lee, R. Tozer +2 more
20003 citations
Semantic Scholar
Macrophage Differentiation Involves Activation of the Unfolded Protein Response
J. Dickhout, S. Colgan, Brooke A. Hilditch, Sana Basseri +3 more
20082 citations
Semantic Scholar
Restoration of hepatic TDAG51 expression improves insulin signaling and reduces weight gain in mouse models of non‐alcoholic fatty liver disease
Tamana Rubina Yousof, C. Bouchard, Mihnea Alb, E. Lynn +8 more
20181 citations
Semantic Scholar
Targeting Liver ATP-Citrate Lyase with Bempedoic Acid: A Complementary LDL-C Lowering Strategy for Treating Hypercholesterolemia
Stephen L. Pinkosky, R. Newton, Emily A. Day, R. Ford +8 more
2018Atherosclerosis Supplements1 citations
Semantic Scholar

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