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T. Kozai · SciRah

Researcher profile · Semantic Scholar

T. Kozai

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T. Kozai — researcher profile on SciRah

h-index: 22
Works: 48
Citations: 2,311

Most-cited papers

Glial responses to implanted electrodes in the brain
J. Salatino, K. Ludwig, T. Kozai, Erin K. Purcell
2017Nature Biomedical Engineering599 citations Open access
Semantic Scholar
Mechanical failure modes of chronically implanted planar silicon-based neural probes for laminar recording
T. Kozai, Kasey Catt, Xia Li, Zhannetta V. Gugel +3 more
2014Biomaterials219 citations Open access
Semantic Scholar
Chronic tissue response to carboxymethyl cellulose based dissolvable insertion needle for ultra-small neural probes.
T. Kozai, Zhannetta V. Gugel, Xia Li, Peter J. Gilgunn +5 more
2014Biomaterials195 citations
Semantic Scholar
Multi-scale, multi-modal analysis uncovers complex relationship at the brain tissue-implant neural interface: New Emphasis on the Biological Interface
Nicholas J. Michelson, Alberto L. Vazquez, J. Eles, Joseph W. Salatino +4 more
2018Journal of Neural Engineering132 citations Open access
Semantic Scholar
Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease
N. Fitz, K. Nam, Cody M. Wolfe, Florent Letronne +9 more
2021Nature Communications128 citations Open access
Semantic Scholar
Photoelectric artefact from optogenetics and imaging on microelectrodes and bioelectronics: New Challenges and Opportunities
T. Kozai, A. Vazquez
2015Journal of materials chemistry. B121 citations Open access
Semantic Scholar
Revealing Spatial and Temporal Patterns of Cell Death, Glial Proliferation, and Blood-Brain Barrier Dysfunction Around Implanted Intracortical Neural Interfaces
S. Wellman, Le-Hong Li, Yalikun Yaxiaer, Ingrid McNamara +1 more
2019Frontiers in Neuroscience84 citations Open access
Semantic Scholar
Melatonin Improves Quality and Longevity of Chronic Neural Recording
Asiyeh Golabchi, Bing-Chen Wu, Xia Li, D. Carlisle +3 more
2018Biomaterials74 citations Open access
Semantic Scholar
In vivo spatiotemporal dynamics of NG2 glia activity caused by neural electrode implantation
S. Wellman, T. Kozai
2018Biomaterials73 citations Open access
Semantic Scholar
Elastomeric and soft conducting microwires for implantable neural interfaces
C. Kolarcik, S. Luebben, S. Sapp, J. Hanner +7 more
2015Soft Matter72 citations Open access
Semantic Scholar
In vivo spatiotemporal dynamics of astrocyte reactivity following neural electrode implantation
Sajishnu Savya, Fan Li, S. Lam, S. Wellman +4 more
2022bioRxiv52 citations Open access
Semantic Scholar
In vivo microstimulation with cathodic and anodic asymmetric waveforms modulates spatiotemporal calcium dynamics in cortical neuropil and pyramidal neurons of male mice
K. Stieger, J. Eles, K. Ludwig, T. Kozai
2019bioRxiv52 citations Open access
Semantic Scholar
In vivo spatiotemporal patterns of oligodendrocyte and myelin damage at the neural electrode interface.
Keying Chen, S. Wellman, Yalikun Yaxiaer, J. Eles +1 more
2020Biomaterials50 citations Open access
Semantic Scholar
In vivo imaging of calcium and glutamate responses to intracortical microstimulation reveals distinct temporal responses of the neuropil and somatic compartments in layer II/III neurons
J. Eles, T. Kozai
2020Biomaterials46 citations Open access
Semantic Scholar
Cuprizone-induced oligodendrocyte loss and demyelination impairs recording performance of chronically implanted neural interfaces
S. Wellman, Kelly M Guzman, K. Stieger, Lauren E Brink +5 more
2020Biomaterials46 citations Open access
Semantic Scholar
The role of oligodendrocytes and their progenitors on neural interface technology: A novel perspective on tissue regeneration and repair
S. Wellman, F. Cambi, T. Kozai
2018Biomaterials44 citations Open access
Semantic Scholar
Mitochondria modulate programmed neuritic retraction
S. Baranov, O. Baranova, S. Yablonska, Y. Suofu +10 more
2018Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
Optogenetic investigation of the variable neurovascular coupling along the interhemispheric circuits
B. Iordanova, A. Vazquez, T. Kozai, M. Fukuda +1 more
2018Journal of Cerebral Blood Flow and Metabolism38 citations Open access
Semantic Scholar
Dynamic amplitude modulation of microstimulation evokes biomimetic onset and offset transients and reduces depression of evoked calcium responses in sensory cortices
Christopher L. Hughes, T. Kozai
2023Brain Stimulation33 citations Open access
Semantic Scholar
Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation
Fan Li, Jazlyn Gallego, Natasha N Tirko, Jenna Greaser +13 more
2024Nature Communications25 citations Open access
Semantic Scholar
Intracortical Neural Stimulation With Untethered, Ultrasmall Carbon Fiber Electrodes Mediated by the Photoelectric Effect
K. Stocking, A. Vazquez, T. Kozai
2019IEEE Transactions on Biomedical Engineering24 citations
Semantic Scholar
Design Choices for Next-Generation Neurotechnology Can Impact Motion Artifact in Electrophysiological and Fast-Scan Cyclic Voltammetry Measurements
E. Nicolai, Nicholas J. Michelson, Megan L. Settell, S. Hara +6 more
2018Micromachines24 citations Open access
Semantic Scholar
The Argo: A 65,536 channel recording system for high density neural recording in vivo
K. Sahasrabuddhe, A. Khan, Aditya P Singh, Tyler M Stern +28 more
2020bioRxiv21 citations Open access
Semantic Scholar
The History and Horizons of Microscale Neural Interfaces
T. Kozai
2018Micromachines20 citations Open access
Semantic Scholar
Spatiotemporal properties of cortical excitatory and inhibitory neuron activation by sustained and bursting electrical microstimulation
Christopher L. Hughes, K. Stieger, Keying Chen, Alberto L. Vazquez +1 more
2024bioRxiv19 citations
Semantic Scholar
Challenges and Opportunities of Advanced Gliomodulation Technologies for Excitation-Inhibition Balance of Brain Networks
Keying Chen, K. Stieger, T. Kozai
2021Current Opinion in Biotechnology18 citations Open access
Semantic Scholar
Pro-myelinating Clemastine administration improves recording performance of chronically implanted microelectrodes and nearby neuronal health
Keying Chen, F. Cambi, T. Kozai
2023bioRxiv16 citations Open access
Semantic Scholar
Potential of Photoelectric Stimulation with Ultrasmall Carbon Electrode on Neural Tissue: New Directions in Neurostimulation Technology Development
Keying Chen, Bing-Chen Wu, Daniela D. Krahe, Alberto L. Vazquez +5 more
2024Advanced Functional Materials15 citations Open access
Semantic Scholar
Publisher Correction: Glial responses to implanted electrodes in the brain
J. Salatino, K. Ludwig, T. Kozai, Erin K. Purcell
2017Nature Biomedical Engineering14 citations Open access
Semantic Scholar
Cell-specific alterations in autophagy-lysosomal activity near the chronically implanted microelectrodes
Keying Chen, C. G. Padilla, K. Kiselyov, T. Kozai
2023Biomaterials12 citations Open access
Semantic Scholar
Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation
Fan Li, Jazlyn Gallego, Natasha N Tirko, Jenna Greaser +12 more
2023bioRxiv10 citations Open access
Semantic Scholar
Pro-myelinating Clemastine administration improves recording performance of chronically implanted microelectrodes and nearby neuronal health
Keying Chen, F. Cambi, T. Kozai
2023Biomaterials10 citations Open access
Semantic Scholar
Dynamic changes in structure and function of brain mural cells around chronically implanted microelectrodes
S. Wellman, Adam M. Forrest, Madeline M. Douglas, Ashwat Subbaraman +2 more
2024bioRxiv7 citations Open access
Semantic Scholar
Dynamic changes in the structure and function of brain mural cells around chronically implanted microelectrodes.
S. Wellman, Adam M. Forrest, Madeline M. Douglas, Ashwat Subbaraman +2 more
2024Biomaterials6 citations Open access
Semantic Scholar
Potential of Photoelectric Stimulation with Ultrasmall Carbon Electrode on Neural Tissue: New Directions in Neuromodulation Technology Development
Keying Chen, Bing-Chen Wu, Daniela D. Krahe, Alberto L. Vazquez +5 more
2024bioRxiv3 citations Open access
Semantic Scholar
Astrocytes modulate stimulation-induced neural activity during intracortical microstimulation
K. Stieger, Alberto L. Vazquez, T. Kozai
2025Brain Stimulation2 citations Open access
Semantic Scholar
The sixth bioelectronic medicine summit: Neurotechnologies for individuals and communities
Siyar Bahadir, Jacob T. Robinson, L. Morse, Paul B. Yoo +8 more
2026Bioelectronics in Medicine1 citations Open access
Semantic Scholar
Neuronal functional connectivity is impaired in a layer dependent manner near the chronically implanted microelectrodes
Keying Chen, Adam M. Forrest, G. González-Burgos, T. Kozai
2023bioRxiv1 citations Open access
Semantic Scholar
Aberrant accumulation of age- and disease-associated factors following neural probe implantation in a mouse model of Alzheimer’s disease
S. Wellman, Olivia A. Coyne, Madeline M. Douglas, T. Kozai
2023bioRxiv1 citations Open access
Semantic Scholar
Chronic alteration of Ca2+ and hemodynamic signals induced by intracortical microstimulation in the visual cortex of awake mice
Naofumi Suematsu, Alberto L. Vazquez, T. Kozai
2026Biomaterials0 citations Open access
Semantic Scholar
Aging diminishes interlaminar functional connectivity in the mouse cortical V1 and CA1 hippocampal regions
Teresa T. D. Thai, S. Wellman, Naofumi Suematsu, C. G. Padilla +4 more
2025bioRxiv0 citations Open access
Semantic Scholar
Author Correction: Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation
Fan Li, Jazlyn Gallego, Natasha N Tirko, Jenna Greaser +13 more
2024Nature Communications0 citations Open access
Semantic Scholar
Activation and depression of neural and hemodynamic responses induced by the intracortical microstimulation and visual stimulation in the mouse visual cortex
Naofumi Suematsu, Alberto L. Vazquez, T. Kozai
2024bioRxiv0 citations Open access
Semantic Scholar
Understanding spatiotemporal dynamics of intracortical microstimulation using two-photon microscopy in the sensory cortices of mice
T. Kozai
2023Brain Stimulation0 citations Open access
Semantic Scholar
Impairment of autophagy-lysosomal activity near the chronically implanted microelectrodes
Keying Chen, C. G. Padilla, K. Kiselyov, T. Kozai
2023bioRxiv0 citations Open access
Semantic Scholar
What directions of improvements in electrode designs should we expect in the next 5-10 years?
Keying Chen, Stephanie Lam, T. Kozai
2019Bioelectronics in Medicine0 citations Open access
Semantic Scholar
Pipette-integrated microelectrodes
T. Kozai, Erin K. Purcell
2019Nature Biomedical Engineering0 citations Open access
Semantic Scholar
Paleoenviromental reconstruction of Cretaceous lacustrine succession in Xinjiang-Uygur Autonomous Region
K. Arai, T. Ohta, H. Hirano, Syun Harigaya +3 more
20140 citations
Semantic Scholar

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