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M. Lackmann · SciRah

Researcher profile · Semantic Scholar

M. Lackmann

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M. Lackmann — researcher profile on SciRah

h-index: 38
Works: 87
Citations: 5,518

Most-cited papers

Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
J. Himanen, M. Chumley, M. Lackmann, Chen Li +8 more
2004Nature Neuroscience490 citations
Semantic Scholar
Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
P. W. Janes, N. Saha, W. Barton, M. V. Kolev +6 more
2005Cell487 citations Open access
Semantic Scholar
Crystal structure of an Eph receptor–ephrin complex
J. Himanen, K. Rajashankar, M. Lackmann, C. Cowan +2 more
2001Nature355 citations
Semantic Scholar
Therapeutic targeting of EPH receptors and their ligands
A. Boyd, P. Bartlett, M. Lackmann
2013Nature reviews. Drug discovery335 citations
Semantic Scholar
Architecture of Eph receptor clusters
J. Himanen, L. Yermekbayeva, P. W. Janes, J. Walker +7 more
2010Proceedings of the National Academy of Sciences of the United States of America275 citations Open access
Semantic Scholar
Eph/Ephrin signaling in injury and inflammation.
M. Coulthard, M. Morgan, T. Woodruff, T. Arumugam +4 more
2012American Journal of Pathology224 citations Open access
Semantic Scholar
EphA3 maintains tumorigenicity and is a therapeutic target in glioblastoma multiforme.
B. Day, B. Stringer, F. Al-Ejeh, Michael J. Ting +20 more
2013Cancer Cell217 citations Open access
Semantic Scholar
Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling.
I. Lawrenson, Sabine H. Wimmer-Kleikamp, P. Lock, S. Schoenwaelder +4 more
2002Journal of Cell Science180 citations
Semantic Scholar
The structure of Bcl‐w reveals a role for the C‐terminal residues in modulating biological activity
M. G. Hinds, M. Lackmann, Gretchen L. Skea, Penny J. Harrison +2 more
2003EMBO Journal167 citations Open access
Semantic Scholar
Eph, a Protein Family Coming of Age: More Confusion, Insight, or Complexity?
M. Lackmann, A. Boyd
2008Science Signaling161 citations
Semantic Scholar
Recruitment of Eph receptors into signaling clusters does not require ephrin contact
Sabine H. Wimmer-Kleikamp, P. W. Janes, A. Squire, P. Bastiaens +1 more
2004Journal of Cell Biology150 citations Open access
Semantic Scholar
S100 protein CP‐10 stimulates myeloid cell chemotaxis without activation
C. Cornish, Jannine M. Devery, P. Poronnik, M. Lackmann +2 more
1996Journal of Cellular Physiology126 citations
Semantic Scholar
Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity
Julie C. Wilson-Annan, L. O'Reilly, S. Crawford, G. Hausmann +9 more
2003Journal of Cell Biology122 citations Open access
Semantic Scholar
Distinct Subdomains of the EphA3 Receptor Mediate Ligand Binding and Receptor Dimerization*
M. Lackmann, A. C. Oates, M. Dottori, Fiona M. Smith +4 more
1998Journal of Biological Chemistry116 citations Open access
Semantic Scholar
Purification and structural analysis of a murine chemotactic cytokine (CP-10) with sequence homology to S100 proteins.
M. Lackmann, C. Cornish, R. Simpson, R. Moritz +1 more
1992Journal of Biological Chemistry114 citations Open access
Semantic Scholar
Concepts and consequences of Eph receptor clustering.
P. W. Janes, E. Nievergall, M. Lackmann
2012Seminars in Cell and Developmental Biology110 citations
Semantic Scholar
Dissecting the EphA3/Ephrin-A5 Interactions Using a Novel Functional Mutagenesis Screen*
Fiona M. Smith, Christopher J. Vearing, M. Lackmann, H. Treutlein +5 more
2004Journal of Biological Chemistry106 citations Open access
Semantic Scholar
Eph-dependent cell-cell adhesion and segregation in development and cancer
E. Nievergall, M. Lackmann, P. W. Janes
2011Cellular and Molecular Life Sciences105 citations Open access
Semantic Scholar
Eph receptor function is modulated by heterooligomerization of A and B type Eph receptors
P. W. Janes, Bettina Griesshaber, Lakmali Atapattu, E. Nievergall +9 more
2011Journal of Cell Biology99 citations Open access
Semantic Scholar
Structural Determinants of the Interaction between the erbB2 Receptor and the Src Homology 2 Domain of Grb7*
P. W. Janes, M. Lackmann, W. Church, G. Sanderson +2 more
1997Journal of Biological Chemistry92 citations Open access
Semantic Scholar
Cytoplasmic Relaxation of Active Eph Controls Ephrin Shedding by ADAM10
P. W. Janes, Sabine H. Wimmer-Kleikamp, A. Frangakis, Kane Treble +7 more
2009PLoS Biology91 citations Open access
Semantic Scholar
Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironment.
Mary E. Vail, C. Murone, April Tan, L. Hii +13 more
2014Cancer Research83 citations Open access
Semantic Scholar
Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: potential as EphA3-specific tumor-targeting reagents.
Christopher J. Vearing, F. Lee, Sabine H. Wimmer-Kleikamp, V. Spirkoska +7 more
2005Cancer Research81 citations Open access
Semantic Scholar
Ligand for EPH-related Kinase (LERK) 7 Is the Preferred High Affinity Ligand for the HEK Receptor*
M. Lackmann, R. J. Mann, Lucy Kravets, Fiona M. Smith +7 more
1997Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Reproductive Biology and Endocrinology Expression of Nodal Signalling Components in Cycling Human Endometrium and in Endometrial Cancer
I. Papageorgiou, Peter K. Nicholls, Fang Wang, M. Lackmann +13 more
76 citations
Semantic Scholar
Signals from Eph and Ephrin Proteins: A Developmental Tool Kit
A. Boyd, M. Lackmann
2001Science's STKE75 citations
Semantic Scholar
An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth
Lakmali Atapattu, N. Saha, Chanly Chheang, M. Eissman +17 more
2016Journal of Experimental Medicine73 citations Open access
Semantic Scholar
Eph‐modulated Cell Morphology, Adhesion and Motility in Carcinogenesis
Sabine H. Wimmer-Kleikamp, M. Lackmann
2005IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology72 citations Open access
Semantic Scholar
PTP1B regulates Eph receptor function and trafficking
E. Nievergall, P. W. Janes, Carolin Stegmayer, Mary E. Vail +5 more
2010Journal of Cell Biology69 citations Open access
Semantic Scholar
The role of the Eph-ephrin signalling system in the regulation of developmental patterning.
M. Coulthard, S. Duffy, Michelle Down, Betty Evans +8 more
2002International Journal of Developmental Biology69 citations Open access
Semantic Scholar
Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: prevalence of latent STAT1 in high-molecular weight complexes.
M. Lackmann, A. Harpur, A. C. Oates, R. J. Mann +6 more
1998Growth Factors61 citations Open access
Semantic Scholar
Elevated protein tyrosine phosphatase activity provokes Eph/ephrin-facilitated adhesion of pre-B leukemia cells.
Sabine H. Wimmer-Kleikamp, E. Nievergall, Kristina Gegenbauer, S. Adikari +5 more
2008Blood60 citations
Semantic Scholar
The role of proteases in regulating Eph/ephrin signaling
Lakmali Atapattu, M. Lackmann, P. W. Janes
2014Cell Adhesion & Migration55 citations Open access
Semantic Scholar
“Eph receptor signalling; dimerisation just isn't enough”
Christopher J. Vearing, M. Lackmann
2005Growth Factors54 citations
Semantic Scholar
Eph/ephrin signalling and function in oncogenesis: lessons from embryonic development.
P. W. Janes, S. Adikari, M. Lackmann
2008Current Cancer Drug Targets46 citations
Semantic Scholar
Recombinant and Cellular Expression of the Murine Chemotactic Protein, CP-10
Suri E. Iismaa, Sheng-Ping Hu, M. Kocher, M. Lackmann +3 more
1994DNA and Cell Biology45 citations
Semantic Scholar
Antibodies binding the ADAM10 substrate recognition domain inhibit Eph function
Lakmali Atapattu, N. Saha, C. Llerena, Mary E. Vail +4 more
2012Journal of Cell Science43 citations Open access
Semantic Scholar
Improved Symmetric-SIFT for Multi-modal Image Registration
Md. Tanvir Hossain, Guohua Lv, S. Teng, Guo-Jun Lu +1 more
20112011 International Conference on Digital Image Computing: Techniques and Applications43 citations
Semantic Scholar
Three Distinct Molecular Surfaces in Ephrin-A5 Are Essential for a Functional Interaction with EphA3*[boxs]
B. Day, Catherine To, J. Himanen, Fiona M. Smith +3 more
2005Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Hypoxia-Controlled EphA3 Marks a Human Endometrium-Derived Multipotent Mesenchymal Stromal Cell that Supports Vascular Growth
Catherine To, R. Farnsworth, Mary E. Vail, Chanly Chheang +7 more
2014PLoS ONE28 citations Open access
Semantic Scholar
Poliovirus-associated protein kinase: destabilization of the virus capsid and stimulation of the phosphorylation reaction by Zn2+
M. Ratka, M. Lackmann, C. Ueckermann, U. Karlins +1 more
1989Journal of Virology24 citations Open access
Semantic Scholar
Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA
Míriam Javier-Torrent, S. Marco, Daniel Rocandio, Maria Pons-Vizcarra +4 more
2019eLife18 citations Open access
Semantic Scholar
Crystal structure of the human ephrin‐A5 ectodomain
D. Nikolov, Chen Li, M. Lackmann, P. Jeffrey +1 more
2007Protein Science18 citations Open access
Semantic Scholar
The 3T3-L1 Fibroblast to Adipocyte Conversion is Accompanied by Increased Expression of Angiopoietin-1, A Ligand for Tie2
S. Stacker, A. Runting, C. Caesar, A. Vitali +4 more
2000Growth Factors18 citations
Semantic Scholar
EphA3 targeting reduces in vitro adhesion and invasion and in vivo growth and angiogenesis of multiple myeloma cells
F. La Rocca, I. Airoldi, E. Di Carlo, Pina Marotta +15 more
2017Cellular Oncology17 citations Open access
Semantic Scholar
Deconstructing the interaction of glu-plasminogen with its receptor α-enolase
N. Andronicos, M. Baker, M. Lackmann, M. Ranson
200015 citations
Semantic Scholar
Targeting of EPH receptor tyrosine kinases for anticancer therapy.
E. Nievergall, T. Saunders, M. Lackmann
2012Critical reviews in oncogenesis12 citations
Semantic Scholar
PTP-PEST controls EphA3 activation and ephrin-induced cytoskeletal remodelling
Mariam Mansour, E. Nievergall, Kristina Gegenbauer, C. Llerena +5 more
2016Journal of Cell Science11 citations Open access
Semantic Scholar
An Enhancement to SIFT-Based Techniques for Image Registration
Md. Tanvir Hossain, S. Teng, Guo-Jun Lu, M. Lackmann
20102010 International Conference on Digital Image Computing: Techniques and Applications11 citations
Semantic Scholar
Familial hypoparathyroidism due to an abnormal parathyroid hormone molecule.
A. McElduff, Margaret R. Wilkinson, M. Lackmann, S. Grant +4 more
1989Australian and New Zealand Journal of Medicine10 citations
Semantic Scholar

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E. Nievergall×8
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