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S. Fleming · SciRah

Researcher profile · Semantic Scholar

S. Fleming

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S. Fleming — researcher profile on SciRah

h-index: 44
Works: 154
Citations: 10K

Most-cited papers

The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia
J. Srigley, B. Delahunt, J. Eble, L. Egevad +131 more
2013American Journal of Surgical Pathology1,016 citations Open access
Semantic Scholar
Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice.
H. Masuzaki, Hiroshi Yamamoto, C. Kenyon, J. Elmquist +8 more
2003Journal of Clinical Investigation463 citations Open access
Semantic Scholar
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
Xu Huang, S. Wullschleger, N. Shpiro, Victoria A. McGuire +5 more
2008Biochemical Journal416 citations Open access
Semantic Scholar
Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene
C. Boulter, S. Mulroy, S. Webb, S. Fleming +2 more
2001Proceedings of the National Academy of Sciences of the United States of America327 citations Open access
Semantic Scholar
Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.
Y. Kotelevtsev, Roger W. Brown, S. Fleming, C. Kenyon +3 more
1999Journal of Clinical Investigation306 citations Open access
Semantic Scholar
Succinate Dehydrogenase (SDH)-deficient Renal Carcinoma: A Morphologically Distinct Entity
A. Gill, O. Hes, T. Papathomas, M. Šedivcová +34 more
2014American Journal of Surgical Pathology292 citations Open access
Semantic Scholar
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis
S. Cardaci, Liang Zheng, G. Mackay, N. V. D. van den Broek +13 more
2015Nature Cell Biology272 citations Open access
Semantic Scholar
Role of the WNK-activated SPAK kinase in regulating blood pressure
Fatema H. Rafiqi, Annie Mercier Zuber, M. Glover, C. Richardson +5 more
2010EMBO Molecular Medicine267 citations Open access
Semantic Scholar
The RNA helicase p68 is a novel Androgen Receptor Co-Activator involved in splicing and is over-expressed in Prostate Cancer
E. Clark, A. Coulson, Caroline Dalgliesh, P. Rajan +8 more
2008Cancer Research199 citations Open access
Semantic Scholar
Renal Tumors Associated With Germline SDHB Mutation Show Distinctive Morphology
A. Gill, N. Pachter, A. Chou, B. Young +8 more
2011American Journal of Surgical Pathology181 citations
Semantic Scholar
Histological evaluation of AMPK signalling in primary breast cancer
Sirwan Hadad, L. Baker, P. Quinlan, K. Robertson +8 more
2009BMC Cancer180 citations Open access
Semantic Scholar
Controlled Hypertension, a Transgenic Toggle Switch Reveals Differential Mechanisms Underlying Vascular Disease*
Surasak Kantachuvesiri, S. Fleming, J. Peters, Barbara S. Peters +5 more
2001Journal of Biological Chemistry171 citations Open access
Semantic Scholar
Targeting AMPK: a new therapeutic opportunity in breast cancer.
Sirwan Hadad, S. Fleming, A. Thompson
2008Critical reviews in oncology/hematology165 citations
Semantic Scholar
Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice.
J. Bayascas, N. Leslie, R. Parsons, S. Fleming +1 more
2005Current Biology150 citations Open access
Semantic Scholar
A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome.
C. Patek, M. Little, S. Fleming, C. Miles +10 more
1999Proceedings of the National Academy of Sciences of the United States of America123 citations Open access
Semantic Scholar
Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution
M. Kováč, C. Navas, S. Horswell, M. Salm +41 more
2015Nature Communications111 citations Open access
Semantic Scholar
Risk of AKI with gentamicin as surgical prophylaxis.
S. Bell, P. Davey, D. Nathwani, C. Marwick +6 more
2014Journal of the American Society of Nephrology106 citations Open access
Semantic Scholar
Diagnostic criteria for oncocytic renal neoplasms: a survey of urologic pathologists.
S. Williamson, R. Gadde, K. Trpkov, M. Hirsch +16 more
2017Human Pathology99 citations Open access
Semantic Scholar
Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene
E. Heath, Dalal Tahri, E. Andermarcher, P. Schofield +2 more
2008BMC Developmental Biology94 citations Open access
Semantic Scholar
Initial characterization of a rat model of diabetic nephropathy.
Marcelo Araujo da Nóbrega, S. Fleming, R. Roman, M. Shiozawa +3 more
2004Diabetes84 citations
Semantic Scholar
Asparagine endopeptidase is required for normal kidney physiology and homeostasis
G. Miller, Stephen P. Matthews, T. Reinheckel, S. Fleming +1 more
2011The FASEB Journal80 citations
Semantic Scholar
Murine Denys-Drash syndrome: evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis.
C. Patek, S. Fleming, C. Miles, Christopher O. C. Bellamy +5 more
2003Human Molecular Genetics76 citations Open access
Semantic Scholar
Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor
Inma M. Berenjeno, J. Guillermet-Guibert, Wayne Pearce, A. Gray +2 more
2011Biochemical Journal73 citations Open access
Semantic Scholar
Kidney biopsy findings in primary Sjögren syndrome.
D. Kidder, E. Rutherford, D. Kipgen, S. Fleming +2 more
2015Nephrology, Dialysis and Transplantation68 citations
Semantic Scholar
Renal carcinoma with giant mitochondria associated with germ‐line mutation and somatic loss of the succinate dehydrogenase B gene
S. Housley, R. Lindsay, B. Young, M. McConachie +6 more
2010Histopathology68 citations
Semantic Scholar
Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27
H. Montgomery, L. Kiernan, C. Whitworth, S. Fleming +4 more
1998Journal of Hypertension66 citations Open access
Semantic Scholar
Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling
A. Atrih, M. Mudaliar, P. Zakikhani, D. Lamont +5 more
2014British Journal of Cancer65 citations Open access
Semantic Scholar
Centre variation in incidence, indication and diagnosis of adult native renal biopsy in Scotland.
E. McQuarrie, B. Mackinnon, B. Young, L. Yeoman +6 more
2009Nephrology, Dialysis and Transplantation65 citations
Semantic Scholar
Precancerous Lesions in the Kidney
H. Van Poppel, Sten Nilsson, F. Algaba, U. Bergerheim +12 more
2000Scandinavian Journal of Urology and Nephrology, Supplementum57 citations
Semantic Scholar
Retransplantation in Alport post-transplant anti-GBM disease.
Gemma Browne, P. Brown, C. Tomson, S. Fleming +5 more
2004Kidney International56 citations Open access
Semantic Scholar
Acute tubulointerstitial nephritis in Scotland.
A. Valluri, L. Hetherington, E. McQuarrie, S. Fleming +4 more
2015QJM : monthly journal of the Association of Physicians55 citations Open access
Semantic Scholar
The wt1‐heterozygous mouse; a model to study the development of glomerular sclerosis
A. Menke, A. Ijpenberg, S. Fleming, Allyson Ross +6 more
2003Journal of Pathology49 citations
Semantic Scholar
Generation and Characterisation of Keratin 7 (K7) Knockout Mice
A. Sandilands, F. Smith, D. Lunny, L. Campbell +7 more
2013PLoS ONE44 citations Open access
Semantic Scholar
Malignant hypertension – the role of the paracrine renin–angiotensin system
S. Fleming
2000Journal of Pathology40 citations
Semantic Scholar
Granulation Rescue and Developmental Marking of Juxtaglomerular Cells Using “Piggy-BAC” Recombination of the Mouse RenLocus*
Linda J. Mullins, Catherine M. Payne, N. Kotelevtseva, G. Brooker +3 more
2000Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Distal nephron neoplasms.
S. Fleming
2015Seminars in diagnostic pathology30 citations
Semantic Scholar
Periprostatic fat adipokine expression is correlated with prostate cancer aggressiveness in men undergoing radical prostatectomy for clinically localized disease
Naief Dahran, M. Szewczyk-Bieda, S. Vinnicombe, S. Fleming +1 more
2019BJU International26 citations Open access
Semantic Scholar
Challenges in Pathologic Staging of Renal Cell Carcinoma: A Study of Interobserver Variability Among Urologic Pathologists
S. Williamson, P. Rao, O. Hes, J. Epstein +27 more
2018American Journal of Surgical Pathology26 citations Open access
Semantic Scholar
Evidence for aldosterone‐dependent growth of renal cell carcinoma
S. King, S. Bray, S. Galbraith, Lesley J Christie +1 more
2014International journal of experimental pathology (Print)26 citations Open access
Semantic Scholar
Angiotensin-converting Enzyme Is a Modifier of Hypertensive End Organ Damage
Xiao-Ju Liu, Christopher O. C. Bellamy, M. Bailey, Linda J. Mullins +9 more
2009Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Association of the D allele of the angiotensin I converting enzyme polymorphism with malignant vascular injury
N. Mayer, A. Forsyth, Surasak Kantachuvesiri, J. Mullins +1 more
2002Molecular Pathology25 citations Open access
Semantic Scholar
Distinct genetic regulation of progression of diabetes and renal disease in the Goto-Kakizaki rat.
Marcelo Araujo da Nóbrega, L. Solberg Woods, S. Fleming, H. Jacob
2009Physiological Genomics22 citations
Semantic Scholar
Data set for the reporting of carcinoma of renal tubular origin: recommendations from the International Collaboration on Cancer Reporting (ICCR)
B. Delahunt, J. Srigley, Meagan Judge, M. Amin +10 more
2019Histopathology20 citations Open access
Semantic Scholar
How moderate changes in Akt T-loop phosphorylation impact on tumorigenesis and insulin resistance
S. Wullschleger, K. Sakamoto, Lana Johnstone, S. Duce +2 more
2010Disease Models & Mechanisms20 citations Open access
Semantic Scholar
Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer
Scott G. Palmer, K. Litvinova, A. Dunaev, S. Fleming +2 more
2016Biomedical Optics Express19 citations Open access
Semantic Scholar
The role of the renin-angiotensin system in malignant vascular injury affecting the systemic and cerebral circulations.
T. Collidge, G. Lammie, S. Fleming, J. J. Mullins
2004Progress in Biophysics and Molecular Biology19 citations Open access
Semantic Scholar
Increased ALK1 copy number and renal cell carcinoma—a case report
C. Ryan, N. Mayer, J. Cunningham, G. Hislop +2 more
2014Virchows Archiv17 citations
Semantic Scholar
Hypertension in mice caused by inactivation of 11 beta-hydroxysteroid dehydrogenase type 2
Y. Kotelevtsev, Roger W. Brown, S. Fleming, C. R. Edwards +2 more
199817 citations
Semantic Scholar
The D153del Mutation in GNB3 Gene Causes Tissue Specific Signalling Patterns and an Abnormal Renal Morphology in Rge Chickens
H. Tummala, S. Fleming, P. Hocking, D. Wehner +5 more
2011PLoS ONE16 citations Open access
Semantic Scholar
Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer
I. El-Mokadem, T. Kidd, N. Pratt, S. Fleming +1 more
2016OncoTarget15 citations Open access
Semantic Scholar

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