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T. Sturgill · SciRah

Researcher profile · Semantic Scholar

T. Sturgill

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T. Sturgill — researcher profile on SciRah

h-index: 56
Works: 111
Citations: 13K

Most-cited papers

Identification of the regulatory phosphorylation sites in pp42/mitogen‐activated protein kinase (MAP kinase).
D. Payne, A. J. Rossomando, P. A. Martino, A. K. Erickson +5 more
1991EMBO Journal978 citations Open access
Semantic Scholar
Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
N. Anderson, J. Maller, N. Tonks, T. Sturgill
1990Nature941 citations
Semantic Scholar
Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate.
Jie Wu, P. Dent, Tomáš Jelínek, A. Wolfman +2 more
1993Science932 citations
Semantic Scholar
Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
T. Sturgill, L. Ray, E. Erikson, James L. Maller
1988Nature912 citations
Semantic Scholar
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro.
P. Dent, W. Haser, T. Haystead, Leigh Ann Vincent +2 more
1992Science609 citations
Semantic Scholar
Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro.
L. Ray, T. Sturgill
1987Proceedings of the National Academy of Sciences of the United States of America479 citations Open access
Semantic Scholar
The Vam6 GEF controls TORC1 by activating the EGO complex.
Matteo Binda, Marie-Pierre Péli-Gulli, Grégory Bonfils, Nicolas Panchaud +4 more
2009Molecules and Cells457 citations Open access
Semantic Scholar
pp90rsk1 Regulates Estrogen Receptor-Mediated Transcription through Phosphorylation of Ser-167
P. Joel, Jeffrey S. Smith, T. Sturgill, T. Fisher +2 more
1998Molecular and Cellular Biology385 citations Open access
Semantic Scholar
Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6.
T. Sturgill, Jie Wu
1991Biochimica et Biophysica Acta377 citations
Semantic Scholar
Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase.
A. J. Rossomando, D. Payne, Michael J. Weber, T. Sturgill
1989Proceedings of the National Academy of Sciences of the United States of America351 citations Open access
Semantic Scholar
Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo.
L. Ray, T. Sturgill
1988Proceedings of the National Academy of Sciences of the United States of America321 citations Open access
Semantic Scholar
Identification of an Extracellular Signal-regulated Kinase (ERK) Docking Site in Ribosomal S6 Kinase, a Sequence Critical for Activation by ERK in Vivo *
J. A. Smith, C. Poteet-Smith, K. Malarkey, T. Sturgill
1999Journal of Biological Chemistry298 citations Open access
Semantic Scholar
MAPKAP Kinase 2 Phosphorylates Tristetraprolin on in Vivo Sites Including Ser178, a Site Required for 14-3-3 Binding*
Carol A Chrestensen, Melanie J. Schroeder, J. Shabanowitz, D. Hunt +3 more
2004Journal of Biological Chemistry290 citations Open access
Semantic Scholar
zeta PKC induces phosphorylation and inactivation of I kappa B‐alpha in vitro.
M. Diaz-Meco, I. Dominguez, L. Sanz, P. Dent +6 more
1994EMBO Journal220 citations Open access
Semantic Scholar
Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases.
P. Dent, T. Jelínek, D. Morrison, Michael J. Weber +1 more
1995Science197 citations
Semantic Scholar
The activating dual phosphorylation of MAPK by MEK is nonprocessive.
W. R. Burack, T. Sturgill
1997Biochemistry194 citations
Semantic Scholar
Characterization of insulin-stimulated microtubule-associated protein kinase. Rapid isolation and stabilization of a novel serine/threonine kinase from 3T3-L1 cells.
L. Ray, T. Sturgill
1988Journal of Biological Chemistry193 citations Open access
Semantic Scholar
Identification by mass spectrometry of threonine 97 in bovine myelin basic protein as a specific phosphorylation site for mitogen-activated protein kinase.
A. K. Erickson, D. Payne, P. A. Martino, A. J. Rossomando +4 more
1990Journal of Biological Chemistry188 citations Open access
Semantic Scholar
Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism
Jie Wu, S. Spiegel, T. Sturgill
1995Journal of Biological Chemistry182 citations Open access
Semantic Scholar
Activation of Raf by ionizing radiation
U. Kasid, S. Suy, P. Dent, S. Ray +2 more
1996Nature171 citations
Semantic Scholar
TOR1 and TOR2 Have Distinct Locations in Live Cells
T. Sturgill, Adiel Cohen, M. Diefenbacher, M. Trautwein +2 more
2008Eukaryotic Cell156 citations Open access
Semantic Scholar
Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation
T. Jelínek, P. Dent, T. Sturgill, Michael J. Weber
1996Molecular and Cellular Biology156 citations Open access
Semantic Scholar
Ordered phosphorylation of p42mapk by MAP kinase kinase
Timothy A. J. Haystead, P. Dent, Jie Wu, Clare M. M. Haystead +1 more
1992FEBS Letters156 citations
Semantic Scholar
Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2
Jie Wu, Jeffrey K. Harrison, P. Dent, K. R. Lynch +2 more
1993Molecular and Cellular Biology147 citations Open access
Semantic Scholar
Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase.
Jie Wu, Jeffrey K. Harrison, Leigh Ann Vincent, Clare M. M. Haystead +5 more
1993Proceedings of the National Academy of Sciences of the United States of America140 citations Open access
Semantic Scholar
Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro
P. Dent, D. Reardon, Deborah K. Morrison, T. Sturgill
1995Molecular and Cellular Biology138 citations Open access
Semantic Scholar
Mammalian Target of Rapamycin Complex 1 (mTORC1) Activity Is Associated with Phosphorylation of Raptor by mTOR*
Lifu Wang, J. Lawrence, T. Sturgill, T. Harris
2009Journal of Biological Chemistry131 citations Open access
Semantic Scholar
Interaction Among Mitochondria, Mitogen‐Activated Protein Kinases, and Nuclear Factor‐κB in Cellular Models of Parkinson's Disease
David S. Cassarino, Erik M. Halvorsen, R. Swerdlow, N. N. Abramova +3 more
2000Journal of Neurochemistry127 citations
Semantic Scholar
Dual phosphorylation and autophosphorylation in mitogen-activated protein (MAP) kinase activation.
Jeng-Horng Her, S. Lakhani, Kai Zu, Jordi Vila +3 more
1993Biochemical Journal125 citations Open access
Semantic Scholar
Divergence in Signal Transduction Pathways of Platelet-derived Growth Factor (PDGF) and Epidermal Growth Factor (EGF) Receptors
C. S. Rani, Fang Wang, E. Fuior, A. Berger +6 more
1997Journal of Biological Chemistry123 citations Open access
Semantic Scholar
Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway
L. Stancato, M. Sakatsume, M. David, P. Dent +10 more
1997Molecular and Cellular Biology114 citations Open access
Semantic Scholar
Muscle proteins related to microtubule associated protein-2 are substrates for an insulin-stimulatable kinase.
T. Sturgill, L. Ray
1986Biochemical and Biophysical Research Communications - BBRC101 citations
Semantic Scholar
Raf-1 is a potential substrate for mitogen-activated protein kinase in vivo.
N. Anderson, Ping Li, L. Marsden, Nidhi Gupta Williams +2 more
1991Biochemical Journal99 citations Open access
Semantic Scholar
Autophosphorylation in vitro of recombinant 42-kilodalton mitogen-activated protein kinase on tyrosine.
Jie Wu, A. J. Rossomando, Jeng-Horng Her, R. D. Del Vecchio +2 more
1991Proceedings of the National Academy of Sciences of the United States of America99 citations Open access
Semantic Scholar
Angiotensinogen gene expression in 3T3-L1 cells.
J. Saye, L. Cassis, T. Sturgill, Kevin R. Lynch +1 more
1989American Journal of Physiology92 citations
Semantic Scholar
Activation in vitro of somatostatin receptor subtypes 2, 3, or 4 stimulates protein tyrosine phosphatase activity in membranes from transfected Ras-transformed NIH 3T3 cells: coexpression with catalytically inactive SHP-2 blocks responsiveness.
D. Reardon, P. Dent, S. L. Wood, Ting Kong +1 more
1997Molecular Endocrinology87 citations Open access
Semantic Scholar
Modulation of c-Myb-induced transcription activation by a phosphorylation site near the negative regulatory domain.
Natasha Aziz, M. R. Miglarese, R. C. Hendrickson, J. Shabanowitz +3 more
1995Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
MNK kinases regulate multiple TLR pathways and innate proinflammatory cytokines in macrophages.
Robert M Rowlett, Carol A Chrestensen, M. Nyce, Mary G Harp +6 more
2008American Journal of Physiology - Gastrointestinal and Liver Physiology80 citations
Semantic Scholar
The phorbol ester-dependent activator of the mitogen-activated protein kinase p42mapk is a kinase with specificity for the threonine and tyrosine regulatory sites.
A. J. Rossomando, Jie Wu, M. Weber, T. Sturgill
1992Proceedings of the National Academy of Sciences of the United States of America80 citations Open access
Semantic Scholar
Identification of Yin-Yang Regulators and a Phosphorylation Consensus for Male Germ Cell-Associated Kinase (MAK)-Related Kinase
Zheng Fu, Katherine A. Larson, R. Chitta, Sirlester A. Parker +8 more
2006Molecular and Cellular Biology78 citations Open access
Semantic Scholar
Defective regulation of mitogen-activated protein kinase activity in a 3T3 cell variant mitogenically nonresponsive to tetradecanoyl phorbol acetate
G. L'allemain, T. Sturgill, Michael J. Weber
1991Molecular and Cellular Biology76 citations Open access
Semantic Scholar
Sequence of pp42/MAP kinase, a serine/threonine kinase regulated by tyrosine phosphorylation
Jeng-Horng Her, Jie Wu, Thomas B. Rall, T. Sturgill +1 more
1991Nucleic Acids Res.73 citations Open access
Semantic Scholar
The MAP kinase ERK5 binds to and phosphorylates p90 RSK.
Aarati Ranganathan, G. Pearson, Carol A Chrestensen, T. Sturgill +1 more
2006Archives of Biochemistry and Biophysics71 citations
Semantic Scholar
ERK2- and p90Rsk2-dependent Pathways Regulate the CCAAT/Enhancer-binding Protein-β Interaction with Serum Response Factor*
M. Hanlon, T. Sturgill, L. Sealy
2001Journal of Biological Chemistry70 citations Open access
Semantic Scholar
Biochemical characterization of a family of serine/threonine protein kinases regulated by tyrosine and serine/threonine phosphorylations.
A. J. Rossomando, J. Sanghera, L. Marsden, Michael J. Weber +2 more
1991Journal of Biological Chemistry70 citations Open access
Semantic Scholar
Glucose Regulates Interleukin-8 Production in Aortic Endothelial Cells through Activation of the p38 Mitogen-activated Protein Kinase Pathway in Diabetes*
Suseela Srinivasan, David T. Bolick, Melissa E. Hatley, R. Natarajan +5 more
2004Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Activation of a Nuclear Cdc2-Related Kinase within a Mitogen-Activated Protein Kinase-Like TDY Motif by Autophosphorylation and Cyclin-Dependent Protein Kinase-Activating Kinase
Zheng Fu, Melanie J. Schroeder, J. Shabanowitz, P. Kaldis +4 more
2005Molecular and Cellular Biology65 citations Open access
Semantic Scholar
Generation of constitutively active p90 ribosomal S6 kinase in vivo. Implications for the mitogen-activated protein kinase-activated protein kinase family.
C. Poteet-Smith, J. A. Smith, D. Lannigan, Tiffany A. Freed +1 more
1999Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Activation of mitogen-activated protein kinase in BC3H1 myocytes by fluoroaluminate.
N. Anderson, E. Kilgour, T. Sturgill
1991Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Functional Mapping of the N-terminal Regulatory Domain in the Human Raf-1 Protein Kinase (*)
Yu-Hua Chow, K. Pumiglia, To-Ni H. Jun, P. Dent +2 more
1995Journal of Biological Chemistry62 citations Open access
Semantic Scholar

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Michael J. Weber×8
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Jie Wu×7
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P. Dent×7
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A. J. Rossomando×6
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