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Fei-Jie Zhang · SciRah

Researcher profile · Semantic Scholar

Fei-Jie Zhang

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Fei-Jie Zhang — researcher profile on SciRah

h-index: 26
Works: 42
Citations: 3,212

Most-cited papers

The biological basis for microRNA target restriction to the 3' untranslated region in mammalian mRNAs
Shuo Gu, Lan Jin, Fei-Jie Zhang, P. Sarnow +1 more
2009Nature Structural &Molecular Biology492 citations Open access
Semantic Scholar
A tRNA-derived small RNA regulates ribosome biogenesis
H. Kim, Gabriele Fuchs, Sheng-Chun Wang, Wei Wei +12 more
2017Nature395 citations Open access
Semantic Scholar
The loop position of shRNAs and pre-miRNAs is critical for the accuracy of Dicer processing in vivo
Shuo Gu, Lan Jin, Yue Zhang, Yong Huang +3 more
2012Cell295 citations Open access
Semantic Scholar
A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo
Jun Chu, Younghee Oh, A. Sens, N. Ataie +17 more
2016Nature Biotechnology256 citations Open access
Semantic Scholar
Promoterless gene targeting without nucleases ameliorates haemophilia B in mice
A. Barzel, N. Paulk, Ying Shi, Yong Huang +7 more
2014Nature250 citations Open access
Semantic Scholar
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
Yi-Chi Su, Joel R. Walker, Yunhee Park, Thomas P Smith +15 more
2020Nature Methods166 citations Open access
Semantic Scholar
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
N. Paulk, K. Pekrun, Erhua Zhu, Sean Nygaard +17 more
2018Molecular Therapy157 citations Open access
Semantic Scholar
Diesel Exhaust Particle-Exposed Human Bronchial Epithelial Cells Induce Dendritic Cell Maturation and Polarization via Thymic Stromal Lymphopoietin
B. Bleck, Doris B. Tse, Maria A. Curotto de Lafaille, Fei-Jie Zhang +1 more
2008Journal of Clinical Immunology140 citations Open access
Semantic Scholar
Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes
Shuo Gu, Lan Jin, Fei-Jie Zhang, Yong Huang +3 more
2011Proceedings of the National Academy of Sciences of the United States of America90 citations Open access
Semantic Scholar
Using a barcoded AAV capsid library to select for novel clinically relevant gene therapy vectors
K. Pekrun, G. de Alencastro, Qing-Jun Luo, Jun Liu +10 more
2019bioRxiv85 citations Open access
Semantic Scholar
Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain
Shuo Gu, Lan Jin, Yong Huang, Fei-Jie Zhang +1 more
2012Current Biology81 citations Open access
Semantic Scholar
Mechanical ventilation with 40% oxygen reduces pulmonary expression of genes that regulate lung development and impairs alveolar septation in newborn mice.
R. Bland, Lucia M. Mokres, Robert D. Ertsey, B. Jacobson +6 more
2007American Journal of Physiology - Lung cellular and Molecular Physiology78 citations
Semantic Scholar
Keratinocyte growth factor and the transcription factors C/EBP alpha, C/EBP delta, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells.
R. Mason, T. Pan, K. Edeen, L. D. Nielsen +4 more
2003Journal of Clinical Investigation73 citations Open access
Semantic Scholar
miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
P. Valdmanis, H. Kim, K. Chu, Fei-Jie Zhang +4 more
2018Nature Communications65 citations Open access
Semantic Scholar
The extragenic spacer length between the 5' and 3' ends of the transgene expression cassette affects transgene silencing from plasmid-based vectors.
Jiamiao Lu, Fei-Jie Zhang, Siqun Xu, Andrew Z. Fire +1 more
2012Molecular Therapy65 citations Open access
Semantic Scholar
The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner
Adriana Gonzalez-Sandoval, K. Pekrun, Shinnosuke Tsuji, Fei-Jie Zhang +3 more
2023Nature Communications60 citations Open access
Semantic Scholar
Transforming growth factor-beta antagonizes alveolar type II cell proliferation induced by keratinocyte growth factor.
Fei-Jie Zhang, L. D. Nielsen, J. Lucas, R. Mason
2004American Journal of Respiratory Cell and Molecular Biology58 citations
Semantic Scholar
A mini-intronic plasmid (MIP): a novel robust transgene expression vector in vivo and in vitro.
Jiamiao Lu, Fei-Jie Zhang, M. Kay
2013Molecular Therapy56 citations Open access
Semantic Scholar
Lipogenesis in fetal rat lung: importance of C/EBPalpha, SREBP-1c, and stearoyl-CoA desaturase.
Fei-Jie Zhang, T. Pan, L. D. Nielsen, R. Mason
2004American Journal of Respiratory Cell and Molecular Biology49 citations
Semantic Scholar
Ribosomal DNA integrating rAAV-rDNA vectors allow for stable transgene expression.
L. Lisowski, Ashley Lau, Zhongya Wang, Yue Zhang +3 more
2012Molecular Therapy36 citations Open access
Semantic Scholar
Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model
Ren Song, K. Pekrun, Themasap A. Khan, Fei-Jie Zhang +2 more
2022bioRxiv34 citations Open access
Semantic Scholar
Aptamer-programmable adeno-associated viral vectors as a novel platform for cell-specific gene transfer
F. Puzzo, Chuan-Ling Zhang, Bethany Powell-Gray, Fei-Jie Zhang +2 more
2023Molecular Therapy: Nucleic Acids33 citations Open access
Semantic Scholar
Weak base pairing in both seed and 3′ regions reduces RNAi off-targets and enhances si/shRNA designs
Shuo Gu, Yue Zhang, Lan Jin, Yong Huang +4 more
2014Nucleic Acids Research33 citations Open access
Semantic Scholar
Serum levels of surfactant protein D are increased in mice with lung tumors.
Fei-Jie Zhang, W. Pao, Sarah M. Umphress, S. Jakowlew +9 more
2003Chest32 citations
Semantic Scholar
A 5′ Noncoding Exon Containing Engineered Intron Enhances Transgene Expression from Recombinant AAV Vectors in vivo
Jiamiao Lu, James A. Williams, J. Luke, Fei-Jie Zhang +2 more
2017Human Gene Therapy27 citations Open access
Semantic Scholar
RNAi induced hepatotoxicity results from loss of the first synthesized isoform of miR-122 in mice
P. Valdmanis, Shuo Gu, K. Chu, Lan Jin +8 more
2016Nature Medicine26 citations Open access
Semantic Scholar
Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice
Shinnosuke Tsuji, C. Stephens, G. Bortolussi, Fei-Jie Zhang +6 more
2022Nature Biotechnology19 citations Open access
Semantic Scholar
Expression of CINC-2β Is Related to the State of Differentiation of Alveolar Epithelial Cells
K. Nishina, Fei-Jie Zhang, L. D. Nielsen, K. Edeen +2 more
200512 citations Open access
Semantic Scholar
Sequence-Modified Antibiotic Resistance Genes Provide Sustained Plasmid-Mediated Transgene Expression in Mammals.
Jiamiao Lu, Fei-Jie Zhang, A. Fire, M. Kay
2016Molecular Therapy11 citations Open access
Semantic Scholar
Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.
G. de Alencastro, F. Puzzo, M. Pavel-Dinu, Fei-Jie Zhang +11 more
2020Molecular Therapy10 citations Open access
Semantic Scholar
Hybrid Palladium-Catalyzed Intramolecular Carboamination of Conjugated Dienes: Synthesis of Functionalized Pyrrolidines via Selective Trifluoromethylarene Defluorination.
Fei-Jie Zhang, Guo-Cong Zhang, Qi-Xin Zhou, Tian-Cen Bian +2 more
2024Journal of Organic Chemistry9 citations
Semantic Scholar
Correlation of antigen expression with epigenetic modifications after rAAV delivery of a hyperactive human Factor IX variant in mice and rhesus macaques.
K. Pekrun, C. Stephens, Adriana Gonzalez-Sandoval, A. Goswami +4 more
2024Molecular Therapy8 citations Open access
Semantic Scholar
Expression of CINC-2beta is related to the state of differentiation of alveolar epithelial cells.
K. Nishina, Fei-Jie Zhang, L. D. Nielsen, K. Edeen +2 more
2005American Journal of Respiratory Cell and Molecular Biology6 citations
Semantic Scholar
Stereo-random oligonucleotides enable efficient recruitment of ADAR in vitro and in vivo
Laura S Pfeiffer, Tobias Merkle, Paul Vogel, Inga Jarmoskaite +14 more
2025Nature Communications4 citations Open access
Semantic Scholar
AAV-mediated genome editing is influenced by the formation of R-loops
Francesco Puzzo, Madzia P. Crossley, A. Goswami, Fei-Jie Zhang +4 more
2024bioRxiv4 citations Open access
Semantic Scholar
Potential effects of endogenous RNA/DNA hybrids on CRISPR-Cas9-mediated homology-directed repair
Francesco Puzzo, Batuhan Bayram, C. Macaubas, Angela Lin +4 more
2026Molecular Therapy: Nucleic Acids0 citations Open access
Semantic Scholar
lnc122 RNA prevents liver tumorigenesis in MYC-driven liver cancer
Hagoon Jang, Fei-Jie Zhang, B. K. Suh, Anh Le +3 more
2026JHEP Reports0 citations Open access
Semantic Scholar
Species-specific AAVR dominates species-tropism of adeno-associated virus (AAV) vectors
M. Kay, Yuqian Jiang, Yiming Liu, Yu-Qing Jing +2 more
2025Research Square0 citations
Semantic Scholar
Capsid-mediated chromatin state of the AAV vector genome controls host species range
Adriana Gonzalez-Sandoval, Shinnosuke Tsuji, Fei-Jie Zhang, King L. Hung +3 more
2022bioRxiv0 citations Open access
Semantic Scholar
Abstract LB-390: A transfer RNA derived small RNA affects translation in rapidly dividing cells and a target for hepatocellular carcinoma
H. Kim, Gabriele Fuchs, Sheng-Chun Wang, Wei Wei +12 more
2018Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
737. RNAi Induced Hepatotoxicity Results from a Functional Depletion of the First Synthesized Isoform of miR-122
P. Valdmanis, Shuo Gu, K. Chu, Lan Jin +8 more
20160 citations Open access
Semantic Scholar
Serum levels of surfactant protein D are increased in mice with lung tumors.
Fei-Jie Zhang, W. Pao, S. Umphress, S. Jakowlew +9 more
2003Cancer Research0 citations
Semantic Scholar

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K. Pekrun×9
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Shuo Gu×7
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Lan Jin — researcher profile on SciRah

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Yong Huang — researcher profile on SciRah

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Jian-Peng Xu×5

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