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Mi Chen · SciRah

Researcher profile · Semantic Scholar

Mi Chen

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Mi Chen — researcher profile on SciRah

h-index: 9
Works: 25
Citations: 347

Most-cited papers

Discovery of sodium R-(+)-4-{2-[5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (elagolix), a potent and orally available nonpeptide antagonist of the human gonadotropin-releasing hormone receptor.
Chen Chen, Dongpei Wu, Zhiqian Guo, Q. Xie +15 more
2008Journal of Medicinal Chemistry114 citations Open access
Semantic Scholar
A convenient solution and solid-phase synthesis of Δ5-2-oxopiperazines via N-acyliminium ions cyclization
Jie Cheng, Mi Chen, T. Arrhenius, A. Nadzan
200260 citations
Semantic Scholar
Discovery and structure-activity relationship of coumarin derivatives as TNF-alpha inhibitors.
Jie Cheng, Mi Chen, David Wallace, Sovouthy Tith +8 more
2004Bioorganic & Medicinal Chemistry Letters47 citations
Semantic Scholar
Discovery of Paltusotine (CRN00808), a Potent, Selective, and Orally Bioavailable Non-peptide SST2 Agonist
Jian Zhao, Shi-Miao Wang, S. Markison, S. H. Kim +10 more
2022ACS Medicinal Chemistry Letters32 citations Open access
Semantic Scholar
Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties.
C. Regan, Zhiqian Guo, Yongsheng Chen, Charles Q. Huang +13 more
2008Bioorganic & Medicinal Chemistry Letters19 citations Open access
Semantic Scholar
Heteroaryl substituted bis-trifluoromethyl carbinols as malonyl-CoA decarboxylase inhibitors.
Jie Cheng, Chi-Ching Mak, Yu-Jin Huang, Richard J. Penuliar +12 more
2006Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Design and synthesis of heterocyclic malonyl-CoA decarboxylase inhibitors.
Jie Cheng, Mi Chen, Bin Liu, Zheng Hou +2 more
2006Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties.
V. Santora, Theresa A. Almos, Richard A. Barido, Jillian Basinger +37 more
2018Journal of Medicinal Chemistry14 citations Open access
Semantic Scholar
Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists.
Mi Chen, Zhiqian Guo, M. Lanier, Li-Ren Zhao +12 more
2007Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Rapid identification of a novel phosphodiesterase 7B tracer for receptor occupancy studies using LC─MS/MS.
Jie Chen, G. Gu, Mi Chen, Trevor Scott +10 more
2020Neurochemistry International6 citations
Semantic Scholar
Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties.
A. Hudson, V. Santora, R. Petroski, Theresa A. Almos +39 more
2020Bioorganic & Medicinal Chemistry Letters6 citations Open access
Semantic Scholar
A traceless solid-phase synthesis of 2-imidazolones
Jie Cheng, Christopher Kaiho, Mi Chen, T. Arrhenius +1 more
20024 citations
Semantic Scholar
A novel nonpeptide drug conjugate (NDC) for the treatment of somatostatin receptor 2-expressing tumors
Jian Zhao, Emmanuel Sturchler, Bing Yang, Mi Chen +14 more
2025Endocrine Abstracts1 citations
Semantic Scholar
Selective Somatostatin 5 (SST5) and Somatostatin 2 (SST2) Nonpeptide Agonists Potently Suppress Glucose- and Tolbutamide-Stimulated Dynamic Insulin Secretion From Isolated Human Islets
Elizabeth Rico, Jian Zhao, Mi Chen, A. Kusnetzow +2 more
2021Journal of the Endocrine Society1 citations Open access
Semantic Scholar
Malonyl coa-decarboxylase inhibitors as metabolic modulators
T. Arrhenius, Mi Chen, Jie Cheng, J. Dyck +7 more
20021 citations
Semantic Scholar
FRI538 Discovery And Characterization Of Orally Bioavailable Nonpeptide Thyroid Stimulating Hormone Receptor (TSHR) Antagonists For The Treatment Of Graves’ Disease
Melissa A. Fowler, Collin Regan, Jian Zhao, Eulalia A Coutinho +11 more
2023Journal of the Endocrine Society0 citations Open access
Semantic Scholar
Composes de cyanoamide utiles en tant qu'inhibiteurs de malonyl-coa decarboxylase
Jie Cheng, Mi Chen, T. Arrhenius, G. Lopaschuk +3 more
20040 citations
Semantic Scholar
Piperidine compounds useful as inhibitors to malonyl coenzyme decarboxylase.
T. Arrhenius, Mi Chen, Jie Cheng, J. Dyck +3 more
20040 citations
Semantic Scholar
Piperidine compounds as malonyl-coa decarboxylase inhibitors
Jie Cheng, Mi Chen, T. Arrhenius, G. Lopaschuk +3 more
20040 citations
Semantic Scholar
Inhibiteurs de malonyl-coa decarboxylase utiles comme modulateurs metaboliques
Thomas S. Arrhenius, Mi Chen, Jie Cheng, Yujin Huang +4 more
20020 citations
Semantic Scholar
Inhibitors useful decarboxylase malonyl CoA as metabolic modulators.
T. Arrhenius, Mi Chen, Jie Cheng, J. Dyck +6 more
20020 citations
Semantic Scholar
Procedes relatifs au traitement de maladies par le biais d'inhibiteurs de malonyl-coa decarboxylase
Thomas S. Arrhenius, Mi Chen, Jie Cheng, Masayuki Haramura +7 more
20020 citations
Semantic Scholar
A Convenient Solution and Solid-Phase Synthesis of Δ5-2-Oxopiperazines via N-Acyliminium Ions Cyclization.
Jie Cheng, Mi Chen, T. Arrhenius, A. Nadzan
20020 citations
Semantic Scholar
DERIVES DE LA COUMARINE UTILISES COMME INHIBITEUR DU TNF$g(a)
Jie Cheng, Thomas S. Arrhenius, D. Wallace, Mi Chen +4 more
20010 citations
Semantic Scholar
Ganodotropin-releasing hormone receptor antagonists and related methods
G. Beaton, Mi Chen, Timothy Coon, Todd J. A. Ewing +9 more
20010 citations
Semantic Scholar

Frequent co-authors

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Jie Cheng×14
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Jie Cheng — researcher profile on SciRah
T. Arrhenius×11
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A. Nadzan×7
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Yun-Fei Zhu×6
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×6

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G. Lopaschuk×6

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R. Struthers×4

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David Wallace×4

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Jian Zhao — researcher profile on SciRah

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Zhiqian Guo — researcher profile on SciRah

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