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D. Weinstock · SciRah

Researcher profile · Semantic Scholar

D. Weinstock

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D. Weinstock — researcher profile on SciRah

h-index: 66
Works: 309
Citations: 17K

Most-cited papers

Next-generation characterization of the Cancer Cell Line Encyclopedia
Mahmoud Ghandi, Franklin W. Huang, Judit Jané-Valbuena, G. Kryukov +64 more
2019Nature2,943 citations Open access
Semantic Scholar
An ‘off-the-shelf’ fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies
M. Cooper, Jaebok Choi, K. Staser, Julie Ritchey +17 more
2018Leukemia354 citations Open access
Semantic Scholar
Activity of the PI3K-δ,γ inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphoma.
S. Horwitz, R. Koch, P. Porcu, Y. Oki +16 more
2018Blood245 citations Open access
Semantic Scholar
AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells
Justin Cidado, S. Boiko, T. Proia, Douglas Ferguson +14 more
2019Clinical Cancer Research219 citations Open access
Semantic Scholar
Reduced mitochondrial apoptotic priming drives resistance to BH3 mimetics in acute myeloid leukemia
S. Bhatt, Marissa S. Pioso, Elyse A. Olesinski, Binyam Yilma +19 more
2020Cancer Cell163 citations Open access
Semantic Scholar
Phase II biomarker-driven study of ruxolitinib demonstrates effectiveness of JAK/STAT targeting in T-cell lymphomas.
A. Moskowitz, P. Ghione, E. Jacobsen, J. Ruan +32 more
2021Blood153 citations Open access
Semantic Scholar
Bruton tyrosine kinase degradation as a therapeutic strategy for cancer.
D. Dobrovolsky, Eric S. Wang, S. Morrow, Catharine S. Leahy +9 more
2019Blood135 citations Open access
Semantic Scholar
DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas
Yonghan He, R. Koch, Vivekananda Budamagunta, Pei-Yi Zhang +12 more
2020Journal of Hematology & Oncology112 citations Open access
Semantic Scholar
RhoA G17V is sufficient to induce autoimmunity and promotes T-cell lymphomagenesis in mice.
S. Ng, L. Brown, K. Stevenson, Tiffany DeSouza +3 more
2018Blood109 citations Open access
Semantic Scholar
Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models
S. Ng, Noriaki Yoshida, A. Christie, Mahmoud Ghandi +43 more
2018Nature Communications100 citations Open access
Semantic Scholar
DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance.
Katsuhiro Togami, Timothy J. Pastika, Jason Stephansky, Mahmoud Ghandi +13 more
2019Journal of Clinical Investigation73 citations Open access
Semantic Scholar
IFITM3 functions as PIP3-scaffold to amplify PI3K signaling in B-cells
Jaewoong Lee, Mark E. Robinson, Ning Ma, Dewan Artadji +25 more
2020Nature72 citations Open access
Semantic Scholar
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma.
D. Bararia, J. Hildebrand, S. Stolz, S. Haebe +34 more
2020Cell Reports70 citations Open access
Semantic Scholar
Chimeric antigen receptor T cells targeting CD79b show efficacy in lymphoma with or without co-targeting CD19
Maria Ormhøj, Irene Scarfò, Maria L. Cabral, Stefanie R. Bailey +17 more
2019Clinical Cancer Research69 citations Open access
Semantic Scholar
Author Correction: IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells
Jaewoong Lee, Mark E. Robinson, Ning Ma, Dewan Artadji +25 more
2021Nature65 citations Open access
Semantic Scholar
Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles.
J. Hellmuth, A. Louissaint, M. Szczepanowski, S. Haebe +16 more
2018Blood65 citations
Semantic Scholar
GENOMIC ANALYSES IDENTIFY RECURRENT ALTERATIONS IN IMMUNE EVASION GENES IN DIFFUSE LARGE B CELL LYMPHOMA, LEG TYPE
X. Zhou, A. Louissaint, Alexander T. Wenzel, Jing-Yi Yang +11 more
2018Journal of Investigative Dermatology65 citations Open access
Semantic Scholar
Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis
Katsuhiro Togami, Sun Sook Chung, V. Madan, Christopher A. G. Booth +26 more
2020bioRxiv64 citations Open access
Semantic Scholar
Targeted Inhibition of CD47-SIRPα Requires Fc-FcγR Interactions to Maximize Activity in T-cell Lymphomas.
Salvia Jain, Alexandria Van Scoyk, E. Morgan, Andrew Matthews +9 more
2019Blood62 citations Open access
Semantic Scholar
Rapid identification of BCR/ABL1-like acute lymphoblastic leukaemia patients using a predictive statistical model based on quantitative real time-polymerase chain reaction: clinical, prognostic and therapeutic implications
S. Chiaretti, M. Messina, S. Grammatico, A. Piciocchi +17 more
2018British Journal of Haematology57 citations Open access
Semantic Scholar
Signaling input from divergent pathways subverts B-cell transformation
Lai N. Chan, Mark A. Murakami, Mark E. Robinson, Rebecca Caeser +25 more
2020Nature56 citations Open access
Semantic Scholar
Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas.
R. Koch, A. Christie, J. Crombie, A. Palmer +12 more
2019Blood51 citations Open access
Semantic Scholar
Genomic landscape of cutaneous follicular lymphomas reveals 2 subgroups with clinically predictive molecular features.
X. Zhou, Jing-Yi Yang, Kimberly G. Ringbloom, M. Martinez-Escala +15 more
2021Blood Advances50 citations Open access
Semantic Scholar
Chemical, Biological, Radiological, Nuclear, and Explosive (CBRNE) Science and the CBRNE Science Medical Operations Science Support Expert (CMOSSE)
C. Coleman, J. Bader, J. Koerner, Chad M. Hrdina +31 more
2019Disaster Medicine and Public Health Preparedness49 citations Open access
Semantic Scholar
Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome–like acute B-cell lymphoblastic leukemia
Qi Zhang, Ce Shi, Li-Na Han, N. Jain +21 more
2018OncoTarget46 citations Open access
Semantic Scholar
Mechanisms of lymphoma clearance induced by high-dose alkylating agents
Chen Lossos, Yunpeng Liu, Kellie E. Kolb, A. Christie +20 more
2019Cancer Discovery44 citations Open access
Semantic Scholar
The Combination of Duvelisib, a PI3K-δ,γ Inhibitor, and Romidepsin Is Highly Active in Relapsed/Refractory Peripheral T-Cell Lymphoma with Low Rates of Transaminitis: Results of Parallel Multicenter, Phase 1 Combination Studies with Expansion Cohorts
S. Horwitz, A. Moskowitz, E. Jacobsen, N. Mehta-Shah +18 more
2018Blood40 citations Open access
Semantic Scholar
Identification of Circulating Serum Multi-MicroRNA Signatures in Human DLBCL Models
A. Beheshti, K. Stevenson, C. Vanderburg, Dashnamoorthy Ravi +6 more
2019Scientific Reports39 citations Open access
Semantic Scholar
A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia
Taku Harada, Y. Heshmati, Jérémie Kalfon, Monika W. Perez +25 more
2021bioRxiv29 citations Open access
Semantic Scholar
Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions.
Noriaki Yoshida, Kay Shigemori, Nicholas Donaldson, Christopher Trevisani +9 more
2019Blood29 citations Open access
Semantic Scholar
Primary Cytotoxic T Cell Lymphomas Harbor Recurrent Targetable Alterations in the JAK-STAT Pathway.
Katie Lee, Mark G Evans, Lei Yang, S. Ng +19 more
2021Blood28 citations Open access
Semantic Scholar
Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair
Jacob V. Layer, Lydie L. Debaize, Alexandria Van Scoyk, N. House +8 more
2020Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma
C. Mastini, M. Campisi, E. Patrucco, Giulia Mura +32 more
2023Science Translational Medicine22 citations
Semantic Scholar
Final Results of a Phase II Biomarker-Driven Study of Ruxolitinib in Relapsed and Refractory T-Cell Lymphoma
A. Moskowitz, P. Ghione, E. Jacobsen, J. Ruan +21 more
2019Blood22 citations Open access
Semantic Scholar
Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia
G. Pouliot, James Degar, L. Hinze, B. Kochupurakkal +17 more
2019PLoS ONE19 citations Open access
Semantic Scholar
Identification and Targeting of the Developmental Blockade in Extranodal Natural Killer/T-cell Lymphoma.
Bethany L. Mundy-Bosse, C. Weigel, Yue-Zhong Wu, Salma B. Abdelbaky +35 more
2022Blood Cancer Discovery18 citations Open access
Semantic Scholar
Low-cost transcriptional diagnostic to accurately categorize lymphomas in low- and middle-income countries.
Fabiola Valvert, Oscar Silva, Elizabeth Solórzano-Ortiz, M. Puligandla +11 more
2021Blood Advances18 citations Open access
Semantic Scholar
A Novel JAK1 Mutant Breast Implant-Associated Anaplastic Large Cell Lymphoma Patient-Derived Xenograft Fostering Pre-Clinical Discoveries
D. Fiore, L. Cappelli, P. Zumbo, J. Phillips +18 more
2020Cancers18 citations Open access
Semantic Scholar
Durable Responses Observed with JAK Inhibition in T-Cell Lymphomas
A. Moskowitz, E. Jacobsen, J. Ruan, J. Schatz +11 more
2018Blood18 citations
Semantic Scholar
LymphoML: An interpretable artificial intelligence-based method identifies morphologic features that correlate with lymphoma subtype
V. Shankar, Xiaoli Yang, V. Krishna, Brent Tan +9 more
2023ML4H@NeurIPS17 citations
Semantic Scholar
ITK Degradation to Block T-cell Receptor Signaling and Overcome Therapeutic Resistance in T-Cell Lymphomas
Bai-Shan Jiang, D. Weinstock, K. Donovan, Hong-Wei Sun +9 more
2023Cell Chemical Biology15 citations Open access
Semantic Scholar
New Scaffolds for Type II JAK2 Inhibitors Overcome the Acquired G993A Resistance Mutation
Matthew L. Arwood, Yao Liu, Shannon K Harkins, D. Weinstock +21 more
2023Cell Chemical Biology15 citations
Semantic Scholar
Targeting Aggressive B-cell Lymphomas through Pharmacological Activation of the Mitochondrial Protease OMA1
A. Schwarzer, Matheus P. Oliveira, M. Kleppa, Scott D. Slattery +15 more
2022bioRxiv13 citations Open access
Semantic Scholar
RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia
David Koschut, Debleena Ray, Zhen-Hua Li, Emanuela Giarin +9 more
2020Oncogene12 citations Open access
Semantic Scholar
Parp3 promotes long-range end joining in murine cells
Jacob V. Layer, J. Cleary, Alexander J. Brown, K. Stevenson +14 more
2018Proceedings of the National Academy of Sciences of the United States of America12 citations Open access
Semantic Scholar
Micro-region transcriptomics of fixed human tissue using Pick-Seq
Z. Maliga, Ajit Johnson Nirmal, N. Ericson, Sarah A. Boswell +11 more
2021bioRxiv11 citations Open access
Semantic Scholar
Challenges and implications of genomics for T-cell lymphomas.
E. Jacobsen, D. Weinstock
2018Hematology. American Society of Hematology. Education Program10 citations Open access
Semantic Scholar
Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia
Barry M. Zee, Kamrine E. Poels, Cong-Hui Yao, K. Kawabata +18 more
2021iScience9 citations Open access
Semantic Scholar
DT2216, a BCL-XL Proteolysis Targeting Chimera (PROTAC), Is a Potent Anti T-Cell Lymphoma Agent That Does Not Induce Significant Thrombocytopenia
Yonghan He, R. Koch, Vivekananda Budamagunta, D. Lv +6 more
2019Blood8 citations Open access
Semantic Scholar
Preliminary Results of the Stapled Peptide ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Two Phase IIa Dose Expansion Cohorts in Relapsed/Refractory TP53 Wild-Type Peripheral T-Cell Lymphoma
A. Shustov, S. Horwitz, J. Zain, M. Patel +13 more
2018Blood8 citations
Semantic Scholar

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