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F. Fleischer · SciRah

Researcher profile · Semantic Scholar

F. Fleischer

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F. Fleischer — researcher profile on SciRah

h-index: 10
Works: 24
Citations: 433

Most-cited papers

A phase II trial to assess efficacy and safety of afatinib in extensively pretreated patients with HER2-negative metastatic breast cancer
M. Schuler, A. Awada, P. Harter, J. Canon +16 more
2012Breast Cancer Research and Treatment90 citations Open access
Semantic Scholar
A randomised phase II trial of the Polo-like kinase inhibitor BI 2536 in chemo-naïve patients with unresectable exocrine adenocarcinoma of the pancreas – a study within the Central European Society Anticancer Drug Research (CESAR) collaborative network
K. Mross, Christian Dittrich, W. Aulitzky, D. Strumberg +7 more
2012British Journal of Cancer85 citations Open access
Semantic Scholar
A statistical model for the dependence between progression‐free survival and overall survival
F. Fleischer, B. Gaschler-Markefski, E. Bluhmki
2009Statistics in Medicine67 citations
Semantic Scholar
A randomized, open‐label, phase I/II trial to investigate the maximum tolerated dose of the Polo‐like kinase inhibitor BI 2536 in elderly patients with refractory/relapsed acute myeloid leukaemia
C. Müller-Tidow, G. Bug, M. Lübbert, A. Krämer +11 more
2013British Journal of Haematology46 citations
Semantic Scholar
Phase I study of pulsatile 3-day administration of afatinib (BIBW 2992) in combination with docetaxel in advanced solid tumors
A. Awada, H. Dumez, A. Hendlisz, P. Wolter +6 more
2012Investigational new drugs32 citations Open access
Semantic Scholar
Phase I/II Study of BI 6727 (volasertib), An Intravenous Polo-Like Kinase-1 (Plk1) Inhibitor, In Patients with Acute Myeloid Leukemia (AML): Results of the Dose Finding for BI 6727 In Combination with Low-Dose Cytarabine
G. Bug, R. Schlenk, C. Müller-Tidow, M. Lübbert +5 more
201020 citations
Semantic Scholar
Testing randomized software by means of statistical hypothesis tests
Ralph Guderlei, Johannes Mayer, Christoph Schneckenburger, F. Fleischer
2007International Workshop on Software Quality Assurance16 citations
Semantic Scholar
A phase I dose-escalation study of BI 811283, an Aurora B inhibitor, administered every three weeks in patients with advanced solid tumors.
K. Mross, M. Scheulen, A. Frost, D. Scharr +6 more
201012 citations
Semantic Scholar
Phase I trial assessing safety and pharmacokinetics of afatinib (BIBW 2992) with intravenous weekly vinorelbine in advanced solid tumors.
R. Bahleda, J. Soria, Y. Bergé, C. Massard +7 more
2011Journal of Clinical Oncology11 citations
Semantic Scholar
How is retrospective independent review influenced by investigator‐introduced informative censoring: A quantitative approach
F. Fleischer, B. Gaschler-Markefski, E. Bluhmki
2011Statistics in Medicine11 citations
Semantic Scholar
Bayesian Phase II optimization for time-to-event data based on historical information
A. Bertsche, F. Fleischer, J. Beyersmann, G. Nehmiz
2019Statistical Methods in Medical Research9 citations Open access
Semantic Scholar
A comparison of group sequential and fixed sample size designs for bioequivalence trials with highly variable drugs
Sophie I. E. Knahl, B. Lang, F. Fleischer, M. Kieser
2018European Journal of Clinical Pharmacology8 citations
Semantic Scholar
Bayesian MCPMod
F. Fleischer, Sebastian Bossert, Q. Deng, C. Loley +1 more
2022Pharmaceutical statistics6 citations
Semantic Scholar
SAT0147 Safety and Efficacy of BI 655064, An Antagonistic Anti-CD40 Antibody in Rheumatoid Arthritis (RA) Patients
S. Daniluk, R. Ptaszyński, U. Mueller-Ladner, A. Petříková +13 more
20165 citations
Semantic Scholar
Polo-Like Kinase-1 (Plk-1) Inhibitor BI 2536 Induces Mitotic Arrest and Apoptosis in Vivo: First Demonstration of Target Inhibition in the Bone Marrow of AML Patients
Kang-Hun Lee, R. Schlenk, G. Bug, C. Müller-Tidow +7 more
20085 citations
Semantic Scholar
Bayesian hierarchical model for dose-finding trial incorporating historical data
Linxi Han, Qiqi Deng, Zhangyi He, F. Fleischer +1 more
2022medRxiv4 citations Open access
Semantic Scholar
BIBW 2992, a Novel Irreversible EGFR/HER1 and HER2 Tyrosine Kinase Inhibitor for the Treatment of Patients with HER2-Negative Metastatic Breast Cancer after Failure of No More Than Two Prior Chemotherapies.
N. Harbeck, M. Schmidt, P. Harter, K. Possinger +18 more
20094 citations
Semantic Scholar
Multi-state Models Used in Oncology Trials
B. Gaschler-Markefski, Karin Schiefele, J. Hocke, F. Fleischer
20141 citations
Semantic Scholar
Commentary: analyzing binary data using MCPMod when zero counts are expected
Yi Liu, Sebastian Bossert, Rui Wu, D. Roy +2 more
20220 citations
Semantic Scholar
Efficacy-Driven Dose Finding with Toxicity Control in Phase I Oncology Studies
Qingyang Liu, J. Geng, F. Fleischer, Q. Deng
2021Statistics in Biosciences0 citations
Semantic Scholar
Comments on ‘Multiplicity adjustments in testing for bioequivalence’
B. Lang, F. Fleischer
2016Statistics in Medicine0 citations
Semantic Scholar
Evaluating Overall Survival in Oncology Trials with Subsequent Therapies: A Methodological Review and Application in Non-Small Cell Lung Cancer
L. Jonsson, F. Fleischer, E. Bluhmki, I. Griebsch
20130 citations Open access
Semantic Scholar
Structural Failure Time Modeling of Overall Survival Effects in Oncology Trials with Subsequent Therapies
L. Jonsson, F. Fleischer, E. Bluhmki, I. Griebsch
20130 citations Open access
Semantic Scholar
Successful transformations?
M. Myant, F. Fleischer, K. Hornschild, Růžena Vintrová +2 more
19960 citations
Semantic Scholar

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