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K. Possinger · SciRah

Researcher profile · Semantic Scholar

K. Possinger

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K. Possinger — researcher profile on SciRah

h-index: 50
Works: 309
Citations: 9,016

Most-cited papers

Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-In-Cachexia-Study-Group.
F. Strasser, D. Luftner, K. Possinger, G. Ernst +6 more
2006Journal of Clinical Oncology314 citations
Semantic Scholar
Double-blind, randomized placebo controlled trial of fulvestrant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: results from EFECT.
S. Chia, W. Gradishar, L. Mauriac, J. Bines +12 more
2008Journal of Clinical Oncology301 citations
Semantic Scholar
Biomarkers of depression in cancer patients
C. Jehn, D. Kuehnhardt, A. Bartholomae, S. Pfeiffer +5 more
2006Cancer141 citations Open access
Semantic Scholar
Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer.
Hong-Yu Liu, C. Zang, A. Emde, M. Planas-Silva +6 more
2008European Journal of Pharmacology128 citations
Semantic Scholar
13th st. Gallen international breast cancer conference 2013: primary therapy of early breast cancer evidence, controversies, consensus - opinion of a german team of experts (zurich 2013).
M. Untch, B. Gerber, N. Harbeck, C. Jackisch +27 more
2013Breast Care125 citations Open access
Semantic Scholar
Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro.
Hong-Yu Liu, C. Scholz, C. Zang, J. Schefe +5 more
2012Anticancer Research103 citations
Semantic Scholar
A phase II trial to assess efficacy and safety of afatinib in extensively pretreated patients with HER2-negative metastatic breast cancer
M. Schuler, A. Awada, P. Harter, J. Canon +16 more
2012Breast Cancer Research and Treatment90 citations Open access
Semantic Scholar
Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma
U. Heider, M. Kaiser, J. Sterz, I. Zavrski +5 more
2006European Journal of Haematology85 citations
Semantic Scholar
Leuprorelin acetate every-3-months depot versus cyclophosphamide, methotrexate, and fluorouracil as adjuvant treatment in premenopausal patients with node-positive breast cancer: the TABLE study.
P. Schmid, M. Untch, V. Kosse, G. Bondar +7 more
2007Journal of Clinical Oncology83 citations Open access
Semantic Scholar
Second consensus on medical treatment of metastatic breast cancer.
S. Beslija, J. Bonneterre, H. Burstein, V. Cocquyt +19 more
2007Annals of Oncology77 citations Open access
Semantic Scholar
Association of IL-6, Hypothalamus-Pituitary-Adrenal Axis Function, and Depression in Patients With Cancer
C. Jehn, Dagmar Kühnhardt, A. Bartholomae, S. Pfeiffer +4 more
2010Integrative Cancer Therapies69 citations Open access
Semantic Scholar
Influence of age, performance status, cancer activity, and IL-6 on anxiety and depression in patients with metastatic breast cancer
C. Jehn, B. Flath, A. Strux, M. Krebs +3 more
2012Breast Cancer Research and Treatment65 citations
Semantic Scholar
Anionic Polysaccharides From Phototrophic Microorganisms Exhibit Antiviral Activities to Vaccinia Virus
A. Radonic, S. Thulke, J. Achenbach, A. Kurth +5 more
201062 citations Open access
Semantic Scholar
Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARα/γ ligand TZD18
Hong-Yu Liu, C. Zang, M. Fenner, Da-Chuan Liu +3 more
200658 citations Open access
Semantic Scholar
Up-front tandem high-dose chemotherapy compared with standard chemotherapy with doxorubicin and paclitaxel in metastatic breast cancer: results of a randomized trial.
P. Schmid, W. Schippinger, T. Nitsch, G. Huebner +5 more
2005Journal of Clinical Oncology56 citations
Semantic Scholar
The effect of induced hyperthermia on the immune system.
A. Dieing, O. Ahlers, B. Hildebrandt, T. Kerner +3 more
2007Progress in Brain Research50 citations
Semantic Scholar
Inhibition of pan-class I phosphatidyl-inositol-3-kinase by NVP-BKM120 effectively blocks proliferation and induces cell death in diffuse large B-cell lymphoma
C. Zang, J. Eucker, Hong-Yu Liu, A. Coordes +3 more
2014Leukemia and Lymphoma46 citations
Semantic Scholar
An internally and externally validated prognostic score for metastatic breast cancer: analysis of 2269 patients.
A. Regierer, R. Wolters, M. Ufen, A. Weigel +6 more
2014Annals of Oncology40 citations Open access
Semantic Scholar
The amino-terminal propeptide (PINP) of type I collagen is a clinically valid indicator of bone turnover and extent of metastatic spread in osseous metastatic breast cancer.
D. Pollmann, S. Siepmann, R. Geppert, K. Wernecke +2 more
2007Anticancer Research39 citations
Semantic Scholar
Metastatic breast cancer: are we treating the same patients as in the past?
M. Ufen, C. Köhne, M. Wischneswky, R. Wolters +5 more
2014Annals of Oncology38 citations Open access
Semantic Scholar
Concurrent inhibition of PI3-kinase and mTOR induces cell death in diffuse large B cell lymphomas, a mechanism involving down regulation of Mcl-1.
C. Zang, J. Eucker, Hong-Yu Liu, Anja Müller +2 more
2013Cancer Letters37 citations
Semantic Scholar
Dual PPARα/γ Ligand TZD18 Either Alone or in Combination with Imatinib Inhibits Proliferation and Induces Apoptosis of Human CML Cell Lines
C. Zang, Hong-Yu Liu, M. Waechter, J. Eucker +4 more
2006Cell Cycle36 citations Open access
Semantic Scholar
Influence of CYP2D6-genotype on tamoxifen efficacy in advanced breast cancer
J. Karle, Juliane Bolbrinker, S. Vogl, R. Kreutz +5 more
2013Breast Cancer Research and Treatment33 citations
Semantic Scholar
Therapeutic implication of BAL in patients with neutropenia
D. Kuehnhardt, Manja Hannemann, B. Schmidt, U. Heider +2 more
2009Annals of Hematology31 citations Open access
Semantic Scholar
Simultaneous Inhibition of Estrogen Receptor and the HER2 Pathway in Breast Cancer: Effects of HER2 Abundance.
A. Emde, G. Mahlknecht, K. Maslak, B. Ribba +3 more
2011Translational Oncology30 citations Open access
Semantic Scholar
Cost-utility analysis for advanced breast cancer therapy in Germany: results of the fulvestrant sequencing model
M. Lux, M. Hartmann, C. Jackisch, G. Raab +4 more
2009Breast Cancer Research and Treatment28 citations
Semantic Scholar
Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18.
Hong-Yu Liu, C. Zang, M. Fenner, Da-Chuan Liu +3 more
2006Blood27 citations
Semantic Scholar
Breast Cancer-Associated Thrombotic Microangiopathy
A. Regierer, D. Kuehnhardt, C. Schulz, B. Flath +4 more
2011Breast Care26 citations Open access
Semantic Scholar
Induction of endoplasmic reticulum stress response by TZD18, a novel dual ligand for peroxisome proliferator-activated receptor α/γ, in human breast cancer cells
C. Zang, Hong-Yu Liu, Janina Bertz, K. Possinger +3 more
2009Molecular Cancer Therapeutics26 citations Open access
Semantic Scholar
Cost-Effectiveness Analysis of Anastrozole versus Tamoxifen in Adjuvant Therapy for Early-Stage Breast Cancer – A Health-Economic Analysis Based on the 100-Month Analysis of the ATAC Trial and the German Health System
M. Lux, A. Wöckel, Á. Benedict, S. Buchholz +13 more
2010Oncology Research and Treatment23 citations Open access
Semantic Scholar
The mTOR inhibitor RAD001 sensitizes tumor cells to the cytotoxic effect of carboplatin in breast cancer in vitro.
Hong-Yu Liu, C. Zang, J. Schefe, S. Schwarzlose-Schwarck +6 more
2011Anticancer Research22 citations
Semantic Scholar
Primary Tumor Excision in Stage IV Breast Cancer at Diagnosis without Influence on Survival: A Retrospective Analysis and Review of the Literature
M. Rosche, A. Regierer, S. Schwarzlose-Schwarck, A. Weigel +5 more
2011Oncology Research and Treatment22 citations
Semantic Scholar
Randomized trial of high-dose adjuvant chemotherapy with autologous hematopoietic stem-cell support versus standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: overall survival after 6 years of follow-up.
A. Zander, C. Schmoor, N. Kroger, W. Krüger +11 more
2008Annals of Oncology22 citations Open access
Semantic Scholar
The mTOR inhibitor everolimus in combination with carboplatin in metastatic breast cancer--a phase I trial.
S. Schwarzlose-Schwarck, C. Scholz, A. Regierer, P. Martus +8 more
2012Anticancer Research21 citations
Semantic Scholar
Contrast-Enhancing Meningeal Lesions Are Associated with Longer Survival in Breast Cancer-Related Leptomeningeal Metastasis
A. Regierer, A. Stroux, Dagmar Kühnhardt, A. Dieing +4 more
2008Breast Care14 citations Open access
Semantic Scholar
Gemcitabine as prolonged infusion and vinorelbine in anthracycline and/or taxane pretreated metastatic breast cancer: a phase II study
P. Schmid, V. Heilmann, C. Schulz, A. Dieing +5 more
2005Journal of Cancer Research and Clinical Oncology14 citations Open access
Semantic Scholar
Tumor Cell-selective Synergism of TRAIL- and ATRA-induced Cytotoxicity in Breast Cancer Cells.
A. Reinhardt, Hong-Yu Liu, Yun-Xia Ma, Yong’an Zhou +4 more
2018Anticancer Research12 citations Open access
Semantic Scholar
Effect of the tyrosine kinase inhibitor lapatinib on CUB-domain containing protein (CDCP1)-mediated breast cancer cell survival and migration.
J. Seidel, K. Kunc, K. Possinger, C. Jehn +1 more
2011Biochemical and Biophysical Research Communications - BBRC11 citations
Semantic Scholar
Synergistic Interaction of the Histone Deacetylase Inhibitor SAHA with the Proteasome Inhibitor Bortezomib in Mantle Cell Lymphoma.
U. Heider, M. Kaiser, I. Zavrski, J. Sterz +7 more
200611 citations
Semantic Scholar
Interferon-alpha therapy for chronic myeloid leukemia during pregnancy.
A. Regierer, C. Schulz, D. Kuehnhardt, B. Flath +1 more
2006American journal of hematology/oncology11 citations
Semantic Scholar
Compound 48, a novel dual PPAR alpha/gamma ligand, inhibits the growth of human CML cell lines and enhances the anticancer-effects of imatinib.
Janina Bertz, C. Zang, Hong-Yu Liu, M. Wächter +3 more
2009Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis9 citations
Semantic Scholar
Treatment of Bortezomib Increases Osteoblast Function in Patients with Multiple Myeloma.
U. Heider, M. Kaiser, Christian A. Müller, C. Schulz +7 more
20058 citations
Semantic Scholar
[Chemotherapy of metastasized breast carcinoma].
K. Possinger, H. Sauer, W. Wilmanns
2008Deutsche Medizinische Wochenschrift7 citations
Semantic Scholar
Combination of fulvestrant and lapatinib in non-HER2-overexpressing and adriamycin-resistant breast cancer cell lines
A. Emde, K. Maslak, Hong-Yu Liu, A. Reles +2 more
20077 citations
Semantic Scholar
ACT-FASTER, a Prospective Cohort Study Exploring Treatment Patterns with Fulvestrant and Exemestane in Postmenopausal Patients with Advanced Hormone Receptor-Positive Breast Cancer under Real-Life Conditions in Germany
N. Maass, H. Ostermann, K. Possinger, P. Klein +3 more
2019Breast Care4 citations Open access
Semantic Scholar
Pretreatment of BMSCs with TZD solution decreases the proliferation rate of MCF-7 cells by reducing FGF4 protein expression
B. Khoo, Kalpanah Nadarajan, S. Shim, N. Miswan +3 more
2016Molecular Medicine Reports4 citations Open access
Semantic Scholar
Individualisierte Therapie des Mammakarzinoms
J. Eucker, K. Possinger
2011Deutsche Medizinische Wochenschrift4 citations
Semantic Scholar
An open-label, dose-escalating study of Maxy-G34, a novel potent, long-acting Pegylated G-CSF, compared with pegfilgrastim (PF) for the treatment of chemotherapy induced neutropenia (CIN).
L. Schwartzberg, S. L. Sankar, D. Apt, E. Goldstein +6 more
2009Journal of Clinical Oncology4 citations
Semantic Scholar
BIBW 2992, a Novel Irreversible EGFR/HER1 and HER2 Tyrosine Kinase Inhibitor for the Treatment of Patients with HER2-Negative Metastatic Breast Cancer after Failure of No More Than Two Prior Chemotherapies.
N. Harbeck, M. Schmidt, P. Harter, K. Possinger +18 more
20094 citations
Semantic Scholar
Cisplatin Plus Ifosfamide with/without Etoposide as Salvage Treatment in Heavily-pre-treated Patients with Metastatic Breast Cancer.
P. Habbel, A. Kurreck, C. Schulz, A. Regierer +5 more
2015Anticancer Research3 citations
Semantic Scholar

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