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A. Postlethwaite · SciRah

Researcher profile · Semantic Scholar

A. Postlethwaite

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A. Postlethwaite — researcher profile on SciRah

h-index: 47
Works: 165
Citations: 8,515

Most-cited papers

Steroidogenesis in the skin: implications for local immune functions
A. Słominski, Bazej Zbytek, G. Nikolakis, P. Manna +7 more
2013Journal of Steroid Biochemistry and Molecular Biology358 citations Open access
Semantic Scholar
RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20‐hydroxy‐ and 20,23‐dihydroxyvitamin D
A. Słominski, Tae-Kang Kim, Y. Takeda, Z. Janjetović +7 more
2014The FASEB Journal271 citations Open access
Semantic Scholar
In vivo evidence for a novel pathway of vitamin D3 metabolism initiated by P450scc and modified by CYP27B1
A. Słominski, Tae-Kang Kim, Haleem Z. Shehabi, I. Semak +10 more
2012The FASEB Journal264 citations Open access
Semantic Scholar
Pathogenesis of Systemic Sclerosis
D. Pattanaik, Monica L. Brown, B. Postlethwaite, A. Postlethwaite
2015Frontiers in Immunology259 citations Open access
Semantic Scholar
Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland
A. Słominski, Tae-Kang Kim, Wei Li, A. Postlethwaite +3 more
2015Scientific Reports222 citations Open access
Semantic Scholar
Cellular origins of fibroblasts: possible implications for organ fibrosis in systemic sclerosis
A. Postlethwaite, H. Shigemitsu, S. Kanangat
2004Current Opinion in Rheumatology178 citations
Semantic Scholar
The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions
A. Słominski, Tae-Kang Kim, Wei Li, A. Yi +2 more
2013Journal of Steroid Biochemistry and Molecular Biology161 citations Open access
Semantic Scholar
Elevated Serum Levels of Arachidonoyl-lysophosphatidic Acid and Sphingosine 1-Phosphate in Systemic Sclerosis
A. Tokumura, L. Carbone, Yasuko Yoshioka, Jun-ichi Morishige +3 more
2009International Journal of Medical Sciences138 citations Open access
Semantic Scholar
Extra-adrenal glucocorticoid biosynthesis: Implications for autoimmune and inflammatory disorders.
R. Slominski, R. Tuckey, P. Manna, A. Jetten +3 more
2020Genes and Immunity131 citations Open access
Semantic Scholar
Course of Modified Rodnan Skin Score in Systemic Sclerosis Clinical Trials: Analysis of 3 Large Multicenter, Randomized Clinical Trials
Sogol S. Amjadi, P. Maranian, D. Furst, P. Clements +4 more
2009Arthritis & Rheumatism121 citations Open access
Semantic Scholar
Vascular involvement in systemic sclerosis (scleroderma)
D. Pattanaik, Monica L. Brown, A. Postlethwaite
2011Journal of Inflammation Research117 citations Open access
Semantic Scholar
A multicenter, randomized, double-blind, placebo-controlled trial of oral type I collagen treatment in patients with diffuse cutaneous systemic sclerosis: I. oral type I collagen does not improve skin in all patients, but may improve skin in late-phase disease.
A. Postlethwaite, Weng-Kee Wong, P. Clements, S. Chatterjee +16 more
2008Arthritis & Rheumatism102 citations Open access
Semantic Scholar
20S-hydroxyvitamin D3, noncalcemic product of CYP11A1 action on vitamin D3, exhibits potent antifibrogenic activity in vivo.
A. Słominski, Z. Janjetović, R. Tuckey, Minh N. Nguyen +7 more
2013Journal of Clinical Endocrinology and Metabolism87 citations Open access
Semantic Scholar
Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols
A. Słominski, Tae-Kang Kim, J. Hobrath, Z. Janjetović +7 more
2017Scientific Reports78 citations Open access
Semantic Scholar
20-Hydroxyvitamin D3 Inhibits Proliferation of Cancer Cells with High Efficacy while Being Non-toxic
Jin Wang, A. Słominski, R. Tuckey, Z. Janjetović +5 more
2012Anticancer Research77 citations
Semantic Scholar
Platelet contributions to the pathogenesis of systemic sclerosis
A. Postlethwaite, T. Chiang
2007Current Opinion in Rheumatology73 citations
Semantic Scholar
Novel vitamin D photoproducts and their precursors in the skin
A. Słominski, Tae-Kang Kim, M. Żmijewski, Z. Janjetović +8 more
2013Dermato-Endocrinology72 citations Open access
Semantic Scholar
Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections
S. Kanangat, A. Postlethwaite, K. Hasty, A. Kang +3 more
2006Arthritis Research & Therapy69 citations Open access
Semantic Scholar
New insights into the mechanism of fibroblast to myofibroblast transformation and associated pathologies.
M. Watsky, K. Weber, Yao Sun, A. Postlethwaite
2010International Review of Cell and Molecular Biology65 citations
Semantic Scholar
Association between population density and infection rate suggests the importance of social distancing and travel restriction in reducing the COVID-19 pandemic
He-Liang Yin, T. Sun, Lan Yao, Y. Jiao +7 more
2020Environmental science and pollution research international61 citations Open access
Semantic Scholar
Reliability, validity, and minimally important differences of the SF-6D in systemic sclerosis
D. Khanna, D. Furst, Weng-Kee Wong, J. Tsevat +6 more
2007Quality of Life Research60 citations
Semantic Scholar
Novel Vitamin D Analogs as Potential Therapeutics: The Metabolism, Toxicity Profiling, and Antiproliferative Activity
Jian-Jun Chen, Jin Wang, Tae-Kang Kim, Elaine W. Tieu +8 more
2014Anticancer Research57 citations
Semantic Scholar
Characterization of Serotonin and N-acetylserotonin Systems in the Human Epidermis and Skin Cells
A. Słominski, Tae-Kang Kim, K. Kleszczyński, I. Semak +9 more
2019Journal of Pineal Research55 citations Open access
Semantic Scholar
Chance, genetics, and the heterogeneity of disease and pathogenesis in systemic lupus erythematosus
T. Marion, A. Postlethwaite
2014Seminars in Immunopathology55 citations
Semantic Scholar
Sensitivity to change of the modified Rodnan skin score in diffuse systemic sclerosis--assessment of individual body sites in two large randomized controlled trials.
Marian Kaldas, P. Khanna, D. Furst, P. Clements +4 more
2009Rheumatology50 citations Open access
Semantic Scholar
Dual-specificity phosphatases 2: surprising positive effect at the molecular level and a potential biomarker of diseases
W. Wei, Y. Jiao, A. Postlethwaite, J. Stuart +3 more
2012Genes and Immunity49 citations Open access
Semantic Scholar
Novel Vitamin D Analogues 17,20S(OH)2pD and 17,20R(OH)2pD are Noncalcemic and Exhibit Antifibrotic Activity
A. Słominski, Wei Li, S. Bhattacharya, R. Smith +8 more
2011Journal of Investigative Dermatology48 citations Open access
Semantic Scholar
Rheumatoid arthritis and periodontal disease: What are the similarities and differences?
Rong-Bing Li, Cheng Tian, A. Postlethwaite, Y. Jiao +5 more
2017International Journal of Rheumatic Diseases45 citations
Semantic Scholar
The scar neovasculature after myocardial infarction in rats.
Bin Wang, R. Ansari, Yao Sun, A. Postlethwaite +2 more
2005American Journal of Physiology. Heart and Circulatory Physiology43 citations
Semantic Scholar
Investigation of 20S-hydroxyvitamin D3 analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities
Zong-Tao Lin, S. R. Marepally, Emily S. Y. Goh, C. Cheng +9 more
2018Scientific Reports42 citations Open access
Semantic Scholar
Modulation of virulence gene expression in Staphylococcus aureus by interleukin-1beta: novel implications in bacterial pathogenesis.
S. Kanangat, A. Postlethwaite, S. Cholera, Latonya Williams +1 more
2007Microbes and infection36 citations Open access
Semantic Scholar
Modulation of TNF-α Gene Expression by IFN-γ and Pamidronate in Murine Macrophages: Regulation by STAT1-Dependent Pathways1
K. Takagi, M. Takagi, S. Kanangat, K. Warrington +2 more
2005Journal of Immunology33 citations Open access
Semantic Scholar
Novel functions of intracellular IL-1ra in human dermal fibroblasts: implications in the pathogenesis of fibrosis.
S. Kanangat, A. Postlethwaite, G. Higgins, K. Hasty
2006Journal of Investigative Dermatology32 citations Open access
Semantic Scholar
Increase in platelet non-integrin type I collagen receptor in patients with systemic sclerosis.
T. Chiang, H. Takayama, A. Postlethwaite
2006Thrombosis Research31 citations
Semantic Scholar
Skin under the sun: when melanin pigment meets vitamin D.
A. Słominski, A. Postlethwaite
2015Endocrinology29 citations Open access
Semantic Scholar
A role for lysophosphatidic acid and sphingosine 1-phosphate in the pathogenesis of systemic sclerosis.
D. Pattanaik, A. Postlethwaite
2010Discover medicine29 citations
Semantic Scholar
Gender and ethnicity differences in patients with diffuse systemic sclerosis--analysis from three large randomized clinical trials.
M. Nashid, P. Khanna, D. Furst, P. Clements +7 more
2011Rheumatology26 citations Open access
Semantic Scholar
Characterisation of the immune response to type I collagen in scleroderma
K. Warrington, U. Nair, L. Carbone, A. Kang +1 more
2006Arthritis Research & Therapy26 citations Open access
Semantic Scholar
Lysophosphatidic acid-activated Cl- current activity in human systemic sclerosis skin fibroblasts.
Zhaohong Yin, L. Carbone, M. Gotoh, A. Postlethwaite +4 more
2010Rheumatology25 citations Open access
Semantic Scholar
1α,20S-Dihydroxyvitamin D3 Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis
Zong-Tao Lin, Hao Chen, A. Belorusova, J. Bollinger +10 more
2017Scientific Reports24 citations Open access
Semantic Scholar
20S-Hydroxyvitamin D3, a Secosteroid Produced in Humans, Is Anti-Inflammatory and Inhibits Murine Autoimmune Arthritis
A. Postlethwaite, R. Tuckey, Tae-Kang Kim, Wei Li +4 more
2021Frontiers in Immunology22 citations Open access
Semantic Scholar
Differences between Mice and Humans in Regulation and the Molecular Network of Collagen, Type III, Alpha-1 at the Gene Expression Level: Obstacles that Translational Research Must Overcome
Lishi Wang, Hong-Chao Liu, Y. Jiao, Erjian Wang +4 more
2015International Journal of Molecular Sciences22 citations Open access
Semantic Scholar
Chemical Synthesis and Biological Activities of 20S,24S/R-Dihydroxyvitamin D3 Epimers and Their 1α-Hydroxyl Derivatives
Zong-Tao Lin, S. R. Marepally, Dejian Ma, L. Myers +8 more
2015Journal of Medicinal Chemistry22 citations Open access
Semantic Scholar
Antifibrogenic activities of CYP11A1-derived vitamin D3-hydroxyderivatives are dependent on RORγ.
Z. Janjetović, A. Postlethwaite, H. Kang, Tae-Kang Kim +5 more
2020Endocrinology20 citations Open access
Semantic Scholar
Characterization of T cell phenotype and function in a double transgenic (collagen-specific TCR/HLA-DR1) humanized model of arthritis
B. Tang, Seunghyun Kim, Sarah A. Hammond, David L Cullins +6 more
2014Arthritis Research & Therapy18 citations Open access
Semantic Scholar
Modulation of TNF-alpha gene expression by IFN-gamma and pamidronate in murine macrophages: regulation by STAT1-dependent pathways.
K. Takagi, M. Takagi, S. Kanangat, K. Warrington +2 more
2005Journal of Immunology17 citations
Semantic Scholar
Toward a broader understanding of aldosterone in congestive heart failure
K. Weber, Yao Sun, L. Wodi, A. Munir +5 more
2003Journal of the Renin-Angiotensin-Aldosterone System17 citations Open access
Semantic Scholar
Does incorporation of aids and devices make a difference in the score of the health assessment questionnaire-disability index? Analysis from a scleroderma clinical trial.
D. Khanna, P. Clements, A. Postlethwaite, D. Furst
2008Journal of Rheumatology16 citations
Semantic Scholar
A Retrospective Analysis of Corticosteroid Utilization Before Initiation of Biologic DMARDs Among Patients with Rheumatoid Arthritis in the United States
C. Spivey, J. Griffith, Cameron M. Kaplan, A. Postlethwaite +2 more
2018Rheumatology and Therapy15 citations Open access
Semantic Scholar
1,25-Dihydroxyvitamin D3 and 20-Hydroxyvitamin D3 Upregulate LAIR-1 and Attenuate Collagen Induced Arthritis
L. Myers, Michael L. Winstead, John D. Kee, Jeoungeun J. Park +10 more
2021International Journal of Molecular Sciences13 citations Open access
Semantic Scholar

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