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K. Kleszczyński · SciRah

Researcher profile · Semantic Scholar

K. Kleszczyński

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K. Kleszczyński — researcher profile on SciRah

h-index: 31
Works: 77
Citations: 2,663

Most-cited papers

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR‐induced depletion, and protects against the formation of DNA damage (8‐hydroxy‐2'‐deoxyguanosine) in ex vivo human skin
T. Fischer, K. Kleszczyński, Lena H. Hardkop, N. Kruse +1 more
2013Journal of Pineal Research308 citations
Semantic Scholar
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells
Tae-Kang Kim, K. Kleszczyński, Z. Janjetović, T. Sweatman +5 more
2013The FASEB Journal154 citations Open access
Semantic Scholar
Local Melatoninergic System as the Protector of Skin Integrity
A. Słominski, K. Kleszczyński, I. Semak, Z. Janjetović +5 more
2014International Journal of Molecular Sciences134 citations Open access
Semantic Scholar
Melatonin enhances mitochondrial ATP synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2‐related factor 2 resulting in activation of phase‐2 antioxidant enzymes (γ‐GCS, HO‐1, NQO1) in ultraviolet radiation‐treated normal human epidermal keratin
K. Kleszczyński, D. Zillikens, T. Fischer
2016Journal of Pineal Research126 citations
Semantic Scholar
Metabolism of melatonin in the skin: why is it important?
A. Słomiński, I. Semak, T. Fischer, Tae-Kang Kim +3 more
2017Experimental Dermatology115 citations Open access
Semantic Scholar
Protective Role of Melatonin and Its Metabolites in Skin Aging
G. Bocheva, R. Slominski, Z. Janjetović, Tae-Kang Kim +5 more
2022International Journal of Molecular Sciences114 citations Open access
Semantic Scholar
Analysis of structure-cytotoxicity in vitro relationship (SAR) for perfluorinated carboxylic acids.
K. Kleszczyński, Paweł Gardzielewski, E. Mulkiewicz, P. Stepnowski +1 more
2007Toxicology in Vitro92 citations
Semantic Scholar
Evaluation of the acute toxicity of perfluorinated carboxylic acids using eukaryotic cell lines, bacteria and enzymatic assays.
Ewa Mulkiewicz, B. Jastorff, A. Składanowski, K. Kleszczyński +1 more
2007Environmental Toxicology and Pharmacology83 citations
Semantic Scholar
AMP deaminase in vitro inhibition by xenobiotics A potential molecular method for risk assessment of synthetic nitro- and polycyclic musks, imidazolium ionic liquids and N-glucopyranosyl ammonium salts.
A. Składanowski, P. Stepnowski, K. Kleszczyński, B. Dmochowska
2005Environmental Toxicology and Pharmacology76 citations
Semantic Scholar
Melatonin and human skin aging
K. Kleszczyński, T. Fischer
2012Dermato-Endocrinology74 citations Open access
Semantic Scholar
Dual sources of melatonin and evidence for different primary functions
R. Reiter, Ramaswamy Sharma, D. Tan, Luiz Gustavo de Almieda Chuffa +4 more
2024Frontiers in Endocrinology71 citations Open access
Semantic Scholar
Mechanism of cytotoxic action of perfluorinated acids. I. alteration in plasma membrane potential and intracellular pH level.
K. Kleszczyński, A. Składanowski
2009Toxicology and Applied Pharmacology64 citations
Semantic Scholar
Evolutionary formation of melatonin and vitamin D in early life forms: insects take centre stage
Tae-Kang Kim, R. Slominski, Elżbieta Pyza, K. Kleszczyński +4 more
2024Biological Reviews of The Cambridge Philosophical Society62 citations Open access
Semantic Scholar
Melatonin and Its Metabolites Can Serve as Agonists on the Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor Gamma
A. Słomiński, Tae-Kang Kim, R. Slominski, Yu-Wei Song +11 more
2023International Journal of Molecular Sciences62 citations Open access
Semantic Scholar
Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: role of Nrf2-dependent gene expression and antioxidant enzymes.
K. Kleszczyński, I. Ernst, A. E. Wagner, N. Kruse +3 more
2013Pharmacological Research62 citations
Semantic Scholar
Mechanism of cytotoxic action of perfluorinated acids II. Disruption of mitochondrial bioenergetics.
K. Kleszczyński, P. Stepnowski, A. Składanowski
2009Toxicology and Applied Pharmacology56 citations
Semantic Scholar
Characterization of Serotonin and N-acetylserotonin Systems in the Human Epidermis and Skin Cells
A. Słominski, Tae-Kang Kim, K. Kleszczyński, I. Semak +9 more
2019Journal of Pineal Research55 citations Open access
Semantic Scholar
Endocrine Controls of Skin Aging.
M. Böhm, A. Stegemann, Ralf Paus, K. Kleszczyński +3 more
2025Endocrine reviews51 citations Open access
Semantic Scholar
Clinical Trials for Use of Melatonin to Fight against COVID-19 Are Urgently Needed
K. Kleszczyński, A. Słominski, K. Steinbrink, R. Reiter
2020Nutrients51 citations Open access
Semantic Scholar
Melatonin compensates silencing of heat shock protein 70 and suppresses ultraviolet radiation‐induced inflammation in human skin ex vivo and cultured keratinocytes
K. Kleszczyński, Stephanie Zwicker, S. Tukaj, M. Kasperkiewicz +3 more
2015Journal of Pineal Research47 citations
Semantic Scholar
Aberrant Expression and Secretion of Heat Shock Protein 90 in Patients with Bullous Pemphigoid
S. Tukaj, K. Kleszczyński, K. Vafia, S. Groth +7 more
2013PLoS ONE47 citations Open access
Semantic Scholar
Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells
K. Kleszczyński, Bernadetta Bilska, A. Stegemann, D. Flis +6 more
2018International Journal of Molecular Sciences46 citations Open access
Semantic Scholar
Melatonin prevents ultraviolet radiation‐induced alterations in plasma membrane potential and intracellular pH in human keratinocytes
K. Kleszczyński, S. Tukaj, N. Kruse, D. Zillikens +1 more
2013Journal of Pineal Research42 citations
Semantic Scholar
Melatonin: A Potential Regulator of DNA Methylation
K. Linowiecka, A. Słominski, R. Reiter, M. Böhm +3 more
2023Antioxidants41 citations Open access
Semantic Scholar
Melatonin exerts oncostatic capacity and decreases melanogenesis in human MNT-1 melanoma cells
K. Kleszczyński, Tae-Kang Kim, Bernadetta Bilska, M. Sarna +7 more
2019Journal of Pineal Research41 citations Open access
Semantic Scholar
Differential effects of melatonin as a broad range UV-damage preventive dermato-endocrine regulator
K. Kleszczyński, Lena H. Hardkop, T. Fischer
2011Dermato-Endocrinology37 citations Open access
Semantic Scholar
Melatonin and the Skin: Current Progress and Perspectives for Human Health
A. Słomiński, Tae-Kang Kim, Z. Janjetović, R. Slominski +5 more
2025Journal of Investigative Dermatology36 citations Open access
Semantic Scholar
Topically Applied Hsp90 Blocker 17AAG Inhibits Autoantibody-Mediated Blister-Inducing Cutaneous Inflammation.
S. Tukaj, K. Bieber, K. Kleszczyński, M. Witte +6 more
2017Journal of Investigative Dermatology35 citations Open access
Semantic Scholar
Mechanism of cytotoxic action of perfluorinated acids. III. Disturbance in Ca²+ homeostasis.
K. Kleszczyński, A. Składanowski
2011Toxicology and Applied Pharmacology33 citations
Semantic Scholar
Mitochondrial function is controlled by melatonin and its metabolites in vitro in human melanoma cells
Bernadetta Bilska, Fiona Schedel, A. Piotrowska, Joanna Stefan +7 more
2021Journal of Pineal Research32 citations Open access
Semantic Scholar
Unraveling Endothelial Cell Migration: Insights into Fundamental Forces, Inflammation, Biomaterial Applications, and Tissue Regeneration Strategies
D. Jerka, Klaudia Bonowicz, Klaudia Piekarska, Seyda Gokyer +8 more
2024ACS Applied Bio Materials31 citations Open access
Semantic Scholar
Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection
R. Reiter, Ramaswamy Sharma, F. Simko, A. Domínguez-Rodríguez +7 more
2022Cellular and Molecular Life Sciences30 citations Open access
Semantic Scholar
New effects of caffeine on corticotropin-releasing hormone (CRH)-induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the neurogenic non-HPA axis (substance P, p75NTR and TrkA) in ex vivo human male androgenetic scalp hair fo
T. Fischer, A. Bergmann, N. Kruse, K. Kleszczyński +3 more
2020British Journal of Dermatology29 citations Open access
Semantic Scholar
Development of a short-term human full-thickness skin organ culture model in vitro under serum-free conditions
K. Kleszczyński, T. Fischer
2012Archives of Dermatological Research25 citations
Semantic Scholar
Development of tannic acid-enriched materials modified by poly(ethylene glycol) for potential applications as wound dressing
B. Kaczmarek, O. Mazur, O. Miłek, M. Michalska-Sionkowska +2 more
2020Progress in Biomaterials24 citations Open access
Semantic Scholar
Autoimmunity to heat shock proteins and vitamin D status in patients with celiac disease without associated dermatitis herpetiformis.
S. Tukaj, A. Görög, K. Kleszczyński, D. Zillikens +2 more
2017Journal of Steroid Biochemistry and Molecular Biology22 citations
Semantic Scholar
Expression of antimicrobial peptide genes oscillates along day/night rhythm protecting mice skin from bacteria
Bernadetta Bilska, A. Zegar, A. Słominski, K. Kleszczyński +2 more
2020Experimental Dermatology21 citations Open access
Semantic Scholar
Novel Eco-Friendly Tannic Acid-Enriched Hydrogels-Preparation and Characterization for Biomedical Application
B. Kaczmarek, O. Miłek, M. Michalska-Sionkowska, L. Zasada +4 more
2020Materials21 citations Open access
Semantic Scholar
Evaluation of Polymeric Matrix Loaded with Melatonin for Wound Dressing
B. Kaczmarek-Szczepańska, J. Ostrowska, J. Kozłowska, Z. Szota +6 more
2021International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
Vitiligo auto‐immune response upon oxidative stress‐related mitochondrial DNA release opens up new therapeutic strategies
A. C. Sant'Anna-Silva, T. Botton, Andrea Rossi, J. Dobner +11 more
2024Clinical and Translational Medicine17 citations Open access
Semantic Scholar
Ultraviolet Radiation-Induced Mitochondrial Disturbances Are Attenuated by Metabolites of Melatonin in Human Epidermal Keratinocytes
Chantal E. Holtkamp, Dawid Warmus, Klaudia Bonowicz, M. Gagat +7 more
2023Metabolites17 citations Open access
Semantic Scholar
Normal and cancer cells response on the thin films based on chitosan and tannic acid.
B. Kaczmarek, O. Miłek, K. Nadolna, A. Owczarek +2 more
2020Toxicology in Vitro17 citations Open access
Semantic Scholar
Mechanism of Extracellular Vesicle Secretion Associated with TGF-β-Dependent Inflammatory Response in the Tumor Microenvironment
Klaudia Bonowicz, Klaudia Mikołajczyk, Inaz Faisal, Murtaz Qamar +4 more
2022International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Assessment of Melatonin-Cultured Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials for Wound Healing
B. Kaczmarek-Szczepańska, Judith M. Pin, L. Zasada, Mauritz M. Sonne +4 more
2022Antioxidants16 citations Open access
Semantic Scholar
The Characterization of Scaffolds Based on Dialdehyde Chitosan/Hyaluronic Acid
Sylwia Grabska-Zielińska, Adrianna Sosik, A. Malkowska, E. Olewnik-Kruszkowska +3 more
2021Materials13 citations Open access
Semantic Scholar
Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy
K. Adamiak, Vivian A. Gaida, J. Schäfer, Lina Bosse +6 more
2024International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
Role of Cyclins and Cytoskeletal Proteins in Endometriosis: Insights into Pathophysiology
Marcin Szymański, Klaudia Bonowicz, P. Antosik, D. Jerka +5 more
2024Cancers12 citations Open access
Semantic Scholar
Melatonin and TGF-β-Mediated Release of Extracellular Vesicles
Klaudia Piekarska, Klaudia Bonowicz, A. Grzanka, Ł. Jaworski +5 more
2023Metabolites12 citations Open access
Semantic Scholar
Scaffolds Loaded with Dialdehyde Chitosan and Collagen—Their Physico-Chemical Properties and Biological Assessment
Sylwia Grabska-Zielińska, Judith M. Pin, B. Kaczmarek-Szczepańska, E. Olewnik-Kruszkowska +4 more
2022Polymers12 citations Open access
Semantic Scholar
Differential and Overlapping Effects of Melatonin and Its Metabolites on Keratinocyte Function: Bioinformatics and Metabolic Analyses
Joanna Stefan, Tae-Kang Kim, Fiona Schedel, Z. Janjetović +8 more
2021Antioxidants12 citations Open access
Semantic Scholar

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