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M. Asselin · SciRah

Researcher profile · Semantic Scholar

M. Asselin

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M. Asselin — researcher profile on SciRah

h-index: 38
Works: 128
Citations: 5,969

Most-cited papers

Elevated striatal dopamine function linked to prodromal signs of schizophrenia.
O. Howes, A. Montgomery, M. Asselin, R. Murray +8 more
2009Archives of General Psychiatry767 citations
Semantic Scholar
Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation
Steve Poirier, G. Mayer, V. Poupon, P. McPherson +9 more
2009Journal of Biological Chemistry265 citations Open access
Semantic Scholar
Abnormal frontostriatal interactions in people with prodromal signs of psychosis: a multimodal imaging study.
P. Fusar-Poli, O. Howes, P. Allen, M. Broome +4 more
2010Archives of General Psychiatry244 citations
Semantic Scholar
Targeting Hypoxia to Improve Non–Small Cell Lung Cancer Outcome
A. Salem, M. Asselin, B. Reymen, A. Jackson +4 more
2018Journal of the National Cancer Institute230 citations Open access
Semantic Scholar
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Can Mediate Degradation of the Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1)
Maryssa Canuel, Xiaowei Sun, M. Asselin, E. Paramithiotis +2 more
2013PLoS ONE224 citations Open access
Semantic Scholar
Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis
P. Fusar-Poli, Od Howes, P. Allen, M. Broome +5 more
2011Molecular Psychiatry214 citations Open access
Semantic Scholar
A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo
N. Gupta, Niels Fisker, M. Asselin, M. Lindholm +5 more
2010PLoS ONE199 citations Open access
Semantic Scholar
Quantitative imaging biomarkers in the clinical development of targeted therapeutics: current and future perspectives.
James P. B. O'Connor, Alan Jackson, M. Asselin, David L. Buckley +2 more
2008The Lancet Oncology184 citations
Semantic Scholar
Quantifying heterogeneity in human tumours using MRI and PET.
M. Asselin, J. O'Connor, R. Boellaard, N. Thacker +1 more
2012European Journal of Cancer174 citations Open access
Semantic Scholar
PCSK9 impedes hepatitis C virus infection in vitro and modulates liver CD81 expression
P. Labonté, Syntia Begley, C. Guévin, M. Asselin +4 more
2009Hepatology161 citations Open access
Semantic Scholar
Pre-synaptic striatal dopaminergic function in people at high risk of psychosis
O. Howes, A. Montgomery, M. Asselin, R. Murray +2 more
2007The British journal of psychiatry. Supplement159 citations Open access
Semantic Scholar
P-glycoprotein Expression and Pharmacoresistant Epilepsy: Cause or Consequence?
P-glycoprotein Expression, M. Feldmann, M. Asselin, Joan Y. W. Liu +8 more
2014124 citations
Semantic Scholar
Bias in iterative reconstruction of low-statistics PET data: benefits of a resolution model
M. Walker, M. Asselin, P. Julyan, M. Feldmann +3 more
20092009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)110 citations
Semantic Scholar
Upregulation of opioid receptor binding following spontaneous epileptic seizures.
A. Hammers, M. Asselin, R. Hinz, I. Kitchen +3 more
2007Brain : a journal of neurology107 citations Open access
Semantic Scholar
The Regulated Cell Surface Zymogen Activation of the Proprotein Convertase PC5A Directs the Processing of Its Secretory Substrates*
G. Mayer, J. Hamelin, M. Asselin, A. Pasquato +4 more
2008Journal of Biological Chemistry93 citations Open access
Semantic Scholar
Measurement of Methylphenidate-Induced Change in Extrastriatal Dopamine Concentration using [11C]FLB 457 PET
A. Montgomery, M. Asselin, L. Farde, P. Grasby
2007Journal of Cerebral Blood Flow and Metabolism91 citations
Semantic Scholar
Evidence for endogenous opioid release in the amygdala during positive emotion
M. Koepp, A. Hammers, A. Lawrence, M. Asselin +2 more
2009NeuroImage79 citations
Semantic Scholar
Oxygen-enhanced MRI Is Feasible, Repeatable, and Detects Radiotherapy-induced Change in Hypoxia in Xenograft Models and in Patients with Non–small Cell Lung Cancer
A. Salem, R. Little, A. Latif, Adam K. Featherstone +16 more
2019Clinical Cancer Research75 citations Open access
Semantic Scholar
In vivo methods for imaging blood–brain barrier function and dysfunction
William Harris, M. Asselin, R. Hinz, L. Parkes +4 more
2022European Journal of Nuclear Medicine and Molecular Imaging73 citations Open access
Semantic Scholar
Effects of the Prosegment and pH on the Activity of PCSK9
S. Benjannet, Y. G. Luna Saavedra, J. Hamelin, M. Asselin +9 more
2010Journal of Biological Chemistry73 citations Open access
Semantic Scholar
The Proprotein Convertase SKI-1/S1P
A. Pasquato, Philomena Pullikotil, M. Asselin, M. Vacatello +6 more
2006Journal of Biological Chemistry71 citations Open access
Semantic Scholar
Quantification of PET Studies with the Very High-Affinity Dopamine D2/D3 Receptor Ligand [11C]FLB 457: Re-Evaluation of the Validity of using a Cerebellar Reference Region
M. Asselin, A. Montgomery, P. Grasby, S. Hume
2007Journal of Cerebral Blood Flow and Metabolism65 citations Open access
Semantic Scholar
Furin Is the Major Processing Enzyme of the Cardiac-specific Growth Factor Bone Morphogenetic Protein 10*
Delia Susan-Resiga, R. Essalmani, J. Hamelin, M. Asselin +8 more
2011Journal of Biological Chemistry64 citations Open access
Semantic Scholar
Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes*
R. Essalmani, Delia Susan-Resiga, A. Chamberland, M. Asselin +7 more
2013Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other*
C. Butkinaree, Maryssa Canuel, R. Essalmani, Steve Poirier +12 more
2015Journal of Biological Chemistry54 citations Open access
Semantic Scholar
Balancing bias, reliability, noise properties and the need for parametric maps in quantitative ligand PET: [11C]diprenorphine test-retest data
A. Hammers, M. Asselin, F. Turkheimer, R. Hinz +5 more
2007NeuroImage47 citations
Semantic Scholar
Early reduction in tumour [18F]fluorothymidine (FLT) uptake in patients with non-small cell lung cancer (NSCLC) treated with radiotherapy alone
I. Trigonis, P. Koh, B. Taylor, M. Tamal +9 more
2014European Journal of Nuclear Medicine and Molecular Imaging46 citations Open access
Semantic Scholar
In vivo P-glycoprotein function before and after epilepsy surgery
M. Bauer, R. Karch, M. Zeitlinger, Joan Y. W. Liu +9 more
2014Neurology45 citations Open access
Semantic Scholar
Investigation of motion induced errors in scatter correction for the HRRT brain scanner
J. Anton-Rodriguez, M. Sibomana, M. Walker, M. Huisman +4 more
2010IEEE Nuclear Science Symposuim & Medical Imaging Conference38 citations
Semantic Scholar
Proprotein Convertase PC7 Enhances the Activation of the EGF Receptor Pathway through Processing of the EGF Precursor*
Estelle Rousselet, S. Benjannet, E. Marcinkiewicz, M. Asselin +2 more
2011Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation*
Elodie Weider, Delia Susan-Resiga, R. Essalmani, J. Hamelin +7 more
2016Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Optimization of the Injected Activity in Dynamic 3D PET: A Generalized Approach Using Patient-Specific NECs as Demonstrated by a Series of 15O-H2O Scans
M. Walker, J. Matthews, M. Asselin, A. Saleem +5 more
2009Journal of Nuclear Medicine23 citations Open access
Semantic Scholar
The Validation Path of Hypoxia PET Imaging: Focus on Brain Tumours.
N. Quartuccio, M. Asselin
2017Current Medicinal Chemistry22 citations Open access
Semantic Scholar
The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation
Delia Susan-Resiga, E. Girard, Robert S. Kiss, R. Essalmani +9 more
2016Journal of Biological Chemistry21 citations Open access
Semantic Scholar
P‐glycoprotein overactivity in epileptogenic developmental lesions measured in vivo using (R)‐[11C]verapamil PET
Maria Ilyas-Feldmann, M. Asselin, Shaonan Wang, A. McMahon +6 more
2020Epilepsia19 citations Open access
Semantic Scholar
18F-FLT PET imaging of cellular proliferation in pancreatic cancer.
A. Lamarca, M. Asselin, P. Manoharan, M. McNamara +4 more
2016Critical reviews in oncology/hematology17 citations
Semantic Scholar
Cell Death, Inflammation, Tumor Burden, and Proliferation Blood Biomarkers Predict Lung Cancer Radiotherapy Response and Correlate With Tumor Volume and Proliferation Imaging
A. Salem, H. Mistry, A. Backen, C. Hodgson +11 more
2017Clinical Lung Cancer15 citations Open access
Semantic Scholar
Quantification of [11C]GB67 binding to cardiac α1-adrenoceptors with positron emission tomography: validation in pigs
So-Jin Park-Holohan, M. Asselin, D. Turton, Sharron L. Williams +3 more
2008European Journal of Nuclear Medicine and Molecular Imaging15 citations
Semantic Scholar
Optimization of methods for quantification of rCBF using high-resolution [15O]H2O PET images
M. Walker, M. Feldmann, J. Matthews, J. Anton-Rodriguez +3 more
2012Physics in Medicine and Biology14 citations Open access
Semantic Scholar
Comparison of HRRT and HR+ Scanners for Quantitative (R)-[11C]verapamil, [11C]raclopride and [11C]flumazenil Brain Studies
F. V. van Velden, S. Mansor, D. V. van Assema, B. N. van Berckel +7 more
2015Molecular Imaging and Biology13 citations Open access
Semantic Scholar
Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue
F. Lepelletier, M. Vandesquille, M. Asselin, C. Prenant +12 more
2020Theranostics12 citations Open access
Semantic Scholar
Thrombin activation of protein C requires prior processing by a liver proprotein convertase
R. Essalmani, Delia Susan-Resiga, Johann Guillemot, W. Kim +9 more
2017Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Repeatability of quantitative 18F-FLT uptake measurements in solid tumors: an individual patient data multi-center meta-analysis
G. Kramer, Yan Liu, A. D. de Langen, Elise P. Jansma +7 more
2018European Journal of Nuclear Medicine and Molecular Imaging11 citations Open access
Semantic Scholar
Deferoxamine stimulates LDLR expression and LDL uptake in HepG2 cells.
Johann Guillemot, M. Asselin, Delia Susan-Resiga, R. Essalmani +1 more
2016Molecular Nutrition & Food Research11 citations Open access
Semantic Scholar
Phase I evaluation of vascular disrupting agent OXi4503
D. Patterson, N. Charnley, A. Saleem, M. Stratford +6 more
200810 citations
Semantic Scholar
Phase I evaluation of OXi4503, a vascular disrupting agent, in patients with advanced solid tumours
D. Patterson, P. Ross, B. Koetz, A. Saleem +6 more
20078 citations
Semantic Scholar
Experimental validation of estimated spatially variant radioisotope-specific point spread functions using published positron range simulations and fluorine-18 measurements
J. Anton-Rodriguez, G. Krokos, F. Kotasidis, M. Asselin +4 more
2018Physics in Medicine and Biology5 citations Open access
Semantic Scholar
Development and validation of a variance model for dynamic PET: uses in fitting kinetic data and optimizing the injected activity
M. Walker, J. Matthews, M. Asselin, C. Watson +6 more
2010Physics in Medicine and Biology5 citations Open access
Semantic Scholar
WC4E THE PRE-SYNAPTIC DOPAMINERGIC SYSTEM BEFORE AND AFTER THE ONSET OF PSYCHOSIS: INITIAL RESULTS FROM AN ONGOING [18F]FLUORO-DOPA PET STUDY
O. Howes, A. Montgomery, M. Asselin, R. Murray +2 more
20065 citations
Semantic Scholar
The pre-synaptic dopaminergic system before and after the onset of psychosis: initial results
O. Howes, S. A. Montgomery, M. Asselin, Robin M. Murray +2 more
20065 citations
Semantic Scholar

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