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James M. Osborne · SciRah

Researcher profile · Semantic Scholar

James M. Osborne

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James M. Osborne — researcher profile on SciRah

h-index: 25
Works: 64
Citations: 2,745

Most-cited papers

Chaste: An Open Source C++ Library for Computational Physiology and Biology
Gary R. Mirams, Christopher J. Arthurs, M. Bernabeu, R. Bordas +13 more
2013PLoS Comput. Biol.452 citations Open access
Semantic Scholar
Chaste: A test-driven approach to software development for biological modelling
J. Pitt-Francis, P. Pathmanathan, M. Bernabeu, R. Bordas +15 more
2009Computer Physics Communications278 citations Open access
Semantic Scholar
Comparing individual-based approaches to modelling the self-organization of multicellular tissues
James M. Osborne, A. Fletcher, Joe M. Pitt-Francis, P. Maini +1 more
2016bioRxiv241 citations Open access
Semantic Scholar
Cooperation, competition and antibiotic resistance in bacterial colonies
Isabel Frost, William P. J. Smith, Sara Mitri, Á. S. Millán +5 more
2018The ISME Journal191 citations Open access
Semantic Scholar
Cell morphology drives spatial patterning in microbial communities
William P. J. Smith, Y. Davit, James M. Osborne, Wook Kim +2 more
2016Proceedings of the National Academy of Sciences of the United States of America165 citations Open access
Semantic Scholar
Implementing vertex dynamics models of cell populations in biology within a consistent computational framework.
A. Fletcher, James M. Osborne, P. Maini, D. Gavaghan
2013Progress in Biophysics and Molecular Biology161 citations Open access
Semantic Scholar
Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche
A. Langlands, A. Almet, P. Appleton, I. Newton +2 more
2016PLoS Biology99 citations Open access
Semantic Scholar
Chaste: using agile programming techniques to develop computational biology software
J. Pitt-Francis, M. Bernabeu, J. Cooper, A. Garny +6 more
2008Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences92 citations Open access
Semantic Scholar
Chaste: Cancer, Heart and Soft Tissue Environment
Fergus R. Cooper, Ruth Baker, M. Bernabeu, R. Bordas +25 more
2020Journal of Open Source Software89 citations Open access
Semantic Scholar
Reversible host cell remodeling underpins deformability changes in malaria parasite sexual blood stages
M. Dearnley, T. Chu, Yao Zhang, O. Looker +10 more
2016Proceedings of the National Academy of Sciences of the United States of America78 citations Open access
Semantic Scholar
Computational Models Reveal a Passive Mechanism for Cell Migration in the Crypt
S. Dunn, I. Näthke, James M. Osborne
2013PLoS ONE64 citations Open access
Semantic Scholar
A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness
T. J. Sego, Josua O. Aponte-Serrano, Juliano Ferrari Gianlupi, S. Heaps +7 more
2020bioRxiv63 citations Open access
Semantic Scholar
Ten Simple Rules for a Successful Cross-Disciplinary Collaboration
B. Knapp, R. Bardenet, M. Bernabeu, R. Bordas +16 more
2015PLoS Comput. Biol.62 citations Open access
Semantic Scholar
Seven challenges in the multiscale modeling of multicellular tissues
A. Fletcher, James M. Osborne
2020WIREs Mechanisms of Disease61 citations Open access
Semantic Scholar
The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt
S. Kay, H. Harrington, S. Shepherd, Keith Brennan +4 more
2016PLoS Comput. Biol.57 citations Open access
Semantic Scholar
Ten Simple Rules for Effective Computational Research
James M. Osborne, M. Bernabeu, M. Bruna, B. Calderhead +16 more
2014PLoS Comput. Biol.57 citations Open access
Semantic Scholar
A Two-Dimensional Model of the Colonic Crypt Accounting for the Role of the Basement Membrane and Pericryptal Fibroblast Sheath
S. Dunn, P. Appleton, S. Nelson, I. Näthke +2 more
2012PLoS Comput. Biol.52 citations Open access
Semantic Scholar
Hydrodynamic dispersion within porous biofilms.
Y. Davit, H. Byrne, James M. Osborne, Joe Pitt-Francis +2 more
2013Physical review. E, Statistical, nonlinear, and soft matter physics41 citations Open access
Semantic Scholar
Mechano-logical model of C. elegans germ line suggests feedback on the cell cycle
Kathryn Atwell, Z. Qin, D. Gavaghan, H. Kugler +2 more
2015Development38 citations Open access
Semantic Scholar
Evaluation of the Growth Environment of a Hydrostatic Force Bioreactor for Preconditioning of Tissue-Engineered Constructs
Y. Reinwald, K. H. Leonard, James R. Henstock, J. Whiteley +4 more
2014Tissue Engineering. Part C, Methods38 citations Open access
Semantic Scholar
Colorectal cancer through simulation and experiment.
S. K. Kershaw, H. Byrne, D. Gavaghan, James M. Osborne
2013IET Systems Biology34 citations Open access
Semantic Scholar
Push or Pull? Cell Proliferation and Migration During Wound Healing
Adriana Zanca, J. Flegg, James M. Osborne
2022Frontiers in Systems Biology30 citations Open access
Semantic Scholar
Interkinetic nuclear migration and basal tethering facilitates post-mitotic daughter separation in intestinal organoids
Thomas D. Carroll, A. Langlands, James M. Osborne, I. Newton +2 more
2017Journal of Cell Science27 citations Open access
Semantic Scholar
The Free Energy Landscape of Dimerization of a Membrane Protein, NanC
T. Dunton, Joseph E. Goose, D. Gavaghan, M. Sansom +1 more
2014PLoS Comput. Biol.26 citations Open access
Semantic Scholar
On-lattice agent-based simulation of populations of cells within the open-source Chaste framework
G. Figueredo, T. Joshi, James M. Osborne, H. Byrne +1 more
2013Interface Focus25 citations Open access
Semantic Scholar
Chaste: An Open Source C plus plus Library for Computational Physiology and Biology
Gary R. Mirams, Christopher J. Arthurs, M. Bernabeu, R. Bordas +13 more
201322 citations
Semantic Scholar
A parallel implementation of an off-lattice individual-based model of multicellular populations
D. G. Harvey, A. Fletcher, James M. Osborne, J. Pitt-Francis
2015Computer Physics Communications20 citations
Semantic Scholar
A rigid body framework for multicellular modeling
P. J. Brown, J. E. F. Green, B. J. Binder, James M. Osborne
2021Nature Computational Science19 citations
Semantic Scholar
A Multicellular Model of Intestinal Crypt Buckling and Fission
A. Almet, B. Hughes, K. Landman, I. Näthke +1 more
2017Bulletin of Mathematical Biology18 citations Open access
Semantic Scholar
CoGNaC: A Chaste Plugin for the Multiscale Simulation of Gene Regulatory Networks Driving the Spatial Dynamics of Tissues and Cancer
S. Rubinacci, A. Graudenzi, G. Caravagna, G. Mauri +3 more
2015Cancer Informatics16 citations Open access
Semantic Scholar
Mathematical models of developmental vascular remodelling: A review
Jessica R. Crawshaw, J. Flegg, M. Bernabeu, James M. Osborne
2023PLoS Comput. Biol.15 citations Open access
Semantic Scholar
Multiscale Model of Colorectal Cancer Using the Cellular Potts Framework
James M. Osborne
2015Cancer Informatics12 citations Open access
Semantic Scholar
Validity of the Cauchy-Born rule applied to discrete cellular-scale models of biological tissues.
Y. Davit, James M. Osborne, Helen M. Byrne, D. Gavaghan +1 more
2013Physical review. E, Statistical, nonlinear, and soft matter physics12 citations Open access
Semantic Scholar
Traffic Patterns of the Migrating Endothelium: How Force Transmission Regulates Vascular Malformation and Functional Shunting During Angiogenic Remodelling
Lowell T. Edgar, H. Park, Jessica R. Crawshaw, James M. Osborne +2 more
2022Frontiers in Cell and Developmental Biology10 citations Open access
Semantic Scholar
Connecting Models to Data in Multiscale Multicellular Tissue Simulations
J. Cooper, James M. Osborne
2013International Conference on Conceptual Structures9 citations Open access
Semantic Scholar
A numerical method for the multiphase viscous flow equations
James M. Osborne, J. Whiteley
20109 citations
Semantic Scholar
Modelling Cellular Interactions and Dynamics During Kidney Morphogenesis
Blake J. Cook, Alexander N. Combes, M. Little, James M. Osborne
2021Bulletin of Mathematical Biology8 citations
Semantic Scholar
Maintaining the proliferative cell niche in multicellular models of epithelia.
Claire Miller, E. Crampin, James M. Osborne
2018Journal of Theoretical Biology8 citations Open access
Semantic Scholar
A multiscale model of viral infection in epithelial tissues
T. J. Sego, Josua O. Aponte-Serrano, Julia Ferrari, James M. Osborne +3 more
8 citations
Semantic Scholar
Multiscale modelling of desquamation in the interfollicular epidermis
Claire Miller, E. Crampin, James M. Osborne
2021PLoS Comput. Biol.7 citations Open access
Semantic Scholar
Free and Interfacial Boundaries in Individual-Based Models of Multicellular Biological systems
Domenic P. J. Germano, Adriana Zanca, S. Johnston, J. Flegg +1 more
2023bioRxiv6 citations Open access
Semantic Scholar
A mathematical model of cell fate selection on a dynamic tissue.
Domenic P. J. Germano, James M. Osborne
2020Journal of Theoretical Biology6 citations Open access
Semantic Scholar
Stochastic clonal expansion of "superstars" enhances the reserve capacity of enteric nervous system precursor cells.
Dongcheng Zhang, James M. Osborne, K. D. Abu-Bonsrah, Bevan L. Cheeseman +3 more
2018Developmental Biology5 citations Open access
Semantic Scholar
How quickly does a wound heal? Bayesian calibration of a mathematical model of venous leg ulcer healing.
Adriana Zanca, James M. Osborne, S. Zaloumis, C. Weller +1 more
2022Mathematical Medicine and Biology-a Journal of The Ima4 citations
Semantic Scholar
A simple history dependent remeshing technique to increase finite element model stability in elastic surface deformations
Jessica R. Crawshaw, J. Flegg, James M. Osborne
2020Journal of Computational and Applied Mathematics4 citations Open access
Semantic Scholar
Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt
L. Romijn, A. Almet, Chin-Wee Tan, James M. Osborne
2019BMC Bioinformatics4 citations Open access
Semantic Scholar
Modelling realistic 3D deformations of simple epithelia in dynamic homeostasis.
D. Germano, S. Johnston, E. Crampin, James M. Osborne
2022Mathematical Biosciences3 citations Open access
Semantic Scholar
On an infrastructure to support sharing and aggregating pre- and post-publication systems biology research data
Mark Slaymaker, James M. Osborne, A. Simpson, D. Gavaghan
2012Journal of Systems and Synthetic Biology2 citations Open access
Semantic Scholar
Addressing Interdisciplinary Difficulties in Developmental Biology/Mathematical Collaborations: A Neural Crest Example.
D. Newgreen, K. Landman, James M. Osborne
2019Methods in molecular biology1 citations
Semantic Scholar
Skip segment Hirschsprung disease: modelling the trans-mesenteric origin of the enteric nervous system in the human colon
D. Newgreen, James M. Osborne, Dongcheng Zhang
2019bioRxiv1 citations Open access
Semantic Scholar

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D. Gavaghan×17
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J. Pitt-Francis×11
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A. Fletcher×10
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M. Bernabeu×9
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Gary R. Mirams×5

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