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R. Simpson · SciRah

Researcher profile · Semantic Scholar

R. Simpson

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R. Simpson — researcher profile on SciRah

h-index: 32
Works: 141
Citations: 6,195

Most-cited papers

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation.
A. Mckie, P. Marciani, A. Rolfs, K. Brennan +9 more
2000Molecules and Cells1,460 citations Open access
Semantic Scholar
An Iron-Regulated Ferric Reductase Associated with the Absorption of Dietary Iron
A. Mckie, D. Barrow, G. Latunde-Dada, A. Rolfs +12 more
2001Science1,117 citations
Semantic Scholar
Identification of an intestinal heme transporter.
M. Shayeghi, G. Latunde-Dada, J. Oakhill, A. Laftah +11 more
2005Cell783 citations
Semantic Scholar
Physiology and molecular biology of dietary iron absorption.
S. Miret, R. Simpson, A. Mckie
2003Annual review of nutrition310 citations
Semantic Scholar
Effect of hepcidin on intestinal iron absorption in mice.
A. Laftah, B. Ramesh, R. Simpson, Nita Solanky +4 more
2004Blood238 citations
Semantic Scholar
COX-1 and 2, intestinal integrity, and pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in mice.
G. Sigthorsson, R. Simpson, M. Walley, A. Anthony +7 more
2002Gastroenterology194 citations Open access
Semantic Scholar
Recent advances in mammalian haem transport.
G. Latunde-Dada, R. Simpson, A. Mckie
2006TIBS -Trends in Biochemical Sciences. Regular ed116 citations
Semantic Scholar
Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism.
T. Lambe, R. Simpson, S. Dawson, Tiphaine Bouriez‐Jones +12 more
2009Blood106 citations Open access
Semantic Scholar
Tumour necrosis factor α causes hypoferraemia and reduced intestinal iron absorption in mice
A. Laftah, N. Sharma, M. Brookes, A. Mckie +3 more
200694 citations Open access
Semantic Scholar
Rate of 59Fe Uptake into Brain and Cerebrospinal Fluid and the Influence Thereon of Antibodies Against the Transferrin Receptor
F. Ueda, K. Raja, R. Simpson, I. Trowbridge +1 more
1993Journal of Neurochemistry92 citations
Semantic Scholar
Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1)
A. Laftah, G. Latunde-Dada, S. Fakih, R. Hider +2 more
2008British Journal of Nutrition88 citations Open access
Semantic Scholar
A nano-disperse ferritin-core mimetic that efficiently corrects anemia without luminal iron redox activity
J. Powell, S. Bruggraber, N. Faria, Lynsey K. Poots +6 more
2014Nanomedicine: Nanotechnology, Biology and Medicine75 citations Open access
Semantic Scholar
Duodenal cytochrome B expression stimulates iron uptake by human intestinal epithelial cells.
G. Latunde-Dada, R. Simpson, A. Mckie
2008Journal of NutriLife70 citations Open access
Semantic Scholar
Tumour necrosis factor alpha causes hypoferraemia and reduced intestinal iron absorption in mice.
A. Laftah, N. Sharma, M. Brookes, A. Mckie +3 more
2006Biochemical Journal67 citations
Semantic Scholar
Expression of iron absorption genes in mouse large intestine
K. Takeuchi, I. Bjarnason, A. Laftah, G. Latunde-Dada +2 more
2005Scandinavian Journal of Gastroenterology67 citations
Semantic Scholar
Tissue-specific changes in iron metabolism genes in mice following phenylhydrazine-induced haemolysis.
G. Latunde-Dada, Chris D. Vulpe, Gregory J. Anderson, R. Simpson +1 more
2004Biochimica et Biophysica Acta59 citations Open access
Semantic Scholar
Animal models with enhanced erythropoiesis and iron absorption.
G. Latunde-Dada, A. Mckie, R. Simpson
2006Biochimica et Biophysica Acta55 citations Open access
Semantic Scholar
Duodenal reductase activity and spleen iron stores are reduced and erythropoiesis is abnormal in Dcytb knockout mice exposed to hypoxic conditions.
Jee-Young Choi, P. Masaratana, G. Latunde-Dada, M. Arno +2 more
2012Journal of NutriLife54 citations Open access
Semantic Scholar
Regulation of intestinal iron absorption: the mucosa takes control?
R. Simpson, A. Mckie
2009Cell Metabolism50 citations Open access
Semantic Scholar
Synthesis and characterization of mixed phase anatase TiO2 and sodium-doped TiO2(B) thin films by low pressure chemical vapour deposition (LPCVD)
Y. Chimupala, G. Hyett, R. Simpson, R. Mitchell +3 more
201447 citations
Semantic Scholar
Role of bile in pathogenesis of indomethacin-induced enteropathy
M. Jacob, R. Foster, G. Sigthorsson, R. Simpson +1 more
2007Archives of Toxicology47 citations
Semantic Scholar
Quantitation of hepcidin in human urine by liquid chromatography-mass spectrometry.
S. Bansal, J. Halket, A. Bomford, R. Simpson +3 more
2009Analytical Biochemistry44 citations
Semantic Scholar
Quantification of hepcidin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
S. Bansal, J. Halket, Jane Fusova, A. Bomford +4 more
2009Rapid Communications in Mass Spectrometry43 citations
Semantic Scholar
Intestinal iron absorption studies in mouse models of iron‐overload
K. Raja, R. Simpson, T. Peters
1994British Journal of Haematology41 citations
Semantic Scholar
Characterization of the transition-metal-binding properties of hepcidin.
C. Tselepis, S. Ford, A. Mckie, W. Vogel +5 more
2010Biochemical Journal39 citations Open access
Semantic Scholar
Iron speciation at physiological pH in media containing ascorbate and oxygen
C. Dorey, C. Cooper, D. P. E. Dickson, J. Gibson +2 more
1993British Journal of Nutrition38 citations Open access
Semantic Scholar
A Nanoparticulate Ferritin-Core Mimetic Is Well Taken Up by HuTu 80 Duodenal Cells and Its Absorption in Mice Is Regulated by Body Iron
G. Latunde-Dada, Dora I. A. Pereira, B. Tempest, H. Ilyas +4 more
2014Journal of NutriLife37 citations Open access
Semantic Scholar
BMPER Protein Is a Negative Regulator of Hepcidin and Is Up-regulated in Hypotransferrinemic Mice*
N. Patel, P. Masaratana, J. Díaz-Castro, G. Latunde-Dada +11 more
2011Journal of Biological Chemistry36 citations Open access
Semantic Scholar
Iron absorption: biochemical and molecular insights into the importance of iron species for intestinal uptake.
P. Cremonesi, Álvaro Acebrón, K. Raja, R. Simpson
2002Acta Pharmacologica et Toxicologica36 citations Open access
Semantic Scholar
Iron and oxygen sensing: a tale of 2 interacting elements?
R. Simpson, A. Mckie
2015Metallomics32 citations
Semantic Scholar
Enantiomers of flurbiprofen can distinguish key pathophysiological steps of NSAID enteropathy in the rat
T. Mahmud, S. Somasundaram, G. Sigthorsson, R. Simpson +10 more
1998Gut31 citations Open access
Semantic Scholar
The transcription factor ATOH8 is regulated by erythropoietic activity and regulates HAMP transcription and cellular pSMAD1,5,8 levels
N. Patel, Joe Varghese, P. Masaratana, G. Latunde-Dada +3 more
2013British Journal of Haematology29 citations Open access
Semantic Scholar
Duodenal ascorbate and ferric reductase in human iron deficiency.
B. Atanasova, Andy C. Y. Li, I. Bjarnason, K. Tzatchev +1 more
2005American Journal of Clinical Nutrition25 citations Open access
Semantic Scholar
Biochemical and Molecular Actions of Nutrients Duodenal Ascorbate Levels Are Changed in Mice with Altered Iron Metabolism
B. Atanasova, I. Mudway, A. Laftah, G. Latunde-Dada +4 more
200425 citations
Semantic Scholar
Regulation of iron metabolism in Hamp−/− mice in response to iron-deficient diet
P. Masaratana, N. Patel, G. Latunde-Dada, S. Vaulont +2 more
2013European Journal of Nutrition19 citations
Semantic Scholar
Role of COX-2 in nonsteroidal anti-inflammatory drug enteropathy in rodents
C. Hotz-behofsits, R. Simpson, M. Walley, I. Bjarnason
2010Scandinavian Journal of Gastroenterology19 citations
Semantic Scholar
Duodenal cytochrome b (Cybrd 1) and HIF-2α expression during acute hypoxic exposure in mice
G. Latunde-Dada, Lan Xiang, R. Simpson, A. Mckie
2011European Journal of Nutrition16 citations
Semantic Scholar
Iron absorption in hepcidin1 knockout mice.
P. Masaratana, A. Laftah, G. Latunde-Dada, S. Vaulont +2 more
2011British Journal of Nutrition14 citations Open access
Semantic Scholar
Iron and cadmium uptake by duodenum of hypotransferrinaemic mice
K. Raja, S. E. Jafri, T. Peters, R. Simpson
2006Biometals14 citations
Semantic Scholar
Uptake of 26-Al and 67-Ga into brain and other tissues of normal and hypotransferrinaemic mice
A. Radunović, F. Ueda, K. Raja, R. Simpson +5 more
1997Biometals14 citations
Semantic Scholar
Mucosal surface ferricyanide reductase activity in mouse duodenum
D. Pountney, K. Raja, Matthew J. Bottwood, J. Wrigglesworth +1 more
2004Biometals12 citations
Semantic Scholar
Hypoxic response of iron absorption is not affected by the Hfe gene knock‐out in mice
A. Laftah, R. Simpson, N. Beaumont, S. Bahram +2 more
2003British Journal of Haematology12 citations Open access
Semantic Scholar
Duodenal mucosal reductase in wild-type and Hfe knockout mice on iron adequate, iron deficient, and iron rich feeding
R. Simpson, E. Debnam, N. Beaumont, S. Bahram +2 more
2003Gut12 citations Open access
Semantic Scholar
The effects of inhibition of haem biosynthesis by griseofulvin on intestinal iron absorption.
A. Laftah, K. Raja, N. Beaumont, R. Simpson +4 more
2004Basic & Clinical Pharmacology & Toxicology11 citations
Semantic Scholar
Iron metabolism in hepcidin1 knockout mice in response to phenylhydrazine-induced hemolysis.
P. Masaratana, G. Latunde-Dada, N. Patel, R. Simpson +2 more
2012Blood Cells, Molecules & Diseases10 citations
Semantic Scholar
Duodenal nonheme iron content correlates with iron stores in mice, but the relationship is altered by Hfe gene knock-out.
R. Simpson, E. Debnam, A. Laftah, Nita Solanky +4 more
2003Blood10 citations
Semantic Scholar
Non steroidal anti-inflammatory drugs, cyclooxygenase selectivity and gastrointestinal toxicity.
M. Jacob, R. Simpson, Ingvar Bjarnason
1998Italian journal of gastroenterology and hepatology10 citations
Semantic Scholar
Effect of Tin‐mesoporphyrin, an inhibitor of haem catabolism, on intestinal iron absorption
A. Laftah, K. Raja, R. Simpson, Timothy J. Peters
2003British Journal of Haematology9 citations
Semantic Scholar
Expression of ABCG2 (BCRP) in mouse models with enhanced erythropoiesis
G. Latunde-Dada, A. Laftah, P. Masaratana, A. Mckie +1 more
2014Frontiers in Pharmacology8 citations Open access
Semantic Scholar
Effects of indomethacin on energy metabolism in rat jejunal tissue in vivo.
M. Jacob, I. Bjarnason, R. Simpson
2002Clinical science8 citations
Semantic Scholar

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A. Mckie×25
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A. Mckie — researcher profile on SciRah
G. Latunde-Dada×20
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G. Latunde-Dada — researcher profile on SciRah
A. Laftah×13
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A. Laftah — researcher profile on SciRah
K. Raja×10
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K. Raja — researcher profile on SciRah

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T. Peters — researcher profile on SciRah

P. Masaratana×7

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P. Masaratana — researcher profile on SciRah

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M. Jacob — researcher profile on SciRah

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A. Bomford — researcher profile on SciRah

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R. Hider — researcher profile on SciRah

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I. Bjarnason — researcher profile on SciRah