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S. Vaulont · SciRah

Researcher profile · Semantic Scholar

S. Vaulont

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S. Vaulont — researcher profile on SciRah

h-index: 64
Works: 168
Citations: 17K

Most-cited papers

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).
C. Peyssonnaux, A. Zinkernagel, R. Schuepbach, Erinn B. Rankin +4 more
2007Journal of Clinical Investigation662 citations Open access
Semantic Scholar
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.
M. Claret, Mark A. Smith, R. Batterham, C. Selman +13 more
2007Journal of Clinical Investigation544 citations Open access
Semantic Scholar
HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.
Maria Mastrogiannaki, Pavle Matak, Brian Keith, M. Simon +2 more
2009Journal of Clinical Investigation472 citations Open access
Semantic Scholar
Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.
L. Kautz, D. Meynard, A. Monnier, V. Darnaud +7 more
2008Blood459 citations Open access
Semantic Scholar
Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis.
Jeanne-Claire Lesbordes-Brion, L. Viatte, M. Bennoun, D. Lou +5 more
2006Blood247 citations Open access
Semantic Scholar
Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin.
F. Andreelli, M. Foretz, C. Knauf, Patrice D Cani +9 more
2006Endocrinology236 citations Open access
Semantic Scholar
The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels
Wing-Hang Tong, C. Sourbier, Gennady Kovtunovych, S. Y. Jeong +14 more
2011Cancer Cell212 citations Open access
Semantic Scholar
Hepcidin targets ferroportin for degradation in hepatocytes
G. Ramey, J. Deschemin, B. Durel, F. Canonne-Hergaux +2 more
2010Haematologica199 citations Open access
Semantic Scholar
Role of AMPKalpha2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle.
S. Jørgensen, J. T. Treebak, B. Viollet, P. Schjerling +3 more
2007American Journal of Physiology. Endocrinology and Metabolism186 citations
Semantic Scholar
Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis
Maria Mastrogiannaki, Pavle Matak, J. Mathieu, S. Delga +3 more
2012Haematologica161 citations Open access
Semantic Scholar
Hepcidin, the iron watcher.
L. Viatte, S. Vaulont
2009Biochimie133 citations
Semantic Scholar
Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes
G. Ramey, J. Deschemin, S. Vaulont
2009Haematologica124 citations Open access
Semantic Scholar
Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing
N. Bessman, J. Mathieu, Cyril Renassia, Lei Zhou +17 more
2020Science123 citations Open access
Semantic Scholar
hepcidin-deficient mice Deregulation of proteins involved in iron metabolism in
François Canonne-Hergaux, S. Vaulont, L. Viatte, Jeanne-Claire Lesbordes-Brion +3 more
2010113 citations
Semantic Scholar
Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice.
L. Viatte, G. Nicolas, D. Lou, M. Bennoun +7 more
2006Blood99 citations
Semantic Scholar
Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice.
Majda Hadziahmetovic, Ying Song, P. Ponnuru, Jared Iacovelli +6 more
2011Investigative Ophthalmology and Visual Science98 citations Open access
Semantic Scholar
Inflammation and its impact on anaemia in chronic kidney disease: from haemoglobin variability to hyporesponsiveness
Á. D. de Francisco, P. Stenvinkel, S. Vaulont
2009NDT plus98 citations Open access
Semantic Scholar
Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia.
K. Michels, Zhimin Zhang, Alexandra M. Bettina, R. Cagnina +6 more
2017JCI Insight94 citations Open access
Semantic Scholar
The microbiota shifts the iron sensing of intestinal cells
J. Deschemin, Marie‐Louise Noordine, A. Rémot, A. Willemetz +7 more
2016The FASEB Journal91 citations
Semantic Scholar
Role of Hepcidin in the Setting of Hypoferremia during Acute Inflammation
J. Deschemin, S. Vaulont
2013PLoS ONE89 citations Open access
Semantic Scholar
Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection
Peggy Schwarz, J. Kübler, P. Strnad, K. Müller +7 more
2011Gut86 citations
Semantic Scholar
Targeted disruption of hepcidin in the liver recapitulates the hemochromatotic phenotype.
S. Zumerle, J. Mathieu, S. Delga, M. Heinis +3 more
2014Blood84 citations Open access
Semantic Scholar
Dual cardiac contractile effects of the alpha2-AMPK deletion in low-flow ischemia and reperfusion.
K. Carvajal, Elham Zarrinpashneh, O. Szárszoi, F. Joubert +9 more
2007American Journal of Physiology. Heart and Circulatory Physiology77 citations Open access
Semantic Scholar
Iron Regulator Hepcidin Impairs Macrophage-Dependent Cardiac Repair After Injury
Ivana Zlatanova, Cristina Pinto, P. Bonnin, J. Mathieu +7 more
2019Circulation71 citations Open access
Semantic Scholar
Hepcidin regulates intrarenal iron handling at the distal nephron.
Boualem Moulouel, Dounia Houamel, C. Delaby, Dimitri Tchernitchko +7 more
2013Kidney International68 citations Open access
Semantic Scholar
Interleukin-6 contributes to hepcidin mRNA increase in response to exercise.
S. Banzet, H. Sanchez, R. Chapot, X. Bigard +2 more
2012Cytokine67 citations
Semantic Scholar
Copper Deficiency Leads to Anemia, Duodenal Hypoxia, Upregulation of HIF-2α and Altered Expression of Iron Absorption Genes in Mice
Pavle Matak, S. Zumerle, Maria Mastrogiannaki, S. El Balkhi +7 more
2013PLoS ONE65 citations Open access
Semantic Scholar
Hepcidin knockout mice fed with iron-rich diet develop chronic liver injury and liver fibrosis due to lysosomal iron overload.
M. Lunova, C. Goehring, D. Kuscuoglu, K. Mueller +8 more
2014Journal of Hepatology64 citations
Semantic Scholar
Deletion of HIF-2α in the enterocytes decreases the severity of tissue iron loading in hepcidin knockout mice.
Maria Mastrogiannaki, Pavle Matak, S. Delga, J. Deschemin +2 more
2012Blood54 citations
Semantic Scholar
Oncostatin M is a potent inducer of hepcidin, the iron regulatory hormone
B. Chung, F. Verdier, Pavle Matak, J. Deschemin +2 more
2010The FASEB Journal54 citations
Semantic Scholar
Hepcidin as a Major Component of Renal Antibacterial Defenses against Uropathogenic Escherichia coli.
Dounia Houamel, Nicolas Ducrot, T. Lefèbvre, R. Daher +14 more
2016Journal of the American Society of Nephrology52 citations Open access
Semantic Scholar
Pro-hepcidin is unable to degrade the iron exporter ferroportin unless maturated by a furin-dependent process.
B. Gagliardo, Nicole J. Kubat, A. Faye, M. Jaouen +5 more
2009Journal of Hepatology52 citations
Semantic Scholar
AMP-Activated Protein Kinase α2 Deficiency Affects Cardiac Cardiolipin Homeostasis and Mitochondrial Function
Yoni Athéa, B. Viollet, P. Mateo, D. Rousseau +8 more
2007Diabetes48 citations Open access
Semantic Scholar
Hepcidin-dependent and hepcidin-independent regulation of erythropoiesis in a mouse model of anemia of chronic inflammation
Jacqueline M. Langdon, Saiah C. Yates, Laurette K. Femnou, Bryan J. McCranor +6 more
2014American journal of hematology/oncology45 citations Open access
Semantic Scholar
Hepcidin knockout mice spontaneously develop chronic pancreatitis owing to cytoplasmic iron overload in acinar cells
M. Lunova, Peggy Schwarz, R. Nuraldeen, K. Levada +10 more
2017Journal of Pathology41 citations Open access
Semantic Scholar
Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in Macrophages during Salmonella Infection
A. Willemetz, S. Beatty, E. Richer, Aude Rubio +6 more
2017Frontiers in Immunology41 citations Open access
Semantic Scholar
Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload
M. Spasić, R. Sparla, Katarzyna Mleczko-Sanecka, M. C. Migas +5 more
2012Biochimica et Biophysica Acta41 citations Open access
Semantic Scholar
Low transferrin levels predict heightened inflammation in patients with COVID-19: New insights
C. Claise, J. Saleh, Marwa Rezek, S. Vaulont +2 more
2021International Journal of Infectious Diseases37 citations Open access
Semantic Scholar
Production of biologically active forms of recombinant hepcidin, the iron‐regulatory hormone
B. Gagliardo, A. Faye, M. Jaouen, J. Deschemin +3 more
2008The FEBS Journal37 citations Open access
Semantic Scholar
Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.
A. Lenoir, J. Deschemin, L. Kautz, A. Ramsay +4 more
2011Blood35 citations Open access
Semantic Scholar
Inactive matriptase‐2 mutants found in IRIDA patients still repress hepcidin in a transfection assay despite having lost their serine protease activity
F. Guillem, C. Kannengiesser, C. Oudin, A. Lenoir +9 more
2012Human Mutation34 citations Open access
Semantic Scholar
Maintenance of red blood cell integrity by AMP‐activated protein kinase α1 catalytic subunit
M. Foretz, S. Guihard, J. Leclerc, V. Fauveau +6 more
2010FEBS Letters34 citations Open access
Semantic Scholar
Neutrophils from hereditary hemochromatosis patients are protected from iron excess and are primed.
Cyril Renassia, Sabine Louis, S. Cuvellier, N. Boussetta +10 more
2020Blood Advances32 citations Open access
Semantic Scholar
Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis.
A. Willemetz, A. Lenoir, J. Deschemin, C. López-Otín +3 more
2014Blood31 citations Open access
Semantic Scholar
Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with age
Bryan J. McCranor, J. Langdon, Olivier D. Prince, Laurette K. Femnou +10 more
2013Haematologica31 citations Open access
Semantic Scholar
Pulmonary Iron Homeostasis in Hepcidin Knockout Mice
J. Deschemin, J. Mathieu, S. Zumerle, C. Peyssonnaux +1 more
2017Frontiers in Physiology30 citations Open access
Semantic Scholar
Iron overload in Hepc1 −/− mice is not impairing glucose homeostasis
G. Ramey, A. Faye, B. Durel, B. Viollet +1 more
2007FEBS Letters29 citations
Semantic Scholar
Hepcidin is essential for alveolar macrophage function and is disrupted by smoke in a murine COPD model
E. Perez, J. Baker, S. di Giandomenico, P. Kermani +9 more
2020Journal of Immunology23 citations Open access
Semantic Scholar
USF-1 Is Critical for Maintaining Genome Integrity in Response to UV-Induced DNA Photolesions
Yorann Baron, Sébastien Corre, Nicolas Mouchet, S. Vaulont +2 more
2012PLoS Genetics23 citations Open access
Semantic Scholar
Increased intracellular iron in mouse primary hepatocytes in vitro causes activation of the Akt pathway but decreases its response to insulin
Joe Varghese, J. V. James, S. Vaulont, A. Mckie +1 more
2018Biochimica et Biophysica Acta - General Subjects22 citations Open access
Semantic Scholar

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J. Deschemin×14
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J. Deschemin — researcher profile on SciRah
C. Peyssonnaux×12
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F. Canonne-Hergaux×7
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B. Viollet — researcher profile on SciRah

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J. Mathieu — researcher profile on SciRah

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Maria Mastrogiannaki — researcher profile on SciRah

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S. Delga — researcher profile on SciRah

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S. Zumerle — researcher profile on SciRah