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M. Winterhalter · SciRah

Researcher profile · Semantic Scholar

M. Winterhalter

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M. Winterhalter — researcher profile on SciRah

h-index: 61
Works: 287
Citations: 14K

Most-cited papers

Towards the sustainable discovery and development of new antibiotics
M. Miethke, M. Pieroni, T. Weber, M. Brönstrup +50 more
2021Nature Reviews Chemistry944 citations Open access
Semantic Scholar
Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria
Julia Vergalli, I. Bodrenko, Muriel Masi, L. Moynié +7 more
2019Nature Reviews Microbiology353 citations Open access
Semantic Scholar
How to Enter a Bacterium: Bacterial Porins and the Permeation of Antibiotics.
J. D. Prajapati, U. Kleinekathöfer, M. Winterhalter
2021Chemical Reviews235 citations Open access
Semantic Scholar
Structural basis for nutrient acquisition by dominant members of the human gut microbiota
A. J. Glenwright, K. Pothula, S. P. Bhamidimarri, D. Chorev +8 more
2017Nature220 citations Open access
Semantic Scholar
Large-Conductance Transmembrane Porin Made from DNA Origami
K. Göpfrich, Chen-Yu Li, M. Ricci, S. P. Bhamidimarri +6 more
2016ACS Nano165 citations Open access
Semantic Scholar
Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins.
S. Acosta-Gutiérrez, L. Ferrara, M. Pathania, Muriel Masi +10 more
2018ACS Infectious Diseases144 citations Open access
Semantic Scholar
Ion Channels Made from a Single Membrane-Spanning DNA Duplex
K. Göpfrich, Chen-Yu Li, Iwona Mames, S. P. Bhamidimarri +8 more
2016Nano letters (Print)120 citations Open access
Semantic Scholar
The 2018 correlative microscopy techniques roadmap
T. Ando, S. P. Bhamidimarri, Niklas Brending, H. Colin-York +32 more
2018Journal of Physics D: Applied Physics114 citations Open access
Semantic Scholar
Bacterial Outer Membrane Porins as Electrostatic Nanosieves: Exploring Transport Rules of Small Polar Molecules.
Harsha Bajaj, Silvia Acosta Gutiérrez, I. Bodrenko, G. Malloci +3 more
2017ACS Nano90 citations Open access
Semantic Scholar
Breaching the Barrier: Quantifying Antibiotic Permeability across Gram-negative Bacterial Membranes.
Jehangir Cama, A. Henney, M. Winterhalter
2019Journal of Molecular Biology76 citations Open access
Semantic Scholar
Identification of Single Amino Acid Chiral and Positional Isomers Using an Electrostatically Asymmetric Nanopore
Jia-Jun Wang, J. D. Prajapati, Fan Gao, Yilun Ying +3 more
2022Journal of the American Chemical Society69 citations Open access
Semantic Scholar
Outer Membrane Porins.
Muriel Masi, M. Winterhalter, J. Pagés
2019Sub-cellular biochemistry63 citations
Semantic Scholar
The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux
Julia Vergalli, Alessio Atzori, Jelena Pajović, Estelle Dumont +7 more
2020Communications Biology59 citations Open access
Semantic Scholar
General Method to Determine the Flux of Charged Molecules through Nanopores Applied to β-Lactamase Inhibitors and OmpF.
Ishan Ghai, A. Pira, M. A. Scorciapino, I. Bodrenko +4 more
2017Journal of Physical Chemistry Letters58 citations Open access
Semantic Scholar
Role of Electroosmosis in the Permeation of Neutral Molecules: CymA and Cyclodextrin as an Example.
S. P. Bhamidimarri, J. D. Prajapati, B. van den Berg, M. Winterhalter +1 more
2016Biophysical Journal56 citations Open access
Semantic Scholar
Kanamycin uptake into Escherichia coli is facilitated by OmpF and OmpC porin channels located in the outer membrane.
J. Bafna, Eulàlia Sans-Serramitjana, S. Acosta-Gutiérrez, I. Bodrenko +5 more
2020ACS Infectious Diseases55 citations Open access
Semantic Scholar
A Multidisciplinary Approach toward Identification of Antibiotic Scaffolds for Acinetobacter baumannii.
S. P. Bhamidimarri, M. Zahn, J. D. Prajapati, C. Schleberger +7 more
2019Structure48 citations Open access
Semantic Scholar
The structural basis for low conductance in the membrane protein VDAC upon β–NADH binding and voltage gating
Raphael Böhm, G. Amodeo, Sruthi Murlidaran, S. Chavali +4 more
2019Structure40 citations Open access
Semantic Scholar
Metallacarborane Cluster Anions of the Cobalt Bisdicarbollide-Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides
Yao Chen, Andrea Barba‐Bon, B. Grüner, M. Winterhalter +8 more
2023Journal of the American Chemical Society38 citations Open access
Semantic Scholar
Mechanisms of intrinsic resistance and acquired susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients to temocillin, a revived antibiotic
Hussein Chalhoub, Daniel Pletzer, H. Weingart, Y. Braun +9 more
2017Scientific Reports38 citations Open access
Semantic Scholar
Electrophysiological Characterization of Transport Across Outer‐Membrane Channels from Gram‐Negative Bacteria in Presence of Lipopolysaccharides
Jia-Jun Wang, Rémi Terrasse, J. Bafna, L. Benier +1 more
2020Angewandte Chemie37 citations Open access
Semantic Scholar
Getting Drugs through Small Pores: Exploiting the Porins Pathway in Pseudomonas aeruginosa.
Susruta Samanta, I. Bodrenko, S. Acosta-Gutiérrez, Tommaso D’Agostino +8 more
2018ACS Infectious Diseases37 citations Open access
Semantic Scholar
Characterization of Ciprofloxacin Permeation Pathways across the Porin OmpC Using Metadynamics and a String Method.
J. D. Prajapati, Carlos José Fernández Solano, M. Winterhalter, U. Kleinekathöfer
2017Journal of Chemical Theory and Computation37 citations Open access
Semantic Scholar
Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane
Muriel Masi, Julia Vergalli, Ishan Ghai, Andrea Barba‐Bon +5 more
2022Communications Biology35 citations Open access
Semantic Scholar
Ampicillin permeation across OmpF, the major outer-membrane channel in Escherichia coli
Ishan Ghai, Harsha Bajaj, Jayesh Arun Bafna, Hussein Ali El Damrany Hussein +2 more
2018Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade
G. Tetreau, A. Banneville, E. Andreeva, A. Brewster +34 more
2020Nature Communications33 citations Open access
Semantic Scholar
Engineering Enhanced Pore Sizes Using FhuA Δ1-160 from E. coli Outer Membrane as Template.
Zhanzhi Liu, Ishan Ghai, M. Winterhalter, U. Schwaneberg
2017ACS Sensors33 citations
Semantic Scholar
α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease.
Carlos Moreno-Cinos, Elisa Sassetti, Irene G. Salado, G. Witt +11 more
2019Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Probing transport of charged β-lactamase inhibitors through OmpC, a membrane channel from E. coli.
Ishan Ghai, M. Winterhalter, R. Wagner
2017Biochemical and Biophysical Research Communications - BBRC32 citations
Semantic Scholar
Small-Molecule Permeation across Membrane Channels: Chemical Modification to Quantify Transport across OmpF.
Jia-Jun Wang, J. Bafna, S. P. Bhamidimarri, M. Winterhalter
2018Angewandte Chemie31 citations Open access
Semantic Scholar
The Beauty of Asymmetric Membranes: Reconstitution of the Outer Membrane of Gram-Negative Bacteria
Laura Paulowski, Annemarie Donoghue, C. Nehls, Sabrina Groth +5 more
2020Frontiers in Cell and Developmental Biology30 citations Open access
Semantic Scholar
Protein A Functionalized Polyelectrolyte Microcapsules as a Universal Platform for Enhanced Targeting of Cell Surface Receptors.
T. A. Kolesnikova, Gayane Kiragosyan, Trang H. N. Le, S. Springer +1 more
2017ACS Applied Materials and Interfaces30 citations
Semantic Scholar
Fosfomycin Permeation through the Outer Membrane Porin OmpF.
V. Golla, Eulàlia Sans-Serramitjana, K. Pothula, L. Benier +3 more
2019Biophysical Journal27 citations Open access
Semantic Scholar
Enrofloxacin Permeation Pathways across the Porin OmpC.
J. D. Prajapati, C. J. Solano, M. Winterhalter, U. Kleinekathöfer
2018Journal of Physical Chemistry B24 citations
Semantic Scholar
How beta lactam antibiotics enter bacteria : a dialogue with the porins
C. James, Kozhinjampara R. Mahendran, Alexander Molitor, J. Bolla +3 more
201724 citations
Semantic Scholar
The cryo-EM structure of the S-layer deinoxanthin-binding complex of Deinococcus radiodurans informs properties of its environmental interactions
Domenica Farci, Patrycja Haniewicz, D. de Sanctis, L. Iesu +3 more
2022Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Structural insights into the main S-layer unit of Deinococcus radiodurans reveal a massive protein complex with porin-like features
Domenica Farci, M. A. Aksoyoglu, Stefano Francesco Farci, J. Bafna +6 more
2020Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Unusual Constriction Zones in the Major Porins OmpU and OmpT from Vibrio cholerae.
M. Pathania, S. Acosta-Gutiérrez, S. P. Bhamidimarri, A. Baslé +3 more
2018Structure22 citations Open access
Semantic Scholar
Sensing Single Molecule Penetration into Nanopores: Pushing the Time Resolution to the Diffusion Limit.
I. Bodrenko, Jiajun Wang, Samuele Salis, M. Winterhalter +1 more
2017ACS Sensors21 citations
Semantic Scholar
Structural analysis of the architecture and in situ localization of the main S-layer complex in Deinococcus radiodurans.
Domenica Farci, Sami Kereïche, Sushil Pangeni, Patrycja Haniewicz +4 more
2021Structure19 citations Open access
Semantic Scholar
Computational Modeling of Ion Transport in Bulk and through a Nanopore Using the Drude Polarizable Force Field
J. D. Prajapati, C. Mele, M. A. Aksoyoglu, M. Winterhalter +1 more
2020Journal of Chemical Information and Modeling18 citations
Semantic Scholar
Understanding Carbapenem Translocation through OccD3 (OpdP) of Pseudomonas aeruginosa.
G. Soundararajan, S. P. Bhamidimarri, M. Winterhalter
2017ACS Chemical Biology18 citations
Semantic Scholar
Antibiotic uptake through porins located in the outer membrane of Gram-negative bacteria
M. Winterhalter
2020Expert Opinion on Drug Delivery17 citations
Semantic Scholar
Conformational Dynamics of Loop L3 in OmpF: Implications toward Antibiotic Translocation and Voltage Gating
A. Acharya, Ishan Ghai, Claudio Piselli, J. D. Prajapati +3 more
2022Journal of Chemical Information and Modeling16 citations
Semantic Scholar
Electroosmosis Dominates Electrophoresis of Antibiotic Transport Across the Outer Membrane Porin F.
J. Bafna, Sushil Pangeni, M. Winterhalter, M. A. Aksoyoglu
2020Biophysical Journal16 citations Open access
Semantic Scholar
Dynamic interaction of fluoroquinolones with magnesium ions monitored using bacterial outer membrane nanopores
Jia-Jun Wang, J. D. Prajapati, U. Kleinekathöfer, M. Winterhalter
2020Chemical Science15 citations Open access
Semantic Scholar
Single Residue Acts as Gate in OccK Channels.
K. Pothula, N. Dhanasekar, Usha Lamichhane, F. Younas +4 more
2017Journal of Physical Chemistry B15 citations
Semantic Scholar
Biophysical characterization of E. coli TolC interaction with the known blocker hexaamminecobalt.
A. Gilardi, S. P. Bhamidimarri, M. Brönstrup, U. Bilitewski +6 more
2017Biochimica et Biophysica Acta - General Subjects15 citations
Semantic Scholar
Changes in Salt Concentration Modify the Translocation of Neutral Molecules through a ΔCymA Nanopore in a Non-monotonic Manner.
J. D. Prajapati, Sushil Pangeni, M. A. Aksoyoglu, M. Winterhalter +1 more
2022ACS Nano14 citations
Semantic Scholar
Probing transport of fosfomycin through substrate specific OprO and OprP from Pseudomonas aeruginosa.
F. Citak, Ishan Ghai, Frank Rosenkötter, L. Benier +2 more
2018Biochemical and Biophysical Research Communications - BBRC14 citations
Semantic Scholar

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