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M. Shackleton · SciRah

Researcher profile · Semantic Scholar

M. Shackleton

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M. Shackleton — researcher profile on SciRah

h-index: 38
Works: 148
Citations: 16K

Most-cited papers

Whole–genome characterization of chemoresistant ovarian cancer
A. Patch, E. Christie, D. Etemadmoghadam, D. Garsed +77 more
2015Nature1,537 citations
Semantic Scholar
Whole-genome landscapes of major melanoma subtypes
N. Hayward, J. Wilmott, N. Waddell, P. Johansson +45 more
2017Nature1,328 citations Open access
Semantic Scholar
MDM4 is a key therapeutic target in cutaneous melanoma
Agnieszka Gembarska, F. Luciani, C. Fedele, Elisabeth A. Russell +18 more
2012Nature Medicine314 citations Open access
Semantic Scholar
UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas.
Stephen Q. Wong, Kelly Waldeck, Ismael A. Vergara, Jan Schröder +26 more
2015Cancer Research294 citations Open access
Semantic Scholar
Integrative pathway enrichment analysis of multivariate omics data
M. Paczkowska, J. Barenboim, N. Sintupisut, Natalie S. Fox +129 more
2020Nature Communications212 citations Open access
Semantic Scholar
Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth.
M. Dewaele, Tommaso Tabaglio, K. Willekens, M. Bezzi +23 more
2016Journal of Clinical Investigation160 citations Open access
Semantic Scholar
The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma
R. Ramsdale, R. Jorissen, F. Z. Li, Sheren J. Al-Obaidi +14 more
2015Science Signaling137 citations Open access
Semantic Scholar
Human melanoma metastasis in NSG mice correlates with clinical outcome in patients
E. Quintana, E. Piskounova, M. Shackleton, Daniel N. Weinberg +4 more
2012Science Translational Medicine116 citations Open access
Semantic Scholar
Circulating Tumor DNA Analysis and Functional Imaging Provide Complementary Approaches for Comprehensive Disease Monitoring in Metastatic Melanoma.
Stephen Q. Wong, J. Raleigh, J. Callahan, Ismael A. Vergara +26 more
2017JCO Precision Oncology108 citations
Semantic Scholar
Socrates: identification of genomic rearrangements in tumour genomes by re-aligning soft clipped reads
Jan Schröder, A. Hsu, Samantha E. Boyle, G. Macintyre +5 more
2014Bioinform.86 citations Open access
Semantic Scholar
Long-term outcome in BRAFV600E melanoma patients treated with vemurafenib: Patterns of disease progression and clinical management of limited progression
I. Puzanov, R. Amaravadi, G. McArthur, K. Flaherty +9 more
2015European Journal of Cancer79 citations Open access
Semantic Scholar
The Hippo pathway oncoprotein YAP promotes melanoma cell invasion and spontaneous metastasis
Xiao-Meng Zhang, Lie Yang, Pacman Szeto, G. K. Abali +10 more
2020Oncogene75 citations Open access
Semantic Scholar
A community-based model of rapid autopsy in end-stage cancer patients
K. Alsop, H. Thorne, S. Sandhu, A. Hamilton +58 more
2016Nature Biotechnology71 citations
Semantic Scholar
Rheumatic immune-related adverse events secondary to anti-programmed death-1 antibodies and preliminary analysis on the impact of corticosteroids on anti-tumour response: A case series.
E. Mitchell, Peter K. H. Lau, C. Khoo, D. Liew +23 more
2018European Journal of Cancer67 citations
Semantic Scholar
Physiological Levels of Pik3ca H1047R Mutation in the Mouse Mammary Gland Results in Ductal Hyperplasia and Formation of ERα-Positive Tumors
A. Tikoo, V. Roh, K. Montgomery, Ivan. Ivetac +6 more
2012PLoS ONE66 citations Open access
Semantic Scholar
The use of ipilimumab in patients with rheumatoid arthritis and metastatic melanoma.
B. Lee, A. Wong, D. Kee, P. Neeson +3 more
2016Annals of Oncology61 citations Open access
Semantic Scholar
Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma
U. Eskiocak, V. Ramesh, Jennifer G. Gill, Zhi-Yu Zhao +9 more
2016Nature Communications60 citations Open access
Semantic Scholar
Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling
Ismael A. Vergara, Christopher P. Mintoff, S. Sandhu, Lachlan Mcintosh +37 more
2021Nature Communications59 citations Open access
Semantic Scholar
Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis
P. Bhave, L. Pallan, G. Long, A. Menzies +27 more
2020British Journal of Cancer58 citations Open access
Semantic Scholar
Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome
Lih Y. Tan, Christopher P. Mintoff, M. Johan, Brenton W Ebert +11 more
2016OncoTarget50 citations Open access
Semantic Scholar
A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis
Lisa M. Ebert, Lih Y. Tan, M. Johan, Kay Khine Myo Min +16 more
2016Angiogenesis44 citations Open access
Semantic Scholar
Feasibility and Acceptability of Fear-Less: A Stepped-Care Program to Manage Fear of Cancer Recurrence in People with Metastatic Melanoma
F. Lynch, L. Katona, M. Jefford, Allan Ben Smith +15 more
2020Journal of Clinical Medicine39 citations Open access
Semantic Scholar
Bevacizumab as a steroid‐sparing agent during immunotherapy for melanoma brain metastases: A case series
P. Banks, A. Lasocki, Peter K. H. Lau, S. Sandhu +2 more
2019Health Science Reports39 citations Open access
Semantic Scholar
Incidence, features and management of radionecrosis in melanoma patients treated with cerebral radiotherapy and anti-PD-1 antibodies
I. D. Da Silva, I. Glitza, L. Haydu, Romany A. N. Johnpulle +21 more
2019Pigment Cell & Melanoma Research34 citations Open access
Semantic Scholar
Cancer Diagnoses Following Abnormal Noninvasive Prenatal Testing: A Case Series, Literature Review, and Proposed Management Model.
Eryn Dow, A. Freimund, Kortnye Smith, R. Hicks +10 more
2021JCO Precision Oncology32 citations
Semantic Scholar
Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP
P. J. Paul, Dinesh Raghu, Ai-Leen Chan, Twishi Gulati +13 more
2016Oncogene32 citations
Semantic Scholar
Somatic Hypermutation of the YAP Oncogene in a Human Cutaneous Melanoma
Xiao-Meng Zhang, Jian-Zhong Tang, Ismael A. Vergara, Youfang Zhang +14 more
2019Molecular Cancer Research31 citations
Semantic Scholar
CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity.
Samantha E. Boyle, C. Fedele, Vincent D. A. Corbin, Elisha Wybacz +14 more
2016Cancer Research28 citations Open access
Semantic Scholar
UHRF1/UBE2L6/UBR4-mediated ubiquitination regulates EZH2 abundance and thereby melanocytic differentiation phenotypes in melanoma
Gamze Kuser-Abali, Youfang Zhang, Pacman Szeto, Peinan Zhao +11 more
2023Oncogene24 citations Open access
Semantic Scholar
Implementation of patient-reported outcome measures and patient-reported experience measures in melanoma clinical quality registries: a systematic review
Zachary Blood, A. Tran, Lauren Caleo, R. Saw +6 more
2021BMJ Open24 citations Open access
Semantic Scholar
Impact of Radiotherapy on the Efficacy and Toxicity of anti-PD-1 Inhibitors in Metastatic NSCLC.
E. Samuel, Gabrielle Lie, A. Balasubramanian, A. Hiong +10 more
2020Clinical Lung Cancer23 citations
Semantic Scholar
Corrigendum: Whole–genome characterization of chemoresistant ovarian cancer
A. Patch, E. Christie, D. Etemadmoghadam, D. Garsed +78 more
2015Nature22 citations Open access
Semantic Scholar
Post‐operative survival following metastasectomy for patients receiving BRAF inhibitor therapy is associated with duration of pre‐operative treatment and elective indication
Mike He, J. Lovell, Bee-Ling Ng, J. Spillane +4 more
2015Journal of Surgical Oncology22 citations
Semantic Scholar
Preclinical Models Provide Scientific Justification and Translational Relevance for Moving Novel Therapeutics into Clinical Trials for Pediatric Cancer.
Benjamin Gibert, P. Mehlen, D. Langenau, A. Sweet-Cordero +107 more
2015Cancer Research16 citations Open access
Semantic Scholar
Stereotactic radiotherapy combined with immunotherapy against metastatic melanoma: Long term results of a phase I clinical trial.
Gishan Ratnayake, S. Reinwald, M. Shackleton, M. Moore +8 more
2020International Journal of Radiation Oncology, Biology, Physics15 citations
Semantic Scholar
Immune checkpoint inhibitors and the risk of major atherosclerotic cardiovascular events in patients with high-risk or advanced melanoma: a retrospective cohort study
Charlie Wang, S. Zoungas, Mabel K Yan, R. Wolfe +7 more
2022Cardio-Oncology14 citations Open access
Semantic Scholar
Current management of advanced melanoma: a transformed landscape
D. Gyorki, J. Spillane, D. Speakman, M. Shackleton +1 more
2014ANZ journal of surgery14 citations Open access
Semantic Scholar
Phase I/II trial of concurrent extracranial palliative radiation therapy with Dabrafenib and Trametinib in metastatic BRAF V600E/K mutation-positive cutaneous Melanoma
Wen Wang, J. Smith, M. Carlino, B. Burmeister +11 more
2021Clinical and Translational Radiation Oncology13 citations Open access
Semantic Scholar
An update on adjuvant systemic therapies in melanoma
E. Samuel, M. Moore, M. Voskoboynik, M. Shackleton +1 more
2019Melanoma Management13 citations Open access
Semantic Scholar
Evaluation of Crizotinib Treatment in a Patient With Unresectable GOPC-ROS1 Fusion Agminated Spitz Nevi.
S. Robertson, L. Orme, R. Teixeira, Maryam Shamassi +16 more
2021JAMA dermatology12 citations Open access
Semantic Scholar
A peptide-signal amplification strategy for the detection and validation of neoepitope presentation on cancer biopsies
Sri H. Ramarathinam, P. Faridi, Angela Peng, Pacman Szeto +4 more
2020bioRxiv12 citations Open access
Semantic Scholar
Tumour procurement, DNA extraction, coverage analysis and optimisation of mutation-detection algorithms for human melanoma genomes
J. Wilmott, M. Field, P. Johansson, H. Kakavand +14 more
2015Pathology (Sydney)11 citations
Semantic Scholar
Reduced melanoma referrals during COVID-19 lockdown.
W. Berry, K. Tan, A. Haydon, M. Shackleton +1 more
2021Australian Journal of General Practice10 citations Open access
Semantic Scholar
Calcium-Dependent Enhancement by Extracellular Acidity of the Cytotoxicity of Mitochondrial Inhibitors against Melanoma
F. Noguchi, S. Inui, C. Fedele, M. Shackleton +1 more
2017Molecular Cancer Therapeutics7 citations
Semantic Scholar
Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24 + CD29/CD49fhi in mice
G. Dall, J. Vieusseux, Yashar Seyed‐Razavi, Nathan J. Godde +7 more
2020Breast Cancer Research and Treatment6 citations
Semantic Scholar
Case report: acute tumour lysis syndrome following encorafenib and binimetinib for v600E metastatic melanoma with large intra-abdominal mass.
Yoni Byron, L. Nott, M. Shackleton
2020Melanoma research6 citations
Semantic Scholar
Erratum: Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma
U. Eskiocak, V. Ramesh, Jennifer G. Gill, Zhi-Yu Zhao +9 more
2016Nature Communications6 citations Open access
Semantic Scholar
Surveillance imaging with FDG-PET in the follow-up of melanoma patients at high risk of relapse.
J. Lewin, Alexandra Sanelli, I. Walpole, D. Kee +11 more
20156 citations
Semantic Scholar
Incidence, features and management of radionecrosis (RN) in melanoma patients (pts) treated with cerebral radiotherapy (RT) and anti-PD-1 antibodies (PD1).
I. D. Da Silva, Romany A. N. Johnpulle, P. Banks, G. Grass +16 more
20175 citations
Semantic Scholar
CHARLI: A phase Ib/II trial of ipilimumab-nivolumab-denosumab or nivolumab-denosumab in patients with unresectable stage III and IV melanoma.
Peter K. H. Lau, S. Harris, M. Eastgate, D. Kee +16 more
2023Journal of Clinical Oncology4 citations Open access
Semantic Scholar

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