J. Rotman

Most-cited papers

1. PD-L1 and PD-L2 Expression in Cervical Cancer: Regulation and Biomarker Potential

   J. Rotman, Leontine A. S. den Otter, M. Bleeker, S. Samuels +7 more

   2020Frontiers in Immunology98 citations Open access

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2. Unlocking the therapeutic potential of primary tumor-draining lymph nodes

   J. Rotman, Bas D. Koster, E. Jordanova, A. Heeren +1 more

   2019Cancer Immunology and Immunotherapy78 citations Open access

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3. Efficacy of PD-1 blockade in cervical cancer is related to a CD8+FoxP3+CD25+ T-cell subset with operational effector functions despite high immune checkpoint levels

   A. Heeren, J. Rotman, A. Stam, N. Pocorni +8 more

   2019Journal of Immunotherapy for Cancer62 citations Open access

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4. ‘DURVIT’: a phase-I trial of single low-dose durvalumab (Medi4736) IntraTumourally injected in cervical cancer: safety, toxicity and effect on the primary tumour- and lymph node microenvironment

   J. Rotman, C. Mom, E. Jordanova, T. D. de Gruijl +1 more

   2018BMC Cancer31 citations Open access

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5. Immune landscape in vulvar cancer-draining lymph nodes indicates distinct immune escape mechanisms in support of metastatic spread and growth

   A. Heeren, J. Rotman, S. Samuels, H. Zijlmans +6 more

   2021Journal for ImmunoTherapy of Cancer26 citations Open access

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6. Delta-Like Ligand–Notch1 Signaling Is Selectively Modulated by HPV16 E6 to Promote Squamous Cell Proliferation and Correlates with Cervical Cancer Prognosis

   M. Khelil, H. Griffin, M. Bleeker, R. Steenbergen +10 more

   2021Cancer Research24 citations

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7. Immunotherapeutic Approaches for the Treatment of HPV-Associated (Pre-)Cancer of the Cervix, Vulva and Penis

   Tynisha S. Rafael, J. Rotman, O. Brouwer, H. G. van der Poel +4 more

   2022Journal of Clinical Medicine22 citations Open access

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8. Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8+ T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma

   J. Rotman, A. Heeren, A. Gassama, S. Lougheed +8 more

   2020Clinical Cancer Research22 citations Open access

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9. HPV-16 E6/E7 DNA tattoo vaccination using genetically optimized vaccines elicit clinical and immunological responses in patients with usual vulvar intraepithelial neoplasia (uVIN): a phase I/II clinical trial

   Noor A. M. Bakker, J. Rotman, M. van Beurden, Henry J. Maa Zijlmans +12 more

   2021Journal for ImmunoTherapy of Cancer15 citations Open access

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10. MICROENVIRONMENT IN TUMOR-DRAINING LYMPH NODES FROM PATIENTS WITH HPV-RELATED VULVAR CANCER

    H. J. M. A. A. Zijlmans, M. Heeren, S. Samuels, J. Rotman +6 more

    20171 citations

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11. Phase-1 trial of neoadjuvant durvalumab immunotherapy (DURVIT) delivered peritumorally in early-stage cervical cancer: safety and immune efficacy data

    M. Strikwerda, J. Rotman, E. Jordanova, J. Bakker +9 more

    2026International Journal of Gynecological Cancer0 citations

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