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N. Darzentas · SciRah

Researcher profile · Semantic Scholar

N. Darzentas

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N. Darzentas — researcher profile on SciRah

h-index: 35
Works: 165
Citations: 5,778

Most-cited papers

Standardized next-generation sequencing of immunoglobulin and T-cell receptor gene recombinations for MRD marker identification in acute lymphoblastic leukaemia; a EuroClonality-NGS validation study
M. Brüggemann, M. Kotrová, H. Knecht, J. Bartram +33 more
2019Leukemia233 citations Open access
Semantic Scholar
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations
R. Rosenquist, P. Ghia, A. Hadzidimitriou, L. Sutton +9 more
2017Leukemia141 citations Open access
Semantic Scholar
Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study.
P. Baliakas, A. Hadzidimitriou, L. Sutton, E. Minga +44 more
2014The Lancet Haematology118 citations
Semantic Scholar
Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technical feasibility study by EuroClonality-NGS
B. Scheijen, R. Meijers, J. Rijntjes, M. Y. van der Klift +16 more
2019Leukemia106 citations Open access
Semantic Scholar
ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data
V. Bystrý, T. Reigl, A. Krejčí, M. Demko +16 more
2016Bioinform.90 citations Open access
Semantic Scholar
Quality control and quantification in IG/TR next-generation sequencing marker identification: protocols and bioinformatic functionalities by EuroClonality-NGS
H. Knecht, T. Reigl, M. Kotrová, F. Appelt +30 more
2019Leukemia77 citations Open access
Semantic Scholar
ARResT/AssignSubsets: a novel application for robust subclassification of chronic lymphocytic leukemia based on B cell receptor IG stereotypy
V. Bystrý, A. Agathangelidis, V. Bikos, L. Sutton +4 more
2015Bioinform.59 citations Open access
Semantic Scholar
High-Throughput Immunogenetics for Clinical and Research Applications in Immunohematology: Potential and Challenges
A. Langerak, M. Brüggemann, F. Davi, N. Darzentas +11 more
2017Journal of Immunology54 citations Open access
Semantic Scholar
Validation of the EuroClonality-NGS DNA capture panel as an integrated genomic tool for lymphoproliferative disorders.
J. Stewart, J. Gazdová, N. Darzentas, D. Wren +30 more
2021Blood Advances47 citations
Semantic Scholar
Prognostic value of low-level MRD in adult acute lymphoblastic leukemia detected by low- and high-throughput methods
M. Kotrová, Johannes Koopmann, H. Trautmann, N. Alakel +10 more
2022Blood Advances39 citations Open access
Semantic Scholar
NGS better discriminates true MRD positivity for the risk stratification of childhood ALL treated on an MRD-based protocol
M. Svatoň, Aneta Skotnicova, L. Reznickova, Andrea Rennerova +10 more
2022Blood37 citations Open access
Semantic Scholar
Gene capture by transposable elements leads to epigenetic conflict in maize.
A. Muyle, Danelle K. Seymour, N. Darzentas, Elias Primetis +2 more
2020Molecular Plant33 citations Open access
Semantic Scholar
Next generation sequencing-based clonality assessment of immunoglobulin gene rearrangements: a multicenter validation study by EuroClonality-NGS.
M. van den Brand, J. Rijntjes, Markus Möbs, J. Steinhilber +16 more
2021Journal of Molecular Diagnostics30 citations Open access
Semantic Scholar
Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes
A. Xochelli, P. Baliakas, Ioannis Kavakiotis, A. Agathangelidis +58 more
2017Clinical Cancer Research30 citations Open access
Semantic Scholar
IgG-Switched CLL Has a Distinct Immunogenetic Signature from the Common MD Variant: Ontogenetic Implications
A. Vardi, A. Agathangelidis, L. Sutton, M. Chatzouli +9 more
2013Clinical Cancer Research30 citations Open access
Semantic Scholar
The presence of CLL-associated stereotypic B cell receptors in the normal BCR repertoire from healthy individuals increases with age
Alice F. Muggen, Madelon M. E. de Jong, I. Wolvers-Tettero, M. Kallemeijn +13 more
2019Immunity & Ageing28 citations Open access
Semantic Scholar
Comprehensive genetic analysis by targeted sequencing identifies risk factors and predicts patient outcome in Mantle Cell Lymphoma: results from the EU-MCL network trials
M. Khouja, Linmiao Jiang, Karol Pal, P. J. Stewart +11 more
2024Leukemia25 citations Open access
Semantic Scholar
A role for palindromic structures in the cis-region of maize Sirevirus LTRs in transposable element evolution and host epigenetic response
Alexandros Bousios, C. M. Diez, S. Takuno, V. Bystrý +2 more
2016Genome Research25 citations Open access
Semantic Scholar
An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2*04 Receptors
V. Bikos, M. Karypidou, E. Stalika, P. Baliakas +25 more
2015Clinical Cancer Research24 citations Open access
Semantic Scholar
Topology and expressed repertoire of the Felis catus T cell receptor loci
Araya Radtanakatikanon, S. Keller, N. Darzentas, P. Moore +4 more
2020BMC Genomics23 citations Open access
Semantic Scholar
Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia
A. Xochelli, A. Agathangelidis, Ioannis Kavakiotis, E. Minga +24 more
2014Immunogenetics23 citations
Semantic Scholar
No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy
P. Baliakas, M. Mattsson, A. Hadzidimitriou, E. Minga +36 more
2017Haematologica22 citations Open access
Semantic Scholar
Lack of common TCRA and TCRB clonotypes in CD8+/TCRαβ+ T-cell large granular lymphocyte leukemia: a review on the role of antigenic selection in the immunopathogenesis of CD8+ T-LGL
Y. Sandberg, Mj Kallemeijn, W. Dik, D. Tielemans +7 more
2014Blood Cancer Journal22 citations Open access
Semantic Scholar
A Simple RNA Target Capture NGS Strategy for Fusion Genes Assessment in the Diagnostics of Pediatric B-cell Acute Lymphoblastic Leukemia
A. Grioni, G. Fazio, S. Rigamonti, V. Bystrý +10 more
2019HemaSphere20 citations Open access
Semantic Scholar
The significance of stereotyped B-cell receptors in chronic lymphocytic leukemia.
N. Darzentas, K. Stamatopoulos
2013Hematology/Oncology Clinics of North America18 citations
Semantic Scholar
Sirevirus LTR retrotransposons: phylogenetic misconceptions in the plant world
Alexandros Bousios, N. Darzentas
2013Mobile DNA18 citations Open access
Semantic Scholar
High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans
A. Roy, V. Bystrý, Georg Bohn, K. Goudevenou +9 more
2017Clinical Immunology17 citations Open access
Semantic Scholar
Automation of amplicon-based library preparation for next generation sequencing by centrifugal microfluidics.
J. F. Hess, M. Kotrová, Silvia Calabrese, N. Darzentas +4 more
2020Analytical Chemistry15 citations
Semantic Scholar
Characterization of the canine immunoglobulin heavy chain repertoire by next generation sequencing.
Mei-Hua Hwang, N. Darzentas, D. Bienzle, P. Moore +2 more
2018Veterinary Immunology and Immunopathology15 citations
Semantic Scholar
Immune Gene Rearrangements: Unique Signatures for Tracing Physiological Lymphocytes and Leukemic Cells
M. Kotrová, N. Darzentas, C. Pott, C. Baldus +1 more
2021Genes14 citations Open access
Semantic Scholar
Composite lymphoma of concurrent T zone lymphoma and large cell B cell lymphoma in a dog
Arata Matsuyama, D. Bienzle, Danielle M Richardson, N. Deravi +3 more
2019BMC Veterinary Research14 citations Open access
Semantic Scholar
LYMPHOID NEOPLASIA Not all IGHV 3-21 chronic lymphocytic leukemias are equal : prognostic considerations
P. Baliakas, A. Agathangelidis, A. Hadzidimitriou, L. Sutton +44 more
201514 citations
Semantic Scholar
EuroClonality-NGS recommendations for evaluation of B cell clonality analysis by next-generation sequencing - a structured approach with the DEPART algorithm.
M. van den Brand, Markus Möbs, F. Otto, L. Kroeze +13 more
2023Journal of Molecular Diagnostics13 citations Open access
Semantic Scholar
Considerations and complications of mapping small RNA high-throughput data to transposable elements
Alexandros Bousios, B. Gaut, N. Darzentas
2017Mobile DNA11 citations Open access
Semantic Scholar
Clonotype definitions for immunogenetic studies: proposals from the EuroClonality NGS Working Group
E. Sofou, E. Vlachonikola, L. Zaragoza-Infante, M. Brüggemann +8 more
2023Leukemia10 citations Open access
Semantic Scholar
GLASS: assisted and standardized assessment of gene variations from Sanger sequence trace data
K. Pal, V. Bystrý, T. Reigl, M. Demko +9 more
2016bioRxiv10 citations Open access
Semantic Scholar
Somatic TP53 mutations are preleukemic events in acute lymphoblastic leukemia
G. Chitadze, A. Stengel, C. John-Klaua, Julien Bruckmüller +18 more
2022Blood9 citations Open access
Semantic Scholar
Genetic drivers in the natural history of chronic lymphocytic leukemia development as early as 16 years before diagnosis
P. M. Kolijn, Florentin Späth, M. Khouja, P. Hengeveld +7 more
2023Blood8 citations Open access
Semantic Scholar
cfDNA-Based NGS IG Analysis in Lymphoma.
C. Pott, M. Kotrová, N. Darzentas, M. Brüggemann +1 more
2022Methods in molecular biology8 citations Open access
Semantic Scholar
Insights into IGH clonal evolution in BCP-ALL: frequency, mechanisms, associations, and diagnostic implications
Franziska Darzentas, M. Szczepanowski, M. Kotrová, A. Hartmann +8 more
2023Frontiers in Immunology7 citations Open access
Semantic Scholar
Multiple immunoglobulin kappa rearrangements within a single clone unraveled by NGS-based clonality assessment.
A. M. Leenders, L. Kroeze, J. Rijntjes, J. Luijks +5 more
2021Journal of Molecular Diagnostics7 citations Open access
Semantic Scholar
A review of canine B cell clonality assays and primer set optimization using large-scale repertoire data.
Mei-Hua Hwang, N. Darzentas, D. Bienzle, P. Moore +3 more
2019Veterinary Immunology and Immunopathology7 citations Open access
Semantic Scholar
IGH Rearrangement Evolution in Adult KMT2A-rearranged B-cell Precursor ALL: Implications for Cell-of-origin and MRD Monitoring
Franziska Darzentas, M. Szczepanowski, M. Kotrová, Miriam Kelm +9 more
2022HemaSphere6 citations Open access
Semantic Scholar
A novel next-generation sequencing capture-based strategy to report somatic hypermutation status using genomic regions downstream to immunoglobulin rearrangements
N. McCafferty, J. Stewart, N. Darzentas, J. Gazdová +4 more
2022Haematologica6 citations Open access
Semantic Scholar
Potential and pitfalls of whole transcriptome-based immunogenetic marker identification in acute lymphoblastic leukemia; a EuroMRD and EuroClonality-NGS Working Group study
V. V. D. van der Velden, M. Brüggemann, G. Cazzaniga, B. Scheijen +8 more
2021Leukemia6 citations Open access
Semantic Scholar
Next-Generation Sequencing Technology to Identify Minimal Residual Disease in Lymphoid Malignancies.
M. Kotrová, N. Darzentas, C. Pott, M. Brüggemann
2021Methods in molecular biology6 citations
Semantic Scholar
ARResT/Interrogate Immunoprofiling Platform: Concepts, Workflows, and Insights.
N. Darzentas
2022Methods in molecular biology5 citations Open access
Semantic Scholar
Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia
P. M. Kolijn, Alice F. Muggen, V. Ljungström, A. Agathangelidis +9 more
2021Frontiers in Oncology5 citations Open access
Semantic Scholar
International multi-laboratory next-generation sequencing for MRD analysis in ALL. A pilot study by the Euroclonality-NGS consortium
M. Brüggemann, H. Knecht, J. Bartram, V. Bystrý +17 more
20155 citations
Semantic Scholar
Use of immune repertoire sequencing to resolve discordant microscopic and immunochemical findings in a case of T cell-rich large B cell lymphoma in a young dog
G. K. C. Lee, D. Bienzle, S. Keller, Mei-Hua Hwang +5 more
2021BMC Veterinary Research4 citations Open access
Semantic Scholar

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