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Christine S. L. Lee · SciRah

Researcher profile · Semantic Scholar

Christine S. L. Lee

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Christine S. L. Lee — researcher profile on SciRah

h-index: 23
Works: 39
Citations: 2,381

Most-cited papers

Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle.
E. Musgrove, Christine S. L. Lee, M. F. Buckley, Robert L. Sutherland
1994Proceedings of the National Academy of Sciences of the United States of America412 citations Open access
Semantic Scholar
Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression.
E. Musgrove, J. A. Hamilton, Christine S. L. Lee, K. J. Sweeney +2 more
1993Molecular and Cellular Biology317 citations Open access
Semantic Scholar
Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes
E. Musgrove, Christine S. L. Lee, R. Sutherland
1991Molecular and Cellular Biology250 citations Open access
Semantic Scholar
Cyclin E2 Overexpression Is Associated with Endocrine Resistance but not Insensitivity to CDK2 Inhibition in Human Breast Cancer Cells
C. E. Caldon, C. M. Sergio, Jian Kang, A. Muthukaruppan +11 more
2012Molecular Cancer Therapeutics149 citations Open access
Semantic Scholar
Mechanisms of Cyclin-Dependent Kinase Inactivation by Progestins
E. Musgrove, A. Swarbrick, Christine S. L. Lee, A. L. Cornish +1 more
1998Molecular and Cellular Biology131 citations Open access
Semantic Scholar
Constitutive overexpression of cyclin D1 but not cyclin E confers acute resistance to antiestrogens in T-47D breast cancer cells.
R. Hui, Georgina L Finney, J. Carroll, Christine S. L. Lee +2 more
2002Cancer Research124 citations
Semantic Scholar
EMS1 amplification can occur independently of CCND1 or INT-2 amplification at 11q13 and may identify different phenotypes in primary breast cancer
R. Hui, Douglas H. Campbell, Christine S. L. Lee, K. McCaul +5 more
1997Oncogene104 citations
Semantic Scholar
Steroid hormone receptor gene expression in human breast cancer cells: Inverse relationship between oestrogen and glucocorticoid receptor messenger RNA levels
R. E. Hall, Christine S. L. Lee, Ian E. Alexander, J. Shine +2 more
1990International Journal of Cancer81 citations
Semantic Scholar
Expression of the cyclin‐dependent kinase inhibitors p16INK4, p15INK4B and p21Waf1/cip1 in human breast cancer
E. Musgrove, Richard Liuschkis, A. L. Cornish, Christine S. L. Lee +3 more
1995International Journal of Cancer77 citations
Semantic Scholar
Regulation of cyclin expression and cell cycle progression in breast epithelial cells by the helix–loop–helix protein Id1
A. Swarbrick, M. C. Åkerfeldt, Christine S. L. Lee, C. M. Sergio +4 more
2005Oncogene75 citations
Semantic Scholar
Antiprogestin inhibition of cell cycle progression in T-47D breast cancer cells is accompanied by induction of the cyclin-dependent kinase inhibitor p21.
E. Musgrove, Christine S. L. Lee, A. L. Cornish, Alexander Swarbrick +1 more
1997Molecular Endocrinology70 citations Open access
Semantic Scholar
Effect of sodium butyrate on estrogen receptor and epidermal growth factor receptor gene expression in human breast cancer cell lines.
A. deFazio, Y. Chiew, C. Donoghue, Christine S. L. Lee +1 more
1992Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Cooperation of p27Kip1 and p18INK4c in Progestin-Mediated Cell Cycle Arrest in T-47D Breast Cancer Cells
A. Swarbrick, Christine S. L. Lee, R. Sutherland, E. Musgrove
2000Molecular and Cellular Biology61 citations Open access
Semantic Scholar
Cyclin D1 Overexpression Induces Progestin Resistance in T-47D Breast Cancer Cells Despite p27Kip1 Association with Cyclin E-Cdk2*
E. Musgrove, L. J. Hunter, Christine S. L. Lee, A. Swarbrick +2 more
2001Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Regulation of epidermal growth factor receptor by progestins and glucocorticoids in human breast cancer cell lines
T. Ewing, L. J. Murphy, M. Ng, Grace Y. N. Pang +3 more
1989International Journal of Cancer54 citations
Semantic Scholar
Global characterization of signalling networks associated with tamoxifen resistance in breast cancer
B. Browne, F. Hochgräfe, Jian-Min Wu, E. Millar +17 more
2013The FEBS Journal43 citations
Semantic Scholar
Modulation of estrogen receptor and epidermal growth factor receptor mRNAs by phorbol ester in MCF 7 breast cancer cells.
Christine S. L. Lee, Masafumi Koga, Robert L. Sutherland
1989Biochemical and Biophysical Research Communications - BBRC43 citations
Semantic Scholar
Regulation of breast cancer cell cycle progression by growth factors, steroids and steroid antagonists.
R. Sutherland, Christine S. L. Lee, Romy S. Feldman, E. Musgrove
1992Journal of Steroid Biochemistry and Molecular Biology41 citations
Semantic Scholar
The helix-loop-helix protein Id1 requires cyclin D1 to promote the proliferation of mammary epithelial cell acini.
C. E. Caldon, A. Swarbrick, Christine S. L. Lee, R. Sutherland +1 more
2008Cancer Research31 citations Open access
Semantic Scholar
Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells
Samuel Rogers, B. Gloss, Christine S. L. Lee, C. M. Sergio +4 more
2015Cell Division27 citations Open access
Semantic Scholar
Inverse relationship between estrogen receptor and epidermal growth factor receptor mRNA levels in human breast cancer cell lines.
Christine S. L. Lee, R. E. Hall, Ian E. Alexander, Masafumi Koga +2 more
1990Growth Factors26 citations
Semantic Scholar
Cyclin E2 Promotes Whole Genome Doubling in Breast Cancer
Christine S. L. Lee, Kristine J. Fernandez, Sarah Alexandrou, C. M. Sergio +4 more
2020Cancers25 citations Open access
Semantic Scholar
The cyclin-dependent kinase inhibitor p27 (Kip1) regulates both DNA synthesis and apoptosis in mammary epithelium but is not required for its functional development during pregnancy.
E. A. Davison, Christine S. L. Lee, Matthew J. Naylor, S. Oakes +4 more
2003Molecular Endocrinology23 citations Open access
Semantic Scholar
Inverse regulation of oestrogen receptor and epidermal growth factor receptor gene expression in MCF-7 breast cancer cells treated with phorbol ester.
Christine S. L. Lee, A. deFazio, C. Ormandy, R. Sutherland
1996Journal of Steroid Biochemistry and Molecular Biology22 citations
Semantic Scholar
Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition
Diar Aziz, N. Portman, Kristine J. Fernandez, Christine S. L. Lee +13 more
2021npj Breast Cancer21 citations Open access
Semantic Scholar
Amplification, expression, and steroid regulation of the preprogalanin gene in human breast cancer.
C. J. Ormandy, Christine S. L. Lee, Helen F. Ormandy, V. Fantl +3 more
1998Cancer Research20 citations
Semantic Scholar
T-47d Breast Cancer Cells Progestin-mediated Cell Cycle Arrest in in Ink4c and P18 Kip1 Cooperation of P27
Sutherland, E. Musgrove, A. Swarbrick, Christine S. L. Lee +1 more
20008 citations
Semantic Scholar
Regulation of prolactin receptor expression by the tumour promoting phorbol ester 12‐O‐tetradecanoylphorbol‐13‐acetate in human breast cancer cells
C. J. Ormandy, Christine S. L. Lee, Paul A. Kelly, Robert L. Sutherland
1993Journal of Cellular Biochemistry8 citations
Semantic Scholar
High cyclin E1 protein, but not gene amplification, is prognostic for basal‐like breast cancer
Diar Aziz, Christine S. L. Lee, Venessa T. Chin, Kristine J. Fernandez +3 more
2022The Journal of Pathology: Clinical Research7 citations Open access
Semantic Scholar
Cyclin E1 protein is stabilized in BRCA1 mutated breast cancers leading to synergy between CDK2 and PARP inhibitors
Diar Aziz, N. Portman, Kristine J. Fernandez, Christine S. L. Lee +13 more
2020bioRxiv3 citations Open access
Semantic Scholar
T-47D Breast Cancer Cells Progestin-Mediated Cell Cycle Arrest in in INK4c and p18 Kip1 Cooperation of p27
E. Musgrove, A. Swarbrick, Christine S. L. Lee, L. Robert
20143 citations
Semantic Scholar
in Patients with Features of Good Prognosis1
Ram Seshadri, Christine S. L. Lee, Rina Hui, Kieran Mccaul +4 more
20052 citations
Semantic Scholar
Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition
Diar Aziz, N. Portman, Kristine J. Fernandez, Christine S. L. Lee +13 more
2021npj Breast Cancer1 citations Open access
Semantic Scholar
S phase dysregulation occurs following resistance to CDK4/6 inhibition ER+ breast cancer
Sarah Alexandrou, H. Milioli, N. Portman, Christine S. L. Lee +4 more
2019Oncology Abstracts0 citations Open access
Semantic Scholar
Mechanisms underlying uncontrolled genome doubling in breast cancer
Christine S. L. Lee, Samuel Rogers, Kristine J. Fernandez, Sarah Alexandrou +8 more
2019Oncology Abstracts0 citations
Semantic Scholar
Cyclin E1 is a shared biomarker of subsets of high grade serous ovarian cancer (HGSOC) and basal like breast cancer (BLBC)
Diar Aziz, Christine S. L. Lee, Venessa T. Chin, Kristine J. Fernandez +4 more
2019Annals of Oncology0 citations Open access
Semantic Scholar
9. CYCLIN-DEPENDENT KINASE INHIBITOR AS A POTENTIAL NOVEL THERAPEUTIC AGENT FOR PANCREATIC CANCER
A. Chou, A. Gill, Jian Kang, Christine S. L. Lee +7 more
20140 citations
Semantic Scholar
Inactivation by Progestins Mechanisms of Cyclin-Dependent Kinase
A. L. Cornish, R. Sutherland, E. Musgrove, A. Swarbrick +1 more
19970 citations
Semantic Scholar
Steroid and steroid antagonist regulation of cyclin D1 and c-myc gene expression in T-47D breast cancer cells
E. Musgrove, J. A. Hamilton, Christine S. L. Lee, K. J. Sweeney +2 more
19930 citations
Semantic Scholar

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C. E. Caldon×12
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C. M. Sergio×8
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