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W. Bickmore · SciRah

Researcher profile · Semantic Scholar

W. Bickmore

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W. Bickmore — researcher profile on SciRah

h-index: 79
Works: 251
Citations: 24K

Most-cited papers

Enhancers: five essential questions
L. Pennacchio, W. Bickmore, A. Dean, Marcelo Araujo da Nóbrega +1 more
2013Nature reviews genetics569 citations Open access
Semantic Scholar
A mechanism of cohesin‐dependent loop extrusion organizes zygotic genome architecture
Johanna Gassler, Hugo B. Brandão, Maxim Imakaev, Ilya M. Flyamer +5 more
2017bioRxiv361 citations Open access
Semantic Scholar
Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation
Nezha S. Benabdallah, I. Williamson, R. Illingworth, Lauren Kane +5 more
2019Molecules and Cells294 citations Open access
Semantic Scholar
Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells
Pierre Therizols, R. Illingworth, C. Courilleau, S. Boyle +2 more
2014Science286 citations Open access
Semantic Scholar
Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization
I. Williamson, Soizik Berlivet, Ragnhild Eskeland, S. Boyle +4 more
2014Genes & Development237 citations Open access
Semantic Scholar
Histone H3 globular domain acetylation identifies a new class of enhancers
M. M. Pradeepa, G. Grimes, Y. Kumar, Gabrielle Olley +3 more
2016Nature Genetics224 citations Open access
Semantic Scholar
An Overview of Genome Organization and How We Got There: from FISH to Hi-C
J. Fraser, I. Williamson, W. Bickmore, Josée Dostie
2015Microbiology and Molecular Reviews199 citations Open access
Semantic Scholar
Coolpup.py: versatile pile-up analysis of Hi-C data
Ilya M. Flyamer, R. Illingworth, W. Bickmore
2019bioRxiv184 citations Open access
Semantic Scholar
The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development
R. Illingworth, M. Moffat, Abigail R. Mann, D. Read +4 more
2015Genes & Development156 citations Open access
Semantic Scholar
Developmentally regulated Shh expression is robust to TAD perturbations
I. Williamson, Lauren Kane, Paul S. Devenney, Ilya M. Flyamer +5 more
2019Development144 citations Open access
Semantic Scholar
The Hierarchy of Transcriptional Activation: From Enhancer to Promoter.
D. Vernimmen, W. Bickmore
2015Trends in Genetics138 citations Open access
Semantic Scholar
A central role for canonical PRC1 in shaping the 3D nuclear landscape
S. Boyle, Ilya M. Flyamer, I. Williamson, Dipta Sengupta +2 more
2019bioRxiv136 citations Open access
Semantic Scholar
Cohesin is required for long-range enhancer action at the Shh locus
Lauren Kane, I. Williamson, Ilya M. Flyamer, Yatendra Kumar +3 more
2022Nature Structural & Molecular Biology125 citations Open access
Semantic Scholar
Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity
I. Williamson, L. Lettice, R. Hill, W. Bickmore
2016Development122 citations Open access
Semantic Scholar
PRC1 fine-tunes gene repression and activation to safeguard skin development and stem cell specification
Idan Cohen, Dejian Zhao, Carmit Bar, V. Valdes +8 more
2018Cell Stem Cell120 citations Open access
Semantic Scholar
Chromatin topology, condensates and gene regulation: shifting paradigms or just a phase?
Mustafa Mir, W. Bickmore, E. Furlong, Geeta J. Narlikar
2019Development107 citations Open access
Semantic Scholar
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5
Débora R. Sobreira, Amelia C. Joslin, Qi Zhang, I. Williamson +14 more
2021Science95 citations Open access
Semantic Scholar
DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency
K. McLaughlin, Ilya M. Flyamer, J. Thomson, Heidi K. Mjoseng +8 more
2019Cell Reports91 citations Open access
Semantic Scholar
Nuclear pore density controls heterochromatin reorganization during senescence
Charlene Boumendil, P. Hari, K. C. Olsen, J. Acosta +1 more
2018bioRxiv78 citations Open access
Semantic Scholar
Chromatin at the nuclear periphery and the regulation of genome functions
C. Lemaître, W. Bickmore
2015Histochemistry and Cell Biology69 citations Open access
Semantic Scholar
Enhancer turnover is associated with a divergent transcriptional response to glucocorticoid in mouse and human macrophages
A. Jubb, Robert S. Young, D. Hume, W. Bickmore
2015Journal of Immunology65 citations Open access
Semantic Scholar
The frequent evolutionary birth and death of functional promoters in mouse and human
Robert S. Young, Y. Hayashizaki, Robin Andersson, A. Sandelin +7 more
2015Genome Research64 citations Open access
Semantic Scholar
Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction
Stefano Gnan, Ilya M. Flyamer, Kyle N. Klein, E. Castelli +9 more
2019Nature Communications55 citations Open access
Semantic Scholar
Repo-Man/PP1 regulates heterochromatin formation in interphase
Ines J. de Castro, James Budzak, M. D. Di Giacinto, Lorena Ligammari +15 more
2017Nature Communications53 citations Open access
Semantic Scholar
Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers
Robert S. Young, Y. Kumar, W. Bickmore, Martin S. Taylor
2017Genome Biology52 citations Open access
Semantic Scholar
Glucocorticoid Receptor Binding Induces Rapid and Prolonged Large-Scale Chromatin Decompaction at Multiple Target Loci
A. Jubb, S. Boyle, D. Hume, W. Bickmore
2017Cell Reports51 citations Open access
Semantic Scholar
Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer
Sehrish Rafique, Jeremy Thomas, D. Sproul, W. Bickmore
2015Genome Biology50 citations Open access
Semantic Scholar
Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability
Jessica Woodward, G. Taylor, D. Soares, S. Boyle +15 more
2016Genes & Development46 citations Open access
Semantic Scholar
Ultra-long-range interactions between active regulatory elements
Elias T. Friman, Ilya M. Flyamer, D. Marenduzzo, S. Boyle +1 more
2022bioRxiv44 citations Open access
Semantic Scholar
Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells
Donncha S. Dunican, Heidi K. Mjoseng, L. Duthie, Ilya M. Flyamer +2 more
2020BMC Biology43 citations Open access
Semantic Scholar
A Hox-Embedded Long Noncoding RNA: Is It All Hot Air?
L. Selleri, M. Bartolomei, W. Bickmore, Lin He +3 more
2016PLoS Genetics42 citations Open access
Semantic Scholar
Oncogene expression from extrachromosomal DNA is driven by copy number amplification and does not require spatial clustering in glioblastoma stem cells
K. Purshouse, Elias T. Friman, S. Boyle, P. Dewari +7 more
2022bioRxiv36 citations Open access
Semantic Scholar
Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression
Frederic Li Mow Chee, Bruno Beernaert, B. Griffith, Alexander E. P. Loftus +13 more
2023Nature Communications35 citations Open access
Semantic Scholar
Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins
M. M. Pradeepa, G. Grimes, G. Taylor, Heidi G. E. Sutherland +1 more
2014Nucleic Acids Research35 citations Open access
Semantic Scholar
Polycomb enables primitive endoderm lineage priming in embryonic stem cells
R. Illingworth, J. Hölzenspies, Fabian Roske, W. Bickmore +1 more
2016eLife34 citations Open access
Semantic Scholar
Transcription decouples estrogen-dependent changes in enhancer-promoter contact frequencies and spatial proximity
L. Gomez-Acuña, Ilya M. Flyamer, S. Boyle, Elias T. Friman +1 more
2023bioRxiv33 citations Open access
Semantic Scholar
Regulatory Domains and Their Mechanisms.
Nezha S. Benabdallah, W. Bickmore
2015Cold Spring Harbor Symposia on Quantitative Biology33 citations Open access
Semantic Scholar
Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo
Samantha Laber, S. Forcisi, L. Bentley, J. Petzold +22 more
2021Science Advances32 citations Open access
Semantic Scholar
Cohesin is required for long-range enhancer action
Lauren Kane, I. Williamson, Ilya M. Flyamer, Y. Kumar +3 more
2021bioRxiv30 citations Open access
Semantic Scholar
Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip
M. M. Pradeepa, F. McKenna, G. Taylor, Hemant Bengani +4 more
2017PLoS Genetics30 citations Open access
Semantic Scholar
PARP mediated chromatin unfolding is coupled to long-range enhancer activation
Nezha S. Benabdallah, I. Williamson, R. Illingworth, S. Boyle +3 more
2017bioRxiv25 citations Open access
Semantic Scholar
Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect
Gabrielle Olley, M. M. Pradeepa, G. Grimes, S. Piquet +4 more
2021Nature Communications24 citations Open access
Semantic Scholar
SBE6: a novel long-range enhancer involved in driving sonic hedgehog expression in neural progenitor cells
Nezha S. Benabdallah, P. Gautier, Betül Hekimoglu-Balkan, L. Lettice +2 more
2016Open Biology22 citations Open access
Semantic Scholar
Quantitative spatial and temporal assessment of regulatory element activity in zebrafish
Shipra Bhatia, D. Kleinjan, Kirsty Uttley, A. Mann +2 more
2021eLife21 citations Open access
Semantic Scholar
EvoChromo: towards a synthesis of chromatin biology and evolution
I. Drinnenberg, F. Berger, S. Elsässer, Peter R Andersen +24 more
2019Development17 citations Open access
Semantic Scholar
Recent advances in the spatial organization of the mammalian genome
Y. Kumar, Dipta Sengupta, W. Bickmore
2020Journal of Biosciences15 citations
Semantic Scholar
Reed-Sternberg Cells Form by Abscission Failure in the Presence of Functional Aurora B Kinase
Ana Xavier de Carvalho, H. Maiato, André F. Maia, S. Ribeiro +4 more
2015PLoS ONE14 citations Open access
Semantic Scholar
Fine-mapping and cell-specific enrichment at corneal resistance factor loci prioritize candidate causal regulatory variants
Xin-Yi Jiang, Nefeli Dellepiane, E. Pairo-Castineira, T. Boutin +3 more
2020Communications Biology13 citations Open access
Semantic Scholar
Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops
I. Williamson, S. Boyle, G. Grimes, Elias T. Friman +1 more
2023Life Science Alliance12 citations Open access
Semantic Scholar
Patterns in the genome
W. Bickmore
2019Heredity12 citations Open access
Semantic Scholar

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I. Williamson — researcher profile on SciRah
Ilya M. Flyamer×11
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