Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

M. Geyer · SciRah

Researcher profile · Semantic Scholar

M. Geyer

Share profile

M. Geyer — researcher profile on SciRah

h-index: 63
Works: 211
Citations: 13K

Most-cited papers

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease
C. Venegas, Sathish Kumar, B. Franklin, T. Dierkes +15 more
2017Nature899 citations Open access
Semantic Scholar
Rational discovery of molecular glue degraders via scalable chemical profiling
Cristina Mayor-Ruiz, Sophie Bauer, M. Brand, Z. Kozicka +15 more
2020Nature Chemical Biology322 citations Open access
Semantic Scholar
Covalent targeting of remote cysteine residues to develop CDK12 and 13 inhibitors
Ting-Hu Zhang, Nicholas Kwiatkowski, C. Olson, S. Dixon-Clarke +15 more
2016Nature Chemical Biology312 citations Open access
Semantic Scholar
NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain
Andrea Stutz, C. Kolbe, Rainer Stahl, Gabor L. Horvath +6 more
2017Journal of Experimental Medicine296 citations Open access
Semantic Scholar
Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3
Inga V. Hochheiser, M. Pilsl, G. Hagelueken, Jonas Moecking +5 more
2022Nature272 citations Open access
Semantic Scholar
CDK12 INHIBITION REVERSES DE NOVO AND ACQUIRED PARP INHIBITOR RESISTANCE IN BRCA WILD-TYPE AND MUTATED MODELS OF TRIPLE-NEGATIVE BREAST CANCER
Shawn F. Johnson, C. Cruz, A. K. Greifenberg, S. Dust +24 more
2016Cell Reports262 citations Open access
Semantic Scholar
Formins as effector proteins of Rho GTPases
Sonja Kühn, M. Geyer
2014Small GTPases262 citations Open access
Semantic Scholar
CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation
M. Krajewska, Ruben Dries, A. Grassetti, S. Dust +16 more
2018Nature Communications244 citations Open access
Semantic Scholar
Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation
Friederike Itzen, A. K. Greifenberg, Christian A. Bösken, M. Geyer
2014Nucleic Acids Research239 citations Open access
Semantic Scholar
The structure and substrate specificity of human Cdk12/Cyclin K
C. A. Bösken, L. Farnung, Corinna Hintermair, Miriam Merzel Schachter +6 more
2014Nature Communications186 citations Open access
Semantic Scholar
1,6-Hexanediol, commonly used to dissolve liquid–liquid phase separated condensates, directly impairs kinase and phosphatase activities
Robert Düster, I. Kaltheuner, M. Schmitz, M. Geyer
2021Journal of Biological Chemistry184 citations Open access
Semantic Scholar
β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
L. Friker, H. Scheiblich, Inga V. Hochheiser, Rebecca Brinkschulte +4 more
2020Cell Reports167 citations Open access
Semantic Scholar
Development of a selective CDK7 covalent inhibitor reveals predominant cell cycle phenotype
C. Olson, Yanke Liang, Alan L. Leggett, W. D. Park +14 more
2019Cell Chemical Biology147 citations Open access
Semantic Scholar
CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells.
Matthias G. Braun, Amelia Roman Aguilera, Ashmitha Sundarrajan, Dillon Corvino +45 more
2020Immunity142 citations Open access
Semantic Scholar
P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates
M. Sansó, Rebecca S. Levin, Jesse J. Lipp, V. Wang +10 more
2016Genes & Development137 citations Open access
Semantic Scholar
Structural and Functional Analysis of the Cdk13/Cyclin K Complex.
A. K. Greifenberg, Dana Hönig, Květa Pilařová, Robert Düster +5 more
2016Cell Reports135 citations Open access
Semantic Scholar
Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex
Kingsley M. Ekumi, Hana Paculová, Tina Lenasi, Vendula Pospíchalová +6 more
2015Nucleic Acids Research134 citations Open access
Semantic Scholar
FMNL formins boost lamellipodial force generation
Frieda Kage, M. Winterhoff, V. Dimchev, Jan Mueller +15 more
2017Nature Communications133 citations Open access
Semantic Scholar
CDK13 cooperates with CDK12 to control global RNA polymerase II processivity
Zheng Fan, J. Devlin, S. Hogg, M. Doyle +17 more
2020Science Advances132 citations Open access
Semantic Scholar
MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation
Apoorva Baluapuri, Julia Hofstetter, Nevenka Dudvarski-Stankovic, Theresa Endres +19 more
2019Molecules and Cells119 citations Open access
Semantic Scholar
Discovery and Resistance Mechanism of a Selective CDK12 Degrader
Bai-Shan Jiang, Yang Gao, Jian-Wei Che, Wenchao Lu +13 more
2021Nature Chemical Biology116 citations Open access
Semantic Scholar
Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation.
L. Jaenicke, Björn von Eyss, Anne Carstensen, E. Wolf +5 more
2016Molecules and Cells95 citations Open access
Semantic Scholar
Deficiency in coatomer complex I causes aberrant activation of STING signalling
A. Steiner, K. Hrovat-Schaale, I. Prigione, Chien-Hsiung Yu +15 more
2022Nature Communications91 citations Open access
Semantic Scholar
Global mapping of Salmonella enterica-host protein-protein interactions during infection
Philipp Walch, J. Selkrig, L. Knodler, M. Rettel +11 more
2020bioRxiv81 citations Open access
Semantic Scholar
Mechanisms of NLRP1-Mediated Autoinflammatory Disease in Humans and Mice.
Chien-Hsiung Yu, Jonas Moecking, M. Geyer, S. Masters
2018Journal of Molecular Biology80 citations
Semantic Scholar
Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex.
M. Romano, A. Tafazzoli, M. Mattern, S. Sivalingam +18 more
2018American Journal of Human Genetics79 citations Open access
Semantic Scholar
P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress
A. Bugai, Alexandre J. C. Quaresma, C. Friedel, Tina Lenasi +10 more
2018bioRxiv78 citations Open access
Semantic Scholar
Nef Proteins of Epidemic HIV-1 Group O Strains Antagonize Human Tetherin
Silvia F. Kluge, Katharina Mack, S. Iyer, F. Pujol +14 more
2014Cell Host and Microbe77 citations Open access
Semantic Scholar
Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription
Jenna K. Rimel, Z. Poss, Benjamin Erickson, Zachary L. Maas +25 more
2020Genes & Development76 citations Open access
Semantic Scholar
The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo
S. Jostes, D. Nettersheim, Martin Fellermeyer, S. Schneider +6 more
2016Journal of Cellular and Molecular Medicine76 citations Open access
Semantic Scholar
The structure of FMNL2–Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation
Sonja Kühn, Constanze Erdmann, Frieda Kage, J. Block +4 more
2015Nature Communications71 citations Open access
Semantic Scholar
Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation
Inga V. Hochheiser, Heide Behrmann, G. Hagelueken, J. Rodríguez-Alcázar +4 more
2021bioRxiv68 citations Open access
Semantic Scholar
SOCS1 and SOCS3 Target IRF7 Degradation To Suppress TLR7-Mediated Type I IFN Production of Human Plasmacytoid Dendritic Cells
Chunfeng Yu, Wen-Ming Peng, M. Schlee, W. Barchet +7 more
2018Journal of Immunology67 citations Open access
Semantic Scholar
LAMP-Seq: Sensitive, Scalable, and Multiplexable COVID-19 Diagnostics Using Molecular Barcoding
K. Ludwig, R. Schmithausen, David Li, Max L. Jacobs +36 more
2021Nature Biotechnology65 citations Open access
Semantic Scholar
Alternative splicing regulates stochastic NLRP3 activity
Florian Hoss, J. Mueller, Francisca Rojas Ringeling, J. Rodríguez-Alcázar +10 more
2019Nature Communications64 citations Open access
Semantic Scholar
FHOD1 regulates stress fiber organization by controlling the dynamics of transverse arcs and dorsal fibers
Nina Schulze, Melanie Graessl, Alexandra Blancke Soares, M. Geyer +2 more
2014Journal of Cell Science64 citations Open access
Semantic Scholar
ATP-binding and hydrolysis of human NLRP3
Rebecca Brinkschulte, David M. Fußhöller, Florian Hoss, J. Rodríguez-Alcázar +7 more
2022Communications Biology59 citations Open access
Semantic Scholar
Oncogenic CDK13 Mutations Impede Nuclear RNA Surveillance
Megan L. Insco, B. Abraham, S. Dubbury, I. Kaltheuner +21 more
2023Science57 citations Open access
Semantic Scholar
HIV protein Nef causes dyslipidemia and formation of foam cells in mouse models of atherosclerosis
H. Cui, M. Ditiatkovski, Rajitha Kesani, Y. Bobryshev +5 more
2014The FASEB Journal56 citations Open access
Semantic Scholar
Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma.
Bai-Shan Jiang, Jie Jiang, I. Kaltheuner, A. Iniguez +12 more
2021European journal of medicinal chemistry53 citations Open access
Semantic Scholar
Antiviral signalling by a cyclic nucleotide activated CRISPR protease
C. Rouillon, N. Schneberger, Haotian Chi, Katja Blumenstock +12 more
2022Nature48 citations Open access
Semantic Scholar
The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21
Lucia A. Torres-Fernández, B. Jux, Maximilian Bille, Yasmine Port +4 more
2019Nucleic Acids Research48 citations Open access
Semantic Scholar
Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation
I. Kaltheuner, K. Anand, Jonas Moecking, Robert Düster +3 more
2021Nature Communications43 citations Open access
Semantic Scholar
Down‐regulation of CD73 on B cells of patients with viremic HIV correlates with B cell activation and disease progression
Eun-seong Kim, C. Ackermann, I. Tóth, P. Dierks +10 more
2017Journal of Leukocyte Biology31 citations Open access
Semantic Scholar
Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3
Santiago Manrique, D. Sauter, F. Horenkamp, Sebastian Lülf +5 more
2017Nature Communications31 citations Open access
Semantic Scholar
Pyroptosis inhibiting nanobodies block Gasdermin D pore formation
Anja Kopp, G. Hagelueken, Isabell Jamitzky, Jonas Moecking +3 more
2023bioRxiv28 citations Open access
Semantic Scholar
Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus
A. Steiner, T. Reygaerts, Alessandra Pontillo, I. Ceccherini +16 more
2021Journal of Clinical Immunology28 citations Open access
Semantic Scholar
CDK13 cooperates with CDK12 to control global RNA polymerase II processivity
Zheng Fan, J. Devlin, S. Hogg, M. Doyle +17 more
2020Science Advances25 citations Open access
Semantic Scholar
Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly.
M. Marleaux, K. Anand, E. Latz, M. Geyer
2020FEBS Letters24 citations Open access
Semantic Scholar
Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter
M. Peter, J. A. Ruland, Peer Depping, N. Schneberger +13 more
2022Nature Communications23 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

E. Latz×8
Invite
E. Latz — researcher profile on SciRah
I. Kaltheuner×8
Invite
I. Kaltheuner — researcher profile on SciRah
N. Gray×8
Invite
N. Gray — researcher profile on SciRah
Nicholas Kwiatkowski×7
Invite
Nicholas Kwiatkowski — researcher profile on SciRah

A. K. Greifenberg

×7

Invite

A. K. Greifenberg — researcher profile on SciRah

Jonas Moecking×7

Invite

Jonas Moecking — researcher profile on SciRah

Rebecca Brinkschulte×6

Invite

Rebecca Brinkschulte — researcher profile on SciRah

Invite

K. Anand — researcher profile on SciRah

Ting-Hu Zhang×5

Invite

Ting-Hu Zhang — researcher profile on SciRah

G. Hagelueken×5

Invite

G. Hagelueken — researcher profile on SciRah

Robert Düster×5

Invite

Robert Düster — researcher profile on SciRah

Invite

S. Dust — researcher profile on SciRah