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H. Akil · SciRah

Researcher profile · Semantic Scholar

H. Akil

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H. Akil — researcher profile on SciRah

h-index: 111
Works: 518
Citations: 51K

Most-cited papers

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
S. H. S. B. M. S. V. S. M. R. H. B. Lee Ripke Neale Faraone Purcell Perlis Mowry Thapa, Hong S. Lee, S. Ripke, B. Neale +367 more
2013Nature Genetics2,210 citations Open access
Semantic Scholar
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
Colm Lizzy Phil H Laramie Neelroop N Stephen Stephan Be O'Dushlaine Rossin Lee Duncan Parikshak Newhouse R, C. O'Dushlaine, L. Rossin, P. Lee +372 more
2015Nature Neuroscience765 citations Open access
Semantic Scholar
Rare coding variants in 10 genes confer substantial risk for schizophrenia
T. Singh, T. Poterba, D. Curtis, H. Akil +107 more
2022Nature687 citations Open access
Semantic Scholar
Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes
D. Ruderfer, S. Ripke, A. McQuillin, J. Boocock +496 more
2018Cell675 citations Open access
Semantic Scholar
Circadian patterns of gene expression in the human brain and disruption in major depressive disorder
Jun Z. Li, B. Bunney, F. Meng, M. Hagenauer +12 more
2013Proceedings of the National Academy of Sciences of the United States of America587 citations Open access
Semantic Scholar
Revisiting the Stress Concept: Implications for Affective Disorders
B. McEwen, H. Akil
2020Journal of Neuroscience518 citations Open access
Semantic Scholar
Treatment Resistant Depression: A Multi-Scale, Systems Biology Approach
H. Akil, J. Gordon, R. Hen, J. Javitch +4 more
2017Neuroscience and Biobehavioral Reviews407 citations Open access
Semantic Scholar
Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder
R. Maier, G. Moser, Guo-Bo Chen, S. Ripke +373 more
2015American Journal of Human Genetics226 citations Open access
Semantic Scholar
Post-mortem molecular profiling of three psychiatric disorders
R. Ramaker, K. Bowling, Brittany N. Lasseigne, M. Hagenauer +16 more
2016Genome Medicine197 citations Open access
Semantic Scholar
Experiment 1 : Are there Pre-Existing Differences in Conditioned Approach Behavior in Rats Susceptible to Obesity Under Ad Lib Conditions ?
M. J. Robinson, P. Burghardt, C. Patterson, Cameron W. Nobile +4 more
2015181 citations
Semantic Scholar
The critical importance of basic animal research for neuropsychiatric disorders
T. Bale, T. Abel, H. Akil, W. Carlezon +4 more
2019Neuropsychopharmacology131 citations Open access
Semantic Scholar
ANTECEDENTS AND CONSEQUENCES OF DRUG ABUSE IN RATS SELECTIVELY BRED FOR HIGH AND LOW RESPONSE TO NOVELTY
S. Flagel, M. Waselus, S. Clinton, S. Watson +1 more
2013Neuropharmacology130 citations Open access
Semantic Scholar
Analysis of miR-137 Expression and rs1625579 in Dorsolateral Prefrontal Cortex
I. Guella, A. Sequeira, B. Rollins, L. Morgan +11 more
2013Journal of Psychiatric Research125 citations Open access
Semantic Scholar
Evidence for alterations of the glial syncytial function in Major Depressive Disorder
A. Medina, S. Watson, W. Bunney, R. Myers +4 more
2015Journal of Psychiatric Research103 citations Open access
Semantic Scholar
The microRNA network is altered in anterior cingulate cortex of patients with unipolar and bipolar depression
Joshua A. Azevedo, Bradley S. Carter, F. Meng, D. Turner +9 more
2016Journal of Psychiatric Research76 citations Open access
Semantic Scholar
Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis
M. Hagenauer, Anton Schulmann, Jun Z. Li, M. Vawter +9 more
2018PLoS ONE75 citations Open access
Semantic Scholar
G protein-linked signaling pathways in bipolar and major depressive disorders
Hiroaki Tomita, Mary E. Ziegler, Helen B. Kim, S. Evans +14 more
2013Frontiers in Genetics75 citations Open access
Semantic Scholar
Dysregulated fibroblast growth factor (FGF) signaling in neurological and psychiatric disorders
Cortney A. Turner, E. Eren-Koçak, E. Inui, S. Watson +1 more
2015Seminars in Cell and Developmental Biology65 citations Open access
Semantic Scholar
High Novelty-Seeking Rats Are Resilient to Negative Physiological Effects of the Early Life Stress
S. Clinton, S. Watson, H. Akil
2013Stress65 citations Open access
Semantic Scholar
Neuroscience Training for the 21st Century.
H. Akil, R. Balice-Gordon, D. L. Cardozo, W. Koroshetz +4 more
2016Neuron63 citations Open access
Semantic Scholar
Glutamate transporters: a key piece in the glutamate puzzle of major depressive disorder.
A. Medina, S. Burke, Robert C. Thompson, W. Bunney +4 more
2013Journal of Psychiatric Research63 citations
Semantic Scholar
S100A8/A9 drives neuroinflammatory priming and protects against anxiety-like behavior after sepsis
S. Denstaedt, Joanna L. Spencer-Segal, M. Newstead, K. Laborc +6 more
2018Journal of Immunology62 citations Open access
Semantic Scholar
Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model
S. Flagel, S. Chaudhury, M. Waselus, Rebeca Kelly +5 more
2016Proceedings of the National Academy of Sciences of the United States of America61 citations Open access
Semantic Scholar
Lesions of the paraventricular nucleus of the thalamus differentially affect sign- and goal-tracking conditioned responses
Joshua L. Haight, Kurt M. Fraser, H. Akil, S. Flagel
2015European Journal of Neuroscience57 citations Open access
Semantic Scholar
Altered choroid plexus gene expression in major depressive disorder
Cortney A. Turner, Robert C. Thompson, W. Bunney, A. Schatzberg +4 more
2014Frontiers in Human Neuroscience55 citations Open access
Semantic Scholar
Endogenous Opioids at the Intersection of Opioid Addiction, Pain, and Depression: The Search for A Precision Medicine Approach
M. Emery, H. Akil
2020Annual Review of Neuroscience52 citations Open access
Semantic Scholar
Mitochondrial Mutations in Subjects with Psychiatric Disorders
A. Sequeira, B. Rollins, C. Magnan, M. van Oven +8 more
2015PLoS ONE52 citations Open access
Semantic Scholar
Fibroblast growth factor 9 is a novel modulator of negative affect
E. Aurbach, E. Inui, Cortney A. Turner, M. Hagenauer +11 more
2015Proceedings of the National Academy of Sciences of the United States of America52 citations Open access
Semantic Scholar
Uneven balance of power between hypothalamic peptidergic neurons in the control of feeding
Qiang Wei, D. Krolewski, S. Moore, Vivek Kumar +7 more
2018Proceedings of the National Academy of Sciences of the United States of America49 citations Open access
Semantic Scholar
FGF2 is a target and a trigger of epigenetic mechanisms associated with differences in emotionality: Partnership with H3K9me3
S. Chaudhury, E. Aurbach, Vikram Sharma, P. Blandino +3 more
2014Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
Semantic Scholar
Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder
Sujan C. Das, B. Hjelm, B. Rollins, A. Sequeira +10 more
2022Translational Psychiatry45 citations Open access
Semantic Scholar
Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence
B. Rollins, Ling Z. Morgan, B. Hjelm, A. Sequeira +9 more
2017Molecular Neuropsychiatry45 citations Open access
Semantic Scholar
Identification of potential blood biomarkers associated with suicide in major depressive disorder
F. Mamdani, Matthieu D. Weber, B. Bunney, Kathleen Burke +11 more
2022Translational Psychiatry42 citations Open access
Semantic Scholar
Characterizing the behavioral and neuroendocrine features of susceptibility and resilience to social stress
Dalia Murra, Kathryn L. Hilde, Anne Fitzpatrick, P. Maras +2 more
2021bioRxiv40 citations Open access
Semantic Scholar
Maternal Style Selectively Shapes Amygdalar Development and Social Behavior in Rats Genetically Prone to High Anxiety
Joshua L. Cohen, Matthew E. Glover, P. Pugh, Andrew D. Fant +4 more
2015Developmental Neuroscience36 citations Open access
Semantic Scholar
Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype
Zhi-Feng Zhou, P. Blandino, Q. Yuan, Pei-Hong Shen +5 more
2019Proceedings of the National Academy of Sciences of the United States of America34 citations Open access
Semantic Scholar
Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex
I. Guella, A. Sequeira, B. Rollins, Ling Z. Morgan +7 more
2013Schizophrenia Research32 citations Open access
Semantic Scholar
Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders
B. Hjelm, B. Rollins, Ling Z. Morgan, A. Sequeira +16 more
2019Nucleic Acids Research31 citations Open access
Semantic Scholar
Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats
M. García-Fuster, A. Parsegian, S. Watson, H. Akil +1 more
2017Psychopharmacology29 citations Open access
Semantic Scholar
Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders
Ling Z. Morgan, B. Rollins, A. Sequeira, W. Byerley +8 more
2016Microarrays28 citations Open access
Semantic Scholar
Glucocorticoids and resilience
Joanna L. Spencer-Segal, H. Akil
2018Hormones and Behavior27 citations Open access
Semantic Scholar
Male rats that differ in novelty exploration demonstrate distinct patterns of sexual behavior
Jennifer A. Cummings, S. Clinton, Adam N. Perry, H. Akil +1 more
2013Behavioral Neuroscience27 citations Open access
Semantic Scholar
Selectively Bred Rats Provide a Unique Model of Vulnerability to PTSD-Like Behavior and Respond Differentially to FGF2 Augmentation Early in Life
K. Prater, E. Aurbach, Hanna K Larcinese, Taylor N Smith +5 more
2017Neuropsychopharmacology25 citations Open access
Semantic Scholar
In vivo neurochemical profile of selectively bred high-responder and low-responder rats reveals baseline, cocaine- and novelty-evoked differences in monoaminergic systems
O. Mabrouk, Johnson Han, Jenny-Marie T. Wong, H. Akil +2 more
2017ACS Chemical Neuroscience25 citations Open access
Semantic Scholar
Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model
P. Maras, E. Hebda-Bauer, M. Hagenauer, Kathryn L. Hilde +3 more
2021bioRxiv23 citations Open access
Semantic Scholar
Revealing a latent variable: Individual differences in affective response to repeated injections
Cigdem Aydin, Karla S. Frohmader, H. Akil
2015Behavioral Neuroscience23 citations Open access
Semantic Scholar
Protective Effects of Chronic Mild Stress during Adolescence in the Low Novelty Responder Rat
Samir Rana, Hyungwoo Nam, Matthew E. Glover, H. Akil +3 more
2015Stress23 citations Open access
Semantic Scholar
Altered DNA Methylation in the Developing Brains of Rats Genetically Prone to High versus Low Anxiety
Chelsea R. McCoy, Matthew E. Glover, L. T. Flynn, Rebecca K. Simmons +7 more
2019Journal of Neuroscience22 citations Open access
Semantic Scholar
Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model
Isabelle A. Birt, M. Hagenauer, S. Clinton, Cigdem Aydin +13 more
2020Biological Psychiatry21 citations Open access
Semantic Scholar
Adaptation to single housing is dynamic: Changes in hormone levels, gene expression, signaling in the brain, and anxiety-like behavior in adult male C57Bl/6J mice
E. Hebda-Bauer, L. Dokas, S. Watson, H. Akil
2019Hormones and Behavior20 citations Open access
Semantic Scholar

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