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S. Harper · SciRah

Researcher profile · Semantic Scholar

S. Harper

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S. Harper — researcher profile on SciRah

h-index: 27
Works: 60
Citations: 2,609

Most-cited papers

Purification of proteins fused to glutathione S-tranferase
S. Harper, D. Speicher
2011Methods in molecular biology231 citations Open access
Semantic Scholar
Two‐Dimensional Gel Electrophoresis
S. Harper, J. Mozdzanowski, D. Speicher
1999Current Protocols in Cell Biology177 citations
Semantic Scholar
The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate
Yuan Yan, S. Harper, D. Speicher, R. Marmorstein
2002Nature Structural Biology174 citations
Semantic Scholar
Systematic analysis of peptide recoveries from in-gel digestions for protein identifications in proteome studies.
Kaye D. Speicher, Olivera Kolbas, S. Harper, D. Speicher
2000Journal of Biomolecular Techniques172 citations
Semantic Scholar
Cooperativity in forced unfolding of tandem spectrin repeats.
R. Law, Philippe Carl, S. Harper, P. Dalhaimer +2 more
2003Biophysical Journal158 citations Open access
Semantic Scholar
Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum.
Noel N. Kim, J. Cox, R. Baggio, Frances A. Emig +7 more
2001Biochemistry158 citations
Semantic Scholar
Biochemical Analysis of the Kruppel-associated Box (KRAB) Transcriptional Repression Domain
Hongzhuang Peng, Gillian E. Begg, S. Harper, J. Friedman +2 more
2000Journal of Biological Chemistry117 citations Open access
Semantic Scholar
Structural Basis for Dimerization in DNA Recognition by Gal4
Manqing Hong, M. X. Fitzgerald, S. Harper, C. Luo +2 more
2008Structure97 citations Open access
Semantic Scholar
Pathway shifts and thermal softening in temperature-coupled forced unfolding of spectrin domains.
R. Law, George Liao, S. Harper, Guoliang Yang +2 more
2003Biophysical Journal90 citations Open access
Semantic Scholar
Detection of Proteins on Blot Membranes
Aaron R. Goldman, S. Harper, D. Speicher
1995Current Protocols in Protein Science89 citations Open access
Semantic Scholar
PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma
Gaurav Sharma, R. Ojha, Estela Noguera-Ortega, Vito W. Rebecca +16 more
2020JCI Insight78 citations Open access
Semantic Scholar
Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex.
J. J. Ipsaro, S. Harper, T. Messick, R. Marmorstein +2 more
2010Blood72 citations Open access
Semantic Scholar
Structural and functional effects of hereditary hemolytic anemia-associated point mutations in the alpha spectrin tetramer site.
M. Gaetani, S. Mootien, S. Harper, P. Gallagher +1 more
2008Blood56 citations Open access
Semantic Scholar
Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity
Suiping Zhou, E. M. Sorokina, S. Harper, Haitao Li +5 more
2016Free Radical Biology & Medicine53 citations Open access
Semantic Scholar
Expression and purification of GST fusion proteins.
S. Harper, D. Speicher
1997Current Protocols in Protein Science50 citations
Semantic Scholar
Lysosomal lipid peroxidation regulates tumor immunity
M. Bhardwaj, J. J. Lee, Amanda M. Versace, S. Harper +12 more
2023Journal of Clinical Investigation49 citations Open access
Semantic Scholar
Chemistry on a Single Protein, Vascular Cell Adhesion Molecule-1, during Forced Unfolding*
Nishant Bhasin, Philippe Carl, S. Harper, Gang Feng +3 more
2004Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Cdc13 N-Terminal Dimerization, DNA Binding, and Telomere Length Regulation
M. Mitchell, Jasmine S. Smith, M. Mason, S. Harper +3 more
2010Molecular and Cellular Biology45 citations Open access
Semantic Scholar
Initiation of Spectrin Dimerization Involves Complementary Electrostatic Interactions between Paired Triple-helical Bundles*
Gillian E. Begg, S. Harper, M. B. Morris, D. Speicher
2000Journal of Biological Chemistry44 citations Open access
Semantic Scholar
CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer
Bipradeb Singha, S. Harper, Aaron R. Goldman, Benjamin G. Bitler +8 more
2018Scientific Reports42 citations Open access
Semantic Scholar
The Physiological Molecular Shape of Spectrin: A Compact Supercoil Resembling a Chinese Finger Trap
Jeffrey W. Brown, E. Bullitt, Sira Sriswasdi, S. Harper +2 more
2015PLoS Comput. Biol.41 citations Open access
Semantic Scholar
Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding.
Colin P. Johnson, M. Gaetani, V. Ortiz, Nishant Bhasin +4 more
2007Blood39 citations Open access
Semantic Scholar
The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain.
Hongzhuang Peng, L. Gibson, A. Capili, K. Borden +7 more
2007Journal of Molecular Biology34 citations
Semantic Scholar
Targeting UGCG overcomes resistance to lysosomal autophagy inhibition
Vaibhav Jain, S. Harper, Amanda M. Versace, Dylan Fingerman +12 more
2022Cancer Discovery33 citations Open access
Semantic Scholar
Cdc13 OB2 Dimerization Required for Productive Stn1 Binding and Efficient Telomere Maintenance
M. Mason, Jennifer J. Wanat, S. Harper, D. Schultz +3 more
2012Structure33 citations Open access
Semantic Scholar
Probing structures of large protein complexes using zero-length cross-linking
Roland F Rivera-Santiago, Sira Sriswasdi, S. Harper, D. Speicher
2015Methods31 citations Open access
Semantic Scholar
The common hereditary elliptocytosis-associated α-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation.
S. Harper, Sira Sriswasdi, Hsin-Yao Tang, M. Gaetani +2 more
2013Blood28 citations Open access
Semantic Scholar
A Comprehensive Model of the Spectrin Divalent Tetramer Binding Region Deduced Using Homology Modeling and Chemical Cross-linking of a Mini-spectrin*
Donghai Li, S. Harper, Hsin-Yao Tang, Y. Maksimova +2 more
2010Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Role of terminal nonhomologous domains in initiation of human red cell spectrin dimerization.
S. Harper, Gillian E. Begg, D. Speicher
2001Biochemistry27 citations
Semantic Scholar
The exon 46-encoded sequence is essential for stability of human erythroid alpha-spectrin and heterodimer formation.
Rick Wilmotte, S. Harper, J. Ursitti, J. Maréchal +2 more
1997Blood27 citations
Semantic Scholar
Influence of Lateral Association on Forced Unfolding of Antiparallel Spectrin Heterodimers*
R. Law, S. Harper, D. Speicher, D. Discher
2004Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Effect of glutathione on the phospholipase A2 activity of peroxiredoxin 6
Suiping Zhou, C. Dodia, T. Shuvaeva, Elena M. Sorokina +4 more
201324 citations
Semantic Scholar
Two‐Dimensional Gel Electrophoresis
S. Harper, J. Mozdzanowski, D. Speicher
1998Current Protocols in Protein Science23 citations
Semantic Scholar
Full-Length Anion Exchanger 1 Structure and Interactions with Ankyrin-1 Determined by Zero Length Crosslinking of Erythrocyte Membranes
Roland F Rivera-Santiago, S. Harper, Sira Sriswasdi, Peter Hembach +1 more
2016Structure22 citations Open access
Semantic Scholar
Probing large conformational rearrangements in wild-type and mutant spectrin using structural mass spectrometry
Sira Sriswasdi, S. Harper, Hsin-Yao Tang, P. Gallagher +1 more
2014Proceedings of the National Academy of Sciences of the United States of America22 citations Open access
Semantic Scholar
Enhanced identification of zero-length chemical crosslinks using label-free quantitation and high-resolution fragment ion spectra
Sira Sriswasdi, S. Harper, Hsin-Yao Tang, D. Speicher
2014Journal of Proteome Research22 citations Open access
Semantic Scholar
A Fused α-β “Mini-spectrin” Mimics the Intact Erythrocyte Spectrin Head-to-head Tetramer*
S. Harper, Donghai Li, Y. Maksimova, P. Gallagher +1 more
2010Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Proteome Analysis of the Triton-Insoluble Erythrocyte Membrane Skeleton
A. Basu, S. Harper, Esther N. Pesciotta, Kaye D. Speicher +2 more
2015Journal of Proteomics18 citations Open access
Semantic Scholar
Spectrin Tetramer Formation Is Not Required for Viable Development in Drosophila*
Mansi R. Khanna, Floyd J. Mattie, Kristen C. Browder, M. Radyk +5 more
2014Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Expression and Purification of GST Fusion Proteins
S. Harper, D. Speicher
1997Current Protocols in Protein Science17 citations
Semantic Scholar
Solution Structure of the Reduced Form of Human Peroxiredoxin-6 Elucidated Using Zero-Length Chemical Cross-linking And Homology Modeling
Roland F Rivera-Santiago, S. Harper, Suiping Zhou, Sira Sriwasdi +3 more
2015Biochemical Journal14 citations Open access
Semantic Scholar
Initiation and propagation of spectrin heterodimer assembly involves distinct energetic processes.
Donghai Li, S. Harper, D. Speicher
2007Biochemistry14 citations
Semantic Scholar
Oxidation of Peroxiredoxin 6 in the Presence of GSH Increases its Phospholipase A2 Activity at Cytoplasmic pH
Suiping Zhou, C. Dodia, S. Feinstein, S. Harper +3 more
2018Antioxidants10 citations Open access
Semantic Scholar
Characterizing Recombinant Proteins Using HPLC Gel Filtration and Mass Spectrometry
Gillian E. Begg, S. Harper, D. Speicher
1999Current Protocols in Protein Science10 citations
Semantic Scholar
PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma
Gopal Sharma, R. Ojha, Estela Noguera-Ortega, Vito W. Rebecca +16 more
2022JCI Insight9 citations Open access
Semantic Scholar
Detection of Proteins on Blot Membranes
S. Harper, D. Speicher
1995Current Protocols in Protein Science8 citations Open access
Semantic Scholar
UNIT 10.4 Comparing Complex Protein Samples Using Two-Dimensional Polyacrylamide Gels (orig pub 1998)
S. Harper, J. Mozdzanowski, D. Speicher
2019Current Protocols in Protein Science6 citations Open access
Semantic Scholar
UNIT 10.8 Detection of Proteins on Blot Membranes
S. Harper, D. Speicher
20016 citations Open access
Semantic Scholar
cDNA sequence of the human erythroid alpha-spectrin: identification of a base deletion in the sequence database.
L. Galluzzi, Mirko Paiardini, Mauro Magnani, G. Nicolas +3 more
1999Blood4 citations
Semantic Scholar
Identification and Characterization of α-Spectrin Mutations Associated with Inherited Hemolytic Anemia.
W. Tolpinrud, M. Gaetani, Y. Maksimova, S. Mootien +4 more
20072 citations
Semantic Scholar

Frequent co-authors

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D. Speicher×6
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