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A. Podtelezhnikov · SciRah

Researcher profile · Semantic Scholar

A. Podtelezhnikov

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A. Podtelezhnikov — researcher profile on SciRah

h-index: 23
Works: 49
Citations: 3,502

Most-cited papers

Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease
Bin Zhang, C. Gaiteri, L. Bodea, Zhi Wang +26 more
2013Cell1,690 citations Open access
Semantic Scholar
Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors.
I. Krop, T. Demuth, T. Guthrie, P. Wen +16 more
2012Journal of Clinical Oncology317 citations Open access
Semantic Scholar
Transcriptional Architecture of the Primate Neocortex
Amy Bernard, Laura S. Lubbers, K. Tanis, Rui Luo +20 more
2012Neuron224 citations Open access
Semantic Scholar
Mechanism of topology simplification by type II DNA topoisomerases
A. Vologodskii, Wentao Zhang, V. Rybenkov, A. Podtelezhnikov +3 more
2001Proceedings of the National Academy of Sciences of the United States of America152 citations Open access
Semantic Scholar
Comparative transcriptomics of choroid plexus in Alzheimer’s disease, frontotemporal dementia and Huntington’s disease: implications for CSF homeostasis
E. Stopa, K. Tanis, Miles C. Miller, E. Nikonova +12 more
2018Fluids and Barriers of the CNS98 citations Open access
Semantic Scholar
Large-scale effects of transcriptional DNA supercoiling in vivo.
A. S. Krasilnikov, A. Podtelezhnikov, A. Vologodskii, S. Mirkin
1999Journal of Molecular Biology93 citations
Semantic Scholar
Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation.
E. Arnardóttir, E. Nikonova, K. Shockley, A. Podtelezhnikov +7 more
2014Sleep88 citations Open access
Semantic Scholar
Molecular Insights into the Pathogenesis of Alzheimer's Disease and Its Relationship to Normal Aging
A. Podtelezhnikov, K. Tanis, M. Nebozhyn, W. J. Ray +2 more
2011PLoS ONE78 citations Open access
Semantic Scholar
Discovering biology in periodic data through phase set enrichment analysis (PSEA)
Ray Zhang, A. Podtelezhnikov, J. Hogenesch, Ron C. Anafi
2016Journal of Biological Rhythms71 citations Open access
Semantic Scholar
Modeling HIV-1 integrase complexes based on their hydrodynamic properties.
A. Podtelezhnikov, Kui Gao, F. Bushman, J. McCammon
2003Biopolymers66 citations
Semantic Scholar
Equilibrium distributions of topological states in circular DNA: interplay of supercoiling and knotting.
A. Podtelezhnikov, N. Cozzarelli, Alexander V. Vologodskii
1999Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease
S. Cazanave, A. Podtelezhnikov, K. Jensen, M. Seneshaw +13 more
2017Scientific Reports61 citations Open access
Semantic Scholar
Multimerization-cyclization of DNA fragments as a method of conformational analysis.
A. Podtelezhnikov, Cheng-De Mao, N. Seeman, A. Vologodskii
2000Biophysical Journal49 citations Open access
Semantic Scholar
Simulations of Polymer Cyclization by Brownian Dynamics
A. Podtelezhnikov, A. Vologodskii
199744 citations
Semantic Scholar
Dynamics of small loops in DNA molecules
A. Podtelezhnikov, A. Vologodskii
200039 citations
Semantic Scholar
Bayesian segmental models with multiple sequence alignment profiles for protein secondary structure and contact map prediction
Wei Chu, Zoubin Ghahramani, A. Podtelezhnikov, D. L. Wild
2006IEEE/ACM Transactions on Computational Biology & Bioinformatics35 citations
Semantic Scholar
Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for The Early Assessment of Drug Safety Liabilities.
A. Podtelezhnikov, J. J. Monroe, A. Aslamkhan, Kara M Pearson +6 more
2020Toxicological Sciences34 citations
Semantic Scholar
Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain
Philipp A. Jaeger, Kurt M. Lucin, M. Britschgi, Badri N. Vardarajan +26 more
2016Molecular Neurodegeneration33 citations Open access
Semantic Scholar
Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury
J. J. Monroe, K. Tanis, A. Podtelezhnikov, Truyen Nguyen +14 more
2020Toxicological Sciences29 citations Open access
Semantic Scholar
Understanding the effect of increased cell specific productivity on galactosylation of monoclonal antibodies produced using Chinese hamster ovary cells.
Srinivas Madabhushi, A. Podtelezhnikov, N. Murgolo, Sen Xu +1 more
2021Journal of Biotechnology26 citations
Semantic Scholar
Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline.
Wen Kang, A. Podtelezhnikov, K. Tanis, S. Pacchione +12 more
2020Toxicological Sciences25 citations
Semantic Scholar
Induction of Alzheimer’s‐like changes in brain of mice expressing mutant APP fed excess methionine
Alexander McCampbell, Keith Wessner, M. Marlatt, Carrie Wolffe +9 more
2011Journal of Neurochemistry24 citations Open access
Semantic Scholar
Peculiarities of Structure State and Mechanical Characteristics in Ion-Plasma Condensates of Quasibinary System Borides W2B5-TiB2
O. Sobol', O. N. Grigoryev, Yu. A. Kunitsky, S. Dub +2 more
200623 citations Open access
Semantic Scholar
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies
J. Corton, Constance A. Mitchell, S. Auerbach, P. Bushel +15 more
2022Toxicological Sciences20 citations Open access
Semantic Scholar
AhR Activation in Pharmaceutical Development: Applying Liver Gene Expression Biomarker Thresholds to Identify Doses Associated with Tumorigenic Risks in Rats.
Chunhua Qin, A. Aslamkhan, Kara M Pearson, K. Tanis +6 more
2019Toxicological Sciences19 citations
Semantic Scholar
Source Code for Biology and Medicine Open Access Crankite: a Fast Polypeptide Backbone Conformation Sampler
A. Podtelezhnikov, D. L. Wild, E-mail
19 citations
Semantic Scholar
Toxicogenomics in drug development: a match made in heaven?
Chunhua Qin, K. Tanis, A. Podtelezhnikov, W. Glaab +2 more
2016Expert Opinion on Drug Metabolism & Toxicology18 citations Open access
Semantic Scholar
Transcriptional Profiling of Cholinergic Neurons From Basal Forebrain Identifies Changes in Expression of Genes Between Sleep and Wake
E. Nikonova, Jason Da Gilliland, K. Tanis, A. Podtelezhnikov +7 more
2017Sleep15 citations Open access
Semantic Scholar
Learning about protein hydrogen bonding by minimizing contrastive divergence
A. Podtelezhnikov, Zoubin Ghahramani, D. L. Wild
2006Proteins: Structure, Function, and Bioinformatics14 citations
Semantic Scholar
Reconstruction and stability of secondary structure elements in the context of protein structure prediction.
A. Podtelezhnikov, D. L. Wild
2009Biophysical Journal11 citations Open access
Semantic Scholar
Abstract 26: Notch pathway inhibition with MK-0752 leads to dose- and time-dependent transcriptional alterations in proliferation, PI3K, andWntpathway genes in plucked human hair follicles
S. Blackman, A. Podtelezhnikov, R. Railkar, A. Loboda +6 more
20106 citations
Semantic Scholar
Abstract B41: Identification of a time‐ and dose‐responsive transcriptional signature of Notch pathway inhibition in plucked human hair follicles following exposure to the gamma‐secretase inhibitor MK‐0752
S. Blackman, J. Klappenbach, R. Railkar, K. Tanis +9 more
20095 citations
Semantic Scholar
A mechanistic biomarker investigation of fialuridine hepatotoxicity using the chimeric TK-NOG Hu-liver mouse model and in vitro micropatterned hepatocyte cocultures.
A. Aslamkhan, L. Michna, A. Podtelezhnikov, K. Vlasakova +17 more
2024Toxicological Research4 citations
Semantic Scholar
Alterations in choroid plexus gene expression in Alzheimer’s disease provide inferences for CSF composition and dynamics
Miles C. Miller, E. Stopa, E. Nikonova, K. Tanis +13 more
2010Cerebrospinal Fluid Research3 citations Open access
Semantic Scholar
Inferring Knowledge Based Potentials Using Contrastive Divergence
A. Podtelezhnikov, D. L. Wild
20122 citations
Semantic Scholar
Qualification and application of an in vitro liver model early in pharmaceutical development to help derisk drug-induced liver injury (DILI)
K. Mitra, Wenling Kang, K. Tanis, S. Pacchione +14 more
2019Drug Metabolism and Pharmacokinetics1 citations
Semantic Scholar
Transcriptomic biomarkers to assess the liver and metabolic responses associated with bioactivation mechanisms of drug induced liver injury
J. J. Monroe, K. Tanis, A. Podtelezhnikov, Truyen Nguyen +17 more
2019Drug Metabolism and Pharmacokinetics1 citations
Semantic Scholar
Comparative transcriptomics of choroid plexus in Alzheimer’s disease, frontotemporal dementia and Huntington’s disease: implications for CSF homeostasis
E. Stopa, K. Tanis, Miles C. Miller, E. Nikonova +12 more
2018Fluids and Barriers of the CNS1 citations Open access
Semantic Scholar
Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain
Philipp A. Jaeger, Kurt M. Lucin, M. Britschgi, Badri N. Vardarajan +26 more
2016Molecular Neurodegeneration1 citations Open access
Semantic Scholar
Comment on "Efficient Monte Carlo trial moves for polypeptide simulations" [J. Chem. Phys. 123, 174905 (2005)].
A. Podtelezhnikov, D. L. Wild
2008Journal of Chemical Physics1 citations Open access
Semantic Scholar
Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease
S. Cazanave, A. Podtelezhnikov, K. Jensen, M. Seneshaw +13 more
2020Scientific Reports0 citations Open access
Semantic Scholar
Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease
S. Cazanave, A. Podtelezhnikov, K. Jensen, M. Seneshaw +13 more
2020Scientific Reports0 citations Open access
Semantic Scholar
The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease
S. Cazanave, A. Podtelezhnikov, K. Jensen, M. Seneshaw +13 more
2017Scientific Reports0 citations Open access
Semantic Scholar
FEATURES OF STRENGTHENING OF NANO- AND SUBMICROCRYSTALLINE Al-Fe CONDENSATES
E. Lutsenko, O. Sobol, A. Podtelezhnikov, A. Zubkov
2016eNTUKhPIIR Repository (Kharkiv Polytechnic Institute)0 citations Open access
Semantic Scholar
Gene expression profiling of cholinergic neurons from basal forebrain help identify novel sleep-wake regulating pathways
Ev Nikovna, J. Gilliland, K. Tanis, A. Podtelezhnikov +7 more
20150 citations
Semantic Scholar
REDUCED CIRCADIAN RHYTHMICITY IN INDIVIDUALS RESISTANT TO SLEEP DEPRIVATION Blood-Gene Expression Reveals Reduced Circadian Rhythmicity in Individuals Resistant to Sleep Deprivation
E. Arnardóttir, E. Nikonova, K. Shockley, A. Podtelezhnikov +6 more
20140 citations
Semantic Scholar
P1‐120: High methionine diet induces beta‐amyloid–related transcriptional changes in mouse brain
Alexander McCampbell, Keith Wessner, Dawn M. Toolan, A. Podtelezhnikov +4 more
20100 citations Open access
Semantic Scholar
Baysian Segmental Models for Protein Secondary Structure and Contact Map Prediction
Wei Chu, Zoubin Ghahramani, A. Podtelezhnikov, D. L. Wild
20060 citations
Semantic Scholar
Study of microdeformation and creep of an aluminum-magnesium alloy at low stresses and temperatures
A. Podtelezhnikov, V. V. Demirskiĭ
19950 citations
Semantic Scholar

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