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Sam Walcott · SciRah

Researcher profile · Semantic Scholar

Sam Walcott

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Sam Walcott — researcher profile on SciRah

h-index: 19
Works: 59
Citations: 1,458

Most-cited papers

A mechanical model of actin stress fiber formation and substrate elasticity sensing in adherent cells
Sam Walcott, Sean X. Sun
2010Proceedings of the National Academy of Sciences of the United States of America244 citations Open access
Semantic Scholar
Actin cap associated focal adhesions and their distinct role in cellular mechanosensing
Dong-hwee Kim, Shyam B. Khatau, Yun-Feng Feng, Sam Walcott +3 more
2012Scientific Reports208 citations Open access
Semantic Scholar
Supplementary Information For “ Mechanical coupling between myosin molecules causes differences between ensemble and single molecule measurements ”
Sam Walcott, D. Warshaw, E. Debold
2012112 citations
Semantic Scholar
Adhesion Dynamics and Durotaxis in Migrating Cells
Ben Harland, Sam Walcott, Sean X. Sun
2011Physical Biology98 citations Open access
Semantic Scholar
Cytoskeletal Cross-linking and Bundling in Motor-Independent Contraction
Sean X. Sun, Sam Walcott, C. Wolgemuth
2010Current Biology96 citations Open access
Semantic Scholar
Direct observation of phosphate inhibiting the force-generating capacity of a miniensemble of Myosin molecules.
E. Debold, Sam Walcott, Mike K. Woodward, Matthew A. Turner
2013Biophysical Journal74 citations Open access
Semantic Scholar
Binding site models of friction due to the formation and rupture of bonds: state-function formalism, force-velocity relations, response to slip velocity transients, and slip stability.
M. Srinivasan, Sam Walcott
2009Physical review. E, Statistical, nonlinear, and soft matter physics55 citations
Semantic Scholar
Phosphate enhances myosin-powered actin filament velocity under acidic conditions in a motility assay.
E. Debold, Matthew A. Turner, Jordan C. Stout, Sam Walcott
2011American Journal of Physiology. Regulatory Integrative and Comparative Physiology54 citations
Semantic Scholar
Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro
A. Lombardo, Shane R. Nelson, M. Y. Ali, G. Kennedy +3 more
2017Nature Communications44 citations Open access
Semantic Scholar
Modeling residual force enhancement with generic cross-bridge models.
Sam Walcott, W. Herzog
2008Mathematical Biosciences44 citations
Semantic Scholar
Nucleation and decay initiation are the stiffness-sensitive phases of focal adhesion maturation.
Sam Walcott, Dong-hwee Kim, D. Wirtz, Sean X. Sun
2011Biophysical Journal43 citations Open access
Semantic Scholar
Effects of cardiac Myosin binding protein-C on actin motility are explained with a drag-activation-competition model.
Sam Walcott, S. Docken, S. Harris
2015Biophysical Journal39 citations Open access
Semantic Scholar
The load dependence of rate constants.
Sam Walcott
2008Journal of Chemical Physics37 citations
Semantic Scholar
Hysteresis in cross-bridge models of muscle.
Sam Walcott, Sean X. Sun
2009Physical Chemistry, Chemical Physics - PCCP36 citations Open access
Semantic Scholar
Acidosis affects muscle contraction by slowing the rates myosin attaches to and detaches from actin
K. Jarvis, Mike K. Woodward, E. Debold, Sam Walcott
2018Journal of Muscle Research and Cell Motility34 citations
Semantic Scholar
Smooth Muscle Heavy Meromyosin Phosphorylated on One of Its Two Heads Supports Force and Motion*
Sam Walcott, P. Fagnant, K. Trybus, D. Warshaw
2009Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Mechanosensitive Adhesion Explains Stepping Motility in Amoeboid Cells.
C. Copos, Sam Walcott, J. D. del Álamo, Effie E. Bastounis +2 more
2017Biophysical Journal30 citations Open access
Semantic Scholar
The molecular basis of thin filament activation: from single molecule to muscle
Thomas J. Longyear, Sam Walcott, E. Debold
2017Scientific Reports29 citations Open access
Semantic Scholar
Myosin Va transport of liposomes in three-dimensional actin networks is modulated by actin filament density, position, and polarity
A. Lombardo, Shane R. Nelson, G. Kennedy, K. Trybus +2 more
2019Proceedings of the National Academy of Sciences of the United States of America28 citations Open access
Semantic Scholar
Force-velocity and tension transient measurements from Drosophila jump muscle reveal the necessity of both weakly-bound cross-bridges and series elasticity in models of muscle contraction
K. Jarvis, K. Bell, Amy K. Loya, D. Swank +1 more
2021Archives of Biochemistry and Biophysics18 citations Open access
Semantic Scholar
Muscle activation described with a differential equation model for large ensembles of locally coupled molecular motors.
Sam Walcott
2014Physical review. E, Statistical, nonlinear, and soft matter physics18 citations
Semantic Scholar
Active force generation in cross-linked filament bundles without motor proteins.
Sam Walcott, Sean X. Sun
2010Physical review. E, Statistical, nonlinear, and soft matter physics17 citations
Semantic Scholar
Enzyme kinetics of muscle glycogen phosphorylase b.
Sam Walcott, S. Lehman
2007Biochemistry15 citations
Semantic Scholar
Modeling smooth muscle myosin's two heads: long-lived enzymatic roles and phosphorylation-dependent equilibria.
Sam Walcott, D. Warshaw
2010Biophysical Journal11 citations Open access
Semantic Scholar
Modeling Thick Filament Activation Suggests a Molecular Basis for Force Depression
Shuyue Liu, Christopher P. Marang, Mike K. Woodward, V. Joumaa +5 more
2023bioRxiv10 citations Open access
Semantic Scholar
Direct Measurements of Local Coupling between Myosin Molecules Are Consistent with a Model of Muscle Activation
Sam Walcott, N. Kad
2015PLoS Comput. Biol.10 citations Open access
Semantic Scholar
The load dependence of muscle's force-velocity curve is modulated by alternative myosin converter domains.
Christopher S. Newhard, Sam Walcott, D. Swank
2019American Journal of Physiology - Cell Physiology8 citations Open access
Semantic Scholar
In defense of Huxley.
Sam Walcott, Sean X. Sun, E. Debold, Walter Herzog
2024Biophysical Journal6 citations Open access
Semantic Scholar
A Differential Equation Model for Tropomyosin-induced Myosin Cooperativity Describes Myosin–Myosin Interactions at Low Calcium
Sam Walcott
20136 citations Open access
Semantic Scholar
Actin crosslinkers: repairing the sense of touch.
Sean X. Sun, Sam Walcott
2010Current Biology2 citations Open access
Semantic Scholar
In Silico Model of Myosin VA-Mediated Liposome Transport Predicts Actin Filament Density and Liposome Diameter Dictate Transport Modes
Sam Walcott, D. Warshaw
20201 citations Open access
Semantic Scholar
Spatial relations matter: Kinesin-1-based liposome transport through 3D microtubule intersections in vitro and in silico
Brandon M. Bensel, S. Previs, Carol S. Bookwalter, K. Trybus +2 more
2024Biophysical Journal0 citations
Semantic Scholar
A branched-pathway model for phosphate explains load-dependent interactions of mini-myosin ensembles with actin
Daniel J. Petersen, Christopher P. Marang, E. Debold, Sam Walcott
2024Biophysical Journal0 citations
Semantic Scholar
Fitting a model to multiscale data suggests thick filament activation can produce force depression in muscle fibers.
Sam Walcott, Shuyue Liu, Christopher P. Marang, Mike K. Woodward +5 more
2023Biophysical Journal0 citations Open access
Semantic Scholar
Kinesin vesicular transport through 2D and 3D microtubule intersections.
Brandon M. Bensel, S. Previs, Carol S. Bookwalter, Sam Walcott +2 more
2023Biophysical Journal0 citations Open access
Semantic Scholar
Stretch-Activation in Drosophila Jump Muscle Fibers is Described by a Minimal Cross-Bridge Model that Includes Force-Dependent Weakly-Bound Cross-Bridges and Series Elasticity
K. Jarvis, K. Bell, Amy K. Loya, D. Swank +1 more
20210 citations Open access
Semantic Scholar
Weakly-Bound, Non-Linear Elastic Cross-Bridges are Required to Self-Consistently Model the FENN Effect, Force Velocity and Tension Transients in Muscle Fibers
K. Jarvis, K. Bell, Amy K. Loya, D. Swank +1 more
20200 citations Open access
Semantic Scholar
Muscle Measurements Show Weakly Bound Cross-Bridges Act as a Viscous Drag
Sam Walcott, K. Jarvis
2019Biophysical Journal0 citations Open access
Semantic Scholar
Local Actin Filament Geometry Dictates How Myosin Va Molecular Motor Teams Transport Liposomes Through 3D Actin Networks in Vitro
Sam Walcott, A. Lombardo, K. Trybus, D. Warshaw
2019Biophysical Journal0 citations Open access
Semantic Scholar
A Minimal Model for the Effects of pH and Phosphate on Muscle Provides a Molecular Basis for Cellular Measurements
K. Jarvis, E. Debold, Sam Walcott, Mike K. Woodward
20180 citations Open access
Semantic Scholar
Myosin Va Vesicular Transport is Modulated by Actin Filament Density, Orientation, and Polarity in an In Vitro 3D Actin Network
A. Lombardo, Shane R. Nelson, G. Kennedy, K. Trybus +2 more
20180 citations Open access
Semantic Scholar
Effect of Calcium on Myosin Binding to a Regulated Thin Filament from Single Molecule to Ensemble
Thomas J. Longyear, Sam Walcott, E. Debold
20170 citations Open access
Semantic Scholar
Myosin Va Motor Teams Navigate Vesicle Cargos through 3D Actin Filament Intersections
A. Lombardo, Shane R. Nelson, M. Y. Ali, K. Trybus +2 more
20160 citations Open access
Semantic Scholar
Using Single Myosin and Small Myosin Ensembles to Examine Thin Filament Activation in a Laser Trap Assay
Thomas J. Longyear, Matt Unger, Ling Xin, Sam Walcott +1 more
20160 citations Open access
Semantic Scholar
3D Model of Vesicles Transported by Myosin Va Motor Teams through Actin Intersections Predicts Experimental Directional Outcomes
Sam Walcott, A. Lombardo, Shane R. Nelson, M. Y. Ali +1 more
20160 citations Open access
Semantic Scholar
Observing the pCa-Force Relationship with a 3-Bead Laser Trap Assay
Thomas J. Longyear, Sam Walcott, E. Debold
20150 citations Open access
Semantic Scholar
Adding Regulation to Cross-Bridge Muscle Models
Sam Walcott
20140 citations Open access
Semantic Scholar
Motor-motor interactions in ensembles of muscle myosin: using theory to connect single molecule to ensemble measurements
Sam Walcott
20130 citations
Semantic Scholar
Progress towards an accurate molecular muscle model.
Sam Walcott
20130 citations
Semantic Scholar
Myosin-Induced Detachment Causes Differences Between Ensemble and Single Molecule Myosin Kinetics
Sam Walcott, E. Debold
20120 citations Open access
Semantic Scholar

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