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Marcos Malumbres · SciRah

Researcher profile · Semantic Scholar

Marcos Malumbres

Vall d'Hebron Institute of Oncology (VHIO)
ICREA Professor

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Marcos Malumbres — researcher profile on SciRah

ORCID iD 0000-0002-0829-6315Homepage

h-index: 75
Works: 254
Citations: 29K

Most-cited papers

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases
P. Hydbring, Marcos Malumbres, P. Sicinski
2016Nature reviews. Molecular cell biology487 citations Open access
Semantic Scholar
Mechanisms of Sensitivity and Resistance to CDK4/6 Inhibition.
Mónica Álvarez-Fernández, Marcos Malumbres
2020Cancer Cell342 citations Open access
Semantic Scholar
The cell proliferation antigen Ki-67 organises heterochromatin
M. Sobecki, K. Mrouj, A. Camasses, N. Parisis +17 more
2016eLife334 citations Open access
Semantic Scholar
Programmed mitophagy is essential for the glycolytic switch during cell differentiation
L. Esteban-Martínez, Elena Sierra-Filardi, R. Mcgreal, María Salazar-Roa +10 more
2017EMBO Journal316 citations Open access
Semantic Scholar
Fueling the Cell Division Cycle.
María Salazar-Roa, Marcos Malumbres
2017Trends in Cell Biology255 citations
Semantic Scholar
CDK6 as a key regulator of hematopoietic and leukemic stem cell activation.
Ruth Scheicher, Andrea Hoelbl-Kovacic, F. Bellutti, Anca-Sarmiza Tigan +9 more
2015Blood237 citations Open access
Semantic Scholar
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy
Ruth Sánchez-Martínez, Silvia Cruz-Gil, M. G. de Cedrón, Mónica Álvarez-Fernández +10 more
2015OncoTarget151 citations Open access
Semantic Scholar
CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma.
Beatriz Salvador-Barberó, Mónica Álvarez-Fernández, Elisabet Zapatero-Solana, Aicha El Bakkali +8 more
2020Cancer Cell147 citations Open access
Semantic Scholar
Plk1 overexpression induces chromosomal instability and suppresses tumor development
G. de Cárcer, S. Venkateswaran, L. Salgueiro, Aicha El Bakkali +9 more
2018Nature Communications145 citations Open access
Semantic Scholar
Mammalian cell cycle cyclins.
Diego Martínez-Alonso, Marcos Malumbres
2020Seminars in Cell and Developmental Biology140 citations
Semantic Scholar
Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development
A. González-Loyola, Gonzalo Fernández-Miranda, M. Trakala, David Partida +9 more
2015Molecular and Cellular Biology112 citations Open access
Semantic Scholar
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis
Helena Serra, I. Chivite, Ana Angulo-Urarte, Adriana Soler +16 more
2015Nature Communications104 citations Open access
Semantic Scholar
p38γ is essential for cell cycle progression and liver tumorigenesis
Antonia Tomás-Loba, E. Manieri, Bárbara González-Terán, A. Mora +29 more
2019Nature94 citations Open access
Semantic Scholar
Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer
Mónica Álvarez-Fernández, María Sanz-Flores, Belén Sanz-Castillo, María Salazar-Roa +10 more
2017Cell Death and Differentiation85 citations Open access
Semantic Scholar
Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells
S. Rata, Maria F. Suarez Peredo Rodriguez, Stephy Joseph, Nisha Peter +11 more
2018Current Biology78 citations Open access
Semantic Scholar
CDK6 antagonizes p53-induced responses during tumorigenesis
F. Bellutti, Anca-Sarmiza Tigan, S. Nebenfuehr, M. Dolezal +23 more
2018Cancer Discovery68 citations Open access
Semantic Scholar
Genetic interactions between the Aurora kinases reveal new requirements for AURKB and AURKC during oocyte meiosis
Alexandra L. Nguyen, Dávid Drutovič, B. Vazquez, W. El Yakoubi +4 more
2018Current Biology67 citations Open access
Semantic Scholar
A Cdh1-APC/FMRP Ubiquitin Signaling Link Drives mGluR-Dependent Synaptic Plasticity in the Mammalian Brain
Ju Huang, Y. Ikeuchi, Marcos Malumbres, A. Bonni
2015Neuron62 citations Open access
Semantic Scholar
An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability
J. Mitxelena, A. Apraiz, Jon Vallejo-Rodríguez, I. García-Santisteban +4 more
2018Nucleic Acids Research58 citations Open access
Semantic Scholar
Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis
G. de Cárcer, Paulina Wachowicz, S. Martínez-Martínez, J. Oller +14 more
2017Nature Medicine58 citations Open access
Semantic Scholar
Functional reprogramming of polyploidization in megakaryocytes.
M. Trakala, Sara Rodríguez-Acebes, M. Maroto, C. Symonds +5 more
2015Developmental Cell54 citations Open access
Semantic Scholar
Aurora A drives early signalling and vesicle dynamics during T-cell activation
Noelia Blas‐Rus, E. Bustos‐Morán, I. Pérez de Castro, G. de Cárcer +8 more
2016Nature Communications45 citations Open access
Semantic Scholar
Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner
Jia Liu, L. Wan, Jing Liu, Zhu Yuan +6 more
2016Cell Discovery43 citations Open access
Semantic Scholar
Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma
P. López-Nieva, P. Fernández-Navarro, O. Graña-Castro, Eduardo Andrés-León +7 more
2019Scientific Reports40 citations Open access
Semantic Scholar
Effects of energy metabolism on the mechanical properties of breast cancer cells
Marina. L. Yubero, P. Kosaka, Álvaro San Paulo, Marcos Malumbres +2 more
2020Communications Biology38 citations Open access
Semantic Scholar
A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis
K. Kollmann, G. Heller, Christine Schneckenleithner, W. Warsch +20 more
2016Cancer Cell38 citations Open access
Semantic Scholar
USP7 limits CDK1 activity throughout the cell cycle
Antonio Galarreta, P. Valledor, Patricia Ubieto-Capella, V. Lafarga +5 more
2021EMBO Journal35 citations Open access
Semantic Scholar
A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells
Teresa Olbrich, Maria Vega-Sendino, M. Murga, G. de Cárcer +4 more
2019Cell Reports32 citations Open access
Semantic Scholar
E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation
J. Mitxelena, A. Apraiz, Jon Vallejo-Rodríguez, Marcos Malumbres +1 more
2016Nucleic Acids Research31 citations Open access
Semantic Scholar
The MASTL/PP2A cell cycle kinase‐phosphatase module restrains PI3K‐Akt activity in an mTORC1‐dependent manner
Belén Sanz-Castillo, B. Hurtado, Diana Vara-Ciruelos, Aicha El Bakkali +10 more
2022EMBO Journal30 citations Open access
Semantic Scholar
Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets
B. Hurtado, M. Trakala, P. Ximénez-Embún, Aicha El Bakkali +9 more
2018Journal of Clinical Investigation30 citations Open access
Semantic Scholar
PLK1 regulates centrosome migration and spindle dynamics in male mouse meiosis
E. Alfaro, P. López-Jiménez, J. González-Martínez, Marcos Malumbres +2 more
2021EMBO Reports29 citations Open access
Semantic Scholar
microRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemia
Nadia C. Correia, A. Melão, Vanda Póvoa, L. Sarmento +4 more
2016OncoTarget29 citations Open access
Semantic Scholar
CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma.
Beatriz Salvador-Barberó, Mónica Álvarez-Fernández, Elisabet Zapatero-Solana, Aicha El Bakkali +8 more
2020Cancer Cell28 citations Open access
Semantic Scholar
The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites
Kyungsoo Ha, Chengxia Ma, Han Lin, Lichun Tang +12 more
2017Nature Communications27 citations Open access
Semantic Scholar
Squamous differentiation requires G2/mitosis slippage to avoid apoptosis
Natalia Sanz-Gómez, I. D. de Pedro, Beatriz Ortigosa, David Santamaría +3 more
2020Cell Death and Differentiation26 citations Open access
Semantic Scholar
An essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stress
V. Quereda, E. Porlan, M. Cañamero, P. Dubus +1 more
2015Cell Death and Differentiation26 citations Open access
Semantic Scholar
Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
Brittiny Dhital, S. Santasusagna, P. Kirthika, Michael Xu +17 more
2023Cell Reports Medicine25 citations Open access
Semantic Scholar
Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid
Rui Shao, Jia Liu, Guang Yan, Jinfang Zhang +9 more
2016Cell Research23 citations Open access
Semantic Scholar
Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice.
M. Trakala, David Partida, María Salazar-Roa, M. Maroto +3 more
2015Blood23 citations Open access
Semantic Scholar
CDK4/6 Inhibitors: What Is the Best Cocktail?
Marcos Malumbres
2018Clinical Cancer Research20 citations
Semantic Scholar
Transient exposure to miR‐203 enhances the differentiation capacity of established pluripotent stem cells
María Salazar-Roa, M. Trakala, Mónica Álvarez-Fernández, F. Valdés-Mora +18 more
2020EMBO Journal17 citations Open access
Semantic Scholar
SnapShot: Phosphoregulation of Mitosis.
A. Burgess, Jenny Vuong, Samuel Rogers, Marcos Malumbres +1 more
2017Cell17 citations Open access
Semantic Scholar
E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation.
J. Mitxelena, A. Apraiz, Jon Vallejo-Rodríguez, Marcos Malumbres +1 more
2016Nucleic Acids Research16 citations Open access
Semantic Scholar
miR-203 drives breast cancer cell differentiation
Nuria G. Martínez-Illescas, S. Leal, Patricia González, O. Graña-Castro +17 more
2023bioRxiv15 citations Open access
Semantic Scholar
Deregulated expression of Cdc6 in the skin facilitates papilloma formation and affects the hair growth cycle
S. Búa, P. Sotiropoulou, C. Sgarlata, L. Borlado +6 more
2015Cell Cycle15 citations Open access
Semantic Scholar
Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility
Carolina Villarroya-Beltri, Ana Osorio, R. Torres-Ruíz, D. Gómez-Sánchez +12 more
2022Science Advances14 citations Open access
Semantic Scholar
Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias
J. González-Martínez, A. Cwetsch, Diego Martínez-Alonso, Luis R. López-Sainz +12 more
2021JCI Insight14 citations Open access
Semantic Scholar
Phosphoproteomic analysis of neoadjuvant breast cancer suggests that increased sensitivity to paclitaxel is driven by CDK4 and filamin A
S. Mourón, M. J. Bueno, A. Lluch, L. Manso +23 more
2022Nature Communications13 citations Open access
Semantic Scholar
Haspin participates in AURKB recruitment to centromeres and contributes to chromosome congression in male mouse meiosis.
Berenguer I, P. López-Jiménez, I. Mena, A. Viera +6 more
2022Journal of Cell Science13 citations Open access
Semantic Scholar

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