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G. Goel · SciRah

Researcher profile · Semantic Scholar

G. Goel

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G. Goel — researcher profile on SciRah

h-index: 33
Works: 67
Citations: 8,073

Most-cited papers

Succinate is a danger signal that induces IL-1β via HIF-1α
G. Tannahill, Anne M. Curtis, Juraj Adamik, E. Pålsson-McDermott +28 more
2013Nature3,704 citations Open access
Semantic Scholar
Pyruvate Kinase M2 regulates Hif-1α activity and IL-1β induction, and is a critical determinant of the Warburg Effect in LPS-activated macrophages
E. Pålsson-McDermott, Anne M. Curtis, G. Goel, M. Lauterbach +14 more
2015Cell Metabolism999 citations Open access
Semantic Scholar
Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.
E. Pålsson-McDermott, Anne M. Curtis, G. Goel, M. Lauterbach +14 more
2015Cell Metabolism622 citations Open access
Semantic Scholar
Non-degradative Role of Atg5-Atg12/Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon gamma
Seungmin Hwang, N. Maloney, Monique W. Bruinsma, G. Goel +11 more
2012Cell Host and Microbe248 citations Open access
Semantic Scholar
Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection
K. Conway, Petric Kuballa, J. Song, Khushbu K. Patel +19 more
2013Gastroenterology241 citations Open access
Semantic Scholar
Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis
M. Beaudoin, P. Goyette, G. Boucher, Ken-Sin Lo +30 more
2013PLoS Genetics214 citations Open access
Semantic Scholar
Mechanisms of Pediatric Inflammatory Bowel Disease.
Joanna M. Peloquin, G. Goel, E. Villablanca, R. Xavier
2016Annual Review of Immunology138 citations
Semantic Scholar
Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk
K. Lassen, C. McKenzie, M. Mari, T. Murano +13 more
2016Immunity129 citations Open access
Semantic Scholar
Epitope-specific immunotherapy targeting CD4+ T cells in celiac disease: evaluation in randomized, double-blind, placebo-controlled phase 1 studies
G. Goel, T. King, A. J. Daveson, J. Andrews +24 more
2017The Lancet Gastroenterology and Hepatology127 citations Open access
Semantic Scholar
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease
G. Goel, J. Tye-Din, Shuo-Wang Qiao, A. Russell +12 more
2019Science Advances125 citations Open access
Semantic Scholar
RNF166 Determines Recruitment of Adaptor Proteins During Antibacterial Autophagy
Robert J. W. Heath, G. Goel, Leigh A. Baxt, J. Rush +5 more
2016Cell Reports103 citations Open access
Semantic Scholar
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells
B. Khor, John D. Gagnon, G. Goel, M. Roche +19 more
2015eLife96 citations Open access
Semantic Scholar
Concomitant BRAF and PI3K/mTOR Blockade is Required for Effective Treatment of BRAFV600E Colorectal Cancer
Erin M. Coffee, A. Faber, Jatin Roper, M. Sinnamon +12 more
2013Clinical Cancer Research85 citations Open access
Semantic Scholar
Elevated serum interleukin‐2 after gluten correlates with symptoms and is a potential diagnostic biomarker for coeliac disease
J. Tye-Din, A. James M. Daveson, H. Ee, G. Goel +7 more
2019Alimentary Pharmacology and Therapeutics75 citations Open access
Semantic Scholar
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics
Szu-Yu Kuo, A. Castoreno, L. Aldrich, K. Lassen +12 more
2015Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Essential Cell-Autonomous Role for Interferon (IFN) Regulatory Factor 1 in IFN-γ-Mediated Inhibition of Norovirus Replication in Macrophages
N. Maloney, Larissa B. Thackray, G. Goel, Seungmin Hwang +4 more
2012Journal of Virology65 citations Open access
Semantic Scholar
Serum cytokines elevated during gluten‐mediated cytokine release in coeliac disease
G. Goel, A. J. Daveson, C. E. Hooi, J. Tye-Din +7 more
2020Clinical and Experimental Immunology62 citations Open access
Semantic Scholar
Selective modulation of autophagy, innate immunity and adaptive immunity by small molecules
S. Shaw, K. Tran, A. Castoreno, Joanna M. Peloquin +11 more
2013ACS Chemical Biology62 citations Open access
Semantic Scholar
Succinate is a danger signal that induces IL-1β via HIF-1α
G. Tannahill, Amanda Curtis, J. Adamík, EM Palsson-McDermott +30 more
201461 citations
Semantic Scholar
Profiling DNA damage-induced phosphorylation in budding yeast reveals diverse signaling networks
Chun-Shui Zhou, A. Elia, Maria L. Naylor, Noah E. Dephoure +8 more
2016Proceedings of the National Academy of Sciences of the United States of America58 citations Open access
Semantic Scholar
Integrated genomics of Crohn’s disease risk variant identifies a role for CLEC12A in antibacterial autophagy
J. Begun, K. Lassen, H. Jijon, Leigh A. Baxt +18 more
2015Cell Reports52 citations Open access
Semantic Scholar
A systems biology viewpoint on autophagy in health and disease
A. Huett, G. Goel, R. Xavier
2010Current Opinion in Gastroenterology50 citations Open access
Semantic Scholar
p40phox Expression Regulates Neutrophil Recruitment and Function During the Resolution Phase of Intestinal Inflammation
K. Conway, G. Goel, H. Sokol, M. Manocha +5 more
2012Journal of Immunology48 citations Open access
Semantic Scholar
Randomised clinical trial: a placebo‐controlled study of subcutaneous or intradermal NEXVAX2, an investigational immunomodulatory peptide therapy for coeliac disease
K. Truitt, A. James M. Daveson, H. Ee, G. Goel +3 more
2019Alimentary Pharmacology and Therapeutics47 citations
Semantic Scholar
Masked bolus gluten challenge low in FODMAPs implicates nausea and vomiting as key symptoms associated with immune activation in treated coeliac disease
A. James M. Daveson, J. Tye-Din, G. Goel, K. E. Goldstein +5 more
2019Alimentary Pharmacology and Therapeutics47 citations Open access
Semantic Scholar
Nitric Oxide Engages an Anti-inflammatory Feedback Loop Mediated by Peroxiredoxin 5 in Phagocytes
D. Graham, Guadalupe J. Jasso, A. Mok, G. Goel +8 more
2018Cell Reports47 citations Open access
Semantic Scholar
Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity
J. Tye-Din, G. Skodje, V. Sarna, J. Dzuris +8 more
2020United European Gastroenterology journal46 citations Open access
Semantic Scholar
Characterization of candidate genes in inflammatory bowel disease–associated risk loci
Joanna M. Peloquin, G. Goel, Ling-Jia Kong, Hai-Liang Huang +8 more
2016JCI Insight46 citations Open access
Semantic Scholar
Discovery of a Small-Molecule Probe for V-ATPase Function
L. Aldrich, Szu-Yu Kuo, A. Castoreno, G. Goel +8 more
2015Journal of the American Chemical Society43 citations Open access
Semantic Scholar
Whole blood interleukin‐2 release test to detect and characterize rare circulating gluten‐specific T cell responses in coeliac disease
R. P. Anderson, G. Goel, M. Hardy, K. A +9 more
2021Clinical and Experimental Immunology40 citations Open access
Semantic Scholar
Patient factors influencing acute gluten reactions and cytokine release in treated coeliac disease
J. Tye-Din, A. James M. Daveson, K. E. Goldstein, H. Hand +5 more
2020BMC Medicine39 citations Open access
Semantic Scholar
Systems Immunology Reveals Markers of Susceptibility to West Nile Virus Infection
Feng Qian, G. Goel, Hailong Meng, Xiao-Mei Wang +13 more
2014Clinical and Vaccine Immunology39 citations Open access
Semantic Scholar
Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst
D. Graham, Christine E. Becker, Aivi Doan, G. Goel +8 more
2015Nature Communications35 citations Open access
Semantic Scholar
Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation Citation
E. Martin, Peter J. Belmont, M. Sinnamon, L. Richard +18 more
201432 citations
Semantic Scholar
A Sensitive Whole Blood Assay Detects Antigen-Stimulated Cytokine Release From CD4+ T Cells and Facilitates Immunomonitoring in a Phase 2 Clinical Trial of Nexvax2 in Coeliac Disease
M. Hardy, G. Goel, A. Russell, S. Chen Yi Mei +11 more
2021Frontiers in Immunology28 citations Open access
Semantic Scholar
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling
M. Bambouskova, Iva Polakovičová, I. Halova, G. Goel +7 more
2016Molecular and Cellular Biology28 citations Open access
Semantic Scholar
Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study.
J. Tye-Din, A. J. Daveson, G. Goel, K. E. Goldstein +9 more
2023The Lancet Gastroenterology and Hepatology27 citations Open access
Semantic Scholar
Drug Misuse in Adolescents Presenting to the Emergency Department
Y. Finkelstein, G. Goel, J. Hutson, J. Armstrong +3 more
2017Pediatric emergency care23 citations
Semantic Scholar
Latent Gammaherpesvirus 68 Infection Induces Distinct Transcriptional Changes in Different Organs
S. Canny, G. Goel, Tiffany A. Reese, Xin Zhang +2 more
2013Journal of Virology21 citations Open access
Semantic Scholar
Can improved glycemic control slow renal function decline at all stages of diabetic nephropathy?
G. Goel, B. Perkins
2012Seminars in Nephrology10 citations
Semantic Scholar
Multivariate inference of pathway activity in host immunity and response to therapeutics
G. Goel, K. Conway, M. Jaeger, M. Netea +1 more
2014Nucleic Acids Research9 citations Open access
Semantic Scholar
An Image-Based Genetic Assay Identifies Genes in T1D Susceptibility Loci Controlling Cellular Antiviral Immunity in Mouse
J. Liao, H. Jijon, I. Kim, G. Goel +6 more
2014PLoS ONE8 citations Open access
Semantic Scholar
Does long term colchicine prevent degradation of collagen fiber network in osteoarthritis?
R. Srivastava, S. Das, G. Goel, Akash Asthana +1 more
2017International Journal of Rheumatic Diseases7 citations
Semantic Scholar
Heterogeneity in Comparisons of Discontinuation of Tumor Necrosis Factor Antagonists in Rheumatoid Arthritis - A Meta-Analysis
Anat Fisher, K. Bassett, G. Goel, Dana Stanely +4 more
2016PLoS ONE6 citations Open access
Semantic Scholar
O-002 Genes in IBD-Associated Risk Loci Demonstrate Genotype-, Tissue-, and Inflammation-Specific Patterns of Expression in Terminal Ileum and Colon Mucosal Tissue
Joanna M. Peloquin, G. Goel, Hai-Liang Huang, T. Haritunians +6 more
2016Inflammatory Bowel Diseases4 citations Open access
Semantic Scholar
Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation
Eric Martin, Peter J. Belmont, M. Sinnamon, L. Richard +19 more
2013Clinical Cancer Research4 citations Open access
Semantic Scholar
O-015 YI Alterations in the FOXP3-EZH2 Pathway Associates with Increased Susceptibility to Colitis in Both Mice and Human
Olga F. Sarmento, Yu-Ning Xiong, Zhi-Fu Sun, P. Svingen +11 more
2016Inflammatory Bowel Diseases3 citations Open access
Semantic Scholar
Sa1396 A Single Intradermal (ID) Injection of Nexvax2®, a Peptide Composition With Dominant Epitopes for Gluten-Reactive CD4+ T Cells, Activates T Cells and Triggers Acute Gastrointestinal Symptoms in HLA-DQ2.5+ People With Celiac Disease (CeD)
G. Goel, Toufic Mayassi, Shuo-Wang Qiao, C. Ciszewski +20 more
20163 citations
Semantic Scholar
P023 Fatigue in quiescent inflammatory bowel disease is associated with low GM-CSF levels and metabolomic alterations.
N. Borren, G. Goel, K. Lassen, K. Devaney +6 more
2017Journal of Crohn's & Colitis2 citations Open access
Semantic Scholar
Fatigue in Quiescent Inflammatory Bowel Disease is Associated with Low GM-CSF Levels and Metabolomic Alterations
N. Borren, G. Goel, K. Lassen, K. Devaney +6 more
20172 citations
Semantic Scholar

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