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C. Koehler · SciRah

Researcher profile · Semantic Scholar

C. Koehler

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C. Koehler — researcher profile on SciRah

h-index: 51
Works: 128
Citations: 10K

Most-cited papers

Importing Mitochondrial Proteins: Machineries and Mechanisms
A. Chacińska, C. Koehler, Dusanka Milenkovic, T. Lithgow +1 more
2009Cell1,439 citations Open access
Semantic Scholar
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells
Jin Zhang, I. Khvorostov, Jason S. Hong, Y. Oktay +13 more
2011EMBO Journal488 citations Open access
Semantic Scholar
Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal
Jin Zhang, Esther Nuebel, G. Daley, C. Koehler +1 more
2012Cell Stem Cell469 citations Open access
Semantic Scholar
Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria.
E. Area‐Gomez, A. de Groof, I. Boldogh, T. Bird +7 more
2009American Journal of Pathology393 citations Open access
Semantic Scholar
PNPASE Regulates RNA Import into Mitochondria
Geng Wang, Hsiao-Wen Chen, Y. Oktay, Jin Zhang +10 more
2010Cell361 citations Open access
Semantic Scholar
The Complexity of Cardiolipin in Health and Disease
S. Claypool, C. Koehler
2011TIBS -Trends in Biochemical Sciences. Regular ed359 citations Open access
Semantic Scholar
Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane
S. Claypool, Y. Oktay, P. Boontheung, J. Loo +1 more
2008Journal of Cell Biology323 citations Open access
Semantic Scholar
Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells
Jin Zhang, Esther Nuebel, D. Wisidagama, Kiyoko Setoguchi +7 more
2012Nature Protocols284 citations Open access
Semantic Scholar
MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria
Y. Zaltsman, Liat Shachnai, N. Yivgi-Ohana, Michal Schwarz +15 more
2010Nature Cell Biology219 citations Open access
Semantic Scholar
In vivo imaging of mitochondrial membrane potential in non-small cell lung cancer
M. Momcilovic, Anthony E. Jones, Sean T. Bailey, Christopher M. Waldmann +16 more
2019Nature185 citations Open access
Semantic Scholar
A role for cytochrome c and cytochrome c peroxidase in electron shuttling from Erv1
Deepa V. Dabir, Edward P. Leverich, Sung-Kun Kim, Frederick D. Tsai +3 more
2007EMBO Journal174 citations Open access
Semantic Scholar
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer
Ming-Qi Han, E. Bushong, Mayuko Segawa, Alexandre Tiard +23 more
2023Nature155 citations Open access
Semantic Scholar
Mitochondrial mislocalization and altered assembly of a cluster of Barth syndrome mutant tafazzins
S. Claypool, J. McCaffery, C. Koehler
2006Journal of Cell Biology154 citations Open access
Semantic Scholar
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development.
G. Lu, Shu-Xun Ren, P. Korge, Jayoung Choi +5 more
2007Genes & Development150 citations Open access
Semantic Scholar
Mammalian Polynucleotide Phosphorylase Is an Intermembrane Space RNase That Maintains Mitochondrial Homeostasis
Hsiao-Wen Chen, Robert N. Rainey, Cynthia E. Balatoni, David W. Dawson +7 more
2006Molecular and Cellular Biology149 citations Open access
Semantic Scholar
Correcting human mitochondrial mutations with targeted RNA import
Geng Wang, E. Shimada, Jin Zhang, Jason S. Hong +3 more
2012Proceedings of the National Academy of Sciences of the United States of America124 citations Open access
Semantic Scholar
Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells
Ting-Hsiang Wu, Enrico Sagullo, Dana Case, Xin Zheng +11 more
2016Cell Metabolism118 citations Open access
Semantic Scholar
A New Function in Translocation for the Mitochondrial i-AAA Protease Yme1: Import of Polynucleotide Phosphorylase into the Intermembrane Space
Robert N. Rainey, Jenny D. Glavin, Hsiao-Wen Chen, S. French +2 more
2006Molecular and Cellular Biology116 citations Open access
Semantic Scholar
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS)
S. Sangwan, A. Zhao, Katrina L. Adams, Christina Jayson +14 more
2017Proceedings of the National Academy of Sciences of the United States of America101 citations Open access
Semantic Scholar
A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss.
Simon von Ameln, Geng Wang, Redouane Boulouiz, M. Rutherford +20 more
2012American Journal of Human Genetics99 citations Open access
Semantic Scholar
A Small Molecule Inhibitor of Redox-Regulated Protein Translocation into Mitochondria
Deepa V. Dabir, Samuel A. Hasson, Kiyoko Setoguchi, Meghan E. Johnson +6 more
2013Developmental Cell94 citations Open access
Semantic Scholar
Redox Pathways of the Mitochondrion
C. Koehler, Kristen N Beverly, Edward P. Leverich
2006Antioxidants and Redox Signaling94 citations
Semantic Scholar
PNPASE and RNA Trafficking into Mitochondria
Geng Wang, E. Shimada, C. Koehler, M. Teitell
2011Biochimica et Biophysica Acta87 citations Open access
Semantic Scholar
Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 Pathway
Shankar Thangamani, Matthew Maland, Haroon Mohammad, Pete E. Pascuzzi +4 more
2017Frontiers in Cellular and Infection Microbiology86 citations Open access
Semantic Scholar
Loss of function of SLC25A46 causes lethal congenital pontocerebellar hypoplasia.
Ji-Jun Wan, Janos Steffen, Michael Yourshaw, H. Mamsa +13 more
2016Brain : a journal of neurology85 citations Open access
Semantic Scholar
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
H. Tienson, Deepa V. Dabir, Sonya E. Neal, R. Ogorzalek Loo +5 more
2009Molecular Biology of the Cell78 citations Open access
Semantic Scholar
Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase
Natalia Gebert, A. Chacińska, K. Wagner, B. Guiard +4 more
2008EMBO Reports77 citations Open access
Semantic Scholar
The Tim8–Tim13 complex has multiple substrate binding sites and binds cooperatively to Tim23
Kristen N Beverly, M. Sawaya, E. Schmid, C. Koehler
2008Journal of Molecular Biology77 citations Open access
Semantic Scholar
Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria
Janos Steffen, A. Vashisht, Ji-Jun Wan, J. Jen +3 more
2017Molecular Biology of the Cell74 citations Open access
Semantic Scholar
Defining functional classes of Barth syndrome mutation in humans.
Ya-Wen Lu, L. Galbraith, Jenny D Herndon, Ya-Lin Lu +9 more
2016Human Molecular Genetics73 citations Open access
Semantic Scholar
Barth syndrome mutations that cause tafazzin complex lability
S. Claypool, Kevin Whited, Santi Srijumnong, Xian-Lin Han +1 more
2011Journal of Cell Biology70 citations Open access
Semantic Scholar
Redox regulation of protein folding in the mitochondrial intermembrane space
C. Koehler, H. Tienson
2008Biochimica et Biophysica Acta69 citations Open access
Semantic Scholar
Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.
G. Hildick-Smith, Jeffrey D. Cooney, C. Garone, L. Kremer +23 more
2013American Journal of Human Genetics66 citations Open access
Semantic Scholar
TMEM14C is required for erythroid mitochondrial heme metabolism.
Yvette Y. Yien, R. F. Robledo, Iman J. Schultz, Naoko Takahashi‐Makise +31 more
2014Journal of Clinical Investigation63 citations Open access
Semantic Scholar
Pharmacologic rescue of an enzyme-trafficking defect in primary hyperoxaluria 1
Non Miyata, Janos Steffen, Meghan E. Johnson, S. Fargue +2 more
2014Proceedings of the National Academy of Sciences of the United States of America61 citations Open access
Semantic Scholar
Defining the Role of Oxygen Tension in Human Neural Progenitor Fate
Yuan Xie, Jin Zhang, Ying-Yu Lin, X. Gaeta +7 more
2014Stem Cell Reports60 citations Open access
Semantic Scholar
ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release
Janos Steffen, C. Koehler
2018Journal of Cell Biology58 citations Open access
Semantic Scholar
Tim54p connects inner membrane assembly and proteolytic pathways in the mitochondrion
David K. Hwang, S. Claypool, D. Leuenberger, H. Tienson +1 more
2007Journal of Cell Biology50 citations Open access
Semantic Scholar
Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation
Samuel A. Hasson, R. Damoiseaux, Jenny D. Glavin, Deepa V. Dabir +2 more
2010Proceedings of the National Academy of Sciences of the United States of America49 citations Open access
Semantic Scholar
Human polynucleotide phosphorylase: location matters.
Hsiao-Wen Chen, C. Koehler, M. Teitell
2007Trends in Cell Biology48 citations
Semantic Scholar
Contiguous X-chromosome Deletion Syndrome Encompassing the BTK, TIMM8A, TAF7L, and DRP2 Genes
A. Šedivá, C. Edvard Smith, A. Asplund, J. Hadač +11 more
2007Journal of Clinical Immunology42 citations
Semantic Scholar
FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity
Yvette Y. Yien, Jia-Hai Shi, Caiyong Chen, Jesmine T. M. Cheung +20 more
2018Journal of Biological Chemistry41 citations Open access
Semantic Scholar
The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model
S. Curado, E. Ober, Susan Walsh, Paulina Cortés-Hernández +3 more
2010Disease Models & Mechanisms39 citations Open access
Semantic Scholar
Meiosis I Arrest Abnormalities Lead to Severe Oligozoospermia in Meiosis 1 Arresting Protein (M1ap)-Deficient Mice1
N. Arango, L. Li, Deepa V. Dabir, F. Nicolau +5 more
2013Biology of Reproduction38 citations Open access
Semantic Scholar
Stendomycin selectively inhibits tIM23-dependent mitochondrial protein import
I. Filipuzzi, Janos Steffen, Mitchel Germain, Laetitia Goepfert +9 more
2017Nature Chemical Biology31 citations Open access
Semantic Scholar
Osm1 facilitates the transfer of electrons from Erv1 to fumarate in the redox-regulated import pathway in the mitochondrial intermembrane space
Sonya E. Neal, Deepa V. Dabir, Juwina Wijaya, Cennyana Boon +1 more
2017Molecular Biology of the Cell30 citations Open access
Semantic Scholar
Functional Characterization of a Mitochondrial Ser/Thr Protein Phosphatase in Cell Death Regulation
G. Lu, Hai-Peng Sun, P. Korge, C. Koehler +2 more
2009Methods in Enzymology30 citations Open access
Semantic Scholar
Role of Twin Cys-Xaa9-Cys Motif Cysteines in Mitochondrial Import of the Cytochrome c Oxidase Biogenesis Factor Cmc1*
M. Bourens, Deepa V. Dabir, H. Tienson, I. Sorokina +2 more
2012Journal of Biological Chemistry29 citations Open access
Semantic Scholar
P53 Regulates Rapid Apoptosis in Human Pluripotent Stem Cells
Kiyoko Setoguchi, Tara A. TeSlaa, C. Koehler, M. Teitell
2015Journal of Molecular Biology28 citations Open access
Semantic Scholar
The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity.
S. French, David W. Dawson, Hsiao-Wen Chen, Robert N. Rainey +7 more
2007Cancer Letters26 citations
Semantic Scholar

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