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A. Skupin · SciRah

Researcher profile · Semantic Scholar

A. Skupin

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A. Skupin — researcher profile on SciRah

h-index: 35
Works: 144
Citations: 4,980

Most-cited papers

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
A. Dirkse, A. Gołȩbiewska, T. Buder, P. Nazarov +18 more
2019Nature Communications472 citations Open access
Semantic Scholar
Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures
Carole Sousa, A. Gołȩbiewska, S. Poovathingal, T. Kaoma +9 more
2018EMBO Reports256 citations Open access
Semantic Scholar
The Contribution of Microglia to Neuroinflammation in Parkinson’s Disease
Katja Badanjak, Sonja Fixemer, Semra Smajić, A. Skupin +1 more
2021International Journal of Molecular Sciences235 citations Open access
Semantic Scholar
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology
A. Gołȩbiewska, A. Hau, A. Oudin, D. Stieber +37 more
2020Acta Neuropathologica137 citations Open access
Semantic Scholar
IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer
E. Koncina, M. Nurmik, V. I. Pozdeev, C. Gilson +24 more
2023Nature Communications132 citations Open access
Semantic Scholar
Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality
Jonas Walter, S. Bolognin, Paul M. A. Antony, Sarah Nickels +15 more
2019Stem Cell Reports88 citations Open access
Semantic Scholar
Mitochondrial morphology provides a mechanism for energy buffering at synapses
Guadalupe C. Garcia, T. Bartol, Sébastien Phan, E. Bushong +4 more
2019Scientific Reports82 citations Open access
Semantic Scholar
Mutations in RHOT1 Disrupt Endoplasmic Reticulum–Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease
Dajana Grossmann, Clara Berenguer-Escuder, Marie E Bellet, D. Scheibner +16 more
2019Antioxidants and Redox Signaling81 citations Open access
Semantic Scholar
SARS-CoV-2 transmission risk from asymptomatic carriers: Results from a mass screening programme in Luxembourg
P. Wilmes, J. Zimmer, Jasmin Schulz, F. Glod +12 more
2021The Lancet Regional Health - Europe76 citations Open access
Semantic Scholar
New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome
E. Tiraboschi, S. Martina, Wietske Ent, K. Grzyb +10 more
2020Epilepsia67 citations Open access
Semantic Scholar
ROS networks: designs, aging, Parkinson’s disease and precision therapies
A. Kolodkin, R. Sharma, A. Colangelo, A. Ignatenko +13 more
2020npj Systems Biology and Applications67 citations Open access
Semantic Scholar
Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression
Alise Zagare, Kyriaki Barmpa, Semra Smajić, Lisa M. Smits +5 more
2022American Journal of Human Genetics64 citations Open access
Semantic Scholar
Roles of bacteriophages, plasmids and CRISPR immunity in microbial community dynamics revealed using time-series integrated meta-omics
Susana Martínez Arbas, S. Narayanasamy, Malte Herold, L. Lebrun +19 more
2020Nature Microbiology63 citations Open access
Semantic Scholar
Model-based assessment of COVID-19 epidemic dynamics by wastewater analysis
Daniele Proverbio, Françoise Kemp, S. Magni, Leslie Ogorzaly +4 more
2022Science of the Total Environment56 citations Open access
Semantic Scholar
MIC‐MAC: An automated pipeline for high‐throughput characterization and classification of three‐dimensional microglia morphologies in mouse and human postmortem brain samples
L. Salamanca, N. Mechawar, K. Murai, R. Balling +2 more
2019Glia54 citations Open access
Semantic Scholar
Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
Lisa M. Smits, S. Magni, K. Kinugawa, K. Grzyb +7 more
2019Cell and Tissue Research46 citations Open access
Semantic Scholar
Single-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway
Oihane Uriarte Huarte, Dimitrios Kyriakis, T. Heurtaux, Y. Pires-Afonso +6 more
2021Frontiers in Immunology44 citations Open access
Semantic Scholar
The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1.
Jonas Walter, S. Bolognin, S. Poovathingal, S. Magni +24 more
2021Cell Reports42 citations Open access
Semantic Scholar
Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females
Christophe M. Capelle, S. Ciré, F. Hedin, Maxime Hansen +21 more
2023Nature Communications36 citations Open access
Semantic Scholar
Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease
G. Novak, Dimitrios Kyriakis, K. Grzyb, Michela Bernini +4 more
2022Communications Biology36 citations Open access
Semantic Scholar
Modelling COVID-19 dynamics and potential for herd immunity by vaccination in Austria, Luxembourg and Sweden
Françoise Kemp, Daniele Proverbio, A. Aalto, Laurent Mombaerts +6 more
2021Journal of Theoretical Biology34 citations Open access
Semantic Scholar
Morphological principles of neuronal mitochondria
Rachel Mendelsohn, Guadalupe C. Garcia, T. Bartol, Christopher T. Lee +11 more
2021bioRxiv31 citations Open access
Semantic Scholar
Stress hormone signalling inhibits Th1 polarization in a CD4 T‐cell‐intrinsic manner via mTORC1 and the circadian gene PER1
Christophe M. Capelle, Anna Chen, Ni Zeng, A. Baron +5 more
2022Immunology29 citations Open access
Semantic Scholar
The benefits, costs and feasibility of a low incidence COVID-19 strategy
T. Czypionka, Emil N. Iftekhar, Barbara Prainsack, V. Priesemann +19 more
2022The Lancet Regional Health - Europe25 citations Open access
Semantic Scholar
Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
Sonja Fixemer, Corrado Ameli, G. Hammer, L. Salamanca +7 more
2022Acta Neuropathologica Communications24 citations Open access
Semantic Scholar
Systematic analysis and optimization of early warning signals for critical transitions using distribution data
Daniele Proverbio, A. Skupin, Jorge M. Gonçalves
2022bioRxiv24 citations Open access
Semantic Scholar
Elucidating tumour‐associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency
Y. Pires-Afonso, A. Muller, K. Grzyb, A. Oudin +11 more
2022Molecular Oncology22 citations Open access
Semantic Scholar
Formate promotes invasion and metastasis in reliance on lipid metabolism.
Catherine Delbrouck, N. Kiweler, O. Chen, V. I. Pozdeev +23 more
2023Cell Reports21 citations Open access
Semantic Scholar
Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients
A. Grosse-Wilde, R. Kuestner, Stephanie M Skelton, Ellie MacIntosh +5 more
2018OncoTarget19 citations Open access
Semantic Scholar
Dynamical SPQEIR model assesses the effectiveness of non-pharmaceutical interventions against COVID-19 epidemic outbreaks
Daniele Proverbio, Françoise Kemp, S. Magni, A. Husch +6 more
2020PLoS ONE18 citations Open access
Semantic Scholar
CaSiAn: a Calcium Signaling Analyzer tool
Mahsa Moein, K. Grzyb, Teresa Gonçalves Martins, Shinya Komoto +4 more
2018Bioinform.17 citations Open access
Semantic Scholar
Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response.
Tijana Randic, S. Magni, D. Philippidou, C. Margue +8 more
2023Cell Reports15 citations Open access
Semantic Scholar
Multi-omics integration of scRNA-seq time series data predicts new intervention points for Parkinson’s disease
Katarina Mihajlović, G. Ceddia, N. Malod-Dognin, G. Novak +3 more
2023bioRxiv15 citations Open access
Semantic Scholar
Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies
Muhammad Ali, Oihane Uriarte Huarte, T. Heurtaux, Pierre Garcia +6 more
2022Molecular Neurobiology15 citations Open access
Semantic Scholar
A Statistical View on Calcium Oscillations.
J. Powell, M. Falcke, A. Skupin, Tomas C. Bellamy +2 more
2019Advances in Experimental Medicine and Biology15 citations Open access
Semantic Scholar
A cut finite element method for spatially resolved energy metabolism models in complex neuro-cell morphologies with minimal remeshing
S. Fariña, S. Claus, J. Hale, A. Skupin +1 more
2021Advanced Modeling and Simulation in Engineering Sciences14 citations Open access
Semantic Scholar
COVID-19 crisis management in Luxembourg: Insights from an epidemionomic approach
M. Burzyński, Joël Machado, A. Aalto, M. Beine +9 more
2020Economics and Human Biology14 citations Open access
Semantic Scholar
Combinatorial analysis reveals highly coordinated early-stage immune reactions that predict later antiviral immunity in mild COVID-19 patients
Christophe M. Capelle, S. Ciré, O. Domingues, I. Ernens +21 more
2022Cell Reports Medicine13 citations Open access
Semantic Scholar
On the phase space structure of IP3 induced Ca2+ signalling and concepts for predictive modeling.
M. Falcke, Mahsa Moein, Agnė Tilūnaitė, Rüdiger Thul +1 more
2018Chaos13 citations Open access
Semantic Scholar
Calcium-mediated mitochondrial energy deficiency in Parkinson's and Alzheimer's diseases: Insights from computational modelling
Valérie Voorsluijs, A. Skupin
2025Current Opinion in Systems Biology7 citations Open access
Semantic Scholar
MONFIT: multi-omics factorization-based integration of time-series data sheds light on Parkinson’s disease
Katarina Mihajlović, N. Malod-Dognin, Corrado Ameli, A. Skupin +1 more
2024bioRxiv7 citations Open access
Semantic Scholar
Seizure-induced increase in microglial cell population in the developing zebrafish brain.
T. Martins, Remon Soliman, M. L. Cordero-Maldonado, Cristina Donato +5 more
2023Epilepsy Research7 citations Open access
Semantic Scholar
Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation
Yu-Juan Gui, K. Grzyb, Mélanie H. Thomas, Jochen Ohnmacht +5 more
2020Epigenetics & Chromatin7 citations Open access
Semantic Scholar
Material of : Data-driven dynamical model indicates that the heat shock response in Chlamydomonas reinhardtii is tailored to handle natural temperature variation
S. Magni, Antonella Succurro, A. Skupin, O. Ebenhöh
20187 citations
Semantic Scholar
Smoothing unadjusted Langevin algorithms for nonsmooth composite potential functions
Susan Ghaderi, Masoud Ahookhosh, A. Arany, A. Skupin +2 more
2024Applied Mathematics and Computation6 citations Open access
Semantic Scholar
Mechanistic multiscale modelling of energy metabolism in human astrocytes reveals the impact of morphology changes in Alzheimer’s Disease
Sofia Farina, Valérie Voorsluijs, Sonja Fixemer, David S. Bouvier +4 more
2023PLoS Comput. Biol.6 citations Open access
Semantic Scholar
l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain
Remon Soliman, M. L. Cordero-Maldonado, T. Martins, Mahsa Moein +6 more
2021Frontiers in Genetics6 citations Open access
Semantic Scholar
Poster Presentation
T. Molloy, A. Parkin, A. Chou, J. Samra +9 more
2019Experimental animals6 citations Open access
Semantic Scholar
Buffering variability in cell regulation motifs close to criticality.
Daniele Proverbio, A. Montanari, A. Skupin, Jorge M. Gonçalves
2022Physical Review E5 citations Open access
Semantic Scholar
Assessing suppression strategies against epidemic outbreaks like COVID-19: the SPQEIR model
Daniele Proverbio, Françoise Kemp, S. Magni, A. Husch +6 more
2020medRxiv5 citations Open access
Semantic Scholar

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