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A. Reichel · SciRah

Researcher profile · Semantic Scholar

A. Reichel

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A. Reichel — researcher profile on SciRah

h-index: 30
Works: 93
Citations: 3,533

Most-cited papers

Transplantation of human islets without immunosuppression
B. Ludwig, A. Reichel, A. Steffen, B. Zimerman +11 more
2013Proceedings of the National Academy of Sciences of the United States of America264 citations Open access
Semantic Scholar
Current Aspects in the Pathophysiology and Treatment of Chronic Wounds in Diabetes Mellitus
E. Tsourdi, A. Barthel, H. Rietzsch, A. Reichel +1 more
2013BioMed Research International219 citations Open access
Semantic Scholar
Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist
B. Ludwig, A. Rotem, Janine Schmid, G. Weir +21 more
2012Proceedings of the National Academy of Sciences of the United States of America176 citations Open access
Semantic Scholar
Addressing Central Nervous System (CNS) Penetration in Drug Discovery: Basics and Implications of the Evolving New Concept
A. Reichel
2009Chemistry and Biodiversity169 citations
Semantic Scholar
Interaction of Poly(butylcyanoacrylate) Nanoparticles with the Blood-Brain Barrier in vivo and in vitro
Renad N. Alyaudtin, A. Reichel, R. Löbenberg, P. Ramge +2 more
2001Journal of drug targeting (Print)164 citations
Semantic Scholar
Closing the Gaps: A Full Scan of the Intestinal Expression of P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 in Male and Female Rats
C. Maclean, Ursula Moenning, A. Reichel, G. Fricker
2008Drug Metabolism And Disposition151 citations
Semantic Scholar
Mechanism-Based Inhibition: Deriving KI and kinact Directly from Time-Dependent IC50 Values
Ben-Fillippo Krippendorff, R. Neuhaus, P. Lienau, A. Reichel +1 more
2009Journal of biomolecular screening148 citations Open access
Semantic Scholar
The Lab Oddity Prevails: Discovery of Pan‐CDK Inhibitor (R)‐S‐Cyclopropyl‐S‐(4‐{[4‐{[(1R,2R)‐2‐hydroxy‐1‐methylpropyl]oxy}‐5‐(trifluoromethyl)pyrimidin‐2‐yl]amino}phenyl)sulfoximide (BAY 1000394) for the Treatment of Cancer
U. Lücking, R. Jautelat, Martin Krüger, T. Brumby +8 more
2013ChemMedChem146 citations
Semantic Scholar
The role of blood-brain barrier studies in the pharmaceutical industry.
A. Reichel
2006Current drug metabolism139 citations
Semantic Scholar
An overview of in vitro techniques for blood-brain barrier studies.
A. Reichel, D. Begley, N. Abbott
2003Methods in Molecular Medicine127 citations
Semantic Scholar
An international multicenter study comparing EUS-guided pancreatic duct drainage with enteroscopy-assisted endoscopic retrograde pancreatography after Whipple surgery.
Yen-I Chen, M. Levy, T. Moreels, Gulara Hajijeva +15 more
2016Gastrointestinal Endoscopy121 citations
Semantic Scholar
Drug resistance in epilepsy: the role of the blood-brain barrier.
N. Abbott, Ehsan Khan, C. Rollinson, A. Reichel +4 more
2002Novartis Foundation symposium112 citations
Semantic Scholar
Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes
B. Ludwig, S. Ludwig, A. Steffen, Y. Knauf +19 more
2017Proceedings of the National Academy of Sciences of the United States of America108 citations Open access
Semantic Scholar
Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain—a Game Changing Parameter for CNS Drug Discovery and Development
I. Loryan, A. Reichel, Bo Feng, C. Bundgaard +14 more
2022Pharmaceutical Research105 citations Open access
Semantic Scholar
Potential of Immobilized Artificial Membranes for Predicting Drug Penetration Across the Blood−Brain Barrier
A. Reichel, D. Begley
1998Pharmaceutical Research105 citations
Semantic Scholar
Pharmacokinetics in Drug Discovery: An Exposure-Centred Approach to Optimising and Predicting Drug Efficacy and Safety.
A. Reichel, P. Lienau
2016Handbook of Experimental Pharmacology82 citations
Semantic Scholar
Characterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female Rats
Doreen Mitschke, A. Reichel, G. Fricker, Ursula Moenning
2008Drug Metabolism And Disposition74 citations
Semantic Scholar
Trends in Molecular Properties, Bioavailability, and Permeability across the Bayer Compound Collection.
Daniel H. O' Donovan, C. De Fusco, Lara Kuhnke, A. Reichel
2023Journal of Medicinal Chemistry66 citations
Semantic Scholar
Endoscopic ultrasonography-guided drainage for patients with symptomatic obstruction and enlargement of the pancreatic duct.
U. Will, A. Reichel, F. Fueldner, F. Meyer
2015World Journal of Gastroenterology66 citations Open access
Semantic Scholar
Development and Application of Physiologically Based Pharmacokinetic‐Modeling Tools to Support Drug Discovery
C. Lüpfert, A. Reichel
2005Chemistry and Biodiversity60 citations
Semantic Scholar
Incidence of Bleeding in 8172 Percutaneous Ultrasound-Guided Intraabdominal Diagnostic and Therapeutic Interventions – Results of the Prospective Multicenter DEGUM Interventional Ultrasound Study (PIUS Study)
D. Strobel, T. Bernatik, W. Blank, U. Will +29 more
2015Ultraschall in der Medizin59 citations
Semantic Scholar
Optimizing Classification of Drug-Drug Interaction Potential for CYP450 Isoenzyme Inhibition Assays in Early Drug Discovery
Ben-Fillippo Krippendorff, P. Lienau, A. Reichel, W. Huisinga
2007Journal of biomolecular screening55 citations Open access
Semantic Scholar
Clinical Recommendations for the Use of the Ambulatory Glucose Profile in Diabetes Care
J. Kröger, A. Reichel, T. Siegmund, R. Ziegler
2019Journal of Diabetes Science and Technology50 citations Open access
Semantic Scholar
Piperidine renin inhibitors: from leads to drug candidates.
H. Marki, Alfred Binggeli, B. Bittner, V. Bohner-Lang +42 more
2001Il Farmaco48 citations
Semantic Scholar
Regulatory T cells control the transition from acute into chronic inflammation in glucose-6-phosphate isomerase-induced arthritis
O. Frey, A. Reichel, K. Bonhagen, L. Morawietz +2 more
2010Annals of the Rheumatic Diseases45 citations
Semantic Scholar
N-glycosylation of ABC transporters is associated with functional activity in sandwich-cultured rat hepatocytes.
Viola Draheim, A. Reichel, W. Weitschies, Ursula Moenning
2010European Journal of Pharmaceutical Sciences42 citations
Semantic Scholar
A Mechanistic Pharmacodynamic Modeling Framework for the Assessment and Optimization of Proteolysis Targeting Chimeras (PROTACs)
R. Haid, A. Reichel
2023Pharmaceutics40 citations Open access
Semantic Scholar
Quantitation of Lysosomal Trapping of Basic Lipophilic Compounds Using In Vitro Assays and In Silico Predictions Based on the Determination of the Full pH Profile of the Endo-/Lysosomal System in Rat Hepatocytes
Maximilian V. Schmitt, P. Lienau, G. Fricker, A. Reichel
2018Drug Metabolism And Disposition39 citations
Semantic Scholar
In Vitro Models of CNS Barriers
N. J. Abbott, Diana E. M. Dolman, Siti R. Yusof, A. Reichel
201436 citations
Semantic Scholar
A Probabilistic Approach to Classifying Metabolic Stability
A. Schwaighofer, Timon Schroeter, S. Mika, Katja Hansen +5 more
2008Journal of Chemical Information and Modeling36 citations
Semantic Scholar
Functional characterisation of nucleoside transport in rat brain endothelial cells
M. Chishty, D. Begley, J. Abbott, A. Reichel
2003NeuroReport29 citations
Semantic Scholar
Carrier-Mediated Delivery of Metabotropic Glutamate Receptor Ligands to the Central Nervous System: Structural Tolerance and Potential of the l-system Amino Acid Transporter at the Blood-Brain Barrier
A. Reichel, David J. Begley, N. Abbott
2000Journal of Cerebral Blood Flow and Metabolism29 citations
Semantic Scholar
Simple high-performance liquid chromatographic analysis of free primary amino acid concentrations in rat plasma and cisternal cerebrospinal fluid.
D. Begley, A. Reichel, A. Ermisch
1994Journal of chromatography. B, Biomedical applications29 citations
Semantic Scholar
Development of a fluorescence-based assay for drug interactions with human Multidrug Resistance Related Protein (MRP2; ABCC2) in MDCKII-MRP2 membrane vesicles.
C. Lechner, Valeska Reichel, Ursula Moenning, A. Reichel +1 more
2010European journal of pharmaceutics and biopharmaceutics28 citations
Semantic Scholar
Islet Transplantation at the Dresden Diabetes Center: Five Years’ Experience
B. Ludwig, A. Reichel, A. Kruppa, S. Ludwig +3 more
2014Hormone and Metabolic Research26 citations Open access
Semantic Scholar
Regional absorption of fexofenadine in rat intestine.
C. Maclean, Ursula Moenning, A. Reichel, G. Fricker
2010European Journal of Pharmaceutical Sciences24 citations
Semantic Scholar
Current Approaches for Predicting Human PK for Small Molecule Development Candidates: Findings from the IQ Human PK Prediction Working Group Survey
Carl Petersson, Xin Zhou, Joerg Berghausen, D. Cebrián +17 more
2022AAPS Journal22 citations
Semantic Scholar
Arginine vasopressin reduces the blood-brain transfer of L-tyrosine and L-valine: further evidence of the effect of the peptide on the L-system transporter at the blood-brain barrier.
A. Reichel, D. Begley, A. Ermisch
1996Brain Research22 citations
Semantic Scholar
Quantitative molecular tissue atlas of Bis(monoacylglycero)phosphate and phosphatidylglycerol membrane lipids in rodent organs generated by methylation assisted high resolution mass spectrometry.
Xueying Wang, Maximilian V. Schmitt, Li-Na Xu, Yu-Pei Jiao +4 more
2019Analytica Chimica Acta20 citations
Semantic Scholar
Evaluation of the RBE4 Cell Line to Explore Carrier-mediated Drug Delivery to the CNS Via the L-system Amino Acid Transporter At the Blood-Brain Barrier
A. Reichel, N. Abbott, D. Begley
2002Journal of drug targeting (Print)19 citations
Semantic Scholar
Pharmacokinetics of CNS Penetration
A. Reichel
201518 citations Open access
Semantic Scholar
Concentration Dependence of the Unbound Partition Coefficient Kpuu and Its Application to Correct for Exposure-Related Discrepancies between Biochemical and Cellular Potency of KAT6A Inhibitors
Cornelius Trünkle, C. Lechner, D. Korr, Léa Bouché +4 more
2020Drug Metabolism And Disposition16 citations Open access
Semantic Scholar
Modulation of the pancreatic islet-stress axis as a novel potential therapeutic target in diabetes mellitus.
B. Ludwig, A. Barthel, A. Reichel, N. Block +3 more
2014Vitamins and hormones16 citations
Semantic Scholar
Autologous derived, platelet-rich plasma gel in the treatment of nonhealing diabetic foot ulcer: a case report
Torsten Slesaczeck, H. Paetzold, T. Nanning, A. Reichel +3 more
2012Therapeutic Advances in Endocrinology and Metabolism16 citations Open access
Semantic Scholar
Extension of the Mechanistic Tissue Distribution Model of Rodgers and Rowland by Systematic Incorporation of Lysosomal Trapping: Impact on Unbound Partition Coefficient and Volume of Distribution Predictions in the Rat
Maximilian V. Schmitt, A. Reichel, Xiao-Hui Liu, G. Fricker +1 more
2020Drug Metabolism And Disposition15 citations Open access
Semantic Scholar
Pharmacokinetic Challenges in Drug Discovery
O. Pelkonen, A. Baumann, A. Reichel
2002Ernst Schering Research Foundation workshop15 citations
Semantic Scholar
Potential and Limits of Kidney Cells for Evaluation of Renal Excretion
C. Lechner, U. Mönning, A. Reichel, G. Fricker
2021Pharmaceuticals14 citations Open access
Semantic Scholar
Self-Adjustment of Insulin Dose Using Graphically Depicted Self-Monitoring of Blood Glucose Measurements in Patients with Type 1 Diabetes Mellitus
A. Reichel, H. Rietzsch, B. Ludwig, Katrin Röthig +2 more
2013Journal of Diabetes Science and Technology14 citations Open access
Semantic Scholar
Interaction of Nucleoside Analogues with Nucleoside Transporters in Rat Brain Endothelial Cells
M. Chishty, D. Begley, N. Abbott, A. Reichel
2004Journal of drug targeting (Print)14 citations
Semantic Scholar
Optimizing insulin pump therapy: the potential advantages of using a structured diabetes management program
K. Lange, R. Ziegler, A. Neu, T. Reinehr +9 more
2015Current Medical Research and Opinion13 citations
Semantic Scholar

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