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H. Marki · SciRah

Researcher profile · Semantic Scholar

H. Marki

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H. Marki — researcher profile on SciRah

h-index: 16
Works: 44
Citations: 861

Most-cited papers

A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor- (cid:1) (PPAR (cid:1) ) Recruits PPAR (cid:1) -Coactivator-1 (cid:2) , Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro
E. Burgermeister, A. Schnoebelen, A. Flament, J. Benz +10 more
2006128 citations
Semantic Scholar
Aleglitazar, a new, potent, and balanced dual PPARalpha/gamma agonist for the treatment of type II diabetes.
A. Bénardeau, J. Benz, Alfred Binggeli, D. Blum +11 more
2009Bioorganic & Medicinal Chemistry Letters94 citations Open access
Semantic Scholar
Identification of the active‐site serine in human pancreatic lipase by chemical modification with tetrahydrolipstatin
Qiaoqian Lüthi-Peng, H. Marki, P. Hadváry
1992FEBS Letters84 citations Open access
Semantic Scholar
Substituted piperidines--highly potent renin inhibitors due to induced fit adaptation of the active site.
E. Vieira, Alfred Binggeli, V. Breu, D. Bur +10 more
1999Bioorganic & Medicinal Chemistry Letters75 citations Open access
Semantic Scholar
Structure-based design of indole propionic acids as novel PPARα/γ co-agonists
B. Kuhn, H. Hilpert, J. Benz, Alfred Binggeli +5 more
200669 citations Open access
Semantic Scholar
A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.
E. Burgermeister, A. Schnoebelen, A. Flament, J. Benz +10 more
2006Molecular Endocrinology57 citations
Semantic Scholar
Piperidine-renin inhibitors compounds with improved physicochemical properties.
R. Güller, Alfred Binggeli, V. Breu, D. Bur +12 more
1999Bioorganic & Medicinal Chemistry Letters51 citations Open access
Semantic Scholar
Piperidine renin inhibitors: from leads to drug candidates.
H. Marki, Alfred Binggeli, B. Bittner, V. Bohner-Lang +42 more
2001Il Farmaco48 citations
Semantic Scholar
Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys.
Rainer E. Martin, J. Aebi, Benoit Hornsperger, H. Krebs +12 more
2015Journal of Medicinal Chemistry44 citations Open access
Semantic Scholar
Design and Biological Evaluation of Novel, Balanced Dual PPARα/γ Agonists
U. Grether, A. Bénardeau, J. Benz, Alfred Binggeli +10 more
2009ChemMedChem29 citations
Semantic Scholar
De Novo Design, Synthesis, and In Vitro Evaluation of a New Class of Nonpeptidic Inhibitors of the Malarial Enzyme Plasmepsin II
David A. Carcache, Simone R. Hörtner, Andreas Bertogg, C. Binkert +4 more
2002ChemBioChem28 citations
Semantic Scholar
Development of a New Class of Inhibitors for the Malarial Aspartic Protease Plasmepsin II Based on a Central 7‐Azabicyclo[2.2.1]heptane Scaffold
David A. Carcache, Simone R. Hörtner, P. Seiler, F. Diederich +4 more
200325 citations
Semantic Scholar
A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro
Elke Burgermeister, A. Schnoebelen, A. Flament, J. Benz +10 more
200624 citations Open access
Semantic Scholar
A new class of inhibitors for the malarial aspartic protease plasmepsin II based on a central 11-azatricyclo[6.2.1.02,7]undeca-2,4,6-triene scaffold
David A. Carcache, Simone R. Hörtner, Andreas Bertogg, F. Diederich +4 more
200321 citations
Semantic Scholar
Synthesis of annulated pyridines as inhibitors of aldosterone synthase (CYP11B2).
Rainer E. Martin, Johannes Lehmann, Thibaut Alzieu, M. Lenz +7 more
2016Organic and biomolecular chemistry17 citations
Semantic Scholar
Synthese von diastereo‐ und enantio‐selektiv deuterierten β,ε‐, β,β‐, β,γ‐ und γ,γ‐Carotinen
H. Marki, C. H. Eugster
198116 citations
Semantic Scholar
Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors.
Yong-Fu Liu, Jun Wu, Mingwei Zhou, Wenmin Chen +21 more
2020Journal of Medicinal Chemistry15 citations Open access
Semantic Scholar
Structure-based design of indole propionic acids as novel PPARalpha/gamma co-agonists.
B. Kuhn, H. Hilpert, J. Benz, Alfred Binggeli +5 more
2006Bioorganic & Medicinal Chemistry Letters12 citations
Semantic Scholar
Channels and transporters. Mini-symposium of the Division of Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS) at the Department of Chemistry, University of Basel, May 27, 2010.
R. Dutzler, Beat Ernstb, M. Hediger, D. Keppler +3 more
2010Chimia (Basel)5 citations Open access
Semantic Scholar
From Glycosaminoglycans to Heparinoid Mimetics with Antiproliferative Activity
H. Wessel, A. Chucholowski, J. Fingerle, N. Iberg +7 more
20055 citations
Semantic Scholar
Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.
J. Aebi, Kenneth Atz, S. Ametamey, Jörg Benz +40 more
2024Chimia (Basel)4 citations Open access
Semantic Scholar
Oxidosqualene cyclase (OSC) inhibitors for the treatment of dyslipidemia
H. Dehmlow, J. Ackermann, J. Aebi, Denise Blum-Kaelin +11 more
20053 citations Open access
Semantic Scholar
Inside Cover: Design and Biological Evaluation of Novel, Balanced Dual PPARα/γ Agonists (ChemMedChem 6/2009)
U. Grether, A. Bénardeau, J. Benz, Alfred Binggeli +10 more
20092 citations Open access
Semantic Scholar
Challenges and Rewards in Medicinal Chemistry Targeting Cardiovascular and Metabolic Diseases.
Werner L. Neidhart, J. Ackermann, K. Amrein, A. Conte +7 more
2015Chimia (Basel)1 citations Open access
Semantic Scholar
Frontiers in Medicinal Chemistry – Joint German-Swiss Meeting on Medicinal Chemistry: Heidelberg, Germany, March 15–18, 2009
Werner L. Neidhart, H. Marki, P. Mohr
20091 citations Open access
Semantic Scholar
Dr. Emilio Kyburz-Haerdi 26 February 1928 – 20 July 2005
R. Imhof, H. Marki, W. Froestl, W. Hunkeler
20051 citations Open access
Semantic Scholar
In vitro pharmacological properties of a series of isoprenaline derivatives.
R. Eigenmann, W. Burkard, M. Holck, H. Marki +3 more
1989Arzneimittel-Forschung1 citations
Semantic Scholar
Synthesis and chiroptical properties of (1R,1′R)-[16,16,16,16′,16′,16′-2H6]-β,β-carotene
H. Marki, C. Eugster
19801 citations
Semantic Scholar
Challenges and Rewards in Medicinal Chemistry Targeting Cardiovascular and Metabolic Diseases.
Werner L. Neidhart, J. Ackermann, K. Amrein, A. Conte +7 more
2015Chimia (Basel)0 citations Open access
Semantic Scholar
ChannelsandTransporters Mini-SymposiumoftheDivisionofMedicinalChemistry(DMC)oftheSwissChemical Society(SCS)attheDepartmentofChemistry,UniversityofBasel,May27,2010
R. Dutzler, B. Ernst, M. Hediger, D. Keppler +4 more
20100 citations
Semantic Scholar
Channels and Transporters Mini
Raimund Dutzlera, Beat Ernstb, Matthias A. Hedigerc, Dietrich Kepplerd +3 more
20100 citations
Semantic Scholar
Cognitive neuroscience and brain imaging
Gerd Folkersa, Alumit Ishaib, Markus Rudinc, Pius August Schubigerd +3 more
20090 citations
Semantic Scholar
Drug Targeting Mini-Symposium of the Division for Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS), at the Department of Chemistry, University of Basel, May 29, 2008
R. Duncan, I. Ojima, D. Neri, N. Shimma +3 more
20080 citations Open access
Semantic Scholar
Non-invasive Imaging in Biomedical Research: Annotating Structure with Molecular Information; Molecular Imag- Ing with Pet Tracers and Animal Pet Scanners; Nuclear (pet-and Spect-) Imaging Agents from Research to Approval (perspectives from a Pharma Company Working on in Vivo Diagnostics); Cognitive
Gerd Folkersa, Alumit Ishaib, Markus Rudinc, Pius August Schubigerd +3 more
20070 citations
Semantic Scholar
Imaging in Biomedical Research Mini-Symposium of the Division for Medicinal Chemistry
Gerd Folkersa, Alumit Ishaib, Markus Rudinc, Pius August Schubigerd +3 more
20070 citations
Semantic Scholar
Frontiers in Medicinal Chemistry – Joint German-Swiss Meeting on Medicinal Chemistry: Berlin, Germany, March 18–21, 2007
Werner L. Neidhart, P. Mohr, H. Marki
20070 citations Open access
Semantic Scholar
Imaging in biomedical research : Mini-symposium of the division for medicinal chemistry (DMC) of the Swiss chemical society (SCS), at the Department of Chemistry, University of Basel, May 18, 2006
G. Folkers, A. Ishai, M. Rudin, P. Schubiger +3 more
20060 citations Open access
Semantic Scholar
A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor- (cid:1) (PPAR (cid:1) ) Recruits PPAR (cid:1) -Coactivator-1 (cid:2) , Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro
Elke Burgermeister, A. Schnoebelen, A. Flament, J. Benz +10 more
20060 citations
Semantic Scholar
Neue Schwefelsäureester von Aminozuckern
A. Chucholoẉski, M. Pech, J. Fingerle, M. Rouge +6 more
19960 citations
Semantic Scholar
Dérivés peptidiques d'acides aminés avec effet inhibiteur de la rénine
Quirico Branca, H. Marki, Werner Neidhart, H. Ramuz +1 more
19900 citations
Semantic Scholar
Dérivés du tétrahydronaphtalène et médicaments les contenant
Quirico Branca, R. Jaunin, H. Marki, Franzi Marti +1 more
19870 citations
Semantic Scholar
Ueber die Wertbestimmung des Opiums und einiger anderer Alkaloid-Drogen
H. Marki
0 citations
Semantic Scholar
Über eine neue Bestimmungsmethode des Morphins im Opium (Benzolmethode)
R. Eder, H. Marki
0 citations
Semantic Scholar

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Alfred Binggeli

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H. Hilpert — researcher profile on SciRah

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