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K. Tsumoto · SciRah

Researcher profile · Semantic Scholar

K. Tsumoto

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K. Tsumoto — researcher profile on SciRah

h-index: 61
Works: 672
Citations: 15K

Most-cited papers

Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics
R. Khetan, R. Curtis, Charlotte M. Deane, J. T. Hadsund +8 more
2022mAbs78 citations Open access
Semantic Scholar
Histone H3 Lysine 27 Crotonylation Mediates Gene Transcriptional Repression in Chromatin
Nan Liu, T. Konuma, Rajal Sharma, De-Yu Wang +27 more
2023Molecules and Cells68 citations Open access
Semantic Scholar
Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3
Seisho Kinoshita, M. Nakakido, Chinatsu Mori, Daisuke Kuroda +2 more
2022Protein Science35 citations Open access
Semantic Scholar
The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis
Motohiro Sekiya, Kenta Kainoh, T. Sugasawa, Ryunosuke Yoshino +9 more
2021Nature Communications34 citations Open access
Semantic Scholar
A glutamine sensor that directly activates TORC1
Mirai Tanigawa, Katsuyoshi Yamamoto, S. Nagatoishi, K. Nagata +4 more
2021Communications Biology30 citations Open access
Semantic Scholar
Delicate balance among thermal stability, binding affinity, and conformational space explored by single-domain VHH antibodies
Emina Ikeuchi, Daisuke Kuroda, M. Nakakido, Akikazu Murakami +1 more
2021Scientific Reports28 citations Open access
Semantic Scholar
Experimental Comparison of Bond Lifetime and Viscoelastic Relaxation in Transient Networks with Well-Controlled Structures.
T. Katashima, Ryota Kudo, Mitsuru Naito, S. Nagatoishi +4 more
2022ACS Macro Letters25 citations
Semantic Scholar
Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain
Akiko Amano, N. Sanjo, W. Araki, Y. Anraku +7 more
2023Journal of Nanobiotechnology24 citations Open access
Semantic Scholar
Structural Classification of CDR-H3 in Single-Domain VHH Antibodies.
Daisuke Kuroda, K. Tsumoto
2023Methods in molecular biology22 citations Open access
Semantic Scholar
Non-Affinity Purification of Antibodies
T. Arakawa, Yui Tomioka, Masataka Nakagawa, Chiaki Sakuma +4 more
2023Antibodies22 citations Open access
Semantic Scholar
Safe and efficient oral allergy immunotherapy using one-pot-prepared mannan-coated allergen nanoparticles.
Shunyi Li, Hiroki Toriumi, Daisuke Takahashi, Tomoko Kamasaki +11 more
2023Biomaterials21 citations Open access
Semantic Scholar
High-throughput analysis system of interaction kinetics for data-driven antibody design
Ryo Matsunaga, Kan Ujiie, M. Inagaki, Jorge Amed Fernández Pérez +4 more
2023Scientific Reports20 citations Open access
Semantic Scholar
Extracellular matrix-inspired hydrogel of hyaluronan and gelatin crosslinked via a Link module with a transglutaminase reactive sequence
Masashi Okawa, Aki Tanabe, S. Ohta, S. Nagatoishi +2 more
2022Communications Materials20 citations Open access
Semantic Scholar
PRELP Regulates Cell–Cell Adhesion and EMT and Inhibits Retinoblastoma Progression
J. Hopkins, Ken Asada, A. Leung, V. Papadaki +12 more
2022Cancers19 citations Open access
Semantic Scholar
Thermodynamic Dissection of Potency and Selectivity of Cytosolic Hsp90 Inhibitors.
Chihoko Yoshimura, S. Nagatoishi, Daisuke Kuroda, Y. Kodama +9 more
2021Journal of Medicinal Chemistry19 citations Open access
Semantic Scholar
Ladder observation of bovine serum albumin by high resolution agarose native gel electrophoresis.
Yui Tomioka, Masataka Nakagawa, Chiaki Sakuma, S. Nagatoishi +3 more
2022International Journal of Biological Macromolecules18 citations
Semantic Scholar
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
M. S. J. Lee, Takeshi Inoue, W. Ise, Julia Matsuo-Dapaah +15 more
2021Journal of Experimental Medicine18 citations Open access
Semantic Scholar
Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth
Sandra Valenciano-Bellido, José M. M. Caaveiro, M. Nakakido, Daisuke Kuroda +3 more
2023Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Novel neutralizing human monoclonal antibodies against tetanus neurotoxin
T. Minamitani, Karin Kiyose, Ryota Otsubo, Toshihiro Ito +6 more
2021Scientific Reports17 citations Open access
Semantic Scholar
Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF1.
Kori Satomi, Yuki Shibahashi, Toru Ekimoto, Atsuya Nishiyama +9 more
2021Bioorganic & Medicinal Chemistry16 citations Open access
Semantic Scholar
Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival
M. Nishinaga, H. Sugimoto, Y. Nishitani, Seina Nagai +7 more
2021Communications Biology16 citations Open access
Semantic Scholar
Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope
K. Makabe, T. Yokoyama, Shiro Uehara, Tomomi Uchikubo-Kamo +6 more
2021Scientific Reports15 citations Open access
Semantic Scholar
A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells
A. Eguchi, Ayaka Ueki, Junya Hoshiyama, K. Kuwata +6 more
2021JACS Au15 citations Open access
Semantic Scholar
Effects of network connectivity on viscoelastic relaxation in transient networks using experimental approach
T. Katashima, Ryota Kudo, Ryoya Onishi, Mitsuru Naito +5 more
2022Frontiers in Soft Matter13 citations Open access
Semantic Scholar
Human antibody recognition and neutralization mode on the NTD and RBD domains of SARS-CoV-2 spike protein
Ryota Otsubo, T. Minamitani, K. Kobiyama, J. Fujita +12 more
2022Scientific Reports13 citations Open access
Semantic Scholar
Raman Spectroscopic Analysis of Highly-Concentrated Antibodies under the Acid-Treated Conditions
Yusui Sato, S. Nagatoishi, Shintaro Noguchi, K. Tsumoto
2022Pharmaceutical Research12 citations Open access
Semantic Scholar
An integrated computational pipeline for designing high-affinity nanobodies with expanded genetic codes
A. Padhi, Ashutosh Kumar, Ken-ichi Haruna, Haruna Sato +8 more
2021Briefings Bioinform.12 citations
Semantic Scholar
Specific peptide conjugation to a therapeutic antibody leads to enhanced therapeutic potency and thermal stability by reduced Fc dynamics
Masato Kiyoshi, M. Nakakido, A. Rafique, M. Tada +8 more
2023Scientific Reports11 citations Open access
Semantic Scholar
Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer
K. Shozu, Syuzo Kaneko, Norio Shinkai, A. Dozen +9 more
2022Clinical Epigenetics11 citations Open access
Semantic Scholar
Performance Comparison of Spectral Distance Calculation Methods
Taiji Oyama, Satoko Suzuki, Y. Horiguchi, Aiko Yamane +3 more
2022Applied Spectroscopy11 citations Open access
Semantic Scholar
Structural and thermodynamical insights into the binding and inhibition of FIH-1 by the N-terminal disordered region of Mint3
T. Ten, S. Nagatoishi, Ryo Maeda, M. Hoshino +4 more
2021Journal of Biological Chemistry11 citations Open access
Semantic Scholar
An Engineered Synthetic Receptor-Aptamer Pair for an Artificial Signal Transduction System.
Hanrui Liu, T. A. Baeumler, Kai Nakamura, Yuga Okada +6 more
2023ACS Nano10 citations
Semantic Scholar
Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection
H. Akiba, J. Fujita, Tomoko Ise, Kentaro Nishiyama +7 more
2023Communications Biology10 citations Open access
Semantic Scholar
Structure and role of the linker domain of the iron surface-determinant protein IsdH in heme transportation in Staphylococcus aureus
Sandra Valenciano-Bellido, José M. M. Caaveiro, K. Morante, T. Sushko +3 more
2022Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Biophysical Characterization of the Contribution of the Fab Region to the IgG-FcγRIIIa Interaction
Hirofumi Kosuge, S. Nagatoishi, Masato Kiyoshi, A. Ishii-Watabe +3 more
2022Biochemistry10 citations Open access
Semantic Scholar
Addition of arginine hydrochloride and proline to the culture medium enhances recombinant protein expression in Brevibacillus choshinensis: The case of RBD of SARS-CoV-2 spike protein and its antibody
Ryo Matsunaga, K. Tsumoto
2022Protein Expression and Purification10 citations Open access
Semantic Scholar
Structural insights into 3Fe–4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P450
A. Gilep, T. Varaksa, Sergei Bukhdruker, A. Kavaleuski +19 more
2022bioRxiv10 citations Open access
Semantic Scholar
Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex
K. Yamaguchi, S. Nakagawa, Akari Saku, Yumiko Isobe +17 more
2023iScience9 citations Open access
Semantic Scholar
Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes
Taichi Yamazaki, S. Nagatoishi, Tsukushi Yamawaki, T. Nozawa +5 more
2023Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Analysis of bovine serum albumin unfolding in the absence and presence of ATP by SYPRO Orange staining of agarose native gel electrophoresis.
Yui Tomioka, Masataka Nakagawa, Chiaki Sakuma, Y. Kurosawa +4 more
2022Analytical Biochemistry9 citations
Semantic Scholar
Oligo(N-methylalanine) as a Peptide-Based Molecular Scaffold with a Minimal Structure and High Density of Functionalizable Sites.
Marin Yokomine, J. Morimoto, Yasuhiro Fukuda, Yota Shiratori +5 more
2022Angewandte Chemie9 citations Open access
Semantic Scholar
Electrostatic-triggered exothermic antibody adsorption to the cellulose nanoparticles.
K. Murakami, S. Nagatoishi, Keisuke Kasahara, Hirokazu Nagai +3 more
2021Analytical Biochemistry8 citations Open access
Semantic Scholar
Agarose native gel electrophoresis analysis of thermal aggregation controlled by Hofmeister series.
Yui Tomioka, Ryo Sato, R. Takahashi, S. Nagatoishi +4 more
2023Biophysical Chemistry7 citations
Semantic Scholar
Conformational features and interaction mechanisms of VHH antibodies with β‐hairpin CDR3: A case of Nb8‐HigB2 interaction
Koichi Yamamoto, S. Nagatoishi, Ryo Matsunaga, M. Nakakido +2 more
2023Protein Science7 citations Open access
Semantic Scholar
One-pot preparation of mannan-coated antigen nanoparticles using human serum albumin as a matrix for tolerance induction.
Shun-Yi Li, Daisuke Murakami, S. Nagatoishi, Yiwei Liu +3 more
2023Journal of Colloid and Interface Science7 citations Open access
Semantic Scholar
Inactivation and spike protein denaturation of novel coronavirus variants by CuxO/TiO2 nano-photocatalysts
T. Tatsuma, M. Nakakido, T. Ichinohe, Yoshinori Kuroiwa +7 more
2023Scientific Reports7 citations Open access
Semantic Scholar
Anion solvation enhanced by positive supercharging mutations preserves thermal stability of an antibody in a wide pH range.
Keisuke Kasahara, Daisuke Kuroda, Aki Tanabe, Raiji Kawade +2 more
2021Biochemical and Biophysical Research Communications - BBRC7 citations Open access
Semantic Scholar
Production of IgG1-based bispecific antibody without extra cysteine residue via intein-mediated protein trans-splicing
H. Akiba, Tomoko Ise, S. Nagata, H. Kamada +2 more
2021Scientific Reports7 citations Open access
Semantic Scholar
PDZD8-FKBP8 tethering complex at ER-mitochondria contact sites regulates mitochondrial complexity
Koki Nakamura, Saeko Aoyama-Ishiwatari, Takahiro Nagao, Mohammadreza Paaran +19 more
2024bioRxiv6 citations Open access
Semantic Scholar
PRELP secreted from mural cells protects the function of blood brain barrier through regulation of endothelial cell-cell integrity
H. Davaapil, J. Hopkins, N. Bonnin, V. Papadaki +8 more
2023Frontiers in Cell and Developmental Biology6 citations Open access
Semantic Scholar

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