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G. Kalna · SciRah

Researcher profile · Semantic Scholar

G. Kalna

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G. Kalna — researcher profile on SciRah

h-index: 38
Works: 78
Citations: 6,033

Most-cited papers

Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
Z. Schug, B. Peck, Dylan T. Jones, Qi-Feng Zhang +29 more
2015Cancer Cell790 citations Open access
Semantic Scholar
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
C. Frezza, Liang Zheng, Ori Folger, Kartik N. Rajagopalan +14 more
2011Nature491 citations
Semantic Scholar
ROS Production and NF-κB Activation Triggered by RAC1 Facilitate WNT-Driven Intestinal Stem Cell Proliferation and Colorectal Cancer Initiation
K. Myant, P. Cammareri, E. McGhee, R. Ridgway +12 more
2013Cell Stem Cell391 citations Open access
Semantic Scholar
Improving the metabolic fidelity of cancer models with a physiological cell culture medium
Johan Vande Voorde, T. Ackermann, Nadja Pfetzer, D. Sumpton +6 more
2019Science Advances339 citations Open access
Semantic Scholar
Fumarate induces redox-dependent senescence by modifying glutathione metabolism
Liang Zheng, S. Cardaci, Livnat Jerby, Elaine D. Mackenzie +13 more
2015Nature Communications278 citations Open access
Semantic Scholar
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis
S. Cardaci, Liang Zheng, G. Mackay, N. V. D. van den Broek +13 more
2015Nature Cell Biology272 citations Open access
Semantic Scholar
Metabolic Profiling of Hypoxic Cells Revealed a Catabolic Signature Required for Cell Survival
C. Frezza, Liang Zheng, D. Tennant, D. Papkovsky +4 more
2011PLoS ONE188 citations Open access
Semantic Scholar
MCL-1 is a prognostic indicator and drug target in breast cancer
K. Campbell, S. Dhayade, N. Ferrari, A. Sims +8 more
2018Cell Death and Disease174 citations Open access
Semantic Scholar
Non-commercial Research and Educational Use including without Limitation Use in Instruction at Your Institution, Sending It to Specific Colleagues That You Know, and Providing a Copy to Your Institution's Administrator. All Other Uses, Reproduction and Distribution, including without Limitation Comm
D. Higham, G. Kalna, M. Kibble
162 citations
Semantic Scholar
Nanotopographical stimulation of mechanotransduction and changes in interphase centromere positioning
M. Dalby, M. Biggs, N. Gadegaard, G. Kalna +2 more
2007Journal of Cellular Biochemistry158 citations
Semantic Scholar
Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma.
D. Costea, A. Hills, A. H. Osman, J. Thurlow +8 more
2013Cancer Research154 citations Open access
Semantic Scholar
An Improved Chamber for Direct Visualisation of Chemotaxis
A. Muinonen-Martin, Douwe M. Veltman, G. Kalna, R. Insall
2010PLoS ONE134 citations Open access
Semantic Scholar
Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells
R. Carruthers, S. Ahmed, Shaliny Ramachandran, K. Strathdee +9 more
2018Cancer Research133 citations Open access
Semantic Scholar
Melanoma Cells Break Down LPA to Establish Local Gradients That Drive Chemotactic Dispersal
A. Muinonen-Martin, O. Susanto, Qi-Feng Zhang, Elizabeth Smethurst +12 more
2014PLoS Biology127 citations Open access
Semantic Scholar
Targeting mTOR dependency in pancreatic cancer
D. C. Morran, Jian-Min Wu, N. Jamieson, Agata Mrowinska +18 more
2014Gut127 citations Open access
Semantic Scholar
ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth
N. Rath, J. Morton, L. Julian, L. Helbig +9 more
2016EMBO Molecular Medicine119 citations Open access
Semantic Scholar
Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells
Liang Zheng, Elaine D. Mackenzie, S. Karim, A. Hedley +6 more
2013Cancer & Metabolism115 citations Open access
Semantic Scholar
In vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis.
S. Zanivan, A. Meves, Kristina Behrendt, E. Schoof +12 more
2013Cell Reports107 citations Open access
Semantic Scholar
Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter.
A. Hannigan, PaulR . Smith, G. Kalna, Cristiana Lo Nigro +24 more
2010Journal of Clinical Investigation106 citations Open access
Semantic Scholar
CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer
Iain R. Macpherson, E. Rainero, Louise E. Mitchell, P. V. E. van den Berghe +7 more
2014Journal of Cell Science104 citations Open access
Semantic Scholar
Impaired neutrophil directional chemotactic accuracy in chronic periodontitis patients
Helen M. Roberts, Martin R. Ling, R. Insall, G. Kalna +3 more
2015Journal of Clinical Periodontology102 citations Open access
Semantic Scholar
E-cadherin can limit the transforming properties of activating β-catenin mutations
D. Huels, R. Ridgway, S. Radulescu, M. Leushacke +22 more
2015EMBO Journal95 citations Open access
Semantic Scholar
Colorectal tumors require NUAK1 for protection from oxidative stress
J. Port, Nathiya Muthalagu, M. Raja, Fatih Ceteci +21 more
2018Cancer Discovery91 citations Open access
Semantic Scholar
Divergent routes to oral cancer.
Keith D. Hunter, J. Thurlow, J. Fleming, P. Drake +7 more
2006Cancer Research87 citations Open access
Semantic Scholar
Antibodies to Heteromeric Glycolipid Complexes in Guillain-Barré Syndrome
S. Rinaldi, K. Brennan, G. Kalna, C. Walgaard +6 more
2013PLoS ONE81 citations Open access
Semantic Scholar
ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2
Anne von Thun, M. Birtwistle, G. Kalna, J. Grindlay +4 more
2012Journal of Cell Science80 citations Open access
Semantic Scholar
Spectral clustering of microarray data elucidates the roles of microenvironment remodeling and immune responses in survival of head and neck squamous cell carcinoma.
J. Thurlow, Claudia L. Peña Murillo, K. Hunter, F. Buffa +9 more
2010Journal of Clinical Oncology78 citations Open access
Semantic Scholar
Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis
K. Brennan, Francesc Galban-Horcajo, S. Rinaldi, C. O'Leary +9 more
2011Journal of Neuroimmunology76 citations Open access
Semantic Scholar
Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy
Francesc Galban-Horcajo, A. M. Fitzpatrick, A. Hutton, S. M. Dunn +6 more
2012European Journal of Neurology61 citations Open access
Semantic Scholar
A clustering coefficient for weighted networks, with application to gene expression data
G. Kalna, D. Higham
2007AI Communications58 citations
Semantic Scholar
A Study of the Effects of Exercise on the Urinary Metabolome Using Normalisation to Individual Metabolic Output
E. Daskalaki, G. Blackburn, G. Kalna, Tong Zhang +2 more
2015Metabolites54 citations Open access
Semantic Scholar
Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer
P. Rajan, J. Stockley, I. Sudbery, J. Fleming +9 more
2014BMC Cancer54 citations Open access
Semantic Scholar
Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells
J. Munkley, Nicholas Lafferty, G. Kalna, C. Robson +3 more
2015BMC Cancer51 citations Open access
Semantic Scholar
The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma
J. Birch, Cassie J. Clarke, A. Campbell, K. Campbell +8 more
2016Biology Open48 citations Open access
Semantic Scholar
N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis
A. Juin, H. Spence, Kirsty J. Martin, E. McGhee +12 more
2019Developmental Cell47 citations Open access
Semantic Scholar
Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization
D. Rudzka, Giulia Spennati, David J. McGarry, Y. Chim +12 more
2019Journal of Cell Science44 citations Open access
Semantic Scholar
Identification of Novel Androgen-Regulated Pathways and mRNA Isoforms through Genome-Wide Exon-Specific Profiling of the LNCaP Transcriptome
P. Rajan, Caroline Dalgliesh, Phillippa J. Carling, T. Buist +11 more
2011PLoS ONE43 citations Open access
Semantic Scholar
Mir143 expression inversely correlates with nuclear ERK5 immunoreactivity in clinical prostate cancer
Imran Ahmad, L. Singh, Z.-H. Yang, G. Kalna +8 more
2013British Journal of Cancer40 citations Open access
Semantic Scholar
Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells
John C. Dawson, P. Timpson, G. Kalna, L. Machesky
2011Oncogene38 citations Open access
Semantic Scholar
Microarray screening of Guillain-Barré syndrome sera for antibodies to glycolipid complexes
S. Halstead, G. Kalna, Mohammad B. Islam, I. Jahan +5 more
2016Neurology: Neuroimmunology & Neuroinflammation31 citations Open access
Semantic Scholar
The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells
J. Munkley, K. Livermore, U. McClurg, G. Kalna +9 more
2015Oncoscience31 citations Open access
Semantic Scholar
Upregulated FGFR1 expression is associated with the transition of hormone-naive to castrate-resistant prostate cancer
K. Armstrong, I. Ahmad, G. Kalna, Ss Tan +3 more
2011British Journal of Cancer31 citations Open access
Semantic Scholar
MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice
M. E. Healy, Yannick Boege, M. Hodder, Friederike Böhm +30 more
2020Gastroenterology28 citations Open access
Semantic Scholar
Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing
Ai Tian, H. Benchabane, Zheng-Han Wang, C. Zimmerman +7 more
2017PLoS Genetics27 citations Open access
Semantic Scholar
The Thermostat Problem
G. Kalna, S. McKee
200226 citations Open access
Semantic Scholar
Clustering Coefficients for Weighted Networks ∗ †
G. Kalna
200625 citations
Semantic Scholar
Prostate Gland Lengths and Iceball Dimensions Predict Micturition Functional Outcome Following Salvage Prostate Cryotherapy in Men with Radiation Recurrent Prostate Cancer
I. Ahmad, G. Kalna, Mohamed Ismail, F. Birrell +5 more
2013PLoS ONE21 citations Open access
Semantic Scholar
Spectral analysis of two-signed microarray expression data.
D. Higham, G. Kalna, J. Vass
2007Mathematical Medicine and Biology-a Journal of The Ima19 citations
Semantic Scholar
The thermostat problem with a nonlocal nonlinear boundary condition
G. Kalna, S. McKee
200419 citations
Semantic Scholar
Abi Is Required for Modulation and Stability but Not Localization or Activation of the SCAR/WAVE Complex
Andrew J. Davidson, S. Ura, P. Thomason, G. Kalna +1 more
2013Eukaryotic Cell17 citations Open access
Semantic Scholar

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